Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.
Reported portfolio value by quarter (5 quarters reported)
$178M in Q4 2016 → $183M now. Hover for any quarter.
As reported for the quarter ended December 31, 2017. Activity is the change in share count since the prior quarter's filing.
| Holding | % of portfolio | Activity | Shares | Value |
|---|---|---|---|---|
| Nucana PLC | 25.8% | Added 600% | 4,666,666 | $47.2M |
| OS Obseva Sa | 25.3% | Added 27% | 4,749,623 | $46.4M |
| Aclaris Therapeutics, Inc. | 20.7% | Unchanged | 1,539,480 | $38M |
| ST Spark Therapeutics, Inc. | 13.5% | Unchanged | 481,270 | $24.7M |
| Natera, Inc. | 7.6% | Unchanged | 1,550,280 | $13.9M |
| AM Auris Medical Holding Ag | 2.5% | Unchanged | 7,818,175 | $4.62M |
| HC Histogenics Corporation | 2.3% | Unchanged | 2,077,040 | $4.26M |
| Synlogic, Inc. | 2.3% | Unchanged | 424,972 | $4.12M |
What changed each quarter, from the filings' own share counts. Largest moves first; most recent 4 quarters.
quarter ended December 31, 2017 · filed February 14, 2018
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| Nucana PLC | Added | +4,000,000 | +$40.4M | 25.8% |
| OS Obseva Sa | Added | +1,000,000 | +$9.76M | 25.3% |
quarter ended September 30, 2017 · filed October 11, 2017
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| V Versartis, Inc. | Exited | −1,563,260 | −$27.3M | — |
| ST Spark Therapeutics, Inc. | Trimmed | −211,858 | −$18.9M | 26.2% |
| Nucana PLC | New | +666,666 | +$12.2M | 7.5% |
| Synlogic, Inc. | New | +424,972 | +$8.08M | 4.9% |
| MT Mirna Therapeutics, Inc. | Exited | −2,974,812 | −$4.97M | — |
| IH Innocoll Holdings PLC | Exited | −2,103,173 | −$4.8M | — |
quarter ended June 30, 2017 · filed July 19, 2017
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| SB Sophiris Bio Inc. | Exited | −200,000 | −$566K | — |
| ST Spark Therapeutics, Inc. | Trimmed | −6,302 | −$376K | 23.2% |
quarter ended March 31, 2017 · filed April 10, 2017
| Company | Action | Shares changed | Value of change | % of portfolio |
|---|---|---|---|---|
| OS Obseva Sa | New | +3,749,623 | +$39M | 20.6% |
| Aclaris Therapeutics, Inc. | Trimmed | −750,000 | −$22.4M | 24.2% |
| V Versartis, Inc. | Trimmed | −798,718 | −$17.1M | 17.6% |
| ST Spark Therapeutics, Inc. | Trimmed | −205,556 | −$11M | 19.7% |
| AM Auris Medical Holding Ag | Added | +2,000,000 | +$1.84M | 3.8% |
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