2023 Q1 Form 10-K Financial Statement
#000193765323000011 Filed on March 07, 2023
Income Statement
Concept | 2023 Q1 | 2022 Q4 | 2022 |
---|---|---|---|
Revenue | $35.58M | $402.5M | $412.5M |
YoY Change | 1756.89% | 1925.63% | 1446.03% |
Cost Of Revenue | |||
YoY Change | |||
Gross Profit | |||
YoY Change | |||
Gross Profit Margin | |||
Selling, General & Admin | $16.95M | $30.13M | $73.36M |
YoY Change | 40.15% | 414.71% | 72.36% |
% of Gross Profit | |||
Research & Development | $45.91M | $52.97M | $208.6M |
YoY Change | -26.55% | -3.46% | 4.43% |
% of Gross Profit | |||
Depreciation & Amortization | $1.584M | $1.681M | $6.220M |
YoY Change | -35.77% | 68.94% | -4.78% |
% of Gross Profit | |||
Operating Expenses | $45.91M | $83.10M | $208.6M |
YoY Change | -38.46% | 36.86% | -13.91% |
Operating Profit | -$27.28M | $130.5M | |
YoY Change | -62.47% | -160.53% | |
Interest Expense | $4.805M | $1.068M | $3.596M |
YoY Change | -8108.33% | 253.64% | 13.94% |
% of Operating Profit | 2.75% | ||
Other Income/Expense, Net | -$487.0K | -$27.00K | $1.110M |
YoY Change | -1136.17% | -212.5% | 840.68% |
Pretax Income | -$22.96M | $320.4M | $135.2M |
YoY Change | -68.41% | -890.75% | -163.68% |
Income Tax | $1.390M | $11.01M | $10.89M |
% Of Pretax Income | 3.43% | 8.05% | |
Net Earnings | -$24.35M | $309.4M | $124.3M |
YoY Change | -66.47% | -890.33% | -158.69% |
Net Earnings / Revenue | -68.45% | 76.88% | 30.14% |
Basic Earnings Per Share | -$0.36 | $1.91 | |
Diluted Earnings Per Share | -$0.37 | $4.64 | $1.90 |
COMMON SHARES | |||
Basic Shares Outstanding | 64.04M shares | 63.00M shares | 65.19M shares |
Diluted Shares Outstanding | 66.74M shares | 65.25M shares |
Balance Sheet
Concept | 2023 Q1 | 2022 Q4 | 2022 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $340.8M | $492.2M | $492.2M |
YoY Change | 13.4% | 94.86% | 94.86% |
Cash & Equivalents | $181.6M | $400.9M | $400.9M |
Short-Term Investments | $159.2M | $91.32M | $91.32M |
Other Short-Term Assets | $18.67M | $19.07M | $19.07M |
YoY Change | -3.09% | -4.62% | -4.62% |
Inventory | |||
Prepaid Expenses | |||
Receivables | $66.92M | $33.40M | $33.40M |
Other Receivables | $0.00 | $0.00 | $0.00 |
Total Short-Term Assets | $426.4M | $544.7M | $544.7M |
YoY Change | 31.59% | 88.99% | 88.99% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $23.51M | $24.71M | $47.65M |
YoY Change | -52.69% | -50.35% | -4.26% |
Goodwill | $12.02M | $12.02M | |
YoY Change | 0.0% | ||
Intangibles | |||
YoY Change | |||
Long-Term Investments | $72.47M | $886.0K | $886.0K |
YoY Change | 8079.91% | 0.0% | 0.0% |
Other Assets | $18.36M | $17.08M | $17.08M |
YoY Change | -12.64% | 1.85% | 1.85% |
Total Long-Term Assets | $174.4M | $104.0M | $104.0M |
YoY Change | 64.57% | 3.08% | 3.08% |
TOTAL ASSETS | |||
Total Short-Term Assets | $426.4M | $544.7M | $544.7M |
Total Long-Term Assets | $174.4M | $104.0M | $104.0M |
Total Assets | $600.7M | $648.7M | $648.7M |
YoY Change | 39.72% | 66.71% | 66.71% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $6.433M | $7.863M | $7.863M |
YoY Change | -54.14% | 51.97% | 51.97% |
Accrued Expenses | $54.40M | $81.09M | $81.09M |
YoY Change | -10.71% | 43.06% | 43.06% |
Deferred Revenue | $2.353M | $2.353M | |
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $67.32M | $95.63M | $95.63M |
YoY Change | -15.82% | 33.08% | 33.08% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $121.0K | $124.0K | $124.0K |
YoY Change | 31.52% | 24.0% | 24.0% |
Other Long-Term Liabilities | $3.595M | $3.101M | $58.23M |
YoY Change | -94.55% | -95.34% | -12.45% |
Total Long-Term Liabilities | $3.595M | $3.101M | $58.36M |
YoY Change | -94.56% | -95.34% | -12.39% |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $67.32M | $95.63M | $95.63M |
Total Long-Term Liabilities | $3.595M | $3.101M | $58.36M |
Total Liabilities | $127.2M | $155.8M | $155.8M |
YoY Change | -13.78% | 11.23% | 11.23% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$583.1M | -$558.8M | |
YoY Change | -18.2% | ||
Common Stock | $1.053B | $1.038B | |
YoY Change | 10.55% | ||
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $473.5M | $493.0M | $493.0M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $600.7M | $648.7M | $648.7M |
YoY Change | 39.72% | 66.71% | 66.71% |
Cashflow Statement
Concept | 2023 Q1 | 2022 Q4 | 2022 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$24.35M | $309.4M | $124.3M |
YoY Change | -66.47% | -890.33% | -158.69% |
Depreciation, Depletion And Amortization | $1.584M | $1.681M | $6.220M |
YoY Change | -35.77% | 68.94% | -4.78% |
Cash From Operating Activities | -$83.19M | $327.4M | $144.1M |
YoY Change | 50.13% | -748.12% | -174.88% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $386.0K | $883.0K | $8.150M |
YoY Change | -91.79% | -84.3% | -38.65% |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | -$137.8M | -$21.18M | -$40.72M |
YoY Change | -645.28% | -662.3% | -125.79% |
Cash From Investing Activities | -$138.2M | -$22.06M | -$53.85M |
YoY Change | -771.83% | 1088.21% | -137.24% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | $107.5M | ||
YoY Change | 1165.4% | ||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | $1.738M | -377.0K | $108.6M |
YoY Change | -98.4% | -154.72% | 1255.41% |
NET CHANGE | |||
Cash From Operating Activities | -$83.19M | 327.4M | $144.1M |
Cash From Investing Activities | -$138.2M | -22.06M | -$53.85M |
Cash From Financing Activities | $1.738M | -377.0K | $108.6M |
Net Change In Cash | -$219.3M | 304.9M | $199.0M |
YoY Change | -397.31% | -690.05% | -599.56% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$83.19M | $327.4M | $144.1M |
Capital Expenditures | $386.0K | $883.0K | $8.150M |
Free Cash Flow | -$83.58M | $326.5M | $136.0M |
YoY Change | 39.03% | -681.61% | -166.08% |
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CY2022 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
412482000 | usd |
CY2021 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
26680000 | usd |
CY2020 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
38951000 | usd |
CY2022 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
208596000 | usd |
CY2021 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
199752000 | usd |
CY2020 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
171203000 | usd |
CY2022 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
73358000 | usd |
CY2021 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
42561000 | usd |
CY2020 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
55216000 | usd |
CY2022 | us-gaap |
Costs And Expenses
CostsAndExpenses
|
281954000 | usd |
CY2021 | us-gaap |
Costs And Expenses
CostsAndExpenses
|
242313000 | usd |
CY2020 | us-gaap |
Costs And Expenses
CostsAndExpenses
|
226419000 | usd |
CY2022 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
130528000 | usd |
CY2021 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-215633000 | usd |
CY2020 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-187468000 | usd |
CY2022 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
3596000 | usd |
CY2021 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
1965000 | usd |
CY2020 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
5697000 | usd |
CY2022 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
1110000 | usd |
CY2021 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
1309000 | usd |
CY2020 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
1648000 | usd |
CY2022 | us-gaap |
Other Operating Income Expense Net
OtherOperatingIncomeExpenseNet
|
4706000 | usd |
CY2021 | us-gaap |
Other Operating Income Expense Net
OtherOperatingIncomeExpenseNet
|
3274000 | usd |
CY2020 | us-gaap |
Other Operating Income Expense Net
OtherOperatingIncomeExpenseNet
|
7345000 | usd |
CY2022 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
135234000 | usd |
CY2021 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-212359000 | usd |
CY2020 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-180123000 | usd |
CY2022 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
10893000 | usd |
CY2021 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-516000 | usd |
CY2020 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
429000 | usd |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
124341000 | usd |
CY2022 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
124341000 | usd |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-211843000 | usd |
CY2021 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-211843000 | usd |
CY2020 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-180552000 | usd |
CY2020 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-180552000 | usd |
CY2022 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
1.91 | |
CY2021 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-4.11 | |
CY2020 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-3.58 | |
CY2022 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
1.90 | |
CY2021 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-4.61 | |
CY2020 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-3.58 | |
CY2022 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
65194775 | shares |
CY2021 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
51553869 | shares |
CY2020 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
50382497 | shares |
CY2022 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
65249184 | shares |
CY2021 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
52131596 | shares |
CY2020 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
50382497 | shares |
CY2019Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
245681000 | usd |
CY2020 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
15430000 | usd |
CY2020 | us-gaap |
Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
|
1618000 | usd |
CY2020 | zyme |
Adjustments To Additional Paid In Capital Fair Value Adjustment Reclassification Of Stock Options To Liabilities
AdjustmentsToAdditionalPaidInCapitalFairValueAdjustmentReclassificationOfStockOptionsToLiabilities
|
110000 | usd |
CY2020 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
26945000 | usd |
CY2020 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
300910000 | usd |
CY2020 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-180552000 | usd |
CY2020Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
409922000 | usd |
CY2021 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
9660000 | usd |
CY2021 | us-gaap |
Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
|
3080000 | usd |
CY2021 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Net Of Forfeitures
StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures
|
0 | usd |
CY2021 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
38275000 | usd |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-211843000 | usd |
CY2021Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
249094000 | usd |
CY2022 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
280000 | usd |
CY2022 | us-gaap |
Stock Issued During Period Value Employee Stock Purchase Plan
StockIssuedDuringPeriodValueEmployeeStockPurchasePlan
|
2191000 | usd |
CY2022 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Net Of Forfeitures
StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures
|
0 | usd |
CY2022 | us-gaap |
Stock Issued During Period Value Conversion Of Convertible Securities
StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
|
0 | usd |
CY2022 | zyme |
Stock Issued During Period Value Exchange Of Shares Per The Redomiciliation
StockIssuedDuringPeriodValueExchangeOfSharesPerTheRedomiciliation
|
0 | usd |
CY2022 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
9516000 | usd |
CY2022 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
107534000 | usd |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
124341000 | usd |
CY2022Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
492956000 | usd |
CY2022 | us-gaap |
Profit Loss
ProfitLoss
|
124341000 | usd |
CY2021 | us-gaap |
Profit Loss
ProfitLoss
|
-211843000 | usd |
CY2020 | us-gaap |
Profit Loss
ProfitLoss
|
-180552000 | usd |
CY2022 | us-gaap |
Depreciation
Depreciation
|
6220000 | usd |
CY2021 | us-gaap |
Depreciation
Depreciation
|
3739000 | usd |
CY2020 | us-gaap |
Depreciation
Depreciation
|
3355000 | usd |
CY2022 | us-gaap |
Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
|
1015000 | usd |
CY2021 | us-gaap |
Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
|
2793000 | usd |
CY2020 | us-gaap |
Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
|
4160000 | usd |
CY2022 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
4015000 | usd |
CY2021 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
10756000 | usd |
CY2020 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
29116000 | usd |
CY2022 | us-gaap |
Operating Lease Right Of Use Asset Amortization Expense
OperatingLeaseRightOfUseAssetAmortizationExpense
|
4769000 | usd |
CY2021 | us-gaap |
Operating Lease Right Of Use Asset Amortization Expense
OperatingLeaseRightOfUseAssetAmortizationExpense
|
3051000 | usd |
CY2020 | us-gaap |
Operating Lease Right Of Use Asset Amortization Expense
OperatingLeaseRightOfUseAssetAmortizationExpense
|
2764000 | usd |
CY2022 | us-gaap |
Increase Decrease In Deferred Income Taxes
IncreaseDecreaseInDeferredIncomeTaxes
|
-1940000 | usd |
CY2021 | us-gaap |
Increase Decrease In Deferred Income Taxes
IncreaseDecreaseInDeferredIncomeTaxes
|
953000 | usd |
CY2020 | us-gaap |
Increase Decrease In Deferred Income Taxes
IncreaseDecreaseInDeferredIncomeTaxes
|
-266000 | usd |
CY2022 | zyme |
Licensing Agreement Noncash Consideration
LicensingAgreementNoncashConsideration
|
0 | usd |
CY2021 | zyme |
Licensing Agreement Noncash Consideration
LicensingAgreementNoncashConsideration
|
0 | usd |
CY2020 | zyme |
Licensing Agreement Noncash Consideration
LicensingAgreementNoncashConsideration
|
218000 | usd |
CY2022 | us-gaap |
Business Combination Contingent Consideration Arrangements Change In Amount Of Contingent Consideration Liability1
BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1
|
-250000 | usd |
CY2021 | us-gaap |
Business Combination Contingent Consideration Arrangements Change In Amount Of Contingent Consideration Liability1
BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1
|
213000 | usd |
CY2020 | us-gaap |
Business Combination Contingent Consideration Arrangements Change In Amount Of Contingent Consideration Liability1
BusinessCombinationContingentConsiderationArrangementsChangeInAmountOfContingentConsiderationLiability1
|
307000 | usd |
CY2022 | us-gaap |
Unrealized Gain Loss On Investments
UnrealizedGainLossOnInvestments
|
0 | usd |
CY2021 | us-gaap |
Unrealized Gain Loss On Investments
UnrealizedGainLossOnInvestments
|
167000 | usd |
CY2020 | us-gaap |
Unrealized Gain Loss On Investments
UnrealizedGainLossOnInvestments
|
0 | usd |
CY2022 | us-gaap |
Foreign Currency Transaction Gain Loss Unrealized
ForeignCurrencyTransactionGainLossUnrealized
|
1956000 | usd |
CY2021 | us-gaap |
Foreign Currency Transaction Gain Loss Unrealized
ForeignCurrencyTransactionGainLossUnrealized
|
433000 | usd |
CY2020 | us-gaap |
Foreign Currency Transaction Gain Loss Unrealized
ForeignCurrencyTransactionGainLossUnrealized
|
453000 | usd |
CY2022 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
17509000 | usd |
CY2021 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
266000 | usd |
CY2020 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
13107000 | usd |
CY2022 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
2059000 | usd |
CY2021 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
15792000 | usd |
CY2020 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
3519000 | usd |
CY2022 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
26479000 | usd |
CY2021 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
16477000 | usd |
CY2020 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
7618000 | usd |
CY2022 | zyme |
Increase Decrease In Operating Lease Liabilities
IncreaseDecreaseInOperatingLeaseLiabilities
|
-3736000 | usd |
CY2021 | zyme |
Increase Decrease In Operating Lease Liabilities
IncreaseDecreaseInOperatingLeaseLiabilities
|
-26000 | usd |
CY2020 | zyme |
Increase Decrease In Operating Lease Liabilities
IncreaseDecreaseInOperatingLeaseLiabilities
|
-1140000 | usd |
CY2022 | us-gaap |
Increase Decrease In Income Taxes
IncreaseDecreaseInIncomeTaxes
|
840000 | usd |
CY2021 | us-gaap |
Increase Decrease In Income Taxes
IncreaseDecreaseInIncomeTaxes
|
0 | usd |
CY2020 | us-gaap |
Increase Decrease In Income Taxes
IncreaseDecreaseInIncomeTaxes
|
0 | usd |
CY2022 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
144109000 | usd |
CY2021 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-192451000 | usd |
CY2020 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-151403000 | usd |
CY2022 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
107534000 | usd |
CY2021 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
0 | usd |
CY2020 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
300910000 | usd |
CY2022 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
|
255000 | usd |
CY2021 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
|
6428000 | usd |
CY2020 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans Including Stock Options
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
|
7111000 | usd |
CY2022 | zyme |
Proceeds From Issuance Of Shares Under Employee Share Purchase Plan
ProceedsFromIssuanceOfSharesUnderEmployeeSharePurchasePlan
|
1403000 | usd |
CY2021 | zyme |
Proceeds From Issuance Of Shares Under Employee Share Purchase Plan
ProceedsFromIssuanceOfSharesUnderEmployeeSharePurchasePlan
|
2070000 | usd |
CY2020 | zyme |
Proceeds From Issuance Of Shares Under Employee Share Purchase Plan
ProceedsFromIssuanceOfSharesUnderEmployeeSharePurchasePlan
|
1111000 | usd |
CY2022 | zyme |
Payments Of Deferred Financing Fees
PaymentsOfDeferredFinancingFees
|
596000 | usd |
CY2021 | zyme |
Payments Of Deferred Financing Fees
PaymentsOfDeferredFinancingFees
|
470000 | usd |
CY2020 | zyme |
Payments Of Deferred Financing Fees
PaymentsOfDeferredFinancingFees
|
113000 | usd |
CY2022 | us-gaap |
Finance Lease Principal Payments
FinanceLeasePrincipalPayments
|
14000 | usd |
CY2021 | us-gaap |
Finance Lease Principal Payments
FinanceLeasePrincipalPayments
|
17000 | usd |
CY2020 | us-gaap |
Finance Lease Principal Payments
FinanceLeasePrincipalPayments
|
41000 | usd |
CY2022 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
108582000 | usd |
CY2021 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
8011000 | usd |
CY2020 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
308978000 | usd |
CY2022 | us-gaap |
Payments For Proceeds From Short Term Investments
PaymentsForProceedsFromShortTermInvestments
|
40724000 | usd |
CY2021 | us-gaap |
Payments For Proceeds From Short Term Investments
PaymentsForProceedsFromShortTermInvestments
|
-157881000 | usd |
CY2020 | us-gaap |
Payments For Proceeds From Short Term Investments
PaymentsForProceedsFromShortTermInvestments
|
-13325000 | usd |
CY2022 | us-gaap |
Payments To Acquire Longterm Investments
PaymentsToAcquireLongtermInvestments
|
0 | usd |
CY2021 | us-gaap |
Payments To Acquire Longterm Investments
PaymentsToAcquireLongtermInvestments
|
0 | usd |
CY2020 | us-gaap |
Payments To Acquire Longterm Investments
PaymentsToAcquireLongtermInvestments
|
50500000 | usd |
CY2022 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
8150000 | usd |
CY2021 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
12404000 | usd |
CY2020 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
4310000 | usd |
CY2022 | us-gaap |
Payments To Acquire Intangible Assets
PaymentsToAcquireIntangibleAssets
|
4975000 | usd |
CY2021 | us-gaap |
Payments To Acquire Intangible Assets
PaymentsToAcquireIntangibleAssets
|
881000 | usd |
CY2020 | us-gaap |
Payments To Acquire Intangible Assets
PaymentsToAcquireIntangibleAssets
|
1955000 | usd |
CY2022 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-53849000 | usd |
CY2021 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
144596000 | usd |
CY2020 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-43440000 | usd |
CY2022 | us-gaap |
Effect Of Exchange Rate On Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
203000 | usd |
CY2021 | us-gaap |
Effect Of Exchange Rate On Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
-325000 | usd |
CY2020 | us-gaap |
Effect Of Exchange Rate On Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
-550000 | usd |
CY2022 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
199045000 | usd |
CY2021 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
-40169000 | usd |
CY2020 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
113585000 | usd |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
201867000 | usd |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
242036000 | usd |
CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
128451000 | usd |
CY2022Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
400912000 | usd |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
201867000 | usd |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
242036000 | usd |
CY2022 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
72000 | usd |
CY2021 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
24609000 | usd |
CY2020 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
2407000 | usd |
CY2022 | us-gaap |
Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
|
957000 | usd |
CY2021 | us-gaap |
Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
|
1933000 | usd |
CY2020 | us-gaap |
Capital Expenditures Incurred But Not Yet Paid
CapitalExpendituresIncurredButNotYetPaid
|
130000 | usd |
CY2022 | us-gaap |
Nature Of Operations
NatureOfOperations
|
Nature of Operations<div style="margin-top:6pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Zymeworks Inc. (the “Company” or “Zymeworks”) is a clinical-stage biopharmaceutical company dedicated to the development of next-generation multifunctional biotherapeutics. Zymeworks BC Inc. (previously known as "Zymeworks Inc.") was incorporated on September 8, 2003 under the laws of the Canada Business Corporations Act. On October 22, 2003, the Company was registered as an extra-provincial company under the Company Act (British Columbia). On May 2, 2017, the Company continued under the Business Corporations Act (British Columbia).</span></div><div style="margin-top:12pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Since its inception, the Company has devoted substantially all of its resources to research and development activities, including developing its therapeutic platforms and identifying and developing potential product candidates by undertaking preclinical studies and clinical trials. The Company supports these activities through general and administrative support, as well as by raising capital, conducting business planning and protecting its intellectual property. </span></div><div style="margin-top:12pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">On July 15, 2022, the Company announced its intention to become a Delaware corporation, subject to receipt of necessary shareholder, stock exchange, and court approvals (the "Redomicile Transactions"). The Redomicile Transactions were completed on October 13, 2022. On October 13, 2022, the Company changed its name to Zymeworks BC Inc. Unless the context otherwise requires or otherwise expressly states, all references in the accompanying consolidated financial statements to “Zymeworks,” the “Company,” “we,” “us” and “our” (i) for periods until completion of the Redomicile Transactions, refer to Zymeworks BC Inc. and its subsidiaries and (ii) for periods after completion of the Redomicile Transactions, refer to Zymeworks Inc. (formerly known as Zymeworks Delaware Inc.) and its subsidiaries. </span></div>To effect the Redomicile Transactions, the Company conducted a share exchange, pursuant to which holders of the Company's common shares exchanged their common shares in the Company for shares of common stock of Zymeworks Inc. (formerly known as Zymeworks Delaware Inc.) or, at their election with respect to all or a portion of their common shares in the Company and subject to applicable eligibility criteria and an overall cap, exchangeable shares (the “Exchangeable Shares”) in the capital of a newly formed indirect subsidiary of Zymeworks Inc. A special meeting of Company security holders was held on October 7, 2022 to approve the Redomicile Transactions. The Redomicile Transactions were governed by a transaction agreement dated July 14, 2022, as restated and amended on August 18, 2022 (the “Restated and Amended Transaction Agreement”), by and among the Company and its direct or indirect subsidiaries Zymeworks Inc., Zymeworks CallCo ULC and Zymeworks ExchangeCo Ltd., including a plan of arrangement included as Exhibit A to the Restated and Amended Transaction Agreement (the “Plan of Arrangement”). | |
CY2022 | us-gaap |
Use Of Estimates
UseOfEstimates
|
<div style="margin-top:12pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-style:italic;font-weight:700;line-height:120%">Use of Estimates</span></div><div style="margin-top:6pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The preparation of consolidated financial statements in accordance with U.S. GAAP requires the Company to make estimates and judgments in certain circumstances that affect the reported amounts of assets, liabilities, revenue and expenses, and related disclosure of contingent assets and liabilities. On an ongoing basis, the Company evaluates its estimates, most notably those related to revenue recognition including estimated timing of completion of performance obligations required to meet revenue recognition criteria, accrual of expenses including clinical and preclinical study expense accruals, stock-based compensation, valuation allowance for deferred taxes, benefits under the Scientific Research and Experimental Development (“SR&ED”) program, and other contingencies. Management bases its estimates on historical experience and on various other assumptions that it believes to be reasonable under the circumstances. Actual results could differ from these estimates.</span></div> | |
CY2022 | us-gaap |
Number Of Operating Segments
NumberOfOperatingSegments
|
1 | segment |
CY2022 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
124341000 | usd |
CY2021 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
-211843000 | usd |
CY2020 | us-gaap |
Net Income Loss Available To Common Stockholders Basic
NetIncomeLossAvailableToCommonStockholdersBasic
|
-180552000 | usd |
CY2022 | zyme |
Fair Value Option Adjustment For Change In Fair Value Of Liability Classified Stock Options
FairValueOptionAdjustmentForChangeInFairValueOfLiabilityClassifiedStockOptions
|
-231000 | usd |
CY2022 | us-gaap |
Goodwill Impairment Loss
GoodwillImpairmentLoss
|
0 | usd |
CY2021 | zyme |
Fair Value Option Adjustment For Change In Fair Value Of Liability Classified Stock Options
FairValueOptionAdjustmentForChangeInFairValueOfLiabilityClassifiedStockOptions
|
-28534000 | usd |
CY2020 | zyme |
Fair Value Option Adjustment For Change In Fair Value Of Liability Classified Stock Options
FairValueOptionAdjustmentForChangeInFairValueOfLiabilityClassifiedStockOptions
|
0 | usd |
CY2022 | us-gaap |
Net Income Loss Available To Common Stockholders Diluted
NetIncomeLossAvailableToCommonStockholdersDiluted
|
124110000 | usd |
CY2021 | us-gaap |
Net Income Loss Available To Common Stockholders Diluted
NetIncomeLossAvailableToCommonStockholdersDiluted
|
-240377000 | usd |
CY2020 | us-gaap |
Net Income Loss Available To Common Stockholders Diluted
NetIncomeLossAvailableToCommonStockholdersDiluted
|
-180552000 | usd |
CY2022 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
65194775 | shares |
CY2021 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
51553869 | shares |
CY2020 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
50382497 | shares |
CY2022 | us-gaap |
Incremental Common Shares Attributable To Share Based Payment Arrangements
IncrementalCommonSharesAttributableToShareBasedPaymentArrangements
|
53535 | shares |
CY2021 | us-gaap |
Incremental Common Shares Attributable To Share Based Payment Arrangements
IncrementalCommonSharesAttributableToShareBasedPaymentArrangements
|
0 | shares |
CY2020 | us-gaap |
Incremental Common Shares Attributable To Share Based Payment Arrangements
IncrementalCommonSharesAttributableToShareBasedPaymentArrangements
|
0 | shares |
CY2022 | zyme |
Incremental Common Shares Attributable To Dilutive Effect Of Share Based Payment Arrangements Liability Classified
IncrementalCommonSharesAttributableToDilutiveEffectOfShareBasedPaymentArrangementsLiabilityClassified
|
874 | shares |
CY2021 | zyme |
Incremental Common Shares Attributable To Dilutive Effect Of Share Based Payment Arrangements Liability Classified
IncrementalCommonSharesAttributableToDilutiveEffectOfShareBasedPaymentArrangementsLiabilityClassified
|
577727 | shares |
CY2020 | zyme |
Incremental Common Shares Attributable To Dilutive Effect Of Share Based Payment Arrangements Liability Classified
IncrementalCommonSharesAttributableToDilutiveEffectOfShareBasedPaymentArrangementsLiabilityClassified
|
0 | shares |
CY2022 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
65249184 | shares |
CY2021 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
52131596 | shares |
CY2020 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
50382497 | shares |
CY2022 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
1.91 | |
CY2021 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-4.11 | |
CY2020 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-3.58 | |
CY2022 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
1.90 | |
CY2021 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-4.61 | |
CY2020 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-3.58 | |
CY2022 | us-gaap |
Impairment Of Intangible Assets Excluding Goodwill
ImpairmentOfIntangibleAssetsExcludingGoodwill
|
0 | usd |
CY2021 | us-gaap |
Impairment Of Intangible Assets Excluding Goodwill
ImpairmentOfIntangibleAssetsExcludingGoodwill
|
0 | usd |
CY2020 | us-gaap |
Impairment Of Intangible Assets Excluding Goodwill
ImpairmentOfIntangibleAssetsExcludingGoodwill
|
0 | usd |
CY2022 | us-gaap |
Number Of Reporting Units
NumberOfReportingUnits
|
1 | reportingunit |
CY2022Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
38012000 | usd |
CY2021Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
36844000 | usd |
CY2022Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
13299000 | usd |
CY2021Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
14061000 | usd |
CY2022Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
24713000 | usd |
CY2021Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
22783000 | usd |
CY2022 | us-gaap |
Depreciation
Depreciation
|
6220000 | usd |
CY2021 | us-gaap |
Depreciation
Depreciation
|
3739000 | usd |
CY2020 | us-gaap |
Depreciation
Depreciation
|
3355000 | usd |
CY2022Q4 | us-gaap |
Finite Lived Intangible Assets Gross
FiniteLivedIntangibleAssetsGross
|
22927000 | usd |
CY2021Q4 | us-gaap |
Finite Lived Intangible Assets Gross
FiniteLivedIntangibleAssetsGross
|
17719000 | usd |
CY2022Q4 | us-gaap |
Finite Lived Intangible Assets Accumulated Amortization
FiniteLivedIntangibleAssetsAccumulatedAmortization
|
14172000 | usd |
CY2021Q4 | us-gaap |
Finite Lived Intangible Assets Accumulated Amortization
FiniteLivedIntangibleAssetsAccumulatedAmortization
|
13881000 | usd |
CY2022Q4 | us-gaap |
Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
|
8755000 | usd |
CY2021Q4 | us-gaap |
Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
|
3838000 | usd |
CY2022 | us-gaap |
Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
|
1015000 | usd |
CY2021 | us-gaap |
Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
|
2793000 | usd |
CY2020 | us-gaap |
Amortization Of Intangible Assets
AmortizationOfIntangibleAssets
|
4160000 | usd |
CY2022Q4 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Next Twelve Months
FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths
|
2702000 | usd |
CY2022Q4 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Year Two
FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo
|
2683000 | usd |
CY2022Q4 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Year Three
FiniteLivedIntangibleAssetsAmortizationExpenseYearThree
|
2259000 | usd |
CY2022Q4 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Year Four
FiniteLivedIntangibleAssetsAmortizationExpenseYearFour
|
427000 | usd |
CY2022Q4 | us-gaap |
Finite Lived Intangible Assets Amortization Expense Year Five
FiniteLivedIntangibleAssetsAmortizationExpenseYearFive
|
213000 | usd |
CY2022Q4 | zyme |
Finite Lived Intangible Asset Expected Amortization
FiniteLivedIntangibleAssetExpectedAmortization
|
8284000 | usd |
CY2022Q4 | us-gaap |
Accounts Payable Trade Current
AccountsPayableTradeCurrent
|
7863000 | usd |
CY2021Q4 | us-gaap |
Accounts Payable Trade Current
AccountsPayableTradeCurrent
|
5174000 | usd |
CY2022Q4 | zyme |
Accrued Research Expenses Current
AccruedResearchExpensesCurrent
|
39358000 | usd |
CY2021Q4 | zyme |
Accrued Research Expenses Current
AccruedResearchExpensesCurrent
|
50963000 | usd |
CY2022Q4 | us-gaap |
Sales And Excise Tax Payable Current
SalesAndExciseTaxPayableCurrent
|
16244000 | usd |
CY2021Q4 | us-gaap |
Sales And Excise Tax Payable Current
SalesAndExciseTaxPayableCurrent
|
0 | usd |
CY2022Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
14365000 | usd |
CY2022Q4 | us-gaap |
Other Accrued Liabilities Noncurrent
OtherAccruedLiabilitiesNoncurrent
|
682000 | usd |
CY2021Q4 | us-gaap |
Finance Lease Liability Noncurrent
FinanceLeaseLiabilityNoncurrent
|
100000 | usd |
CY2021Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
3346000 | usd |
CY2022Q4 | zyme |
Accrued Legal And Professional Fees Current
AccruedLegalAndProfessionalFeesCurrent
|
7799000 | usd |
CY2021Q4 | zyme |
Accrued Legal And Professional Fees Current
AccruedLegalAndProfessionalFeesCurrent
|
1064000 | usd |
CY2022Q4 | us-gaap |
Other Accounts Payable And Accrued Liabilities
OtherAccountsPayableAndAccruedLiabilities
|
1839000 | usd |
CY2021Q4 | us-gaap |
Other Accounts Payable And Accrued Liabilities
OtherAccountsPayableAndAccruedLiabilities
|
2242000 | usd |
CY2022Q4 | us-gaap |
Accounts Payable And Accrued Liabilities Current
AccountsPayableAndAccruedLiabilitiesCurrent
|
87468000 | usd |
CY2021Q4 | us-gaap |
Accounts Payable And Accrued Liabilities Current
AccountsPayableAndAccruedLiabilitiesCurrent
|
62789000 | usd |
CY2022Q4 | us-gaap |
Business Combination Contingent Consideration Liability Noncurrent
BusinessCombinationContingentConsiderationLiabilityNoncurrent
|
1248000 | usd |
CY2021Q4 | us-gaap |
Business Combination Contingent Consideration Liability Noncurrent
BusinessCombinationContingentConsiderationLiabilityNoncurrent
|
1498000 | usd |
CY2022Q4 | zyme |
Liabilities From In Licensing Agreements
LiabilitiesFromInLicensingAgreements
|
1047000 | usd |
CY2021Q4 | zyme |
Liabilities From In Licensing Agreements
LiabilitiesFromInLicensingAgreements
|
1150000 | usd |
CY2022Q4 | us-gaap |
Finance Lease Liability Noncurrent
FinanceLeaseLiabilityNoncurrent
|
124000 | usd |
CY2021Q4 | us-gaap |
Other Accrued Liabilities Noncurrent
OtherAccruedLiabilitiesNoncurrent
|
0 | usd |
CY2022Q4 | us-gaap |
Liabilities Other Than Longterm Debt Noncurrent
LiabilitiesOtherThanLongtermDebtNoncurrent
|
3101000 | usd |
CY2021Q4 | us-gaap |
Liabilities Other Than Longterm Debt Noncurrent
LiabilitiesOtherThanLongtermDebtNoncurrent
|
2748000 | usd |
CY2022Q4 | zyme |
All Classes Of Stock Shares Authorized
AllClassesOfStockSharesAuthorized
|
1000000000 | shares |
CY2022Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
900000000 | shares |
CY2022Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.00001 | |
CY2021Q4 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
100000000 | shares |
CY2022Q4 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
100000000 | shares |
CY2022Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.00001 | |
CY2021Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.00001 | |
CY2022Q4 | us-gaap |
Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
|
1 | shares |
CY2022Q4 | us-gaap |
Preferred Stock Shares Issued
PreferredStockSharesIssued
|
1 | shares |
CY2022Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.00001 | |
CY2021Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.00001 | |
CY2022Q4 | us-gaap |
Temporary Equity Shares Outstanding
TemporaryEquitySharesOutstanding
|
1424533 | shares |
CY2019Q2 | us-gaap |
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
|
0.0001 | |
CY2022Q3 | zyme |
Warrants Exercised During Period
WarrantsExercisedDuringPeriod
|
3787737 | shares |
CY2021Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares
|
773593 | shares |
CY2021Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue
|
27.97 | |
CY2022Q3 | us-gaap |
Stock Issued During Period Shares Conversion Of Convertible Securities
StockIssuedDuringPeriodSharesConversionOfConvertibleSecurities
|
3787675 | shares |
CY2022Q3 | us-gaap |
Stock Issued During Period Value Conversion Of Convertible Securities
StockIssuedDuringPeriodValueConversionOfConvertibleSecurities
|
57858000 | usd |
CY2022Q2 | us-gaap |
Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
|
74.00 | |
CY2022 | zyme |
Share Based Payment Arrangement Individual Penalty Threshold Percentage
ShareBasedPaymentArrangementIndividualPenaltyThresholdPercentage
|
0.10 | |
CY2022 | zyme |
Share Based Payment Arrangement Institutional Investors Penalty Threshold Percentage
ShareBasedPaymentArrangementInstitutionalInvestorsPenaltyThresholdPercentage
|
0.20 | |
CY2018Q2 | zyme |
Maximum Number Of Common Shares Reserved For Issuance
MaximumNumberOfCommonSharesReservedForIssuance
|
5686097 | shares |
CY2018Q1 | zyme |
Common Stock Shares Issuable Upon Exercise Of Stock Option
CommonStockSharesIssuableUponExerciseOfStockOption
|
3686097 | shares |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
|
3205132 | shares |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant
ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant
|
952632 | shares |
CY2018Q2 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Outstanding Stock Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardPercentageOfOutstandingStockMaximum
|
0.20 | |
CY2022 | zyme |
Share Based Compensation Arrangement By Share Based Payment Award Exercisable Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardExercisablePeriod
|
P10Y | |
CY2022 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
255000 | usd |
CY2021 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
6428000 | usd |
CY2020 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
7111000 | usd |
CY2021Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue
|
21.98 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
|
917035 | shares |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
5.80 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
4.28 | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedNumberOfShares
|
355428 | shares |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue
|
19.61 | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedWeightedAverageGrantDateFairValue
|
14.47 | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Options Forfeited Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedNumberOfShares
|
562660 | shares |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Options Forfeited Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedWeightedAverageGrantDateFairValue
|
19.83 | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Options Forfeited Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedOptionsForfeitedWeightedAverageGrantDateFairValue
|
14.64 | |
CY2022Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Number Of Shares
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedNumberOfShares
|
772540 | shares |
CY2022Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue
|
11.40 | |
CY2022Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Nonvested Weighted Average Grant Date Fair Value
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsNonvestedWeightedAverageGrantDateFairValue
|
8.41 | |
CY2022 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
9516000 | usd |
CY2022Q4 | zyme |
Derivative Liability Classified Stock Options And Espp
DerivativeLiabilityClassifiedStockOptionsAndESPP
|
3261000 | usd |
CY2021 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
38275000 | usd |
CY2021Q4 | zyme |
Derivative Liability Classified Stock Options And Espp
DerivativeLiabilityClassifiedStockOptionsAndESPP
|
27517000 | usd |
CY2020 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
26945000 | usd |
CY2020Q4 | zyme |
Derivative Liability Classified Stock Options And Espp
DerivativeLiabilityClassifiedStockOptionsAndESPP
|
2171000 | usd |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Weighted Average Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate
|
0.772 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Weighted Average Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate
|
0.803 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Weighted Average Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsWeightedAverageVolatilityRate
|
0.768 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
|
0.0212 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
|
0.0102 | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
|
0.0066 | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
|
P5Y11M4D | |
CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
|
P6Y18D | |
CY2020 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
|
P6Y14D | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
53000 | usd |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
10998000 | usd |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
19446000 | usd |
CY2022 | zyme |
Share Based Compensation By Share Based Payment Award Unamortized Compensation Expense
ShareBasedCompensationByShareBasedPaymentAwardUnamortizedCompensationExpense
|
13879000 | usd |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1
|
P1Y6M | |
CY2022 | zyme |
Accrued Investment Tax Credit
AccruedInvestmentTaxCredit
|
0 | usd |
CY2022 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
412482000 | usd |
CY2021 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
26680000 | usd |
CY2020 | us-gaap |
Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
|
38951000 | usd |
CY2022Q4 | us-gaap |
Contract With Customer Asset Net
ContractWithCustomerAssetNet
|
3000000 | usd |
CY2021Q4 | us-gaap |
Contract With Customer Asset Net
ContractWithCustomerAssetNet
|
0 | usd |
CY2022Q4 | us-gaap |
Contract With Customer Liability
ContractWithCustomerLiability
|
32941000 | usd |
CY2021Q4 | us-gaap |
Contract With Customer Liability
ContractWithCustomerLiability
|
32941000 | usd |
CY2022Q4 | us-gaap |
Contract With Customer Liability Current
ContractWithCustomerLiabilityCurrent
|
2353000 | usd |
CY2021Q4 | us-gaap |
Contract With Customer Liability Current
ContractWithCustomerLiabilityCurrent
|
0 | usd |
CY2021 | us-gaap |
Current Income Tax Expense Benefit
CurrentIncomeTaxExpenseBenefit
|
437000 | usd |
CY2020 | us-gaap |
Current Income Tax Expense Benefit
CurrentIncomeTaxExpenseBenefit
|
292000 | usd |
CY2022 | us-gaap |
Foreign Currency Transaction Gain Loss Before Tax
ForeignCurrencyTransactionGainLossBeforeTax
|
1152000 | usd |
CY2021 | us-gaap |
Foreign Currency Transaction Gain Loss Before Tax
ForeignCurrencyTransactionGainLossBeforeTax
|
1191000 | usd |
CY2020 | us-gaap |
Foreign Currency Transaction Gain Loss Before Tax
ForeignCurrencyTransactionGainLossBeforeTax
|
1683000 | usd |
CY2022 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
-42000 | usd |
CY2021 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
118000 | usd |
CY2020 | us-gaap |
Other Nonoperating Income Expense
OtherNonoperatingIncomeExpense
|
-35000 | usd |
CY2022 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
1110000 | usd |
CY2021 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
1309000 | usd |
CY2020 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
1648000 | usd |
CY2022 | us-gaap |
Current Income Tax Expense Benefit
CurrentIncomeTaxExpenseBenefit
|
8953000 | usd |
CY2022 | us-gaap |
Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
|
1940000 | usd |
CY2021 | us-gaap |
Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
|
-953000 | usd |
CY2020 | us-gaap |
Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
|
137000 | usd |
CY2022 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
10893000 | usd |
CY2021 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-516000 | usd |
CY2020 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
429000 | usd |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Settlements State And Local
EffectiveIncomeTaxRateReconciliationTaxSettlementsStateAndLocal
|
0.21 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Settlements State And Local
EffectiveIncomeTaxRateReconciliationTaxSettlementsStateAndLocal
|
0.21 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Settlements State And Local
EffectiveIncomeTaxRateReconciliationTaxSettlementsStateAndLocal
|
0.21 | |
CY2022 | us-gaap |
Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
|
28429000 | usd |
CY2021 | us-gaap |
Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
|
-44620000 | usd |
CY2020 | us-gaap |
Income Tax Reconciliation Income Tax Expense Benefit At Federal Statutory Income Tax Rate
IncomeTaxReconciliationIncomeTaxExpenseBenefitAtFederalStatutoryIncomeTaxRate
|
-37821000 | usd |
CY2022 | us-gaap |
Income Tax Reconciliation Nondeductible Expense
IncomeTaxReconciliationNondeductibleExpense
|
9745000 | usd |
CY2021 | us-gaap |
Income Tax Reconciliation Nondeductible Expense
IncomeTaxReconciliationNondeductibleExpense
|
798000 | usd |
CY2020 | us-gaap |
Income Tax Reconciliation Nondeductible Expense
IncomeTaxReconciliationNondeductibleExpense
|
7149000 | usd |
CY2022 | us-gaap |
Income Tax Reconciliation Foreign Income Tax Rate Differential
IncomeTaxReconciliationForeignIncomeTaxRateDifferential
|
8365000 | usd |
CY2021 | us-gaap |
Income Tax Reconciliation Foreign Income Tax Rate Differential
IncomeTaxReconciliationForeignIncomeTaxRateDifferential
|
-12175000 | usd |
CY2020 | us-gaap |
Income Tax Reconciliation Foreign Income Tax Rate Differential
IncomeTaxReconciliationForeignIncomeTaxRateDifferential
|
-8949000 | usd |
CY2022 | us-gaap |
Income Tax Reconciliation Prior Year Income Taxes
IncomeTaxReconciliationPriorYearIncomeTaxes
|
826000 | usd |
CY2021 | us-gaap |
Income Tax Reconciliation Prior Year Income Taxes
IncomeTaxReconciliationPriorYearIncomeTaxes
|
33000 | usd |
CY2020 | us-gaap |
Income Tax Reconciliation Prior Year Income Taxes
IncomeTaxReconciliationPriorYearIncomeTaxes
|
441000 | usd |
CY2022 | us-gaap |
Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance
IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-33526000 | usd |
CY2021 | us-gaap |
Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance
IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
60260000 | usd |
CY2020 | us-gaap |
Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance
IncomeTaxReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
48411000 | usd |
CY2022 | zyme |
Income Tax Reconciliation Nondeductible Expense Share Issuance Costs In Equity
IncomeTaxReconciliationNondeductibleExpenseShareIssuanceCostsInEquity
|
0 | usd |
CY2021 | zyme |
Income Tax Reconciliation Nondeductible Expense Share Issuance Costs In Equity
IncomeTaxReconciliationNondeductibleExpenseShareIssuanceCostsInEquity
|
-2000 | usd |
CY2020 | zyme |
Income Tax Reconciliation Nondeductible Expense Share Issuance Costs In Equity
IncomeTaxReconciliationNondeductibleExpenseShareIssuanceCostsInEquity
|
-5385000 | usd |
CY2022 | us-gaap |
Income Tax Reconciliation Tax Credits Research
IncomeTaxReconciliationTaxCreditsResearch
|
3238000 | usd |
CY2021 | us-gaap |
Income Tax Reconciliation Tax Credits Research
IncomeTaxReconciliationTaxCreditsResearch
|
5096000 | usd |
CY2020 | us-gaap |
Income Tax Reconciliation Tax Credits Research
IncomeTaxReconciliationTaxCreditsResearch
|
4067000 | usd |
CY2022 | us-gaap |
Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
|
292000 | usd |
CY2021 | us-gaap |
Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
|
286000 | usd |
CY2020 | us-gaap |
Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
|
650000 | usd |
CY2022 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
10893000 | usd |
CY2021 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
-516000 | usd |
CY2020 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
429000 | usd |
CY2022Q4 | zyme |
Deferred Tax Assets Non Capital Loss Carry Forwards
DeferredTaxAssetsNonCapitalLossCarryForwards
|
84948000 | usd |
CY2021Q4 | zyme |
Deferred Tax Assets Non Capital Loss Carry Forwards
DeferredTaxAssetsNonCapitalLossCarryForwards
|
123554000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Deferred Income
DeferredTaxAssetsDeferredIncome
|
8893000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Deferred Income
DeferredTaxAssetsDeferredIncome
|
8894000 | usd |
CY2022Q4 | zyme |
Deferred Tax Assets Share Issue Costs
DeferredTaxAssetsShareIssueCosts
|
4549000 | usd |
CY2021Q4 | zyme |
Deferred Tax Assets Share Issue Costs
DeferredTaxAssetsShareIssueCosts
|
6058000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Property Plant And Equipment
DeferredTaxAssetsPropertyPlantAndEquipment
|
565000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Property Plant And Equipment
DeferredTaxAssetsPropertyPlantAndEquipment
|
1219000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Goodwill And Intangible Assets
DeferredTaxAssetsGoodwillAndIntangibleAssets
|
5930000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Goodwill And Intangible Assets
DeferredTaxAssetsGoodwillAndIntangibleAssets
|
2911000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
39957000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
35401000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Contingencies
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies
|
404000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Reserves And Accruals Contingencies
DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsContingencies
|
421000 | usd |
CY2022Q4 | zyme |
Deferred Tax Assets Stock Options
DeferredTaxAssetsStockOptions
|
4344000 | usd |
CY2021Q4 | zyme |
Deferred Tax Assets Stock Options
DeferredTaxAssetsStockOptions
|
4330000 | usd |
CY2022Q4 | zyme |
Deferred Tax Assets Operating Lease Liability
DeferredTaxAssetsOperatingLeaseLiability
|
7008000 | usd |
CY2021Q4 | zyme |
Deferred Tax Assets Operating Lease Liability
DeferredTaxAssetsOperatingLeaseLiability
|
7871000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Other
DeferredTaxAssetsOther
|
302000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Other
DeferredTaxAssetsOther
|
351000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
156900000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
191010000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Liabilities Property Plant And Equipment
DeferredTaxLiabilitiesPropertyPlantAndEquipment
|
967000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Liabilities Property Plant And Equipment
DeferredTaxLiabilitiesPropertyPlantAndEquipment
|
1085000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Liabilities Goodwill And Intangible Assets Intangible Assets
DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets
|
4759000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Liabilities Goodwill And Intangible Assets Intangible Assets
DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets
|
4760000 | usd |
CY2022Q4 | zyme |
Deferred Tax Liabilities Operating Lease Right Of Use Assets
DeferredTaxLiabilitiesOperatingLeaseRightOfUseAssets
|
5758000 | usd |
CY2021Q4 | zyme |
Deferred Tax Liabilities Operating Lease Right Of Use Assets
DeferredTaxLiabilitiesOperatingLeaseRightOfUseAssets
|
6685000 | usd |
CY2022Q4 | zyme |
Deferred Tax Liabilities Outside Basis Difference
DeferredTaxLiabilitiesOutsideBasisDifference
|
1788000 | usd |
CY2021Q4 | zyme |
Deferred Tax Liabilities Outside Basis Difference
DeferredTaxLiabilitiesOutsideBasisDifference
|
1573000 | usd |
CY2022Q4 | us-gaap |
Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
|
13272000 | usd |
CY2021Q4 | us-gaap |
Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
|
14103000 | usd |
CY2022Q4 | zyme |
Deferred Tax Assets Liabilities Before Valuation Allowance
DeferredTaxAssetsLiabilitiesBeforeValuationAllowance
|
143628000 | usd |
CY2021Q4 | zyme |
Deferred Tax Assets Liabilities Before Valuation Allowance
DeferredTaxAssetsLiabilitiesBeforeValuationAllowance
|
176907000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
144071000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
175410000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Liabilities
DeferredTaxLiabilities
|
443000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
1497000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Net
DeferredTaxAssetsNet
|
1345000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Net
DeferredTaxAssetsNet
|
3070000 | usd |
CY2022Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
3322000 | usd |
CY2022Q4 | us-gaap |
Deferred Income Tax Liabilities Net
DeferredIncomeTaxLiabilitiesNet
|
1788000 | usd |
CY2021Q4 | us-gaap |
Deferred Income Tax Liabilities Net
DeferredIncomeTaxLiabilitiesNet
|
1573000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Liabilities
DeferredTaxLiabilities
|
443000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
1497000 | usd |
CY2022Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
314700000 | usd |
CY2021Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
457600000 | usd |
CY2022Q4 | us-gaap |
Operating Loss Carryforwards
OperatingLossCarryforwards
|
314653000 | usd |
CY2021Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
3063000 | usd |
CY2020Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
3063000 | usd |
CY2019Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
3063000 | usd |
CY2022 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions
|
0 | usd |
CY2021 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions
|
0 | usd |
CY2020 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromPriorPeriodTaxPositions
|
0 | usd |
CY2022 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
|
0 | usd |
CY2021 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
|
0 | usd |
CY2020 | us-gaap |
Unrecognized Tax Benefits Increases Resulting From Current Period Tax Positions
UnrecognizedTaxBenefitsIncreasesResultingFromCurrentPeriodTaxPositions
|
0 | usd |
CY2022Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
3063000 | usd |
CY2021Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
3063000 | usd |
CY2020Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
3063000 | usd |
CY2022Q4 | us-gaap |
Unrecognized Tax Benefits That Would Impact Effective Tax Rate
UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate
|
0 | usd |
CY2020Q4 | us-gaap |
Unrecognized Tax Benefits That Would Impact Effective Tax Rate
UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate
|
0 | usd |
CY2021Q4 | us-gaap |
Unrecognized Tax Benefits That Would Impact Effective Tax Rate
UnrecognizedTaxBenefitsThatWouldImpactEffectiveTaxRate
|
0 | usd |
CY2021Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
1310000 | usd |
CY2022Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
24667000 | usd |
CY2021Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
30923000 | usd |
CY2022Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
27989000 | usd |
CY2021Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
32233000 | usd |
CY2022Q4 | us-gaap |
Finance Lease Liability Current
FinanceLeaseLiabilityCurrent
|
16000 | usd |
CY2021Q4 | us-gaap |
Finance Lease Liability Current
FinanceLeaseLiabilityCurrent
|
22000 | usd |
CY2022Q4 | us-gaap |
Finance Lease Liability Noncurrent
FinanceLeaseLiabilityNoncurrent
|
124000 | usd |
CY2021Q4 | us-gaap |
Finance Lease Liability Noncurrent
FinanceLeaseLiabilityNoncurrent
|
100000 | usd |
CY2022Q4 | us-gaap |
Finance Lease Liability
FinanceLeaseLiability
|
140000 | usd |
CY2021Q4 | us-gaap |
Finance Lease Liability
FinanceLeaseLiability
|
122000 | usd |
CY2022Q4 | zyme |
Lease Liability
LeaseLiability
|
28129000 | usd |
CY2021Q4 | zyme |
Lease Liability
LeaseLiability
|
32355000 | usd |
CY2022 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
4471000 | usd |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Rolling Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextRollingTwelveMonths
|
4435000 | usd |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due In Rolling Year Two
LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearTwo
|
4493000 | usd |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due In Rolling Year Three
LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearThree
|
4611000 | usd |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due In Rolling Year Four
LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFour
|
4589000 | usd |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due In Rolling Year Five
LesseeOperatingLeaseLiabilityPaymentsDueInRollingYearFive
|
3357000 | usd |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due After Rolling Year Five
LesseeOperatingLeaseLiabilityPaymentsDueAfterRollingYearFive
|
11653000 | usd |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
33138000 | usd |
CY2022Q4 | us-gaap |
Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
|
5149000 | usd |
CY2022Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
27989000 | usd |
CY2022Q4 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P7Y9M18D | |
CY2022 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
7795000 | usd |
CY2021 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
5658000 | usd |
CY2020 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
3595000 | usd |
CY2022 | zyme |
Fixed Lease Payment
FixedLeasePayment
|
6609000 | usd |
CY2021 | zyme |
Fixed Lease Payment
FixedLeasePayment
|
5323000 | usd |
CY2020 | zyme |
Fixed Lease Payment
FixedLeasePayment
|
3156000 | usd |
CY2022 | us-gaap |
Variable Lease Payment
VariableLeasePayment
|
1186000 | usd |
CY2021 | us-gaap |
Variable Lease Payment
VariableLeasePayment
|
335000 | usd |
CY2020 | us-gaap |
Variable Lease Payment
VariableLeasePayment
|
439000 | usd |
CY2022 | us-gaap |
Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
|
0 | usd |
CY2021 | us-gaap |
Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
|
0 | usd |
CY2022Q4 | us-gaap |
Assets Fair Value Disclosure
AssetsFairValueDisclosure
|
291609000 | usd |
CY2022Q4 | us-gaap |
Financial Liabilities Fair Value Disclosure
FinancialLiabilitiesFairValueDisclosure
|
1248000 | usd |
CY2021Q4 | us-gaap |
Assets Fair Value Disclosure
AssetsFairValueDisclosure
|
112128000 | usd |
CY2021Q4 | us-gaap |
Financial Liabilities Fair Value Disclosure
FinancialLiabilitiesFairValueDisclosure
|
1498000 | usd |
CY2021Q4 | zyme |
Contingent Consideration Liability Fair Value Disclosure
ContingentConsiderationLiabilityFairValueDisclosure
|
1498000 | usd |
CY2022 | zyme |
Contingent Consideration Fair Value Adjustments
ContingentConsiderationFairValueAdjustments
|
0 | usd |
CY2022 | zyme |
Contingent Consideration Liability Fair Value Disclosure Transfers
ContingentConsiderationLiabilityFairValueDisclosureTransfers
|
250000 | usd |
CY2022Q4 | zyme |
Contingent Consideration Liability Fair Value Disclosure
ContingentConsiderationLiabilityFairValueDisclosure
|
1248000 | usd |
CY2020Q4 | zyme |
Contingent Consideration Liability Fair Value Disclosure
ContingentConsiderationLiabilityFairValueDisclosure
|
1285000 | usd |
CY2021 | zyme |
Contingent Consideration Fair Value Adjustments
ContingentConsiderationFairValueAdjustments
|
213000 | usd |
CY2021 | zyme |
Contingent Consideration Liability Fair Value Disclosure Transfers
ContingentConsiderationLiabilityFairValueDisclosureTransfers
|
0 | usd |
CY2021Q4 | zyme |
Contingent Consideration Liability Fair Value Disclosure
ContingentConsiderationLiabilityFairValueDisclosure
|
1498000 | usd |
CY2022 | us-gaap |
Concentration Risk Credit Risk Financial Instrument Maximum Exposure
ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure
|
33400000 | usd |
CY2021 | us-gaap |
Concentration Risk Credit Risk Financial Instrument Maximum Exposure
ConcentrationRiskCreditRiskFinancialInstrumentMaximumExposure
|
15614000 | usd |
CY2022Q4 | zyme |
Net Monetary Assets Denominated In Foreign Currency
NetMonetaryAssetsDenominatedInForeignCurrency
|
-1593000 | usd |
CY2022Q4 | zyme |
Net Monetary Assets Denominated In Foreign Currency
NetMonetaryAssetsDenominatedInForeignCurrency
|
-2144000 | cad |
CY2022 | us-gaap |
Restructuring And Related Cost Number Of Positions Eliminated Period Percent
RestructuringAndRelatedCostNumberOfPositionsEliminatedPeriodPercent
|
0.25 | |
CY2022Q4 | us-gaap |
Restructuring Reserve
RestructuringReserve
|
678000 | usd |