Madryn Asset Management, LP 4 SEC Filings

Acquired 30,000 shares (Other Transaction) · Acquired 42,500 shares (Other Transaction)

Acquired 337,312 shares (Gift) · Gave 337,312 shares as a gift

Bought 37,537,187 shares · Acquired 1,835,000 Voting Convertible Preferred Stock (Open Market Purchase) · Acquired 1,575,810 Senior Convertible Preferred Stock (Open Market Purchase) · 1 more

Disposed of 0 Secured Subordinated Convertible Notes (Disposition to Issuer) · Acquired 545,335 Series Y Convertible Preferred Stock (Open Market Purchase)

Sold 3,500,000 shares ($13M)

Acquired 0 Secured Subordinated Convertible Notes (Open Market Purchase) · Disposed of 0 Secured Subordinated Convertible Notes (Disposition to Issuer) · Acquired 325,651 Series Y Convertible Preferred Stock (Open Market Purchase)

Acquired 0 Secured Subordinated Convertible Notes (Open Market Purchase) · Disposed of 0 Secured Subordinated Convertible Notes (Disposition to Issuer) · Acquired 379,311 Series Y Convertible Preferred Stock (Open Market Purchase)

Acquired 203,583 Series Y Convertible Preferred Stock (Open Market Purchase)

Acquired 576,986 Series Y Convertible Preferred Stock (Open Market Purchase)

Acquired 0 Secured Subordinated Convertible Notes (Open Market Purchase) · Disposed of 0 Secured Subordinated Convertible Notes (Disposition to Issuer) · Acquired 248,755 Series X Convertible Preferred Stock (Open Market Purchase)