Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.
Reported portfolio value by quarter (27 quarters reported)
$465M in Q4 2019 → $288M now. Hover for any quarter.
As reported for the quarter ended June 30, 2026. Activity is the change in share count since the prior quarter's filing.
| Holding | % of portfolio | Activity | Shares | Value |
|---|---|---|---|---|
| Maplight Therapeutics Inc | 11.8% | Unchanged | 950,011 | $34M |
| Tyra Biosciences Inc | 11.4% | Unchanged | 1,029,298 | $32.9M |
| Entrada Therapeutics Inc | 10.4% | Unchanged | 4,056,379 | $29.9M |
| Pharvaris N V | 9.6% | Unchanged | 797,600 | $27.6M |
| Camp4 Therapeutics Corp | 8.9% | Unchanged | 5,869,091 | $25.6M |
| Artiva Biotherapeutics Inc | 7.9% | Unchanged | 2,353,304 | $22.8M |
| Tectonic Therapeutic Inc | 7.2% | Unchanged | 606,660 | $20.9M |
| Zentalis Pharmaceuticals Inc | 6.7% | Unchanged | 3,947,913 | $19.1M |
| CT Celldex Therapeutics Inc New | 6.4% | Unchanged | 497,270 | $18.5M |
| Eyepoint Inc | 5.2% | Unchanged | 1,050,000 | $15M |
| Biohaven Ltd | 3.8% | Unchanged | 738,972 | $11M |
| Surrozen Inc | 2.4% | Trimmed 30% | 271,250 | $7.04M |
| Skye Bioscience Inc | 2.3% | Unchanged | 9,681,763 | $6.71M |
| AO Alx Oncology Hldgs Inc | 2.2% | Unchanged | 3,057,325 | $6.33M |
| Protara Therapeutics Inc | 1.8% | Unchanged | 1,369,782 | $5.23M |
| Silence Therapeutics PLC | 1.8% | Unchanged | 476,200 | $5.23M |
What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.
quarter ended June 30, 2026 · filed August 14, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Erasca Inc | Exited | −3,485,971 | −$56.4M | — |
| Centessa Pharmaceuticals PLC | Exited | −580,945 | −$23.1M | — |
| Gh Research PLC | Exited | −572,665 | −$8.05M | — |
| Surrozen Inc | Trimmed | −116,250 | −$3.02M | 2.4% |
| Rallybio Corp | Exited | −291,788 | −$2.62M | — |
quarter ended March 31, 2026 · filed May 15, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Erasca Inc | Trimmed | −1,919,433 | −$31.1M | 15.7% |
| Viridian Therapeutics Inc | Exited | −736,595 | −$22.9M | — |
| Enliven Therapeutics Inc | Exited | −772,477 | −$11.9M | — |
| AO Alx Oncology Hldgs Inc | New | +3,057,325 | +$6.13M | 1.7% |
| Rallybio Corp | New | +291,788 | +$2.62M | 0.7% |
| Rallybio Corp | Exited | −3,630,724 | −$2.49M | — |
quarter ended December 31, 2025 · filed February 17, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Maplight Therapeutics Inc | New | +950,011 | +$16.7M | 5.2% |
| Dianthus Therapeutics Inc | Exited | −365,053 | −$14.4M | — |
| PP Praxis Precision Medicines I | Exited | −170,000 | −$9.01M | — |
| Zentalis Pharmaceuticals Inc | Added | +3,457,913 | +$4.67M | 1.7% |
| Protara Therapeutics Inc | Added | +569,782 | +$3.04M | 2.3% |
| Alector Inc | Exited | −995,841 | −$2.95M | — |
| Biohaven Ltd | Added | +260,000 | +$2.94M | 2.6% |
| Centessa Pharmaceuticals PLC | Trimmed | −100,000 | −$2.5M | 4.6% |
| Adverum Biotechnologies Inc | Exited | −541,666 | −$2.45M | — |
| Tyra Biosciences Inc | Added | +90,000 | +$2.37M | 8.5% |
Showing the 10 largest of 14 changes.
quarter ended September 30, 2025 · filed November 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Dianthus Therapeutics Inc | Trimmed | −619,672 | −$24.4M | 5.3% |
| Moonlake Immunotherapeutics | Exited | −282,313 | −$13.3M | — |
| Vor Biopharma Inc | Exited | −6,361,723 | −$10.3M | — |
| Camp4 Therapeutics Corp | Added | +2,941,176 | +$8.82M | 6.4% |
| Viking Therapeutics Inc | Exited | −189,593 | −$5.02M | — |
| Scpharmaceuticals Inc | Exited | −1,200,647 | −$4.57M | — |
| Centessa Pharmaceuticals PLC | Trimmed | −150,000 | −$3.64M | 6.0% |
| Skye Bioscience Inc | Trimmed | −231,405 | −$909K | 13.9% |
| Mersana Therapeutics Inc | New | +52,200 | +$405K | 0.1% |
| Mersana Therapeutics Inc | Exited | −1,305,000 | −$386K | — |
Showing the 10 largest of 11 changes.
quarter ended June 30, 2025 · filed August 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Enliven Therapeutics Inc | Trimmed | −550,000 | −$11M | 6.0% |
| Anaptysbio Inc | Exited | −357,733 | −$6.65M | — |
| Cidara Therapeutics Inc | Exited | −56,725 | −$1.22M | — |
| Dianthus Therapeutics Inc | Trimmed | −42,986 | −$801K | 7.1% |
| Entrada Therapeutics Inc | Trimmed | −100,000 | −$672K | 11.1% |
quarter ended March 31, 2025 · filed May 15, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Enliven Therapeutics Inc | Trimmed | −307,288 | −$6.05M | 9.8% |
| Akero Therapeutics Inc | Exited | −165,000 | −$4.59M | — |
| Surrozen Inc | New | +310,000 | +$3.61M | 1.4% |
| Tectonic Therapeutic Inc | Trimmed | −85,000 | −$1.51M | 3.4% |
quarter ended December 31, 2024 · filed February 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Camp4 Therapeutics Corp | New | +2,927,915 | +$15.3M | 3.6% |
| PP Praxis Precision Medicines I | Trimmed | −170,000 | −$13.1M | 3.1% |
| Centessa Pharmaceuticals PLC | Trimmed | −454,055 | −$7.61M | 3.3% |
| Cogent Biosciences Inc | Exited | −561,854 | −$6.07M | — |
| Akero Therapeutics Inc | New | +165,000 | +$4.59M | 1.1% |
| Dianthus Therapeutics Inc | Trimmed | −203,908 | −$4.45M | 5.3% |
| Protara Therapeutics Inc | New | +800,000 | +$4.22M | 1.0% |
| Enliven Therapeutics Inc | Trimmed | −122,409 | −$2.75M | 8.8% |
| Tectonic Therapeutic Inc | Trimmed | −49,864 | −$2.3M | 6.6% |
| Viking Therapeutics Inc | Trimmed | −47,967 | −$1.93M | 1.8% |
Showing the 10 largest of 11 changes.
quarter ended September 30, 2024 · filed November 14, 2024
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Artiva Biotherapeutics Inc | New | +2,353,304 | +$36.4M | 7.5% |
| Enliven Therapeutics Inc | Trimmed | −858,701 | −$21.9M | 9.2% |
| EP Eyepoint Pharmaceuticals Inc | Added | +1,000,000 | +$7.99M | 1.7% |
| Q32 Bio Inc | Exited | −251,994 | −$4.52M | — |
| Cogent Biosciences Inc | Trimmed | −228,586 | −$2.47M | 1.3% |
| Skye Bioscience Inc | Trimmed | −266,337 | −$1.04M | 8.0% |
| Centessa Pharmaceuticals PLC | Added | +40,000 | +$640K | 4.2% |
| Biohaven Ltd | Added | +9,000 | +$450K | 4.9% |
| Dianthus Therapeutics Inc | Trimmed | −1,346 | −$36.9K | 7.0% |
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