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Super Investors Avidity Partners Management LP
AP

Avidity Partners Management LP

Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.

Portfolio value
$624M
Positions
45
Quarter ended
June 30, 2026
Filed
August 14, 2026

Reported portfolio value by quarter (27 quarters reported)

$4.92B $159M
Q4 19 Q2 21 Q4 22 Q2 24 Q4 25 Q2 26

$159M in Q4 2019 → $624M now. Hover for any quarter.

Holdings

As reported for the quarter ended June 30, 2026. Activity is the change in share count since the prior quarter's filing.

Holding % of portfolio Activity Shares Value
Dianthus Therapeutics Inc 32.8% Trimmed 50% 2,104,184 $205M
Cg Oncology Inc 15.9% Added 8.5% 1,398,948 $99.4M
Oruka Therapeutics Inc 11.6% Trimmed 50% 760,424 $72.4M
Jade Biosciences Inc 6.1% Trimmed 39% 1,700,708 $37.8M
Enliven Therapeutics Inc 4.5% Trimmed 31% 550,000 $27.9M
Perspective Therapeutics Inc 3.4% Trimmed 48% 6,299,999 $21.5M
Aktis Oncology Inc 2.5% Trimmed 48% 484,200 $15.6M
PT Palvella Therapeutics Inc Ne 1.7% Trimmed 50% 70,000 $10.7M
MM Mobia Med Inc 1.7% New 798,282 $10.7M
Repligen Corp 1.7% Trimmed 50% 77,800 $10.6M
Immunic Inc 1.6% New 669,941 $10.3M
SH Senseonics Hldgs Inc 1.5% New 1,600,000 $9.09M
Karyopharm Therapeutics Inc 1.4% Trimmed 0.3% 924,487 $9.03M
TP Teva Pharmaceutical Inds Ltd 1.1% Trimmed 69% 200,000 $6.78M
Dexcom Inc 1.1% Trimmed 47% 100,000 $6.74M
Tempus Ai Inc 1.0% Added 17% 105,000 $6.08M
Medtronic PLC 0.9% Trimmed 65% 70,000 $5.48M
Vir Biotechnology Inc 0.8% Trimmed 67% 519,300 $5.29M
Structure Therapeutics Inc 0.8% Added 26% 98,000 $5.26M
Encompass Health Corp 0.7% Trimmed 50% 42,000 $4.25M
Tenax Therapeutics Inc 0.6% Trimmed 45% 265,934 $3.87M
Nuvectis Pharma Inc 0.6% New 200,000 $3.68M
Insulet Corp 0.6% Added 140% 24,000 $3.65M
Boston Scientific Corp 0.5% Trimmed 33% 80,000 $3.41M
Satellos Bioscience Inc 0.5% Trimmed 50% 387,769 $3.01M
Alamar Biosciences Inc 0.5% New 110,000 $2.98M
Context Therapeutics Inc 0.4% Trimmed 50% 4,998,267 $2.77M
Gilead Sciences Inc 0.4% Trimmed 50% 20,000 $2.53M
CR Charles Riv Labs Intl Inc 0.4% Unchanged 10,000 $2.27M
Phathom Pharmaceuticals Inc 0.3% Trimmed 60% 200,000 $2.17M
AP Avalyn Pharmaceuticals Inc 0.3% New 60,000 $1.98M
Kailera Therapeutics Inc 0.3% New 80,000 $1.76M
Genmab A/s 0.2% Trimmed 50% 50,000 $1.37M
Intellia Therapeutics Inc 0.2% Trimmed 50% 75,000 $1.27M
Corvus Pharmaceuticals Inc 0.2% Trimmed 65% 80,000 $1.2M
Oddity Tech Ltd 0.2% Trimmed 50% 70,000 $1.06M
Scynexis Inc 0.2% New 260,206 $1.06M
Evommune Inc 0.2% New 75,000 $997K
Abbott Laboratories 0.1% Unchanged 10,000 $907K
Bridgebio Pharma Inc 0.1% Unchanged 10,000 $745K
Peloton Interactive Inc 0.1% Trimmed 75% 100,000 $591K
Legend Biotech Corp 0.1% Unchanged 15,000 $433K
BO Bridgebio Oncology Therapeut 0.1% Trimmed 50% 43,853 $334K
Savara Inc 0.0% Unchanged 50,000 $308K
Trevi Therapeutics Inc 0.0% Trimmed 50% 6,660 $124K

Timeline of changes

What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.

Q2 2026

quarter ended June 30, 2026 · filed August 14, 2026

Company Action Shares changed Value of change % of portfolio
Dianthus Therapeutics Inc Trimmed −2,104,184 −$205M 32.8%
Oruka Therapeutics Inc Trimmed −760,424 −$72.4M 11.6%
Jade Biosciences Inc Trimmed −1,100,708 −$24.5M 6.1%
Perspective Therapeutics Inc Trimmed −5,799,999 −$19.8M 3.4%
TP Teva Pharmaceutical Inds Ltd Trimmed −450,100 −$15.2M 1.1%
Aktis Oncology Inc Trimmed −452,932 −$14.6M 2.5%
Immunic Inc Exited −7,369,352 −$13.9M —
Enliven Therapeutics Inc Trimmed −250,000 −$12.7M 4.5%
Vir Biotechnology Inc Trimmed −1,050,000 −$10.7M 0.8%
PT Palvella Therapeutics Inc Ne Trimmed −70,000 −$10.7M 1.7%

Showing the 10 largest of 56 changes.

Q1 2026

quarter ended March 31, 2026 · filed May 28, 2026

Company Action Shares changed Value of change % of portfolio
Dianthus Therapeutics Inc Added +2,104,184 +$181M 38.6%
Oruka Therapeutics Inc Added +860,424 +$50.5M 9.5%
Perspective Therapeutics Inc Added +8,889,265 +$35.9M 5.2%
Jade Biosciences Inc Added +1,400,708 +$26.9M 5.8%
Enliven Therapeutics Inc Added +659,700 +$26.5M 3.4%
Aktis Oncology Inc New +937,132 +$17.2M 1.8%
PT Palvella Therapeutics Inc Ne Added +120,700 +$15.3M 1.9%
Vir Biotechnology Inc New +1,569,300 +$14.8M 1.6%
Cg Oncology Inc Trimmed −183,751 −$12.4M 9.3%
Repligen Corp Added +105,300 +$12.4M 2.0%

Showing the 10 largest of 67 changes.

Q4 2025

quarter ended December 31, 2025 · filed February 13, 2026

Company Action Shares changed Value of change % of portfolio
Dianthus Therapeutics Inc Trimmed −1,100,000 −$45.3M 25.0%
Natera Inc Trimmed −58,600 −$13.4M 0.8%
Bristol-myers Squibb Co Exited −257,600 −$11.6M —
Danaher Corporation Trimmed −37,700 −$8.63M 1.1%
Alnylam Pharmaceuticals Inc New +21,000 +$8.35M 2.4%
Medtronic PLC Trimmed −83,000 −$7.97M 3.0%
Metsera Inc Exited −140,500 −$7.35M —
Thermo Fisher Scientific Inc Trimmed −12,200 −$7.07M 1.1%
Unitedhealth Group Inc Exited −17,800 −$6.15M —
Icon PLC New +33,100 +$6.03M 1.7%

Showing the 10 largest of 50 changes.

Q3 2025

quarter ended September 30, 2025 · filed November 14, 2025

Company Action Shares changed Value of change % of portfolio
Dianthus Therapeutics Inc Added +1,461,282 +$57.5M 28.7%
Natera Inc Trimmed −128,900 −$20.7M 2.6%
Tenet Healthcare Corp Exited −106,000 −$18.7M —
Dexcom Inc Exited −210,500 −$18.4M —
Medtronic PLC New +190,600 +$18.2M 4.1%
Hinge Health Inc Exited −322,344 −$16.7M —
Exact Sciences Corp Trimmed −281,400 −$15.4M 0.9%
Boston Scientific Corp Trimmed −157,500 −$15.4M 3.7%
IS Intuitive Surgival Inc Exited −27,100 −$14.7M —
Genmab A/s Trimmed −401,900 −$12.3M 1.7%

Showing the 10 largest of 67 changes.

Q2 2025

quarter ended June 30, 2025 · filed August 14, 2025

Company Action Shares changed Value of change % of portfolio
Humana Inc Exited −80,000 −$21.2M —
Hinge Health Inc New +322,344 +$16.7M 3.3%
Regeneron Pharmaceuticals Exited −25,400 −$16.1M —
IS Intuitive Surgival Inc New +27,100 +$14.7M 2.9%
Natera Inc Added +80,100 +$13.5M 6.7%
Cg Oncology Inc Added +519,000 +$13.5M 7.8%
Genmab A/s New +650,000 +$13.4M 2.7%
Repligen Corp New +106,500 +$13.2M 2.6%
Glaukos Corp Exited −134,000 −$13.2M —
Humana Inc Trimmed −53,400 −$13.1M 1.3%

Showing the 10 largest of 77 changes.

Q1 2025

quarter ended March 31, 2025 · filed May 15, 2025

Company Action Shares changed Value of change % of portfolio
Intuitive Surgical Inc Exited −64,800 −$33.8M —
Mirum Pharmaceuticals Inc Trimmed −626,200 −$28.2M 0.3%
AH Acadia Healthcare Company In Exited −658,000 −$26.1M —
Humana Inc New +80,000 +$21.2M 4.0%
Dianthus Therapeutics Inc Trimmed −1,152,098 −$20.9M 5.9%
Kymera Therapeutics Inc Exited −500,000 −$20.1M —
Jazz Pharmaceuticals PLC Trimmed −154,500 −$19.2M 1.9%
Boston Scientific Corp Trimmed −179,000 −$18.1M 6.5%
Neurocrine Biosciences Inc Trimmed −134,700 −$14.9M 1.8%
Natera Inc Trimmed −104,600 −$14.8M 3.2%

Showing the 10 largest of 82 changes.

Q4 2024

quarter ended December 31, 2024 · filed February 14, 2025

Company Action Shares changed Value of change % of portfolio
Natera Inc Trimmed −332,600 −$52.7M 3.5%
Intuitive Surgical Inc Trimmed −83,400 −$43.5M 3.3%
Boston Scientific Corp Trimmed −447,000 −$39.9M 4.5%
Neurocrine Biosciences Inc Trimmed −239,600 −$32.7M 3.0%
Glaukos Corp Trimmed −174,900 −$26.2M 2.5%
Insmed Inc Trimmed −359,200 −$24.8M 1.6%
Illumina Inc Trimmed −182,300 −$24.4M 1.4%
Jazz Pharmaceuticals PLC Trimmed −196,500 −$24.2M 2.8%
Neumora Therapeutics Inc. Exited −1,800,000 −$23.8M —
Biomarin Pharmaceutical Inc Exited −320,000 −$22.5M —

Showing the 10 largest of 86 changes.

Q3 2024

quarter ended September 30, 2024 · filed November 14, 2024

Company Action Shares changed Value of change % of portfolio
The Cigna Group Exited −184,500 −$61M —
Alnylam Pharmaceuticals Inc Exited −222,000 −$53.9M —
Unitedhealth Group Inc New +87,400 +$51.1M 2.6%
Regeneron Pharmaceuticals Exited −48,000 −$50.4M —
Avantor Inc Trimmed −1,851,000 −$47.9M 1.6%
Intuitive Surgical Inc Trimmed −96,800 −$47.6M 3.7%
Humana Inc New +129,700 +$41.1M 2.1%
Merck & Co Inc Exited −325,000 −$40.2M —
Arvinas Inc Trimmed −1,490,845 −$36.7M 1.9%
Abbvie Inc Trimmed −177,800 −$35.1M 1.0%

Showing the 10 largest of 94 changes.

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