$KPTI
Karyopharm Therapeutics Inc.

2024 Q1 Form 10-K Financial Statement

#000095017024022650 Filed on February 29, 2024

View on sec.gov

Income Statement

Concept 2024 Q1 2023 Q4 2023
Revenue $33.13M $33.75M $146.0M
YoY Change -14.4% 0.5% -7.03%
Cost Of Revenue $1.911M $1.486M $4.942M
YoY Change 41.45% -20.45% -5.2%
Gross Profit $31.22M $32.26M $141.1M
YoY Change -16.42% 1.73% -7.09%
Gross Profit Margin 94.23% 95.6% 96.62%
Selling, General & Admin $29.55M $30.69M $131.9M
YoY Change -17.71% -11.43% -9.3%
% of Gross Profit 94.66% 95.12% 93.47%
Research & Development $35.43M $39.38M $138.8M
YoY Change 9.54% 27.31% -6.67%
% of Gross Profit 113.49% 122.07% 98.34%
Depreciation & Amortization $85.00K $77.00K $530.0K
YoY Change -70.69% -31.86% -14.65%
% of Gross Profit 0.27% 0.24% 0.38%
Operating Expenses $66.89M $70.07M $275.6M
YoY Change -3.9% 6.84% -7.92%
Operating Profit -$33.76M -$37.81M -$129.5M
YoY Change 9.26% 11.63% -8.9%
Interest Expense $5.884M -$3.688M $23.82M
YoY Change 2.19% -18.96% -4.69%
% of Operating Profit
Other Income/Expense, Net -$3.532M -$211.0K -$13.24M
YoY Change 11.31% 1523.08% -41.74%
Pretax Income -$37.29M -$41.71M -$142.8M
YoY Change 9.45% 8.52% -13.43%
Income Tax $71.00K $130.0K $300.0K
% Of Pretax Income
Net Earnings -$37.36M -$41.84M -$143.1M
YoY Change 9.48% 8.65% -13.43%
Net Earnings / Revenue -112.79% -123.97% -97.99%
Basic Earnings Per Share -$0.32 -$1.25
Diluted Earnings Per Share -$0.32 -$0.36 -$1.25
COMMON SHARES
Basic Shares Outstanding 115.1M 114.5M 114.2M
Diluted Shares Outstanding 115.5M 114.2M

Balance Sheet

Concept 2024 Q1 2023 Q4 2023
SHORT-TERM ASSETS
Cash & Short-Term Investments $148.6M $191.4M $191.4M
YoY Change -42.94% -31.13% -31.13%
Cash & Equivalents $30.63M $52.23M $52.23M
Short-Term Investments $118.0M $139.2M $139.2M
Other Short-Term Assets $15.94M $12.47M $12.47M
YoY Change -16.69% -40.28% -40.28%
Inventory $2.769M $3.043M $3.043M
Prepaid Expenses
Receivables $31.08M $26.96M $26.96M
Other Receivables $0.00 $0.00 $0.00
Total Short-Term Assets $198.4M $233.9M $233.9M
YoY Change -37.73% -33.2% -33.2%
LONG-TERM ASSETS
Property, Plant & Equipment $719.0K $606.0K $4.882M
YoY Change -15.31% -46.8% -33.82%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets $1.638M $1.635M $1.635M
YoY Change 158.36% 158.29% 158.29%
Total Long-Term Assets $6.092M $6.517M $6.517M
YoY Change -16.08% -18.64% -18.64%
TOTAL ASSETS
Total Short-Term Assets $198.4M $233.9M $233.9M
Total Long-Term Assets $6.092M $6.517M $6.517M
Total Assets $204.5M $240.4M $240.4M
YoY Change -37.24% -32.87% -32.87%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $5.028M $3.123M $3.123M
YoY Change -44.41% 12.62% 12.62%
Accrued Expenses $54.85M $61.39M $64.70M
YoY Change 16.62% 5.1% 5.57%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due
YoY Change
Total Short-Term Liabilities $65.34M $69.48M $69.48M
YoY Change 6.15% 5.42% 5.42%
LONG-TERM LIABILITIES
Long-Term Debt $303.6M $303.4M $303.4M
YoY Change 0.19% 0.19% 0.19%
Other Long-Term Liabilities $2.582M $978.0K $3.767M
YoY Change 137.97% -83.96% -38.22%
Total Long-Term Liabilities $2.582M $978.0K $307.2M
YoY Change 137.97% -99.68% -0.57%
TOTAL LIABILITIES
Total Short-Term Liabilities $65.34M $69.48M $69.48M
Total Long-Term Liabilities $2.582M $978.0K $307.2M
Total Liabilities $373.4M $376.6M $376.6M
YoY Change 0.66% 0.48% 0.48%
SHAREHOLDERS EQUITY
Retained Earnings -$1.524B -$1.500B
YoY Change 10.62% 15.38%
Common Stock $1.356B $1.351B
YoY Change 1.7% 1.74%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity -$169.0M -$136.2M -$136.2M
YoY Change
Total Liabilities & Shareholders Equity $204.5M $240.4M $240.4M
YoY Change -37.24% -32.87% -32.87%

Cashflow Statement

Concept 2024 Q1 2023 Q4 2023
OPERATING ACTIVITIES
Net Income -$37.36M -$41.84M -$143.1M
YoY Change 9.48% 8.65% -13.43%
Depreciation, Depletion And Amortization $85.00K $77.00K $530.0K
YoY Change -70.69% -31.86% -14.65%
Cash From Operating Activities -$43.73M -$18.58M -$92.72M
YoY Change 131.23% -30.76% -38.0%
INVESTING ACTIVITIES
Capital Expenditures $195.0K $0.00 $0.00
YoY Change -100.0%
Acquisitions
YoY Change
Other Investing Activities $22.14M $26.84M $7.940M
YoY Change -168.34% -141.11% -107.62%
Cash From Investing Activities $21.94M $26.84M $7.940M
YoY Change -167.74% -141.11% -107.62%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities 264.0K 1.124M
YoY Change -99.83% -99.42%
NET CHANGE
Cash From Operating Activities -43.73M -18.58M -92.72M
Cash From Investing Activities 21.94M 26.84M 7.940M
Cash From Financing Activities 264.0K 1.124M
Net Change In Cash -21.80M 8.522M -83.69M
YoY Change -57.54% -86.62% 38.2%
FREE CASH FLOW
Cash From Operating Activities -$43.73M -$18.58M -$92.72M
Capital Expenditures $195.0K $0.00 $0.00
Free Cash Flow -$43.92M -$18.58M -$92.72M
YoY Change 132.26% -30.76% -38.05%

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CY2021 us-gaap Increase Decrease In Inventories
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CY2022 kpti Increase Decrease In Operating Lease Right Of Use Asset
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CY2021 kpti Increase Decrease In Operating Lease Right Of Use Asset
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CY2022 us-gaap Increase Decrease In Accrued Liabilities And Other Operating Liabilities
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CY2021 us-gaap Increase Decrease In Accrued Liabilities And Other Operating Liabilities
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CY2023 kpti Increase Decrease In Operating Lease Liabilities
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CY2022 kpti Increase Decrease In Operating Lease Liabilities
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CY2021 kpti Increase Decrease In Operating Lease Liabilities
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CY2021 us-gaap Net Cash Provided By Used In Operating Activities
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CY2021 us-gaap Proceeds From Sale And Maturity Of Available For Sale Securities
ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
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CY2022 us-gaap Payments To Acquire Available For Sale Securities Debt
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CY2021 us-gaap Payments To Acquire Available For Sale Securities Debt
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CY2022 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
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CY2021 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
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CY2023 us-gaap Payments To Acquire In Process Research And Development
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CY2022 us-gaap Payments To Acquire In Process Research And Development
PaymentsToAcquireInProcessResearchAndDevelopment
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CY2021 us-gaap Payments To Acquire In Process Research And Development
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CY2022 us-gaap Net Cash Provided By Used In Investing Activities
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CY2021 us-gaap Net Cash Provided By Used In Investing Activities
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ProceedsFromPaymentsForCommonStockIssuanceNet
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CY2022 kpti Proceeds From Payments For Common Stock Issuance Net
ProceedsFromPaymentsForCommonStockIssuanceNet
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CY2021 kpti Proceeds From Payments For Common Stock Issuance Net
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ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
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CY2023 kpti Proceeds From Amended Revenue Interest Agreement
ProceedsFromAmendedRevenueInterestAgreement
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CY2022 kpti Proceeds From Amended Revenue Interest Agreement
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CY2021 kpti Proceeds From Amended Revenue Interest Agreement
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CY2021 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
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CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
136885000
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InterestPaidNet
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InterestPaidNet
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CashPaidForAmountsIncludedInMeasurementOfOperatingLeaseLiabilities
3718000
CY2022 kpti Cash Paid For Amounts Included In Measurement Of Operating Lease Liabilities
CashPaidForAmountsIncludedInMeasurementOfOperatingLeaseLiabilities
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CY2021 kpti Cash Paid For Amounts Included In Measurement Of Operating Lease Liabilities
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RevenueRecognitionSalesReturn
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CY2023 us-gaap Number Of Operating Segments
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<p style="font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-weight:bold;font-size:10pt;font-family:Times New Roman;font-style:italic;min-width:fit-content;">Use of Estimates</span><span style="color:#000000;white-space:pre-wrap;font-weight:bold;font-size:10pt;font-family:Times New Roman;font-style:italic;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:6pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:10pt;font-family:Times New Roman;min-width:fit-content;">The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenues and expenses during the reporting period.</span><span style="color:#000000;white-space:pre-wrap;font-size:10pt;font-family:Times New Roman;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:10pt;font-family:Times New Roman;min-width:fit-content;">On an ongoing basis, we evaluate our estimates, including estimates related to our net product revenue, license and other revenue, clinical trial accruals, stock-based compensation expense, interest expense on our deferred royalty obligation, our embedded derivative liability, valuation allowances, and other reported amounts of expenses during the reported period. We base our estimates on historical experience and other market-specific or relevant assumptions that we believe to be reasonable under the circumstances. Although we regularly assess these estimates, actual results could differ from those estimates. Changes in estimates are recorded in the period in which they become known.</span></p>
CY2023Q4 us-gaap Allowance For Doubtful Accounts Receivable
AllowanceForDoubtfulAccountsReceivable
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CY2022Q4 us-gaap Allowance For Doubtful Accounts Receivable
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CY2023 us-gaap Allowance For Doubtful Accounts Receivable Write Offs
AllowanceForDoubtfulAccountsReceivableWriteOffs
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RevenueRecognitionSaleReturnsReserveForSaleReturns
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RevenueRecognitionProvisionForDiscountsChargeBacksFeesRebatesOtherIncentivesAndSalesReturns
21160000
CY2021 kpti Revenue Recognition Payments For Chargebacks Current Year
RevenueRecognitionPaymentsForChargebacksCurrentYear
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CY2021 kpti Revenue Recognition Payments For Fees Rebates And Other Incentives Current Year
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CY2021 kpti Revenue Recognition Credits For Discounts Charge Backs Fees Rebates Other Incentives And Sales Returns Current Year
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-21540000
CY2021Q4 kpti Revenue Recognition Discounts And Charge Backs
RevenueRecognitionDiscountsAndChargeBacks
1911000
CY2021Q4 kpti Revenue Recognition Fees Rebates And Other Incentives
RevenueRecognitionFeesRebatesAndOtherIncentives
2306000
CY2020Q4 kpti Revenue Recognition Discounts And Charge Backs
RevenueRecognitionDiscountsAndChargeBacks
2079000
CY2020Q4 kpti Revenue Recognition Fees Rebates And Other Incentives
RevenueRecognitionFeesRebatesAndOtherIncentives
2193000
CY2020Q4 kpti Revenue Recognition Sales Return
RevenueRecognitionSalesReturn
669000
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CY2021 kpti Revenue Recognition Provision For Discounts And Charge Backs
RevenueRecognitionProvisionForDiscountsAndChargeBacks
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CY2021 kpti Revenue Recognition Provision For Fees Rebates And Other Incentives
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CY2022 kpti Revenue Recognition Provision For Discounts And Charge Backs
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CY2022 kpti Revenue Recognition Provision For Fees Rebates And Other Incentives
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CY2022 kpti Revenue Recognition Sale Returns Reserve For Sale Returns
RevenueRecognitionSaleReturnsReserveForSaleReturns
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CY2022 kpti Revenue Recognition Payments For Chargebacks Current Year
RevenueRecognitionPaymentsForChargebacksCurrentYear
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CY2022 kpti Revenue Recognition Payments For Fees Rebates And Other Incentives Current Year
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CY2022 kpti Revenue Recognition Payments For Discounts Charge Backs Fees Rebates Other Incentives And Sales Returns
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CY2022 kpti Revenue Recognition Credits For Discounts Charge Backs Fees Rebates Other Incentives And Sales Returns Current Year
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CY2022Q4 kpti Revenue Recognition Discounts And Charge Backs
RevenueRecognitionDiscountsAndChargeBacks
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CY2022Q4 kpti Revenue Recognition Fees Rebates And Other Incentives
RevenueRecognitionFeesRebatesAndOtherIncentives
3734000
CY2022Q4 kpti Revenue Recognition Sales Return
RevenueRecognitionSalesReturn
542000
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7141000
CY2023 kpti Revenue Recognition Provision For Discounts And Charge Backs
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21106000
CY2023 kpti Revenue Recognition Provision For Fees Rebates And Other Incentives
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CY2023 kpti Revenue Recognition Sale Returns Reserve For Sale Returns
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CY2023 kpti Revenue Recognition Provision For Discounts Charge Backs Fees Rebates Other Incentives And Sales Returns
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32131000
CY2023 kpti Revenue Recognition Payments For Chargebacks Current Year
RevenueRecognitionPaymentsForChargebacksCurrentYear
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CY2023 kpti Revenue Recognition Payments For Fees Rebates And Other Incentives Current Year
RevenueRecognitionPaymentsForFeesRebatesAndOtherIncentivesCurrentYear
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CY2023 kpti Revenue Recognition Payments For Discounts Charge Backs Fees Rebates Other Incentives And Sales Returns
RevenueRecognitionPaymentsForDiscountsChargeBacksFeesRebatesOtherIncentivesAndSalesReturns
-224000
CY2023 kpti Revenue Recognition Credits For Discounts Charge Backs Fees Rebates Other Incentives And Sales Returns Current Year
RevenueRecognitionCreditsForDiscountsChargeBacksFeesRebatesOtherIncentivesAndSalesReturnsCurrentYear
-31768000
CY2023Q4 kpti Revenue Recognition Discounts And Charge Backs
RevenueRecognitionDiscountsAndChargeBacks
2516000
CY2023Q4 kpti Revenue Recognition Fees Rebates And Other Incentives
RevenueRecognitionFeesRebatesAndOtherIncentives
4670000
CY2023Q4 kpti Revenue Recognition Sales Return
RevenueRecognitionSalesReturn
318000
CY2023Q4 kpti Revenue Recognition Discounts Charge Backs Fees Rebates Other Incentives And Sales Returns
RevenueRecognitionDiscountsChargeBacksFeesRebatesOtherIncentivesAndSalesReturns
7504000
CY2023Q4 us-gaap Inventory Raw Materials And Supplies
InventoryRawMaterialsAndSupplies
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CY2022Q4 us-gaap Inventory Raw Materials And Supplies
InventoryRawMaterialsAndSupplies
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CY2023Q4 us-gaap Inventory Work In Process
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CY2022Q4 us-gaap Inventory Work In Process
InventoryWorkInProcess
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CY2023Q4 us-gaap Inventory Finished Goods
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CY2022Q4 us-gaap Inventory Finished Goods
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CY2023Q4 us-gaap Inventory Net
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CY2022Q4 us-gaap Inventory Net
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4224000
CY2021Q3 kpti Additional Common Share Issued On Assets Acquired
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75000
CY2023 kpti Contract With Customer License And Other Revenue
ContractWithCustomerLicenseAndOtherRevenue
34022000
CY2022 kpti Contract With Customer License And Other Revenue
ContractWithCustomerLicenseAndOtherRevenue
36629000
CY2021 kpti Contract With Customer License And Other Revenue
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CY2021 us-gaap Other Income
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CY2022Q4 us-gaap Assets Fair Value Disclosure
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CY2022Q4 us-gaap Embedded Derivative Fair Value Of Embedded Derivative Liability
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139281000
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CY2023 us-gaap Available For Sale Debt Securities Gross Unrealized Loss
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165000
CY2023Q4 us-gaap Available For Sale Securities Debt Securities
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CY2022Q4 us-gaap Available For Sale Debt Securities Amortized Cost Basis
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CY2022 us-gaap Available For Sale Debt Securities Gross Unrealized Gain
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4000
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348000
CY2022Q4 us-gaap Available For Sale Securities Debt Securities
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142779000
CY2023Q4 kpti Available For Sale Securities In Unrealized Loss Positions Qualitative Disclosure Number Of Positions Less Than One Years
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41
CY2022Q4 kpti Available For Sale Securities In Unrealized Loss Positions Qualitative Disclosure Number Of Positions Less Than One Years
AvailableForSaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositionsLessThanOneYears
60
CY2023Q4 kpti Available For Sale Securities Accumulated Gross Unrealized Loss Before Tax Other Than Temporary Impairments
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0
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0
CY2023Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months
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84465000
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DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss
152000
CY2023Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position12 Months Or Longer
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger
6276000
CY2023Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position12 Months Or Longer Accumulated Loss
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss
13000
CY2023Q4 us-gaap Debt Securities Available For Sale Unrealized Loss Position
DebtSecuritiesAvailableForSaleUnrealizedLossPosition
90741000
CY2023Q4 us-gaap Debt Securities Available For Sale Unrealized Loss Position Accumulated Loss
DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss
165000
CY2022Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months
129131000
CY2022Q4 us-gaap Debt Securities Available For Sale Continuous Unrealized Loss Position Less Than12 Months Accumulated Loss
DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss
348000
CY2022Q4 us-gaap Debt Securities Available For Sale Unrealized Loss Position
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129131000
CY2022Q4 us-gaap Debt Securities Available For Sale Unrealized Loss Position Accumulated Loss
DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss
348000
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CY2023 us-gaap Allocated Share Based Compensation Expense
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21709000
CY2022 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
35399000
CY2021 us-gaap Allocated Share Based Compensation Expense
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29783000
CY2023 kpti Debt Instrument Convertible Threshold Measurement Period Description
DebtInstrumentConvertibleThresholdMeasurementPeriodDescription
during the five-business day period immediately after any five consecutive trading day period
CY2023 us-gaap Debt Instrument Convertible Threshold Consecutive Trading Days1
DebtInstrumentConvertibleThresholdConsecutiveTradingDays1
5
CY2023 kpti Principal Amount Of Notes Used In Conversion Rate
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1000
CY2023 kpti Debt Instrument Convertible Threshold Maximum Percentage Of Product Of Last Reported Sale Price Of Common Stock
DebtInstrumentConvertibleThresholdMaximumPercentageOfProductOfLastReportedSalePriceOfCommonStock
0.98
CY2023 us-gaap Operating Lease Expense
OperatingLeaseExpense
2800000
CY2022 us-gaap Operating Lease Expense
OperatingLeaseExpense
2800000
CY2021 us-gaap Operating Lease Expense
OperatingLeaseExpense
2800000
CY2023Q4 us-gaap Lessee Operating Lease Liability Payments Due Next Twelve Months
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3817000
CY2023Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Two
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2918000
CY2023Q4 us-gaap Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
6735000
CY2023Q4 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
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638000
CY2023Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
6097000
CY2023Q4 us-gaap Lessee Operating Lease Term Of Contract
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P1Y9M18D
CY2023Q4 us-gaap Lessee Operating Lease Discount Rate
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0.11
CY2023Q4 kpti Legal Claims Outstanding
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0
CY2023Q4 kpti Accrued Research And Development Costs Current
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19601000
CY2022Q4 kpti Accrued Research And Development Costs Current
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15600000
CY2023Q4 us-gaap Employee Related Liabilities Current
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16510000
CY2022Q4 us-gaap Employee Related Liabilities Current
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19625000
CY2023Q4 us-gaap Interest Payable Current
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13454000
CY2022Q4 us-gaap Interest Payable Current
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11673000
CY2023Q4 kpti Product Rebates Discounts Reserves And Royalties Current
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4706000
CY2022Q4 kpti Product Rebates Discounts Reserves And Royalties Current
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5110000
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61394000
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58415000
CY2023Q4 us-gaap Property Plant And Equipment Gross
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7171000
CY2022Q4 us-gaap Property Plant And Equipment Gross
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7784000
CY2023Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
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6565000
CY2022Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
6645000
CY2023Q4 us-gaap Property Plant And Equipment Net
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606000
CY2022Q4 us-gaap Property Plant And Equipment Net
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1139000
CY2023 us-gaap Defined Contribution Plan Employer Matching Contribution Percent
DefinedContributionPlanEmployerMatchingContributionPercent
0.04
CY2023 us-gaap Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
3700000
CY2022 us-gaap Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
3100000
CY2021 us-gaap Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
2900000
CY2023 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
300000
CY2022 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
400000
CY2021 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
300000
CY2023 us-gaap Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
0
CY2022 us-gaap Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
0
CY2021 us-gaap Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
0
CY2023 us-gaap Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
247000
CY2022 us-gaap Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
892000
CY2021 us-gaap Income Loss From Continuing Operations Before Income Taxes Foreign
IncomeLossFromContinuingOperationsBeforeIncomeTaxesForeign
-30052000
CY2023 us-gaap Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
-143023000
CY2022 us-gaap Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
-165814000
CY2021 us-gaap Income Loss From Continuing Operations Before Income Taxes Domestic
IncomeLossFromContinuingOperationsBeforeIncomeTaxesDomestic
-93768000
CY2023 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-142776000
CY2022 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-164922000
CY2021 us-gaap Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
-123820000
CY2023Q4 kpti Deferred Tax Assets Operating Loss Carryforwards Domestic And State And Local
DeferredTaxAssetsOperatingLossCarryforwardsDomesticAndStateAndLocal
198158000
CY2022Q4 kpti Deferred Tax Assets Operating Loss Carryforwards Domestic And State And Local
DeferredTaxAssetsOperatingLossCarryforwardsDomesticAndStateAndLocal
189629000
CY2023Q4 us-gaap Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
108682000
CY2022Q4 us-gaap Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
100436000
CY2023Q4 kpti Deferred Tax Assets Fixed Assets And Intangibles
DeferredTaxAssetsFixedAssetsAndIntangibles
25028000
CY2022Q4 kpti Deferred Tax Assets Fixed Assets And Intangibles
DeferredTaxAssetsFixedAssetsAndIntangibles
27312000
CY2023Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
8500000
CY2022Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
13818000
CY2023Q4 kpti Deferred Tax Assets Tax Deferred Expense Reserves And Accruals And Other Temporary Differences
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAndOtherTemporaryDifferences
6380000
CY2022Q4 kpti Deferred Tax Assets Tax Deferred Expense Reserves And Accruals And Other Temporary Differences
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsAndOtherTemporaryDifferences
6613000
CY2023Q4 kpti Deferred Tax Assets Interest Expense
DeferredTaxAssetsInterestExpense
6894000
CY2022Q4 kpti Deferred Tax Assets Interest Expense
DeferredTaxAssetsInterestExpense
9236000
CY2023Q4 kpti Deferred Tax Assets Lease Liability
DeferredTaxAssetsLeaseLiability
1461000
CY2022Q4 kpti Deferred Tax Assets Lease Liability
DeferredTaxAssetsLeaseLiability
2193000
CY2023Q4 kpti Deferred Tax Assets Deferred Royalty Obligations
DeferredTaxAssetsDeferredRoyaltyObligations
8310000
CY2022Q4 kpti Deferred Tax Assets Deferred Royalty Obligations
DeferredTaxAssetsDeferredRoyaltyObligations
1805000
CY2023Q4 us-gaap Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
47986000
CY2022Q4 us-gaap Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
27748000
CY2023Q4 kpti Deferred Tax Assets Royalty Embaded Derivatives
DeferredTaxAssetsRoyaltyEmbadedDerivatives
671000
CY2022Q4 kpti Deferred Tax Assets Royalty Embaded Derivatives
DeferredTaxAssetsRoyaltyEmbadedDerivatives
679000
CY2023Q4 kpti Deferred Tax Assets Unicap
DeferredTaxAssetsUnicap
800000
CY2022Q4 kpti Deferred Tax Assets Unicap
DeferredTaxAssetsUnicap
1214000
CY2023Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
411838000
CY2022Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
379166000
CY2023Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
1032000
CY2022Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
1517000
CY2023Q4 kpti Deferred Tax Liabilities Convertible Debt Amortization
DeferredTaxLiabilitiesConvertibleDebtAmortization
7000
CY2022Q4 kpti Deferred Tax Liabilities Convertible Debt Amortization
DeferredTaxLiabilitiesConvertibleDebtAmortization
5000
CY2023Q4 kpti Deferred Tax Liabilities Right Of Use Asset
DeferredTaxLiabilitiesRightOfUseAsset
1025000
CY2022Q4 kpti Deferred Tax Liabilities Right Of Use Asset
DeferredTaxLiabilitiesRightOfUseAsset
-1512000
CY2023Q4 us-gaap Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
1032000
CY2022Q4 us-gaap Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
1517000
CY2023Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
0
CY2022Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
0
CY2023 kpti Tax Cuts And Jobs Act Capitalized Research And Development Costs
TaxCutsAndJobsActCapitalizedResearchAndDevelopmentCosts
135900000
CY2022 kpti Tax Cuts And Jobs Act Capitalized Research And Development Costs
TaxCutsAndJobsActCapitalizedResearchAndDevelopmentCosts
131400000
CY2023 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense
0
CY2022 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense
0
CY2021 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Expense
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestExpense
0
CY2023 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
32700000
CY2023 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
CY2022 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
CY2021 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
CY2023 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.04
CY2022 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.04
CY2021 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.008
CY2023 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense
EffectiveIncomeTaxRateReconciliationNondeductibleExpense
-0.01
CY2022 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense
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-0.033
CY2021 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense
EffectiveIncomeTaxRateReconciliationNondeductibleExpense
-0.027
CY2023 us-gaap Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
0.073
CY2022 us-gaap Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
0.063
CY2021 us-gaap Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
0.113
CY2023 us-gaap Effective Income Tax Rate Reconciliation Foreign Income Tax Rate Differential
EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential
0
CY2022 us-gaap Effective Income Tax Rate Reconciliation Foreign Income Tax Rate Differential
EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential
0
CY2021 us-gaap Effective Income Tax Rate Reconciliation Foreign Income Tax Rate Differential
EffectiveIncomeTaxRateReconciliationForeignIncomeTaxRateDifferential
-0.052
CY2023 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
-0.229
CY2022 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
-0.293
CY2021 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
-0.354
CY2023 kpti Effective Income Tax Rate Reconciliation At Migrated Intellectual Property Income Tax Rate Percent
EffectiveIncomeTaxRateReconciliationAtMigratedIntellectualPropertyIncomeTaxRatePercent
0
CY2022 kpti Effective Income Tax Rate Reconciliation At Migrated Intellectual Property Income Tax Rate Percent
EffectiveIncomeTaxRateReconciliationAtMigratedIntellectualPropertyIncomeTaxRatePercent
0
CY2021 kpti Effective Income Tax Rate Reconciliation At Migrated Intellectual Property Income Tax Rate Percent
EffectiveIncomeTaxRateReconciliationAtMigratedIntellectualPropertyIncomeTaxRatePercent
0.139
CY2023 us-gaap Effective Income Tax Rate Reconciliation Share Based Compensation Excess Tax Benefit Percent
EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitPercent
-0.05
CY2022 us-gaap Effective Income Tax Rate Reconciliation Share Based Compensation Excess Tax Benefit Percent
EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitPercent
-0.02
CY2021 us-gaap Effective Income Tax Rate Reconciliation Share Based Compensation Excess Tax Benefit Percent
EffectiveIncomeTaxRateReconciliationShareBasedCompensationExcessTaxBenefitPercent
-0.043
CY2023 us-gaap Effective Income Tax Rate Reconciliation Prior Year Income Taxes
EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes
-0.028
CY2022 us-gaap Effective Income Tax Rate Reconciliation Prior Year Income Taxes
EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes
0
CY2021 us-gaap Effective Income Tax Rate Reconciliation Prior Year Income Taxes
EffectiveIncomeTaxRateReconciliationPriorYearIncomeTaxes
-0.005
CY2023 us-gaap Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
-0.008
CY2022 us-gaap Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
0.031
CY2021 us-gaap Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
0.009
CY2023 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.002
CY2022 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.002
CY2021 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
-0.002
CY2023 kpti Fair Market Value Of The Rights Upfront Payment
FairMarketValueOfTheRightsUpfrontPayment
75000000
CY2023 kpti Operating Loss And Tax Credit Carryforwards Limitations Period Over Which Cumulative Changes In Ownership Interest Of Significant Shareholders Considered
OperatingLossAndTaxCreditCarryforwardsLimitationsPeriodOverWhichCumulativeChangesInOwnershipInterestOfSignificantShareholdersConsidered
P3Y
CY2023 kpti Operating Loss And Tax Credit Carryforwards Limitations Threshold Percentage Of Cumulative Changes In Ownership Interest Of Significant Shareholders Considered
OperatingLossAndTaxCreditCarryforwardsLimitationsThresholdPercentageOfCumulativeChangesInOwnershipInterestOfSignificantShareholdersConsidered
50
CY2023Q4 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued
0
CY2022Q4 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued
0
CY2021Q4 us-gaap Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued
0

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