| Filed On | Filing |
|---|---|
| 14 Apr 2008 | SCHEDULE 13D |
| 01 Oct 2004 | SCHEDULE 13D SAMUEL D. ISALY |
| 01 Oct 2004 | SCHEDULE 13D ORBIMED CAPITAL II LLC |
| 01 Oct 2004 | SCHEDULE 13D ORBIMED ADVISORS LLC |
| 30 Mar 1998 | FORM 13-D - DAVID KATZ |
| 22 Jan 1998 | SCHEDULE 13D |
| 22 Jan 1998 | FORM 13-D - DAVID KATZ |
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