Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.
Reported portfolio value by quarter (51 quarters reported)
$118M in Q4 2013 → $1.65B now. Hover for any quarter.
As reported for the quarter ended June 30, 2026. Activity is the change in share count since the prior quarter's filing.
| Holding | % of portfolio | Activity | Shares | Value |
|---|---|---|---|---|
| Neogenomics Inc | 10.9% | Added 26% | 12,279,523 | $179M |
| Si-bone Inc | 8.1% | Added 52% | 8,127,985 | $133M |
| Axogen Inc | 7.7% | Trimmed 31% | 2,748,361 | $127M |
| Apogee Therapeutics Inc | 7.5% | Added 61% | 930,289 | $123M |
| Palvella Therapeutics Inc | 7.2% | Trimmed 21% | 771,901 | $118M |
| Twist Bioscience Corporation | 4.6% | Trimmed 17% | 727,933 | $74.9M |
| Enliven Therapeutics Inc | 4.2% | Added 574% | 1,360,750 | $69.1M |
| Guardant Health | 4.0% | Added 58% | 441,586 | $66.3M |
| 908 Devices Inc | 3.3% | Added 3.5% | 6,282,804 | $54.7M |
| Amylyx Pharmaceuticals Inc | 3.3% | Trimmed 5.2% | 3,023,256 | $54.3M |
| Genedx Holdings Corp | 3.3% | Added 223% | 783,923 | $53.8M |
| Simulations Plus Inc | 3.1% | Added 6.1% | 2,792,677 | $51.1M |
| Tandem Diabetes Care Inc | 3.1% | Added 157% | 3,383,553 | $51.1M |
| Crinetics Pharmaceuticals Inc | 3.1% | Added 25% | 1,360,866 | $50.9M |
| Neuropace Inc | 2.8% | Added 16% | 2,861,167 | $45.5M |
| Edgewise Therapeutics Inc | 2.7% | Added 9.3% | 1,095,171 | $44.5M |
| AB Anaptys Bio Inc | 2.4% | Added 2.9% | 582,004 | $39.3M |
| Trevi Therapeutics Inc | 2.4% | New | 2,097,215 | $39.1M |
| Septerna Inc | 2.0% | Added 31% | 963,260 | $32.3M |
| Trisalus Life Sciences Inc | 1.8% | Added 29% | 6,552,491 | $29.8M |
| TT Tectonic Therapeutics Inc | 1.7% | Added 24% | 800,726 | $27.5M |
| Health Catalyst Inc | 1.5% | Trimmed 0.5% | 12,810,861 | $25.5M |
| Butterfly Network Inc | 1.4% | Trimmed 0.7% | 2,642,404 | $22.2M |
| Establishment Labs Holdings | 1.3% | Trimmed 20% | 246,577 | $21.2M |
| Vaxcyte Inc | 1.2% | Added 143% | 345,157 | $20.1M |
| IT Irhythm Technologies | 1.2% | Trimmed 0.6% | 167,092 | $19.9M |
| Omnicell Inc | 1.1% | Trimmed 7.7% | 452,324 | $18.8M |
| Atricure Inc | 1.0% | Trimmed 22% | 567,838 | $15.9M |
| Koru Medical Systems Inc | 0.9% | Trimmed 10% | 3,387,902 | $14.2M |
| Tactile Systems Technology Inc | 0.8% | New | 462,562 | $13.8M |
| Rhythm Pharmaceuticals Inc | 0.6% | Trimmed 1.6% | 85,765 | $9.52M |
What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.
quarter ended June 30, 2026 · filed August 14, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Centessa Pharmaceuticals Limited | Exited | −1,560,991 | −$62M | — |
| Enliven Therapeutics Inc | Added | +1,158,883 | +$58.8M | 4.2% |
| Axogen Inc | Trimmed | −1,254,407 | −$57.9M | 7.7% |
| Apogee Therapeutics Inc | Added | +353,605 | +$46.9M | 7.5% |
| Si-bone Inc | Added | +2,774,795 | +$45.3M | 8.1% |
| Trevi Therapeutics Inc | New | +2,097,215 | +$39.1M | 2.4% |
| Neogenomics Inc | Added | +2,549,545 | +$37.2M | 10.9% |
| Genedx Holdings Corp | Added | +540,996 | +$37.1M | 3.3% |
| Palvella Therapeutics Inc | Trimmed | −208,857 | −$31.9M | 7.2% |
| Tandem Diabetes Care Inc | Added | +2,068,838 | +$31.2M | 3.1% |
Showing the 10 largest of 37 changes.
quarter ended March 31, 2026 · filed May 15, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Disc Medicine Inc | Exited | −523,167 | −$41.5M | — |
| Axogen Inc | Trimmed | −1,230,558 | −$40.8M | 11.9% |
| Madrigal Pharmaceuticals Inc | Exited | −66,831 | −$38.9M | — |
| Palvella Therapeutics Inc | Added | +271,617 | +$33.9M | 11.0% |
| Centessa Pharmaceuticals Limited | Trimmed | −717,949 | −$28.5M | 5.6% |
| Apogee Therapeutics Inc | Added | +291,693 | +$24.6M | 4.3% |
| Vera Therapeutics Inc | Trimmed | −555,770 | −$22.4M | 1.1% |
| Trisalus Life Sciences Inc | New | +5,066,827 | +$20.3M | 1.8% |
| TT Tectonic Therapeutics Inc | New | +647,743 | +$20M | 1.8% |
| Rhythm Pharmaceuticals Inc | Trimmed | −208,663 | −$18.1M | 0.7% |
Showing the 10 largest of 40 changes.
quarter ended December 31, 2025 · filed February 17, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Performant Healthcare Inc | Exited | −11,718,612 | −$90.6M | — |
| Si-bone Inc | Added | +3,115,001 | +$61.4M | 7.6% |
| Centessa Pharmaceuticals Limited | Trimmed | −1,356,876 | −$33.9M | 4.4% |
| Lenz Therapeutics Inc | Exited | −693,044 | −$32.3M | — |
| Madrigal Pharmaceuticals Inc | Added | +55,292 | +$32.2M | 3.0% |
| Wave Life Sciences Ltd | New | +1,853,851 | +$31.5M | 2.4% |
| Cidara Therapeutics Inc | Exited | −292,657 | −$28M | — |
| Tandem Diabetes Care Inc | New | +1,089,493 | +$23.9M | 1.8% |
| Disc Medicine Inc | Added | +291,981 | +$23.2M | 3.2% |
| Simulations Plus Inc | Added | +1,201,157 | +$21.9M | 2.7% |
Showing the 10 largest of 47 changes.
quarter ended September 30, 2025 · filed November 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| AB Anaptys Bio Inc | Trimmed | −2,549,432 | −$78.1M | 2.9% |
| Amylyx Pharmaceuticals Inc | New | +3,355,882 | +$45.6M | 4.3% |
| Palvella Therapeutics Inc | New | +541,544 | +$33.9M | 3.2% |
| Lenz Therapeutics Inc | New | +693,044 | +$32.3M | 3.0% |
| Neogenomics Inc | Added | +3,080,837 | +$23.8M | 7.2% |
| Axogen Inc | Added | +1,276,487 | +$22.8M | 9.8% |
| MN Merus Nv | New | +224,080 | +$21.1M | 2.0% |
| Rhythm Pharmaceuticals Inc | New | +180,484 | +$18.2M | 1.7% |
| Centessa Pharmaceuticals Limited | Trimmed | −657,595 | −$15.9M | 8.3% |
| Disc Medicine Inc | New | +231,186 | +$15.3M | 1.4% |
Showing the 10 largest of 47 changes.
quarter ended June 30, 2025 · filed August 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Organogenesis Holdings Inc | New | +6,777,163 | +$24.8M | 3.2% |
| AB Anaptys Bio Inc | Trimmed | −1,094,009 | −$24.3M | 10.2% |
| IT Irhythm Technologies | Trimmed | −137,691 | −$21.2M | 3.7% |
| Adma Biologics Inc | New | +952,096 | +$17.3M | 2.2% |
| Senseonics Holdings Inc | Added | +31,050,619 | +$14.8M | 2.2% |
| Vera Therapeutics Inc | Trimmed | −612,898 | −$14.4M | 1.7% |
| Xenon Pharmaceuticals | Trimmed | −439,537 | −$13.8M | 0.8% |
| Janux Therapeutics Inc | Trimmed | −509,228 | −$11.8M | 0.4% |
| Caris Life Sciences Inc | New | +443,043 | +$11.2M | 1.5% |
| Twist Bioscience Corporation | Trimmed | −273,666 | −$10.1M | 4.5% |
Showing the 10 largest of 45 changes.
quarter ended March 31, 2025 · filed May 15, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Paragon 28 Inc | Trimmed | −10,080,467 | −$132M | 0.7% |
| Anaptysbio Inc | Added | +3,764,720 | +$70M | 9.8% |
| Insmed Inc | Trimmed | −402,039 | −$30.7M | 0.6% |
| Neogenomics Inc | Added | +2,875,237 | +$27.3M | 6.5% |
| Edgewise Therapeutics Inc | Added | +1,071,651 | +$23.6M | 4.7% |
| Health Catalyst Inc | Added | +5,195,686 | +$23.5M | 5.4% |
| Pliant Therapeutics Inc | Exited | −1,681,110 | −$22.1M | — |
| Atricure Inc | Trimmed | −654,503 | −$21.1M | 4.8% |
| Neuropace Inc | New | +1,584,048 | +$19.5M | 2.2% |
| Xenon Pharmaceuticals Inc | Trimmed | −532,676 | −$17.9M | 2.4% |
Showing the 10 largest of 41 changes.
quarter ended December 31, 2024 · filed February 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Twist Bioscience Corporation | New | +1,226,255 | +$57M | 5.5% |
| IT Irhythm Technologies | New | +430,500 | +$38.8M | 3.7% |
| Insulet Corp | Trimmed | −125,261 | −$32.7M | 0.8% |
| Mimedx Group Inc | New | +3,343,861 | +$32.2M | 3.1% |
| Avid Bioservices Inc | Exited | −2,771,853 | −$31.5M | — |
| Tandem Diabetes Care Inc | Trimmed | −733,190 | −$26.4M | 1.0% |
| Evolent Health Inc | Trimmed | −2,244,641 | −$25.3M | 0.1% |
| Vera Therapeutics Inc | Added | +556,012 | +$23.5M | 5.1% |
| Bicycle Therapeutics PLC | Exited | −967,006 | −$21.9M | — |
| Edgewise Therapeutics Inc | New | +780,639 | +$20.8M | 2.0% |
Showing the 10 largest of 47 changes.
quarter ended September 30, 2024 · filed November 14, 2024
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Livanova PLC | Exited | −710,390 | −$38.9M | — |
| Avid Bioservices Inc | New | +2,771,853 | +$31.5M | 2.6% |
| Dyne Therapeutics Inc | Added | +874,852 | +$31.4M | 3.8% |
| RR R1 Rcm Inc | Exited | −2,464,809 | −$31M | — |
| Alphatec Holdings Inc | Trimmed | −5,189,972 | −$28.9M | 0.1% |
| Repligen Corp | New | +165,873 | +$24.7M | 2.1% |
| Evolent Health Inc | Added | +852,956 | +$24.1M | 5.4% |
| Natera Inc | Trimmed | −184,129 | −$23.4M | 2.0% |
| Kymera Therapeutics Inc | New | +406,348 | +$19.2M | 1.6% |
| Centessa Pharmaceuticals Limited | Added | +1,159,572 | +$18.5M | 7.9% |
Showing the 10 largest of 49 changes.
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