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Allostery Investments LP

Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.

Portfolio value
—
Positions
1
Quarter ended
September 30, 2025
Filed
November 14, 2025

Reported portfolio value by quarter (4 quarters reported)

$95.7M —
Q4 24 Q1 25 Q2 25 Q3 25

$95.7M in Q4 2024 → — now. Hover for any quarter.

Holdings

As reported for the quarter ended September 30, 2025. Activity is the change in share count since the prior quarter's filing.

Holding % of portfolio Activity Shares Value
0 0 NaN% New 0 —

Timeline of changes

What changed each quarter, from the filings' own share counts. Largest moves first; most recent 3 quarters.

Q3 2025

quarter ended September 30, 2025 · filed November 14, 2025

Company Action Shares changed Value of change % of portfolio
Abivax Sa Exited −167,350 −$1.28M —
Akero Therapeutics Inc Exited −22,500 −$1.2M —
Amylyx Pharmaceuticals Inc Exited −120,119 −$770K —
Centessa Pharmaceuticals PLC Exited −52,500 −$690K —
Evolus Inc Exited −60,000 −$553K —
Rezolute Inc Exited −119,294 −$532K —
Merus N V Exited −9,000 −$473K —
Kalvista Pharmaceuticals Inc Exited −40,000 −$452K —
Fulcrum Therapeutics Inc Exited −40,353 −$278K —
Apogee Therapeutics Inc Exited −6,000 −$261K —

Showing the 10 largest of 21 changes.

Q2 2025

quarter ended June 30, 2025 · filed August 14, 2025

Company Action Shares changed Value of change % of portfolio
Abivax Sa Trimmed −932,304 −$7.13M 16.3%
Merus N V Trimmed −115,657 −$6.08M 6.0%
Kalvista Pharmaceuticals Inc Trimmed −418,302 −$4.73M 5.8%
Apogee Therapeutics Inc Trimmed −104,000 −$4.52M 3.3%
Centessa Pharmaceuticals PLC Trimmed −330,024 −$4.34M 8.8%
Alkermes PLC Exited −115,000 −$3.8M —
AT Aerovate Therapeutics Inc Exited −1,421,568 −$3.57M —
Bridgebio Pharma Inc Trimmed −76,000 −$3.28M 2.2%
Evolus Inc Trimmed −352,754 −$3.25M 7.0%
Zura Bio Ltd Exited −2,329,384 −$3M —

Showing the 10 largest of 46 changes.

Q1 2025

quarter ended March 31, 2025 · filed May 15, 2025

Company Action Shares changed Value of change % of portfolio
SS SPDR Ser Tr Exited −175,000 −$15.8M —
IQ Invesco Qqq Tr Exited −25,000 −$12.8M —
IT Ishares Tr Exited −100,000 −$8.73M —
Merus N V Added +102,922 +$4.33M 7.6%
Abivax Sa Added +508,401 +$3.18M 9.9%
Bridgebio Pharma Inc New +80,000 +$2.77M 4.0%
Apellis Pharmaceuticals Inc Exited −80,000 −$2.55M —
Springworks Therapeutics Inc New +52,500 +$2.32M 3.3%
Tg Therapeutics Inc Exited −75,000 −$2.26M —
Beam Therapeutics Inc New +92,754 +$1.81M 2.6%

Showing the 10 largest of 47 changes.

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