2023 Q1 Form 10-K Financial Statement

#000095017023006377 Filed on March 07, 2023

View on sec.gov

Income Statement

Concept 2023 Q1 2022 Q4 2022
Revenue $0.00 $11.00K $2.900M
YoY Change
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin $3.168M $2.925M $13.14M
YoY Change -9.61% 39.62% -52.32%
% of Gross Profit
Research & Development $6.504M $5.607M $25.02M
YoY Change 16.56% -31.76% -49.6%
% of Gross Profit
Depreciation & Amortization $696.0K $694.0K $2.800M
YoY Change 1.02% -1.56% 7.69%
% of Gross Profit
Operating Expenses $9.672M $8.532M $38.03M
YoY Change 6.46% -17.25% -51.21%
Operating Profit -$9.672M -$35.11M
YoY Change 6.46% -54.73%
Interest Expense $853.0K -$888.0K $3.154M
YoY Change -224.89% 20.33% -366.84%
% of Operating Profit
Other Income/Expense, Net -$376.0K $250.0K -$2.625M
YoY Change -46.51% -5100.0% 118.39%
Pretax Income -$10.05M -$9.159M -$37.73M
YoY Change 2.66% -22.34% -52.09%
Income Tax
% Of Pretax Income
Net Earnings -$10.05M -$9.159M -$37.73M
YoY Change 2.66% -22.34% -52.09%
Net Earnings / Revenue -83263.64% -1301.03%
Basic Earnings Per Share -$0.04 -$0.17
Diluted Earnings Per Share -$0.04 -$0.04 -$0.17
COMMON SHARES
Basic Shares Outstanding 240.6M 216.2M 217.1M
Diluted Shares Outstanding 239.7M 217.1M

Balance Sheet

Concept 2023 Q1 2022 Q4 2022
SHORT-TERM ASSETS
Cash & Short-Term Investments $23.50M $39.06M $39.06M
YoY Change -65.58% -48.64% -48.64%
Cash & Equivalents $23.50M $39.06M $39.06M
Short-Term Investments
Other Short-Term Assets $14.69M $14.74M $14.74M
YoY Change 868.23% 784.57% 784.57%
Inventory
Prepaid Expenses
Receivables $0.00 $4.000K $4.000K
Other Receivables $0.00 $0.00 $0.00
Total Short-Term Assets $38.18M $53.80M $53.80M
YoY Change -45.27% -31.75% -31.75%
LONG-TERM ASSETS
Property, Plant & Equipment $7.889M $8.460M $10.60M
YoY Change -23.49% -22.68% -31.02%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments
YoY Change
Other Assets $500.0K $500.0K $542.0K
YoY Change -20.13% -20.76% -19.47%
Total Long-Term Assets $10.45M $11.14M $11.14M
YoY Change -31.31% -30.54% -30.54%
TOTAL ASSETS
Total Short-Term Assets $38.18M $53.80M $53.80M
Total Long-Term Assets $10.45M $11.14M $11.14M
Total Assets $48.64M $64.94M $64.94M
YoY Change -42.77% -31.55% -31.55%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $1.380M $1.389M $1.389M
YoY Change 128.1% 1.54% 1.54%
Accrued Expenses $4.120M $5.454M $6.012M
YoY Change -30.06% -10.24% -11.65%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due $10.99M $16.77M $16.77M
YoY Change -21.48% 113.08% 113.08%
Total Short-Term Liabilities $17.06M $24.17M $24.17M
YoY Change -19.64% 50.65% 50.65%
LONG-TERM LIABILITIES
Long-Term Debt $0.00 $0.00 $0.00
YoY Change -100.0% -100.0% -100.0%
Other Long-Term Liabilities $28.00K $28.00K $2.216M
YoY Change -99.35% -50.94%
Total Long-Term Liabilities $28.00K $28.00K $2.216M
YoY Change -99.73% -99.83% -89.33%
TOTAL LIABILITIES
Total Short-Term Liabilities $17.06M $24.17M $24.17M
Total Long-Term Liabilities $28.00K $28.00K $2.216M
Total Liabilities $19.13M $26.38M $26.38M
YoY Change -46.67% -28.33% -28.33%
SHAREHOLDERS EQUITY
Retained Earnings -$890.7M -$880.6M
YoY Change 4.47% 4.48%
Common Stock $920.2M $919.2M
YoY Change 2.04% 2.03%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $29.51M $38.56M $38.56M
YoY Change
Total Liabilities & Shareholders Equity $48.64M $64.94M $64.94M
YoY Change -42.77% -31.55% -31.55%

Cashflow Statement

Concept 2023 Q1 2022 Q4 2022
OPERATING ACTIVITIES
Net Income -$10.05M -$9.159M -$37.73M
YoY Change 2.66% -22.34% -52.09%
Depreciation, Depletion And Amortization $696.0K $694.0K $2.800M
YoY Change 1.02% -1.56% 7.69%
Cash From Operating Activities -$9.381M -$7.130M -$29.23M
YoY Change 20.73% -52.86% -52.44%
INVESTING ACTIVITIES
Capital Expenditures $61.00K $116.0K $216.0K
YoY Change 110.34% -132.31% -93.5%
Acquisitions
YoY Change
Other Investing Activities $38.00K $23.00K $23.00K
YoY Change
Cash From Investing Activities -$23.00K -$93.00K -$193.0K
YoY Change -20.69% -74.09% -94.19%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net -$14.68M
YoY Change
Debt Paid & Issued, Net $6.250M $8.333M
YoY Change
Cash From Financing Activities -6.158M 8.474M 6.367M
YoY Change -4655.91% -75.3%
NET CHANGE
Cash From Operating Activities -9.381M -7.130M -29.23M
Cash From Investing Activities -23.00K -93.00K -193.0K
Cash From Financing Activities -6.158M 8.474M 6.367M
Net Change In Cash -15.56M 1.251M -23.06M
YoY Change 99.54% -107.98% -40.9%
FREE CASH FLOW
Cash From Operating Activities -$9.381M -$7.130M -$29.23M
Capital Expenditures $61.00K $116.0K $216.0K
Free Cash Flow -$9.442M -$7.246M -$29.45M
YoY Change 21.07% -50.93% -54.55%

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CY2022Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
52996000
CY2021Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
76054000
CY2022 us-gaap Interest Paid Net
InterestPaidNet
2171000
CY2021 us-gaap Interest Paid Net
InterestPaidNet
630000
CY2022 us-gaap Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
91000
CY2021 us-gaap Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
134000
CY2022Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
53000000.0
CY2022Q4 us-gaap Restricted Cash
RestrictedCash
13900000
CY2022Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-880600000
CY2022 us-gaap Use Of Estimates
UseOfEstimates
<p style="text-indent:0.0%;font-size:10.0pt;margin-top:12.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:bold;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;font-style:italic;min-width:fit-content;">Use of Estimates</span></p><p style="text-indent:0.0%;font-size:10.0pt;margin-top:6.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the date of the financial statements and the reported amounts of revenue and expenses during the reporting period. Although the Company regularly assesses these estimates, actual results could differ from those estimates. Changes in estimates are recorded in the period in which they become known.</span></p><p style="text-indent:0.0%;font-size:10.0pt;margin-top:6.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">The Company’s most significant estimates and judgments used in the preparation of the financial statements are:</span></p><div style="margin-left:6.667%;text-indent:0.0%;display:flex;margin-top:6.0pt;justify-content:flex-start;align-items:baseline;margin-bottom:0.0pt;min-width:4.537%;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;text-indent:0;display:inline-flex;font-size:10.0pt;font-family:Times New Roman;justify-content:flex-start;min-width:4.86108878960282%;">•</span><div style="display:inline;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">Clinical trial expenses and other research and development expenses;</span></div></div><div style="margin-left:6.667%;text-indent:0.0%;display:flex;margin-top:6.0pt;justify-content:flex-start;align-items:baseline;margin-bottom:0.0pt;min-width:4.537%;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;text-indent:0;display:inline-flex;font-size:10.0pt;font-family:Times New Roman;justify-content:flex-start;min-width:4.86108878960282%;">•</span><div style="display:inline;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">Collaboration agreements;</span></div></div><div style="margin-left:6.667%;text-indent:0.0%;display:flex;margin-top:6.0pt;justify-content:flex-start;align-items:baseline;margin-bottom:0.0pt;min-width:4.537%;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;text-indent:0;display:inline-flex;font-size:10.0pt;font-family:Times New Roman;justify-content:flex-start;min-width:4.86108878960282%;">•</span><div style="display:inline;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">Fair value measurements of stock-based compensation; and</span></div></div><div style="margin-left:6.667%;text-indent:0.0%;display:flex;margin-top:6.0pt;justify-content:flex-start;align-items:baseline;margin-bottom:0.0pt;min-width:4.537%;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;text-indent:0;display:inline-flex;font-size:10.0pt;font-family:Times New Roman;justify-content:flex-start;min-width:4.86108878960282%;">•</span><div style="display:inline;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">Income taxes.</span></div></div>
CY2022 us-gaap Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
<p style="text-indent:0.0%;font-size:10.0pt;margin-top:12.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:bold;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;font-style:italic;min-width:fit-content;">Concentrations of Credit Risk</span></p><p style="text-indent:0.0%;font-size:10.0pt;margin-top:6.0pt;font-family:Times New Roman;margin-bottom:0.0pt;text-align:left;"><span style="background-color:rgba(0,0,0,0);color:rgba(0,0,0,1);white-space:pre-wrap;font-weight:normal;font-size:10.0pt;font-family:&quot;Times New Roman&quot;, serif;min-width:fit-content;">Financial instruments which potentially subject the Company to concentrations of credit risk consist principally of cash and cash equivalents. The Company maintains cash accounts in commercial banks, which may, at times, exceed federally insured limits. The Company has not experienced any losses in such accounts. The Company believes it is not exposed to any significant credit risk on cash and cash equivalents.</span></p>
CY2021 us-gaap Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
600000
CY2022 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
2900000
CY2021 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
400000
CY2022 us-gaap Share Based Compensation
ShareBasedCompensation
3528000
CY2021 us-gaap Share Based Compensation
ShareBasedCompensation
10774000
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
0.77
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
2.62
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
0.0163
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
0.0421
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
0.0050
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
0.0136
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
0.7449
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
0.8875
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
0.7253
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
0.7480
CY2022 us-gaap Net Income Loss
NetIncomeLoss
-37730000
CY2021 us-gaap Net Income Loss
NetIncomeLoss
-78751000
CY2022 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
217130311
CY2022 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
217130311
CY2021 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
214399074
CY2021 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
214399074
CY2022 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.17
CY2022 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.17
CY2021 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.37
CY2021 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.37
CY2022 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
34270026
CY2021 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
34819291
CY2022Q4 us-gaap Debt Instrument Carrying Amount
DebtInstrumentCarryingAmount
16765000
CY2021Q4 us-gaap Debt Instrument Carrying Amount
DebtInstrumentCarryingAmount
24118000
CY2022Q4 us-gaap Long Term Debt Current
LongTermDebtCurrent
16765000
CY2021Q4 us-gaap Long Term Debt Current
LongTermDebtCurrent
7868000
CY2022Q4 us-gaap Long Term Debt Noncurrent
LongTermDebtNoncurrent
0
CY2021Q4 us-gaap Long Term Debt Noncurrent
LongTermDebtNoncurrent
16250000
CY2021Q3 us-gaap Debt Instrument Basis Spread On Variable Rate1
DebtInstrumentBasisSpreadOnVariableRate1
0.045
CY2022 tcrt Interest Expense Amortized Date
InterestExpenseAmortizedDate
2023-08-01
CY2022 us-gaap Interest Expense Debt
InterestExpenseDebt
3200000
CY2021 us-gaap Interest Expense Debt
InterestExpenseDebt
1200000
CY2022Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
18267000
CY2021Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
18354000
CY2022Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
9807000
CY2021Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
7413000
CY2022Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
8460000
CY2021Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
10941000
CY2022 us-gaap Depreciation
Depreciation
2800000
CY2021 us-gaap Depreciation
Depreciation
2600000
CY2022Q4 tcrt Accrued Clinical Expenses Current
AccruedClinicalExpensesCurrent
2200000
CY2021Q4 tcrt Accrued Clinical Expenses Current
AccruedClinicalExpensesCurrent
1677000
CY2022Q4 us-gaap Accrued Bonuses Current
AccruedBonusesCurrent
1160000
CY2021Q4 us-gaap Accrued Bonuses Current
AccruedBonusesCurrent
1922000
CY2022Q4 us-gaap Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
534000
CY2021Q4 us-gaap Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
825000
CY2022Q4 tcrt Accrued Preclinical Services Current
AccruedPreclinicalServicesCurrent
198000
CY2021Q4 tcrt Accrued Preclinical Services Current
AccruedPreclinicalServicesCurrent
363000
CY2022Q4 tcrt Accrued Manufacturing Costs Current
AccruedManufacturingCostsCurrent
1177000
CY2021Q4 tcrt Accrued Manufacturing Costs Current
AccruedManufacturingCostsCurrent
1056000
CY2022Q4 tcrt Accrued Consulting Fees Current
AccruedConsultingFeesCurrent
16000
CY2021Q4 tcrt Accrued Consulting Fees Current
AccruedConsultingFeesCurrent
66000
CY2022Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
169000
CY2021Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
167000
CY2022Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
5454000
CY2021Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
6076000
CY2021Q4 us-gaap Operating Lease Residual Value Of Leased Asset
OperatingLeaseResidualValueOfLeasedAsset
1400000
CY2021 us-gaap Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
600000
CY2021 us-gaap Other Asset Impairment Charges
OtherAssetImpairmentCharges
100000
CY2022Q4 tcrt Discounted Risk Adjusted Rates
DiscountedRiskAdjustedRates
0.10
CY2019Q4 tcrt Operating Leases Expiration Month And Year
OperatingLeasesExpirationMonthAndYear
2027-02
CY2020Q2 tcrt Operating Leases Expiration Month And Year
OperatingLeasesExpirationMonthAndYear
2027-02
CY2022 tcrt Gain Loss On Modification Of Lease
GainLossOnModificationOfLease
100000
CY2022Q4 tcrt Operating Leases Future Minimum Monthly Payment Due Through Year Four
OperatingLeasesFutureMinimumMonthlyPaymentDueThroughYearFour
7000
CY2022 tcrt Annual Base Rent
AnnualBaseRent
0.030
CY2022 us-gaap Operating Lease Cost
OperatingLeaseCost
756000
CY2021 us-gaap Operating Lease Cost
OperatingLeaseCost
1394000
CY2022 us-gaap Lease Cost
LeaseCost
756000
CY2021 us-gaap Lease Cost
LeaseCost
1394000
CY2022Q4 us-gaap Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
P4Y1M17D
CY2021Q4 us-gaap Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
P5Y6M29D
CY2022Q4 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.0826
CY2021Q4 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.0800
CY2022 us-gaap Operating Lease Payments
OperatingLeasePayments
800000
CY2022Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
0
CY2022Q4 us-gaap Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
757000
CY2022Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
780000
CY2022Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
804000
CY2022Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
712000
CY2022Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
158000
CY2022Q4 us-gaap Lessee Operating Lease Liability Payments Due After Year Five
LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive
31000
CY2022Q4 us-gaap Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
3242000
CY2022Q4 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
496000
CY2022Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
2746000
CY2022Q4 tcrt Sublease Area
SubleaseArea
4772
CY2022 us-gaap Lessee Operating Lease Option To Extend
LesseeOperatingLeaseOptionToExtend
The term of the sub-sublease is from July 1, 2022 to June 30, 2025 and provides the sub-subtenant with an option to extend through to July 31, 2026.
CY2022Q4 us-gaap Lessor Operating Lease Payments To Be Received Next Twelve Months
LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths
200000
CY2022Q4 us-gaap Lessor Operating Lease Payments To Be Received Two Years
LessorOperatingLeasePaymentsToBeReceivedTwoYears
200000
CY2022Q4 us-gaap Lessor Operating Lease Payments To Be Received Three Years
LessorOperatingLeasePaymentsToBeReceivedThreeYears
100000
CY2021 us-gaap Royalty Expense
RoyaltyExpense
0
CY2022 us-gaap Royalty Expense
RoyaltyExpense
0
CY2019Q3 us-gaap Proceeds From Issuance Of Private Placement
ProceedsFromIssuanceOfPrivatePlacement
52500000
CY2021 us-gaap Severance Costs1
SeveranceCosts1
3657000
CY2022Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
171070000
CY2021Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
164486000
CY2022Q4 tcrt Deferred Tax Assets Start Up And Pre Clinical Studies
DeferredTaxAssetsStartUpAndPreClinicalStudies
17204000
CY2021Q4 tcrt Deferred Tax Assets Start Up And Pre Clinical Studies
DeferredTaxAssetsStartUpAndPreClinicalStudies
21705000
CY2022Q4 us-gaap Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
40116000
CY2021Q4 us-gaap Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
39817000
CY2022Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
698000
CY2021Q4 us-gaap Deferred Tax Assets Tax Deferred Expense Compensation And Benefits
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefits
706000
CY2022Q4 tcrt Deferred Tax Assets Capitalized Acquisition Costs
DeferredTaxAssetsCapitalizedAcquisitionCosts
2180000
CY2021Q4 tcrt Deferred Tax Assets Capitalized Acquisition Costs
DeferredTaxAssetsCapitalizedAcquisitionCosts
2946000
CY2022Q4 tcrt Deferred Tax Assets Lease Liability
DeferredTaxAssetsLeaseLiability
618000
CY2021Q4 tcrt Deferred Tax Assets Lease Liability
DeferredTaxAssetsLeaseLiability
1278000
CY2022Q4 tcrt Deferred Tax Assets Depreciation
DeferredTaxAssetsDepreciation
239000
CY2021Q4 tcrt Deferred Tax Assets Depreciation
DeferredTaxAssetsDepreciation
102000
CY2022Q4 tcrt Deferred Tax Assets Research Expenses Capitalized
DeferredTaxAssetsResearchExpensesCapitalized
5156000
CY2021Q4 tcrt Deferred Tax Assets Research Expenses Capitalized
DeferredTaxAssetsResearchExpensesCapitalized
0
CY2022Q4 us-gaap Deferred Tax Assets Other
DeferredTaxAssetsOther
27000
CY2021Q4 us-gaap Deferred Tax Assets Other
DeferredTaxAssetsOther
156000
CY2022Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
237308000
CY2021Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
231196000
CY2022Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
236827000
CY2021Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
230119000
CY2022Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
481000
CY2021Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
1077000
CY2022Q4 tcrt Deferred Tax Liability Right Of Use Asset
DeferredTaxLiabilityRightOfUseAsset
481000
CY2021Q4 tcrt Deferred Tax Liability Right Of Use Asset
DeferredTaxLiabilityRightOfUseAsset
1077000
CY2022Q4 us-gaap Deferred Tax Liabilities
DeferredTaxLiabilities
481000
CY2021Q4 us-gaap Deferred Tax Liabilities
DeferredTaxLiabilities
1077000
CY2022Q4 us-gaap Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
0
CY2021Q4 us-gaap Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
0
CY2022Q4 us-gaap Deferred Tax Assets Operating Loss Carryforwards Not Subject To Expiration
DeferredTaxAssetsOperatingLossCarryforwardsNotSubjectToExpiration
323800000
CY2022 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
6700000
CY2022 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
CY2021 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.21
CY2022 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.03
CY2021 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.03
CY2022 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Research And Development
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopment
0.02
CY2021 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Research And Development
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopment
0.03
CY2022 tcrt Effective Income Tax Rate Reconciliation Nondeductible Expense Research And Development True Up
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopmentTrueUp
-0.02
CY2021 tcrt Effective Income Tax Rate Reconciliation Nondeductible Expense Research And Development True Up
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseResearchAndDevelopmentTrueUp
0
CY2022 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
-0.01
CY2021 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
-0.01
CY2022 tcrt Effective Income Tax Rate Reconciliation Nondeductible Expense Federal Rate Change
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseFederalRateChange
-0.05
CY2021 tcrt Effective Income Tax Rate Reconciliation Nondeductible Expense Federal Rate Change
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseFederalRateChange
-0.02
CY2022 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
-0.18
CY2021 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
-0.24
CY2022 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0
CY2021 us-gaap Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
0
CY2022 us-gaap Unrecognized Tax Benefits Period Increase Decrease
UnrecognizedTaxBenefitsPeriodIncreaseDecrease
0
CY2021 us-gaap Unrecognized Tax Benefits Period Increase Decrease
UnrecognizedTaxBenefitsPeriodIncreaseDecrease
0
CY2022Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
15460088
CY2022 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
21000
CY2021 us-gaap Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
1000000.0
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
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26000
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
800000
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
6840719
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
3.81
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod
9380438
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
2.62
CY2021 us-gaap Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
363109
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
2.86
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
5192179
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
3.65
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
10665869
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
2.87
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriod
4697500
CY2022 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
1.08
CY2022 us-gaap Stock Issued During Period Shares Stock Options Exercised
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26250
CY2022 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
0.80
CY2022 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
4928497
CY2022 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
3.34
CY2022Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
10408622
CY2022Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
1.84
CY2022 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
P8Y8M8D
CY2022Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
3000
CY2022Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
3891598
CY2022Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
2.46
CY2022 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
P8Y29D
CY2022Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
0
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
4410312
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
3.85
CY2021 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
P7Y6M10D
CY2021Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
0
CY2022Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
15460088
CY2022 us-gaap Defined Benefit Plan Contributions By Employer
DefinedBenefitPlanContributionsByEmployer
500000
CY2021 us-gaap Defined Benefit Plan Contributions By Employer
DefinedBenefitPlanContributionsByEmployer
700000

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