| Filed On | Filing |
|---|---|
| 22 Dec 2011 | Form 3/A: Sofinnova Venture Partners Vi L P, 10% owner and 7 others |
| 13 Apr 2010 |
Form 3/A: Kilfoil Georgina, SVP, Prod. Dev. & Project Mngm
Holds 87,616 shares of Common Stock |
| 30 Mar 2010 | Form 3/A: Lowe Christopher P., CFO & VP of Administration |
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