2022 Q1 Form 10-Q Financial Statement

#000143774922011142 Filed on May 05, 2022

View on sec.gov

Income Statement

Concept 2022 Q1 2021 Q1
Revenue $45.74M $98.17M
YoY Change -53.41% 91.67%
Cost Of Revenue $10.84M $29.56M
YoY Change -63.31% 225.52%
Gross Profit $34.89M $68.61M
YoY Change -49.15% 62.82%
Gross Profit Margin 76.29% 69.89%
Selling, General & Admin $20.40M $28.24M
YoY Change -27.75% -8.72%
% of Gross Profit 58.47% 41.16%
Research & Development $15.24M $20.23M
YoY Change -24.67% -20.53%
% of Gross Profit 43.67% 29.48%
Depreciation & Amortization $200.0K $200.0K
YoY Change 0.0% 0.0%
% of Gross Profit 0.57% 0.29%
Operating Expenses $35.64M $48.47M
YoY Change -26.47% -25.97%
Operating Profit -$747.0K $20.15M
YoY Change -103.71% -186.36%
Interest Expense $2.664M $3.450M
YoY Change -22.78% 12.45%
% of Operating Profit 17.12%
Other Income/Expense, Net -$2.619M -$3.580M
YoY Change -26.84% 33.48%
Pretax Income -$3.366M $16.57M
YoY Change -120.32% -197.83%
Income Tax $37.00K $38.00K
% Of Pretax Income 0.23%
Net Earnings -$3.403M $16.53M
YoY Change -120.59% -197.61%
Net Earnings / Revenue -7.44% 16.84%
Basic Earnings Per Share -$0.08 $0.41
Diluted Earnings Per Share -$0.08 $0.40
COMMON SHARES
Basic Shares Outstanding 42.21M 40.26M
Diluted Shares Outstanding 42.21M 40.90M

Balance Sheet

Concept 2022 Q1 2021 Q1
SHORT-TERM ASSETS
Cash & Short-Term Investments $73.91M $109.1M
YoY Change -32.26% 8.45%
Cash & Equivalents $63.91M $95.70M
Short-Term Investments $9.994M $13.40M
Other Short-Term Assets $631.0K $373.0K
YoY Change 69.17% -98.4%
Inventory $7.277M $7.700M
Prepaid Expenses $8.716M
Receivables $27.04M $21.80M
Other Receivables $5.138M $4.400M
Total Short-Term Assets $117.6M $163.8M
YoY Change -28.22% 3.21%
LONG-TERM ASSETS
Property, Plant & Equipment $1.591M $2.283M
YoY Change -30.31% -26.0%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets $4.030M $4.600M
YoY Change -12.39% -26.98%
Total Long-Term Assets $83.12M $94.86M
YoY Change -12.38% 42.0%
TOTAL ASSETS
Total Short-Term Assets $117.6M $163.8M
Total Long-Term Assets $83.12M $94.86M
Total Assets $200.7M $258.7M
YoY Change -22.41% 14.7%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $7.412M $10.65M
YoY Change -30.43% -38.42%
Accrued Expenses $61.84M $79.28M
YoY Change -22.01% 14.14%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00
YoY Change
Long-Term Debt Due $22.86M
YoY Change
Total Short-Term Liabilities $74.79M $140.4M
YoY Change -46.73% 55.19%
LONG-TERM LIABILITIES
Long-Term Debt $97.38M $76.35M
YoY Change 27.55% -20.31%
Other Long-Term Liabilities $21.37M $25.50M
YoY Change -16.2% -14.72%
Total Long-Term Liabilities $97.38M $76.35M
YoY Change 27.55% -39.26%
TOTAL LIABILITIES
Total Short-Term Liabilities $74.79M $140.4M
Total Long-Term Liabilities $97.38M $76.35M
Total Liabilities $193.5M $242.2M
YoY Change -20.1% 12.06%
SHAREHOLDERS EQUITY
Retained Earnings -$1.370B
YoY Change
Common Stock $1.377B $1.338B
YoY Change 2.97% 2.58%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $7.145M $16.34M
YoY Change
Total Liabilities & Shareholders Equity $200.7M $258.7M
YoY Change -22.43% 14.71%

Cashflow Statement

Concept 2022 Q1 2021 Q1
OPERATING ACTIVITIES
Net Income -$3.403M $16.53M
YoY Change -120.59% -197.61%
Depreciation, Depletion And Amortization $200.0K $200.0K
YoY Change 0.0% 0.0%
Cash From Operating Activities -$26.90M $15.66M
YoY Change -271.76% -235.71%
INVESTING ACTIVITIES
Capital Expenditures
YoY Change
Acquisitions
YoY Change
Other Investing Activities $8.982M -$5.300M
YoY Change -269.47% -115.42%
Cash From Investing Activities $8.982M -$5.301M
YoY Change -269.44% -115.42%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities $9.845M $0.00
YoY Change
NET CHANGE
Cash From Operating Activities -$26.90M $15.66M
Cash From Investing Activities $8.982M -$5.301M
Cash From Financing Activities $9.845M $0.00
Net Change In Cash -$8.068M $10.36M
YoY Change -177.88% -54.64%
FREE CASH FLOW
Cash From Operating Activities -$26.90M $15.66M
Capital Expenditures
Free Cash Flow
YoY Change

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10360000 USD
CY2021Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
75292000 USD
CY2020Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
97454000 USD
CY2022Q1 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
67224000 USD
CY2021Q1 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
107814000 USD
CY2022Q1 us-gaap Noncash Or Part Noncash Acquisition Intangible Assets Acquired1
NoncashOrPartNoncashAcquisitionIntangibleAssetsAcquired1
0 USD
CY2021Q1 us-gaap Noncash Or Part Noncash Acquisition Intangible Assets Acquired1
NoncashOrPartNoncashAcquisitionIntangibleAssetsAcquired1
20000000 USD
CY2022Q1 us-gaap Interest Paid Net
InterestPaidNet
2375000 USD
CY2021Q1 us-gaap Interest Paid Net
InterestPaidNet
2250000 USD
CY2022Q1 us-gaap Income Taxes Paid
IncomeTaxesPaid
0 USD
CY2021Q1 us-gaap Income Taxes Paid
IncomeTaxesPaid
12000 USD
CY2022Q1 us-gaap Net Income Loss
NetIncomeLoss
-3400000 USD
CY2022Q1 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-26900000 USD
CY2022Q1 pbyi Cash Cash Equivalents And Marketable Securities
CashCashEquivalentsAndMarketableSecurities
73900000 USD
CY2022Q1 us-gaap Use Of Estimates
UseOfEstimates
<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"/> <p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: left; text-indent: 0pt;"><b>Use of Estimates: </b></p> <p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"> </p> <p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-indent: 27pt; text-align: left;">The preparation of consolidated financial statements in conformity with US GAAP, requires management to make estimates and assumptions that affect reported amounts of assets and liabilities, and disclosure of contingent assets and liabilities at the date of the balance sheet, and reported amounts of revenues and expenses for the period presented. Accordingly, actual results could differ from those estimates.</p> <p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"> </p> <p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-indent: 27pt; text-align: left;">Significant estimates include estimates for variable consideration for which reserves were established. These estimates are included in the calculation of net revenues and include trade discounts and allowances, product returns, provider chargebacks and discounts, government rebates, payor rebates, and other incentives, such as voluntary patient assistance, and other allowances that are offered within contracts between the Company and its customers, payors, and other indirect customers relating to the Company’s sale of its products.</p>
CY2022Q1 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
8726907000
CY2021Q1 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
8818465000
CY2022Q1 us-gaap Net Income Loss
NetIncomeLoss
-3403000 USD
CY2021Q1 us-gaap Net Income Loss
NetIncomeLoss
16528000 USD
CY2022Q1 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
42208000
CY2021Q1 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
40261000
CY2022Q1 us-gaap Weighted Average Number Diluted Shares Outstanding Adjustment
WeightedAverageNumberDilutedSharesOutstandingAdjustment
0
CY2021Q1 us-gaap Weighted Average Number Diluted Shares Outstanding Adjustment
WeightedAverageNumberDilutedSharesOutstandingAdjustment
634000
CY2022Q1 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
42208000
CY2021Q1 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
40895000
CY2022Q1 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.08
CY2021Q1 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
0.41
CY2022Q1 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.08
CY2021Q1 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
0.40
CY2022Q1 pbyi Sublease Agreement Potential Milestone Payments
SubleaseAgreementPotentialMilestonePayments
579800000 USD
CY2022Q1 us-gaap Restricted Cash
RestrictedCash
3300000 USD
CY2021Q4 us-gaap Restricted Cash
RestrictedCash
12200000 USD
CY2021Q4 us-gaap Inventory Finished Goods Net Of Reserves
InventoryFinishedGoodsNetOfReserves
1155000 USD
CY2022Q1 us-gaap Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
45858000 USD
CY2022Q1 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
1000 USD
CY2022Q1 pbyi Cash Cash Equivalents And Shortterm Investments Fair Value
CashCashEquivalentsAndShorttermInvestmentsFairValue
45857000 USD
CY2021Q4 us-gaap Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
69849000 USD
CY2021Q4 us-gaap Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
2000 USD
CY2021Q4 pbyi Cash Cash Equivalents And Shortterm Investments Fair Value
CashCashEquivalentsAndShorttermInvestmentsFairValue
69847000 USD
CY2022Q1 us-gaap Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
<p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"/><p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"/> <p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-align: left; text-indent: 0pt;"><b>Concentration of Risk: </b></p> <p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"> </p> <p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-indent: 27pt; text-align: left;">Financial instruments, which potentially subject the Company to concentrations of credit risk, principally consist of cash and cash equivalents, marketable securities, and accounts receivable, net. The Company’s cash and cash equivalents and restricted cash in excess of the Federal Deposit Insurance Corporation and the Securities Investor Protection Corporation insured limits at <em style="font: inherit;"> March 31, 2022</em> were approximately $67.0 million. The Company does <em style="font: inherit;">not</em> believe it is exposed to any significant credit risk due to the quality nature of the financial instruments in which the money is held. Pursuant to the Company’s internal investment policy, investments must be rated A-<em style="font: inherit;">1/P</em>-<em style="font: inherit;">1</em> or better by Standard and Poor’s Rating Service and Moody’s Investors Service at the time of purchase.</p> <p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"> </p> <p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-indent: 27pt; text-align: left;">The Company sells its products in the United States primarily through specialty pharmacies and specialty distributors. Therefore, wholesale distributors and large pharmacy chains account for a large portion of its accounts receivables, net and product revenues, net. The creditworthiness of its customers is continuously monitored, and the Company has internal policies regarding customer credit limits. The Company estimates an allowance for doubtful accounts primarily based on the credit worthiness of its customers, historical payment patterns, aging of receivable balances and general economic conditions. </p> <p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"> </p> <p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-indent: 27pt; text-align: left;">The Company’s success depends on its ability to successfully commercialize NERLYNX. The Company currently has a single product and limited commercial sales experience, which makes it difficult to evaluate its current business, predict its future prospects and forecast financial performance and growth. The Company has invested a significant portion of its efforts and financial resources in the development and commercialization of the lead product, NERLYNX, and expects NERLYNX to constitute the vast majority of product revenue for the foreseeable future.</p> <p style="font-family:'Times New Roman';font-size:10pt;font-variant:normal;margin:0pt;"> </p> <p style="font-family: &quot;Times New Roman&quot;; font-size: 10pt; font-variant: normal; margin: 0pt; text-indent: 27pt; text-align: left;">The Company relies exclusively on <em style="font: inherit;">third</em> parties to formulate and manufacture NERLYNX and its drug candidates. The commercialization of NERLYNX and any other drug candidates, if approved, could be stopped, delayed or made less profitable if those <em style="font: inherit;">third</em> parties fail to provide sufficient quantities of product or fail to do so at acceptable quality levels or prices. The Company has <em style="font: inherit;">no</em> experience in drug formulation or manufacturing and does <em style="font: inherit;">not</em> intend to establish its own manufacturing facilities. The Company lacks the resources and expertise to formulate or manufacture NERLYNX and other drug candidates. While the drug candidates were being developed by Pfizer, both the drug substance and drug product were manufactured by <em style="font: inherit;">third</em>-party contractors. The Company is using the same <em style="font: inherit;">third</em>-party contractors to manufacture, supply, store and distribute drug supplies for clinical trials and the commercialization of NERLYNX. If the Company is unable to continue its relationships with <em style="font: inherit;">one</em> or more of these <em style="font: inherit;">third</em>-party contractors, it could experience delays in the development or commercialization efforts as it locates and qualifies new manufacturers. The Company intends to rely on <em style="font: inherit;">one</em> or more <em style="font: inherit;">third</em>-party contractors to manufacture the commercial supply of drugs.</p>
CY2022Q1 pbyi Cash And Cash Equivalents And Restricted Cash In Excess Of Insured Limits
CashAndCashEquivalentsAndRestrictedCashInExcessOfInsuredLimits
67000000.0 USD
CY2022Q1 us-gaap Inventory Raw Materials Net Of Reserves
InventoryRawMaterialsNetOfReserves
4041000 USD
CY2021Q4 us-gaap Inventory Raw Materials Net Of Reserves
InventoryRawMaterialsNetOfReserves
4569000 USD
CY2022Q1 us-gaap Inventory Work In Process Net Of Reserves
InventoryWorkInProcessNetOfReserves
1607000 USD
CY2021Q4 us-gaap Inventory Work In Process Net Of Reserves
InventoryWorkInProcessNetOfReserves
1385000 USD
CY2022Q1 us-gaap Inventory Finished Goods Net Of Reserves
InventoryFinishedGoodsNetOfReserves
1629000 USD
CY2022Q1 us-gaap Inventory Net
InventoryNet
7277000 USD
CY2021Q4 us-gaap Inventory Net
InventoryNet
7109000 USD
CY2022Q1 pbyi Trade Accounts Receivable Net Excluding License Revenue Receivable
TradeAccountsReceivableNetExcludingLicenseRevenueReceivable
21901000 USD
CY2021Q4 pbyi Trade Accounts Receivable Net Excluding License Revenue Receivable
TradeAccountsReceivableNetExcludingLicenseRevenueReceivable
29646000 USD
CY2022Q1 pbyi License Revenue Receivable
LicenseRevenueReceivable
0 USD
CY2021Q4 pbyi License Revenue Receivable
LicenseRevenueReceivable
0 USD
CY2022Q1 pbyi Royalty Revenue Receivable
RoyaltyRevenueReceivable
5138000 USD
CY2021Q4 pbyi Royalty Revenue Receivable
RoyaltyRevenueReceivable
2880000 USD
CY2022Q1 pbyi Average Incremental Borrowing Rate
AverageIncrementalBorrowingRate
0.109 pure
CY2022Q1 us-gaap Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
2000000.0 USD
CY2022Q1 us-gaap Finite Lived Intangible Assets Amortization Expense Remainder Of Fiscal Year
FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear
6000000.0 USD
CY2022Q1 us-gaap Finite Lived Intangible Assets Amortization Expense Next Twelve Months
FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths
8000000.0 USD
CY2022Q1 pbyi Finitelived Intangible Asset Expected Amortization Year Eight
FinitelivedIntangibleAssetExpectedAmortizationYearEight
2000000.0 USD
CY2022Q1 us-gaap Accounts Receivable Gross
AccountsReceivableGross
27039000 USD
CY2021Q4 us-gaap Accounts Receivable Gross
AccountsReceivableGross
32526000 USD
CY2022Q1 us-gaap Provision For Doubtful Accounts
ProvisionForDoubtfulAccounts
0 USD
CY2021Q4 pbyi Prepaid Cro Services Noncurrent
PrepaidCROServicesNoncurrent
166000 USD
CY2022Q1 pbyi Prepaid Other Clinical Development Expense Noncurrent
PrepaidOtherClinicalDevelopmentExpenseNoncurrent
312000 USD
CY2021Q4 pbyi Prepaid Other Clinical Development Expense Noncurrent
PrepaidOtherClinicalDevelopmentExpenseNoncurrent
577000 USD
CY2022Q1 us-gaap Prepaid Expense Other Noncurrent
PrepaidExpenseOtherNoncurrent
247000 USD
CY2021Q4 us-gaap Prepaid Expense Other Noncurrent
PrepaidExpenseOtherNoncurrent
611000 USD
CY2022Q1 us-gaap Prepaid Expense And Other Assets Noncurrent
PrepaidExpenseAndOtherAssetsNoncurrent
719000 USD
CY2021Q4 us-gaap Prepaid Expense And Other Assets Noncurrent
PrepaidExpenseAndOtherAssetsNoncurrent
1354000 USD
CY2022Q1 us-gaap Prepaid Expense And Other Assets
PrepaidExpenseAndOtherAssets
9435000 USD
CY2021Q4 us-gaap Prepaid Expense And Other Assets
PrepaidExpenseAndOtherAssets
10338000 USD
CY2022Q1 us-gaap Operating Lease Expense
OperatingLeaseExpense
1300000 USD
CY2021Q1 us-gaap Operating Lease Expense
OperatingLeaseExpense
1200000 USD
CY2022Q1 pbyi Prepaid Cro Services Current
PrepaidCROServicesCurrent
269000 USD
CY2021Q4 pbyi Prepaid Cro Services Current
PrepaidCROServicesCurrent
340000 USD
CY2022Q1 pbyi Prepaid Other Clinical Development Current
PrepaidOtherClinicalDevelopmentCurrent
2714000 USD
CY2021Q4 pbyi Prepaid Other Clinical Development Current
PrepaidOtherClinicalDevelopmentCurrent
2933000 USD
CY2022Q1 us-gaap Prepaid Insurance
PrepaidInsurance
2423000 USD
CY2021Q4 us-gaap Prepaid Insurance
PrepaidInsurance
3178000 USD
CY2022Q1 pbyi Prepaid Professional Fess Current
PrepaidProfessionalFessCurrent
890000 USD
CY2021Q4 pbyi Prepaid Professional Fess Current
PrepaidProfessionalFessCurrent
398000 USD
CY2022Q1 us-gaap Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
2420000 USD
CY2021Q4 us-gaap Other Prepaid Expense Current
OtherPrepaidExpenseCurrent
2135000 USD
CY2022Q1 us-gaap Prepaid Expense Current
PrepaidExpenseCurrent
8716000 USD
CY2021Q4 us-gaap Prepaid Expense Current
PrepaidExpenseCurrent
8984000 USD
CY2022Q1 pbyi Prepaid Cro Services Noncurrent
PrepaidCROServicesNoncurrent
160000 USD
CY2022Q1 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
8572000 USD
CY2022Q1 us-gaap Operating Lease Payments
OperatingLeasePayments
1447000 USD
CY2022Q1 us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
0 USD
CY2022Q1 us-gaap Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
P4Y
CY2022Q1 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.109 pure
CY2022Q1 us-gaap Lessee Operating Lease Liability Payments Remainder Of Fiscal Year
LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear
4131000 USD
CY2022Q1 us-gaap Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
5631000 USD
CY2022Q1 us-gaap Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
5805000 USD
CY2022Q1 us-gaap Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
5983000 USD
CY2022Q1 us-gaap Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
1508000 USD
CY2022Q1 us-gaap Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
23058000 USD
CY2022Q1 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
4348000 USD
CY2022Q1 us-gaap Operating Lease Liability
OperatingLeaseLiability
18710000 USD
CY2022Q1 us-gaap Sublease Income
SubleaseIncome
100000 USD
CY2022Q1 us-gaap Lessor Operating Lease Payments To Be Received Remainder Of Fiscal Year
LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear
362000 USD
CY2022Q1 us-gaap Lessor Operating Lease Payments To Be Received Next Twelve Months
LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths
495000 USD
CY2022Q1 us-gaap Lessor Operating Lease Payments To Be Received Two Years
LessorOperatingLeasePaymentsToBeReceivedTwoYears
510000 USD
CY2022Q1 us-gaap Lessor Operating Lease Payments To Be Received Three Years
LessorOperatingLeasePaymentsToBeReceivedThreeYears
525000 USD
CY2022Q1 us-gaap Lessor Operating Lease Payments To Be Received Four Years
LessorOperatingLeasePaymentsToBeReceivedFourYears
134000 USD
CY2022Q1 us-gaap Lessor Operating Lease Payments To Be Received
LessorOperatingLeasePaymentsToBeReceived
2026000 USD
CY2021Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
8617000 USD
CY2022Q1 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
6981000 USD
CY2021Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
6861000 USD
CY2022Q1 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
1591000 USD
CY2021Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
1756000 USD
CY2022Q1 us-gaap Depreciation
Depreciation
200000 USD
CY2022Q1 us-gaap Finite Lived License Agreements Gross
FiniteLivedLicenseAgreementsGross
90000000 USD
CY2021Q4 us-gaap Finite Lived License Agreements Gross
FiniteLivedLicenseAgreementsGross
90000000 USD
CY2022Q1 us-gaap Finite Lived Intangible Assets Accumulated Amortization
FiniteLivedIntangibleAssetsAccumulatedAmortization
25879000 USD
CY2021Q4 us-gaap Finite Lived Intangible Assets Accumulated Amortization
FiniteLivedIntangibleAssetsAccumulatedAmortization
23875000 USD
CY2022Q1 us-gaap Intangible Assets Net Including Goodwill
IntangibleAssetsNetIncludingGoodwill
64121000 USD
CY2021Q4 us-gaap Intangible Assets Net Including Goodwill
IntangibleAssetsNetIncludingGoodwill
66125000 USD
CY2022Q1 us-gaap Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
2000000.0 USD
CY2022Q1 us-gaap Finite Lived Intangible Asset Useful Life
FiniteLivedIntangibleAssetUsefulLife
P8Y
CY2022Q1 pbyi Accrued Legal Verdict Expense Current
AccruedLegalVerdictExpenseCurrent
30030000 USD
CY2021Q4 pbyi Accrued Legal Verdict Expense Current
AccruedLegalVerdictExpenseCurrent
57137000 USD
CY2022Q1 us-gaap Accrued Royalties Current
AccruedRoyaltiesCurrent
8477000 USD
CY2021Q4 us-gaap Accrued Royalties Current
AccruedRoyaltiesCurrent
8829000 USD
CY2022Q1 pbyi Accrued Development Costs
AccruedDevelopmentCosts
1511000 USD
CY2021Q4 pbyi Accrued Development Costs
AccruedDevelopmentCosts
2663000 USD
CY2022Q1 pbyi Accrued Variable Consideration Current
AccruedVariableConsiderationCurrent
10807000 USD
CY2021Q4 pbyi Accrued Variable Consideration Current
AccruedVariableConsiderationCurrent
11406000 USD
CY2022Q1 us-gaap Accrued Bonuses Current
AccruedBonusesCurrent
1496000 USD
CY2021Q4 us-gaap Accrued Bonuses Current
AccruedBonusesCurrent
5083000 USD
CY2022Q1 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
4207000 USD
CY2021Q4 us-gaap Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
3878000 USD
CY2022Q1 pbyi Accrued Clinical Expenses Current
AccruedClinicalExpensesCurrent
1607000 USD
CY2021Q4 pbyi Accrued Clinical Expenses Current
AccruedClinicalExpensesCurrent
911000 USD
CY2022Q1 pbyi Accrued Professional Fees Liability Current
AccruedProfessionalFeesLiabilityCurrent
665000 USD
CY2021Q4 pbyi Accrued Professional Fees Liability Current
AccruedProfessionalFeesLiabilityCurrent
672000 USD
CY2022Q1 us-gaap Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
1787000 USD
CY2021Q4 us-gaap Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
674000 USD
CY2022Q1 pbyi Accrued Manufacturing Costs Current
AccruedManufacturingCostsCurrent
813000 USD
CY2021Q4 pbyi Accrued Manufacturing Costs Current
AccruedManufacturingCostsCurrent
690000 USD
CY2022Q1 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
437000 USD
CY2021Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
632000 USD
CY2022Q1 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
61837000 USD
CY2021Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
92575000 USD
CY2022Q1 pbyi Accrued Legal Verdict Expense Noncurrent
AccruedLegalVerdictExpenseNoncurrent
0 USD
CY2021Q4 pbyi Accrued Legal Verdict Expense Noncurrent
AccruedLegalVerdictExpenseNoncurrent
0 USD
CY2022Q1 pbyi Accrued Clinical Research Organization Services Noncurrent
AccruedClinicalResearchOrganizationServicesNoncurrent
719000 USD
CY2021Q4 pbyi Accrued Clinical Research Organization Services Noncurrent
AccruedClinicalResearchOrganizationServicesNoncurrent
878000 USD
CY2022Q1 us-gaap Other Accrued Liabilities Noncurrent
OtherAccruedLiabilitiesNoncurrent
37000 USD
CY2021Q4 us-gaap Other Accrued Liabilities Noncurrent
OtherAccruedLiabilitiesNoncurrent
37000 USD
CY2022Q1 pbyi Accrued Liabilities Noncurrent
AccruedLiabilitiesNoncurrent
756000 USD
CY2021Q4 pbyi Accrued Liabilities Noncurrent
AccruedLiabilitiesNoncurrent
915000 USD
CY2022Q1 us-gaap Accrued Liabilities Current And Noncurrent
AccruedLiabilitiesCurrentAndNoncurrent
62593000 USD
CY2021Q4 us-gaap Accrued Liabilities Current And Noncurrent
AccruedLiabilitiesCurrentAndNoncurrent
93490000 USD
CY2021Q4 pbyi Restructuring Percentage Of Reduction In Headcount
RestructuringPercentageOfReductionInHeadcount
0.13 pure
CY2022Q1 us-gaap Debt Instrument Carrying Amount
DebtInstrumentCarryingAmount
102000000 USD
CY2022Q1 us-gaap Debt Instrument Unamortized Discount Premium And Debt Issuance Costs Net
DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
4619000 USD
CY2022Q1 us-gaap Long Term Debt Noncurrent
LongTermDebtNoncurrent
97381000 USD
CY2022Q1 us-gaap Long Term Debt Maturities Repayments Of Principal Remainder Of Fiscal Year
LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear
0 USD
CY2022Q1 us-gaap Long Term Debt Maturities Repayments Of Principal In Next Twelve Months
LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths
0 USD
CY2022Q1 us-gaap Long Term Debt Maturities Repayments Of Principal In Year Two
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo
33997000 USD
CY2022Q1 us-gaap Long Term Debt Maturities Repayments Of Principal In Year Three
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree
45329000 USD
CY2022Q1 us-gaap Long Term Debt Maturities Repayments Of Principal In Year Four
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour
22674000 USD
CY2022Q1 us-gaap Long Term Debt
LongTermDebt
102000000 USD
CY2022Q1 us-gaap Accumulated Amortization Deferred Finance Costs
AccumulatedAmortizationDeferredFinanceCosts
791000 USD
CY2021Q4 us-gaap Accumulated Amortization Deferred Finance Costs
AccumulatedAmortizationDeferredFinanceCosts
502000 USD
CY2022Q1 us-gaap Debt Instrument Unamortized Discount Premium And Debt Issuance Costs Net
DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
4619000 USD
CY2021Q4 us-gaap Debt Instrument Unamortized Discount Premium And Debt Issuance Costs Net
DebtInstrumentUnamortizedDiscountPremiumAndDebtIssuanceCostsNet
4908000 USD
CY2022Q1 us-gaap Amortization Of Financing Costs
AmortizationOfFinancingCosts
200000 USD
CY2021Q1 us-gaap Amortization Of Financing Costs
AmortizationOfFinancingCosts
500000 USD
CY2022Q1 us-gaap Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
0
CY2022Q1 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
100000000
CY2022Q1 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.0001
CY2011Q4 pbyi Ordinary Shares Ownership Percentage
OrdinarySharesOwnershipPercentage
0.20 pure
CY2022Q1 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
3148000 USD
CY2021Q1 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
5860000 USD
CY2022Q1 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
1.64
CY2021Q1 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
8.54
CY2021Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares
835297
CY2021Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue
7.76
CY2022Q1 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
482353
CY2022Q1 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
1.64
CY2022Q1 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
178552
CY2022Q1 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue
8.43
CY2022Q1 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares
1139098
CY2022Q1 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue
5.06
CY2022Q1 us-gaap Defined Contribution Plan Cost Recognized
DefinedContributionPlanCostRecognized
400000 USD
CY2021Q1 us-gaap Defined Contribution Plan Cost Recognized
DefinedContributionPlanCostRecognized
600000 USD
CY2022Q1 pbyi Milestone Payments Maximum Amount
MilestonePaymentsMaximumAmount
187500000 USD
pbyi Percentage Of Unpaid Portion Of Milestone Payments Interest Rate
PercentageOfUnpaidPortionOfMilestonePaymentsInterestRate
0.0625 pure
pbyi Milestone Payment
MilestonePayment
1800000 USD

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