Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.
Reported portfolio value by quarter (6 quarters reported)
$430M in Q1 2025 → $2.11B now. Hover for any quarter.
As reported for the quarter ended June 30, 2026. Activity is the change in share count since the prior quarter's filing.
| Holding | % of portfolio | Activity | Shares | Value |
|---|---|---|---|---|
| Revolution Medicines Inc | 67.6% | Unchanged | 7,601,087 | $1.42B |
| PM Parabilis Medicines Inc | 6.1% | New | 4,663,176 | $128M |
| Relay Therapeutics Inc | 6.0% | Added 23% | 6,776,506 | $127M |
| Tyra Biosciences Inc | 5.4% | Trimmed 12% | 3,553,585 | $114M |
| Alumis Inc | 4.7% | Unchanged | 3,540,998 | $99.6M |
| Oric Pharmaceuticals Inc | 3.7% | Unchanged | 7,162,637 | $77.6M |
| Kymera Therapeutics Inc | 1.5% | Unchanged | 278,896 | $32M |
| Zymeworks Inc | 1.4% | Unchanged | 1,113,946 | $29.1M |
| Monte Rosa Therapeutics Inc | 0.9% | Added 150% | 761,153 | $18.4M |
| Avalo Therapeutics Inc | 0.8% | Added 108% | 1,122,713 | $17.1M |
| Cytomx Therapeutics Inc. | 0.8% | Unchanged | 4,449,932 | $16.7M |
| Silence Therapeutics PLC | 0.5% | Unchanged | 952,400 | $10.5M |
| Corvus Pharmaceuticals Inc | 0.3% | Unchanged | 450,000 | $6.72M |
| Context Therapeutics Inc | 0.2% | Unchanged | 7,419,355 | $4.11M |
| Engene Therapeutics Inc | 0.2% | New | 2,324,943 | $4.02M |
What changed each quarter, from the filings' own share counts. Largest moves first; most recent 5 quarters.
quarter ended June 30, 2026 · filed August 14, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Tango Therapeutics Inc | Exited | −7,266,081 | −$152M | — |
| PM Parabilis Medicines Inc | New | +4,663,176 | +$128M | 6.1% |
| Relay Therapeutics Inc | Added | +1,250,000 | +$23.4M | 6.0% |
| Cullinan Therapeutics Inc | Exited | −1,141,145 | −$16.2M | — |
| Tyra Biosciences Inc | Trimmed | −502,276 | −$16M | 5.4% |
| EH Engene Holdings Inc | Exited | −2,324,943 | −$15.8M | — |
| Monte Rosa Therapeutics Inc | Added | +456,916 | +$11.1M | 0.9% |
| Avalo Therapeutics Inc | Added | +583,319 | +$8.89M | 0.8% |
| Ars Pharmaceuticals Inc | Exited | −610,703 | −$4.9M | — |
| Engene Therapeutics Inc | New | +2,324,943 | +$4.02M | 0.2% |
quarter ended March 31, 2026 · filed May 15, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Cytomx Therapeutics Inc. | New | +4,449,932 | +$20.9M | 1.5% |
| Mersana Therapeutics Inc | Exited | −482,689 | −$14M | — |
| Alumis Inc | Added | +625,000 | +$13.8M | 5.5% |
| Relay Therapeutics Inc | Added | +825,000 | +$8.21M | 3.9% |
| Corvus Pharmaceuticals Inc | New | +450,000 | +$6.58M | 0.5% |
| EH Engene Holdings Inc | Added | +200,000 | +$1.36M | 1.1% |
| Monte Rosa Therapeutics Inc | Added | +25,000 | +$411K | 0.4% |
| Ars Pharmaceuticals Inc | Trimmed | −50,000 | −$402K | 0.3% |
quarter ended December 31, 2025 · filed February 17, 2026
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| EH Engene Holdings Inc | New | +2,124,943 | +$19.2M | 1.9% |
| Tango Therapeutics Inc | Added | +1,732,101 | +$15.3M | 6.2% |
| Arvinas Inc | Trimmed | −869,000 | −$10.3M | 0.6% |
| Relay Therapeutics Inc | Added | +855,097 | +$7.23M | 3.8% |
| Kymera Therapeutics Inc | Trimmed | −62,013 | −$4.83M | 2.1% |
| Monte Rosa Therapeutics Inc | New | +279,237 | +$4.38M | 0.4% |
| Boundless Bio Inc | Exited | −1,228,069 | −$1.51M | — |
quarter ended September 30, 2025 · filed November 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Cargo Therapeutics Inc | Exited | −2,642,502 | −$10.9M | — |
| Mersana Therapeutics Inc | New | +482,689 | +$3.75M | 0.6% |
| Mersana Therapeutics Inc | Exited | −12,067,246 | −$3.57M | — |
| Ars Pharmaceuticals Inc | Trimmed | −81,026 | −$814K | 1.0% |
quarter ended June 30, 2025 · filed August 14, 2025
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Oric Pharmaceuticals Inc | Added | +1,876,923 | +$19.1M | 13.8% |
| Kymera Therapeutics Inc | New | +340,909 | +$14.9M | 2.8% |
| Alumis Inc | Added | +1,439,000 | +$4.32M | 1.7% |
| Ars Pharmaceuticals Inc | Trimmed | −195,000 | −$3.4M | 2.4% |
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