2022 Q1 Form 10-K Financial Statement

#000087401522000079 Filed on February 25, 2022

View on sec.gov

Income Statement

Concept 2022 Q1 2021 Q4 2021
Revenue $141.9M $440.0M $810.5M
YoY Change 27.17% 51.58% 11.13%
Cost Of Revenue $4.170M $2.226M $10.84M
YoY Change 60.38% -32.55% -8.89%
Gross Profit $137.7M $437.8M $799.6M
YoY Change 26.38% 52.54% 11.48%
Gross Profit Margin 97.06% 99.49% 98.66%
Selling, General & Admin $34.13M $37.60M $170.9M
YoY Change -44.24% -72.93% -51.75%
% of Gross Profit 24.77% 8.59% 21.38%
Research & Development $161.1M $179.6M $635.0M
YoY Change 15.25% 5.14% 18.66%
% of Gross Profit 116.97% 41.02% 79.41%
Depreciation & Amortization $4.293M $4.434M $17.84M
YoY Change -2.43% 3.12% 15.09%
% of Gross Profit 3.12% 1.01% 2.23%
Operating Expenses $195.3M $217.2M $805.9M
YoY Change -2.86% -29.85% -9.39%
Operating Profit -$57.50M $220.6M -$6.286M
YoY Change -37.5% -1073.37% -96.35%
Interest Expense -$6.754M $4.788M $10.80M
YoY Change -407.0% -578.8% 13.54%
% of Operating Profit 2.17%
Other Income/Expense, Net $187.0K -$477.0K -$1.133M
YoY Change -577.0% 1033.0%
Pretax Income -$64.07M $224.9M -$29.15M
YoY Change -28.6% -1053.03% -78.34%
Income Tax $1.100M $303.0K -$551.0K
% Of Pretax Income 0.13%
Net Earnings -$65.17M $224.6M -$28.60M
YoY Change -27.49% -166.01% -93.56%
Net Earnings / Revenue -45.92% 51.05% -3.53%
Basic Earnings Per Share -$0.46 $1.59 -$0.20
Diluted Earnings Per Share -$460.2K $1.41 -$202.8K
COMMON SHARES
Basic Shares Outstanding 141.7M 141.2M 141.0M
Diluted Shares Outstanding 141.6M 160.3M 141.0M

Balance Sheet

Concept 2022 Q1 2021 Q4 2021
SHORT-TERM ASSETS
Cash & Short-Term Investments $2.052B $2.115B $2.115B
YoY Change 12.77% 11.76% 11.76%
Cash & Equivalents $542.5M $869.2M $869.2M
Short-Term Investments $1.510B $1.246B $1.246B
Other Short-Term Assets $150.6M $143.4M $143.4M
YoY Change 21.63% 2.26% 2.26%
Inventory $24.03M $24.81M $24.81M
Prepaid Expenses
Receivables $26.12M $61.90M $61.90M
Other Receivables $0.00 $0.00 $0.00
Total Short-Term Assets $2.253B $2.345B $2.345B
YoY Change 13.26% 10.06% 10.06%
LONG-TERM ASSETS
Property, Plant & Equipment $177.7M $196.1M $196.1M
YoY Change -1.48% 0.96% 0.96%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets $58.95M $41.57M $41.57M
YoY Change 18.13% 12.65% 12.65%
Total Long-Term Assets $266.0M $266.6M $266.6M
YoY Change 2.61% 2.91% 2.91%
TOTAL ASSETS
Total Short-Term Assets $2.253B $2.345B $2.345B
Total Long-Term Assets $266.0M $266.6M $266.6M
Total Assets $2.519B $2.612B $2.612B
YoY Change 12.03% 9.28% 9.28%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $16.13M $11.90M $11.90M
YoY Change 69.74% -30.79% -30.79%
Accrued Expenses $115.8M $130.0M $130.0M
YoY Change 7.2% -17.69% -17.69%
Deferred Revenue $97.71M
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due $4.206M $926.0K $926.0K
YoY Change -93.95% -99.69% -99.69%
Total Short-Term Liabilities $228.5M $240.6M $240.6M
YoY Change -22.59% -58.76% -58.76%
LONG-TERM LIABILITIES
Long-Term Debt $1.248B $1.228B $1.228B
YoY Change 43.29% 134.45% 134.45%
Other Long-Term Liabilities $333.1M $371.4M $371.4M
YoY Change -17.13% -15.46% -15.46%
Total Long-Term Liabilities $1.581B $1.599B $1.599B
YoY Change 24.21% 66.07% 66.07%
TOTAL LIABILITIES
Total Short-Term Liabilities $228.5M $240.6M $240.6M
Total Long-Term Liabilities $1.581B $1.599B $1.599B
Total Liabilities $1.810B $1.840B $1.840B
YoY Change 15.4% 18.98% 18.98%
SHAREHOLDERS EQUITY
Retained Earnings -$1.160B
YoY Change 2.53%
Common Stock $1.964B
YoY Change 3.63%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $709.6M $771.7M $771.7M
YoY Change
Total Liabilities & Shareholders Equity $2.519B $2.612B $2.612B
YoY Change 12.03% 9.28% 9.28%

Cashflow Statement

Concept 2022 Q1 2021 Q4 2021
OPERATING ACTIVITIES
Net Income -$65.17M $224.6M -$28.60M
YoY Change -27.49% -166.01% -93.56%
Depreciation, Depletion And Amortization $4.293M $4.434M $17.84M
YoY Change -2.43% 3.12% 15.09%
Cash From Operating Activities -$31.65M $203.7M $30.80M
YoY Change -42.14% 107.84% -14.21%
INVESTING ACTIVITIES
Capital Expenditures -$2.705M -$2.502M -$11.96M
YoY Change 50.28% -50.94% -65.94%
Acquisitions
YoY Change
Other Investing Activities -$284.8M $97.61M $206.9M
YoY Change -453.4% -49.42% -33.18%
Cash From Investing Activities -$287.5M $95.11M $194.9M
YoY Change -464.45% -49.38% -29.0%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities -7.325M -62.49M 245.9M
YoY Change -3.62% -88.02% -141.22%
NET CHANGE
Cash From Operating Activities -31.65M 203.7M 30.80M
Cash From Investing Activities -287.5M 95.11M 194.9M
Cash From Financing Activities -7.325M -62.49M 245.9M
Net Change In Cash -326.5M 236.3M 471.6M
YoY Change -2067.01% -200.3% -265.13%
FREE CASH FLOW
Cash From Operating Activities -$31.65M $203.7M $30.80M
Capital Expenditures -$2.705M -$2.502M -$11.96M
Free Cash Flow -$28.95M $206.2M $42.75M
YoY Change -45.28% 99.99% -39.78%

Facts In Submission

Frame Concept Type Concept / XBRL Key Value Unit
CY2021 dei Amendment Flag
AmendmentFlag
false
CY2021 dei Current Fiscal Year End Date
CurrentFiscalYearEndDate
--12-31
CY2021 dei Document Fiscal Year Focus
DocumentFiscalYearFocus
2021
CY2021 dei Document Fiscal Period Focus
DocumentFiscalPeriodFocus
FY
CY2021 dei Entity Central Index Key
EntityCentralIndexKey
0000874015
CY2021 us-gaap Inventory Write Down
InventoryWriteDown
CY2020 us-gaap Inventory Write Down
InventoryWriteDown
CY2021Q4 us-gaap Operating Lease Liability Current Statement Of Financial Position Extensible List
OperatingLeaseLiabilityCurrentStatementOfFinancialPositionExtensibleList
http://ionispharma.com/20211231#LongTermObligationsExcludingConvertibleDebtCurrent
CY2021 dei Auditor Firm
AuditorFirmId
42
CY2021 dei Document Type
DocumentType
10-K
CY2021 dei Document Annual Report
DocumentAnnualReport
true
CY2021 dei Document Period End Date
DocumentPeriodEndDate
2021-12-31
CY2021 dei Document Transition Report
DocumentTransitionReport
false
CY2021 dei Entity File Number
EntityFileNumber
000-19125
CY2021 dei Entity Registrant Name
EntityRegistrantName
Ionis Pharmaceuticals, Inc
CY2021 dei Entity Incorporation State Country Code
EntityIncorporationStateCountryCode
DE
CY2021 dei Entity Tax Identification Number
EntityTaxIdentificationNumber
33-0336973
CY2021 dei Entity Address Address Line1
EntityAddressAddressLine1
2855 Gazelle Court
CY2021 dei Entity Address City Or Town
EntityAddressCityOrTown
Carlsbad
CY2021 dei Entity Address State Or Province
EntityAddressStateOrProvince
CA
CY2021 dei Entity Address Postal Zip Code
EntityAddressPostalZipCode
92010
CY2021 dei City Area Code
CityAreaCode
760
CY2021 dei Local Phone Number
LocalPhoneNumber
931-9200
CY2021 dei Security12b Title
Security12bTitle
Common Stock, $.001 Par Value
CY2021 dei Trading Symbol
TradingSymbol
IONS
CY2021 dei Security Exchange Name
SecurityExchangeName
NASDAQ
CY2021 dei Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
Yes
CY2021 dei Entity Voluntary Filers
EntityVoluntaryFilers
No
CY2021 dei Entity Current Reporting Status
EntityCurrentReportingStatus
Yes
CY2021 dei Entity Interactive Data Current
EntityInteractiveDataCurrent
Yes
CY2021 dei Entity Filer Category
EntityFilerCategory
Large Accelerated Filer
CY2021 dei Entity Small Business
EntitySmallBusiness
false
CY2021 dei Entity Emerging Growth Company
EntityEmergingGrowthCompany
false
CY2021 dei Icfr Auditor Attestation Flag
IcfrAuditorAttestationFlag
true
CY2021 dei Entity Shell Company
EntityShellCompany
false
CY2021Q2 dei Entity Public Float
EntityPublicFloat
4675204973
CY2022Q1 dei Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
141688727
CY2021 dei Auditor Name
AuditorName
Ernst & Young LLP
CY2021 dei Auditor Location
AuditorLocation
San Diego, California
CY2021Q4 ions Long Term Obligations Excluding Convertible Debt Current
LongTermObligationsExcludingConvertibleDebtCurrent
3526000
CY2020Q4 ions Long Term Obligations Excluding Convertible Debt Current
LongTermObligationsExcludingConvertibleDebtCurrent
7301000
CY2021Q4 ions Long Term Obligations Excluding Convertible Debt Noncurrent
LongTermObligationsExcludingConvertibleDebtNoncurrent
26378000
CY2020Q4 ions Long Term Obligations Excluding Convertible Debt Noncurrent
LongTermObligationsExcludingConvertibleDebtNoncurrent
23409000
CY2019 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
1.90
CY2020Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
743282000
CY2019 us-gaap Adjustments To Additional Paid In Capital Warrant Issued
AdjustmentsToAdditionalPaidInCapitalWarrantIssued
56110000
CY2019 us-gaap Adjustments To Additional Paid In Capital Other
AdjustmentsToAdditionalPaidInCapitalOther
-85860000
CY2019 us-gaap Minority Interest Period Increase Decrease
MinorityInterestPeriodIncreaseDecrease
9116000
CY2020 us-gaap Minority Interest Decrease From Redemptions
MinorityInterestDecreaseFromRedemptions
544686000
CY2020 us-gaap Stock Repurchased And Retired During Period Value
StockRepurchasedAndRetiredDuringPeriodValue
90549000
CY2020 ions Adjustments To Additional Paid In Capital Deferred Tax Liability Adjustment
AdjustmentsToAdditionalPaidInCapitalDeferredTaxLiabilityAdjustment
7714000
CY2020 us-gaap Minority Interest Period Increase Decrease
MinorityInterestPeriodIncreaseDecrease
-35480000
CY2021 us-gaap Adjustments To Additional Paid In Capital Warrant Issued
AdjustmentsToAdditionalPaidInCapitalWarrantIssued
89752000
CY2021 us-gaap Adjustments To Additional Paid In Capital Other
AdjustmentsToAdditionalPaidInCapitalOther
-136620000
CY2019 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
280560000
CY2020 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
-444464000
CY2020 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
139612000
CY2020 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-3.18
CY2019 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
139998000
CY2019 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
2.00
CY2019 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
280560000
CY2019 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
139998000
CY2019 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
2.00
CY2019 ions Incremental Common Shares Attributable To Employee Stock Purchase Plan
IncrementalCommonSharesAttributableToEmployeeStockPurchasePlan
18000
CY2019 us-gaap Net Income Loss Available To Common Stockholders Diluted
NetIncomeLossAvailableToCommonStockholdersDiluted
290947000
CY2019 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
153164000
CY2019 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
1.90
CY2020Q4 us-gaap Convertible Debt Current
ConvertibleDebtCurrent
308809000
CY2020Q4 us-gaap Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
1895519000
CY2020Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-1131306000
CY2020 us-gaap Interest Expense
InterestExpense
9510000
CY2020 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-134552000
CY2020 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
345191000
CY2020 us-gaap Profit Loss
ProfitLoss
-479743000
CY2020 us-gaap Net Income Loss
NetIncomeLoss
-444263000
CY2020 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-3.18
CY2020 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-3.18
CY2019 us-gaap Interest Expense
InterestExpense
12440000
CY2019 us-gaap Gains Losses On Extinguishment Of Debt
GainsLossesOnExtinguishmentOfDebt
-66196000
CY2019 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
338766000
CY2019 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
51507000
CY2019 us-gaap Profit Loss
ProfitLoss
287259000
CY2019 us-gaap Net Income Loss
NetIncomeLoss
278143000
CY2019 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
2.00
CY2019Q4 us-gaap Stockholders Equity Including Portion Attributable To Noncontrolling Interest
StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest
1577459000
CY2019Q4 us-gaap Proceeds From Issuance Of Warrants
ProceedsFromIssuanceOfWarrants
56100000
CY2019 us-gaap Amortization Of Financing Costs And Discounts
AmortizationOfFinancingCostsAndDiscounts
2900000
CY2021Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months Number Of Positions
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsNumberOfPositions
727
CY2021Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months
934791000
CY2021Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months Accumulated Loss
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss
4311000
CY2021Q2 ions Call Spread
CallSpread
46900000
CY2021Q2 us-gaap Payments For Hedge Financing Activities
PaymentsForHedgeFinancingActivities
136700000
CY2021Q2 us-gaap Proceeds From Issuance Of Warrants
ProceedsFromIssuanceOfWarrants
89800000
CY2019Q4 ions Call Spread
CallSpread
52600000
CY2019Q4 us-gaap Payments For Hedge Financing Activities
PaymentsForHedgeFinancingActivities
108700000
CY2021Q4 ions Long Term Obligations Noncurrent
LongTermObligationsNoncurrent
1247524000
CY2021Q4 ions Long Term Obligations Current
LongTermObligationsCurrent
3526000
CY2021Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
22058000
CY2021Q4 us-gaap Other Liabilities
OtherLiabilities
7181000
CY2021Q4 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
5429000
CY2021Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
22058000
CY2020Q4 us-gaap Valuation Allowances And Reserves Period Increase Decrease
ValuationAllowancesAndReservesPeriodIncreaseDecrease
341000000
CY2019 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense
0
CY2021Q4 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
1.59
CY2020Q4 us-gaap Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
-356008000
CY2020Q4 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
139956000
CY2020Q4 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-2.54

Files In Submission

Name View Source Status
0000874015-22-000079-index-headers.html Edgar Link pending
0000874015-22-000079-index.html Edgar Link pending
0000874015-22-000079.txt Edgar Link pending
0000874015-22-000079-xbrl.zip Edgar Link pending
exhibit10-19.htm Edgar Link pending
exhibit10-60.htm Edgar Link pending
exhibit10-83.htm Edgar Link pending
exhibit10-84.htm Edgar Link pending
exhibit21-1.htm Edgar Link pending
exhibit23-1.htm Edgar Link pending
exhibit31-1.htm Edgar Link pending
exhibit31-2.htm Edgar Link pending
exhibit32-1.htm Edgar Link pending
exhibit4-11.htm Edgar Link pending
FilingSummary.xml Edgar Link unprocessable
Financial_Report.xlsx Edgar Link pending
form10k.htm Edgar Link pending
form10k_htm.xml Edgar Link completed
image01.jpg Edgar Link pending
image02.jpg Edgar Link pending
image03.jpg Edgar Link pending
image04.jpg Edgar Link pending
image05.jpg Edgar Link pending
image06.jpg Edgar Link pending
image07.jpg Edgar Link pending
image08.jpg Edgar Link pending
image09.jpg Edgar Link pending
image10.jpg Edgar Link pending
image11.jpg Edgar Link pending
image12.jpg Edgar Link pending
image13.jpg Edgar Link pending
image14.jpg Edgar Link pending
ions-20211231.xsd Edgar Link pending
ions-20211231_cal.xml Edgar Link unprocessable
ions-20211231_def.xml Edgar Link unprocessable
ions-20211231_lab.xml Edgar Link unprocessable
ions-20211231_pre.xml Edgar Link unprocessable
MetaLinks.json Edgar Link pending
R1.htm Edgar Link pending
R10.htm Edgar Link pending
R11.htm Edgar Link pending
R12.htm Edgar Link pending
R13.htm Edgar Link pending
R14.htm Edgar Link pending
R15.htm Edgar Link pending
R16.htm Edgar Link pending
R17.htm Edgar Link pending
R18.htm Edgar Link pending
R19.htm Edgar Link pending
R2.htm Edgar Link pending
R20.htm Edgar Link pending
R21.htm Edgar Link pending
R22.htm Edgar Link pending
R23.htm Edgar Link pending
R24.htm Edgar Link pending
R25.htm Edgar Link pending
R26.htm Edgar Link pending
R27.htm Edgar Link pending
R28.htm Edgar Link pending
R29.htm Edgar Link pending
R3.htm Edgar Link pending
R30.htm Edgar Link pending
R31.htm Edgar Link pending
R32.htm Edgar Link pending
R33.htm Edgar Link pending
R34.htm Edgar Link pending
R35.htm Edgar Link pending
R36.htm Edgar Link pending
R37.htm Edgar Link pending
R38.htm Edgar Link pending
R39.htm Edgar Link pending
R4.htm Edgar Link pending
R40.htm Edgar Link pending
R41.htm Edgar Link pending
R42.htm Edgar Link pending
R43.htm Edgar Link pending
R44.htm Edgar Link pending
R45.htm Edgar Link pending
R46.htm Edgar Link pending
R47.htm Edgar Link pending
R48.htm Edgar Link pending
R49.htm Edgar Link pending
R5.htm Edgar Link pending
R50.htm Edgar Link pending
R51.htm Edgar Link pending
R52.htm Edgar Link pending
R53.htm Edgar Link pending
R54.htm Edgar Link pending
R55.htm Edgar Link pending
R56.htm Edgar Link pending
R57.htm Edgar Link pending
R58.htm Edgar Link pending
R59.htm Edgar Link pending
R6.htm Edgar Link pending
R60.htm Edgar Link pending
R61.htm Edgar Link pending
R62.htm Edgar Link pending
R63.htm Edgar Link pending
R64.htm Edgar Link pending
R65.htm Edgar Link pending
R66.htm Edgar Link pending
R67.htm Edgar Link pending
R68.htm Edgar Link pending
R69.htm Edgar Link pending
R7.htm Edgar Link pending
R70.htm Edgar Link pending
R71.htm Edgar Link pending
R72.htm Edgar Link pending
R73.htm Edgar Link pending
R74.htm Edgar Link pending
R75.htm Edgar Link pending
R76.htm Edgar Link pending
R77.htm Edgar Link pending
R78.htm Edgar Link pending
R79.htm Edgar Link pending
R8.htm Edgar Link pending
R80.htm Edgar Link pending
R81.htm Edgar Link pending
R82.htm Edgar Link pending
R83.htm Edgar Link pending
R84.htm Edgar Link pending
R85.htm Edgar Link pending
R9.htm Edgar Link pending
report.css Edgar Link pending
Show.js Edgar Link pending