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Super Investors Sio Capital Management, LLC
SC

Sio Capital Management, LLC

Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.

Portfolio value
$604M
Positions
59
Quarter ended
June 30, 2026
Filed
August 14, 2026

Reported portfolio value by quarter (47 quarters reported)

$697M $127M
Q4 14 Q2 17 Q4 19 Q2 22 Q4 24 Q2 26

$127M in Q4 2014 → $604M now. Hover for any quarter.

Holdings

As reported for the quarter ended June 30, 2026. Activity is the change in share count since the prior quarter's filing.

Holding % of portfolio Activity Shares Value
Anteris Technologies Global 9.0% Added 3.0% 5,545,984 $54.6M
Cencora Inc 8.1% Added 72% 173,588 $49.1M
Maximus Inc 6.4% Trimmed 7.0% 715,267 $38.5M
Allogene Therapeutics Inc 4.6% New 13,323,431 $27.7M
GM Globus Med Inc 3.9% New 301,816 $23.8M
Gsk PLC 3.8% Added 13% 436,700 $22.9M
Tyra Biosciences Inc 3.7% Added 15% 695,315 $22.2M
WH Waystar Hldg Corp 3.1% Trimmed 44% 925,834 $19M
SL Sellas Life Sciences Group I Put 3.0% New 1,230,700 $18.2M
Ideaya Biosciences Inc 3.0% New 480,383 $17.9M
Oruka Therapeutics Inc 2.8% Added 34% 177,118 $16.9M
The Cigna Group 2.6% New 57,750 $15.9M
Sanofi Sa 2.6% Added 52% 364,200 $15.5M
IP Icon Pub Ltd Co 2.5% Trimmed 71% 88,186 $15.3M
Viatris Inc 2.5% New 954,299 $15.2M
CC Cross Ctry Healthcare Inc 2.4% Unchanged 1,098,393 $14.5M
Rapport Therapeutics Inc 2.1% Trimmed 16% 307,657 $12.8M
Abbott Laboratories 1.9% Trimmed 31% 128,656 $11.7M
Celcuity Inc 1.9% Trimmed 43% 110,022 $11.5M
Zimmer Biomet Holdings Inc 1.9% Added 110% 131,445 $11.3M
Regeneron Pharmaceuticals 1.9% New 18,000 $11.2M
Bristol-myers Squibb Co 1.8% New 193,500 $11.1M
Medtronic PLC 1.8% New 142,500 $11.1M
Vir Biotechnology Inc 1.8% Trimmed 28% 1,075,274 $11M
SH Senseonics Hldgs Inc 1.5% Added 1276% 1,592,692 $9.05M
Eyepoint Inc 1.5% Trimmed 14% 623,130 $8.91M
Cybin Inc 1.4% New 1,300,000 $8.59M
Ani Pharmaceuticals Inc 1.3% Trimmed 63% 97,305 $8.05M
Protara Therapeutics Inc 1.2% Trimmed 2.4% 1,921,872 $7.34M
Relmada Therapeutics Inc 1.1% Added 4.0% 1,003,562 $6.94M
Tango Therapeutics Inc 1.1% New 208,500 $6.52M
Aquestive Therapeutics Inc 1.0% Trimmed 23% 1,486,175 $6.18M
Dianthus Therapeutics Inc 1.0% Trimmed 84% 59,254 $5.78M
Sionna Therapeutics Inc 0.9% Trimmed 57% 127,808 $5.62M
Ocular Therapeutix Inc 0.9% Trimmed 44% 539,493 $5.3M
Zenas Biopharma Inc 0.9% Trimmed 37% 208,557 $5.29M
Bright Minds Biosciences Inc 0.9% Trimmed 14% 73,952 $5.19M
Onkure Therapeutics Inc 0.8% Unchanged 1,078,965 $4.92M
Savara Inc 0.6% Added 0.6% 617,675 $3.8M
Pmv Pharmaceuticals Inc 0.6% Trimmed 14% 2,634,137 $3.53M
AH Aveanna Healthcare Hldgs Inc 0.5% New 369,036 $3.16M
Ovid Therapeutics Inc 0.4% Trimmed 20% 1,005,334 $2.7M
Immunome Inc 0.4% Trimmed 25% 124,168 $2.63M
Hims & Hers Health Inc Call 0.4% New 75,000 $2.6M
An2 Therapeutics Inc 0.4% Trimmed 19% 529,933 $2.56M
Serina Therapeutics Inc 0.3% Unchanged 1,000,000 $1.94M
Aligos Therapeutics Inc 0.3% Unchanged 327,237 $1.89M
Ibio Inc 0.3% Unchanged 904,268 $1.58M
Xilio Therapeutics Inc 0.2% Unchanged 152,464 $1.46M
Artivion Inc 0.2% New 48,481 $1.09M
BO Bridgebio Oncology Therapeut 0.2% Unchanged 130,628 $995K
Tela Bio Inc 0.1% Unchanged 636,300 $477K
AM Adagio Med Hldgs Inc 0.1% Trimmed 46% 698,989 $455K
NM Neuroone Med Technologies Co 0.0% New 82,767 $252K
Enveric Biosciences Inc 0.0% New 180,000 $248K
MM Modular Med Inc 0.0% Unchanged 26,190 $118K
QI Qt Imaging Hldgs Inc 0.0% New 15,236 $62K
Rocket Pharmaceuticals Inc 0.0% Unchanged 400,000 $1.48K
Humacyte Inc 0.0% Unchanged 49,998 $477

Timeline of changes

What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.

Q2 2026

quarter ended June 30, 2026 · filed August 14, 2026

Company Action Shares changed Value of change % of portfolio
IP Icon Pub Ltd Co Trimmed −218,172 −$37.9M 2.5%
Dianthus Therapeutics Inc Trimmed −310,791 −$30.3M 1.0%
Allogene Therapeutics Inc New +13,323,431 +$27.7M 4.6%
Corcept Therapeutics Inc Exited −674,759 −$27.2M —
Livanova PLC Exited −421,615 −$26.8M —
GM Globus Med Inc New +301,816 +$23.8M 3.9%
Cencora Inc Added +72,694 +$20.6M 8.1%
SL Sellas Life Sciences Group I New +1,230,700 +$18.2M 3.0%
Ideaya Biosciences Inc New +480,383 +$17.9M 3.0%
Embecta Corp Exited −1,847,850 −$16.3M —

Showing the 10 largest of 82 changes.

Q1 2026

quarter ended March 31, 2026 · filed May 14, 2026

Company Action Shares changed Value of change % of portfolio
The Cigna Group Exited −172,203 −$47.4M —
Sanofi Sa Trimmed −732,015 −$35.3M 1.7%
Celcuity Inc Trimmed −283,224 −$32.3M 3.2%
Zimmer Biomet Holdings Inc Trimmed −323,029 −$29.2M 0.8%
Rhythm Pharmaceuticals Inc Exited −265,700 −$28.4M —
Corcept Therapeutics Inc New +674,759 +$27.2M 3.9%
Cencora Inc Added +84,994 +$26.7M 4.5%
Kenvue Inc Exited −1,465,442 −$25.3M —
WH Waystar Hldg Corp Added +1,028,511 +$24.8M 5.7%
Gsk PLC New +385,879 +$21.3M 3.1%

Showing the 10 largest of 79 changes.

Q4 2025

quarter ended December 31, 2025 · filed February 17, 2026

Company Action Shares changed Value of change % of portfolio
The Cigna Group New +172,203 +$47.4M 7.5%
Zimmer Biomet Holdings Inc New +385,642 +$34.7M 5.5%
Celcuity Inc Trimmed −309,459 −$30.9M 7.5%
Rhythm Pharmaceuticals Inc New +265,700 +$28.4M 4.5%
Organon & Co New +3,421,765 +$24.5M 3.9%
Icon PLC New +127,202 +$23.2M 3.6%
WH Waystar Hldg Corp New +613,725 +$20.1M 3.2%
Livanova PLC New +322,382 +$19.8M 3.1%
Sanofi Sa Added +408,983 +$19.8M 7.4%
Disc Medicine Inc Trimmed −227,201 −$18M 0.7%

Showing the 10 largest of 61 changes.

Q3 2025

quarter ended September 30, 2025 · filed November 13, 2025

Company Action Shares changed Value of change % of portfolio
Celcuity Inc New +786,526 +$38.9M 9.8%
Alkermes PLC New +674,840 +$20.2M 5.1%
Bright Minds Biosciences Inc Trimmed −321,574 −$19.5M 2.9%
Sanofi Sa Added +375,203 +$17.7M 6.7%
Henry Schein Inc New +219,207 +$14.5M 3.7%
GM Globus Med Inc Exited −245,570 −$14.5M —
Kenvue Inc New +844,000 +$13.7M 3.5%
Dianthus Therapeutics Inc Added +341,680 +$13.4M 5.8%
Neurocrine Biosciences Inc Exited −100,725 −$12.7M —
Gsk PLC New +268,873 +$11.6M 2.9%

Showing the 10 largest of 49 changes.

Q2 2025

quarter ended June 30, 2025 · filed August 13, 2025

Company Action Shares changed Value of change % of portfolio
Icon PLC Exited −203,311 −$35.6M —
Zimmer Biomet Holdings Inc Exited −187,685 −$21.2M —
Labcorp Holdings Inc Exited −83,873 −$19.5M —
Teleflex Incorporated Exited −107,780 −$14.9M —
CD Centene Corp Del New +262,500 +$14.2M 5.4%
Disc Medicine Inc Added +211,276 +$11.2M 5.8%
Neurocrine Biosciences Inc Trimmed −86,848 −$10.9M 4.8%
Embecta Corp Trimmed −1,076,444 −$10.4M 0.1%
IL Idexx Labs Inc New +18,000 +$9.65M 3.7%
S Sanofi New +187,500 +$9.06M 3.5%

Showing the 10 largest of 59 changes.

Q1 2025

quarter ended March 31, 2025 · filed May 15, 2025

Company Action Shares changed Value of change % of portfolio
The Cigna Group Exited −98,003 −$27.1M —
Merck & Co Inc New +270,596 +$24.3M 7.2%
Neurocrine Biosciences Inc New +187,573 +$20.7M 6.2%
S Sanofi Exited −387,000 −$18.7M —
GM Globus Med Inc New +207,000 +$15.2M 4.5%
Biomarin Pharmaceutical Inc New +141,134 +$9.98M 3.0%
Viatris Inc Exited −730,000 −$9.09M —
Organon & Co Exited −606,410 −$9.05M —
Embecta Corp Added +682,039 +$8.7M 4.2%
HM Haemonetics Corp Mass New +133,966 +$8.51M 2.5%

Showing the 10 largest of 47 changes.

Q4 2024

quarter ended December 31, 2024 · filed February 14, 2025

Company Action Shares changed Value of change % of portfolio
Icon PLC New +195,500 +$41M 11.5%
Intuitive Surgical Inc Exited −59,000 −$29M —
Teva Pharmaceutical Industries Ltd Exited −1,349,274 −$24.3M —
The Cigna Group Added +71,500 +$19.7M 7.6%
S Sanofi New +387,000 +$18.7M 5.3%
Maximus Inc Added +226,281 +$16.9M 8.0%
Bright Minds Biosciences Inc New +451,793 +$16.3M 4.6%
Labcorp Holdings Inc Trimmed −60,000 −$13.8M 7.3%
Anteris Technologies Global New +2,370,000 +$13.2M 3.7%
Kenvue Inc Exited −474,741 −$11M —

Showing the 10 largest of 46 changes.

Q3 2024

quarter ended September 30, 2024 · filed November 14, 2024

Company Action Shares changed Value of change % of portfolio
Insmed Inc Exited −1,362,700 −$91.3M —
Intuitive Surgical Inc New +59,000 +$29M 11.5%
Teva Pharmaceutical Industries Ltd New +1,349,274 +$24.3M 9.6%
Teleflex Incorporated Trimmed −71,806 −$17.8M 3.9%
Labcorp Holdings Inc Trimmed −72,609 −$16.2M 15.4%
Maximus Inc New +155,142 +$14.5M 5.7%
Smith & Nephew PLC Exited −579,619 −$14.4M —
Pacira Biosciences Inc Exited −455,500 −$13M —
Organon & Co Exited −608,096 −$12.6M —
Gsk PLC Exited −312,000 −$12M —

Showing the 10 largest of 43 changes.

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