TRV GP II, LLC

Quarterly 13F snapshot: US-listed longs only, no performance figures — 13F data cannot support them.

Reported portfolio value by quarter (20 quarters reported)

$555M $1.34M

Q4 17 Q4 18 Q4 19 Q4 20 Q4 21 Q3 22

$555M in Q4 2017 → $1.34M now. Hover for any quarter.

Holdings

As reported for the quarter ended September 30, 2022. Activity is the change in share count since the prior quarter's filing.

Holding	% of portfolio	Activity	Shares	Value
JT Jounce Therapeutics, Inc.	100.0%	Trimmed 57%	572,829	$1.34M

What changed each quarter, from the filings' own share counts. Largest moves first; most recent 8 quarters.

quarter ended September 30, 2022 · filed November 03, 2022

Company	Action	Shares changed	Value of change	% of portfolio
JT Jounce Therapeutics, Inc.	Trimmed	−775,000	−$1.81M	100.0%
Allena Pharmaceuticals, Inc.	Exited	−2,790,964	−$533K	—

quarter ended June 30, 2022 · filed August 12, 2022

No position changes this quarter.

quarter ended March 31, 2022 · filed May 10, 2022

Company	Action	Shares changed	Value of change	% of portfolio
JT Jounce Therapeutics, Inc.	Trimmed	−1,350,000	−$9.17M	93.4%

quarter ended December 31, 2021 · filed February 14, 2022

No position changes this quarter.

quarter ended September 30, 2021 · filed November 05, 2021

Company	Action	Shares changed	Value of change	% of portfolio
JT Jounce Therapeutics, Inc.	Trimmed	−1,750,000	−$13M	88.8%

quarter ended June 30, 2021 · filed August 11, 2021

Company	Action	Shares changed	Value of change	% of portfolio
Revolution Medicines, Inc.	Exited	−1,909,317	−$87.6M	—
JT Jounce Therapeutics, Inc.	Trimmed	−2,052,520	−$14M	89.3%

quarter ended March 31, 2021 · filed May 12, 2021

Company	Action	Shares changed	Value of change	% of portfolio
JT Jounce Therapeutics, Inc.	Trimmed	−2,700,000	−$27.7M	42.2%

quarter ended December 31, 2020 · filed February 16, 2021

Company	Action	Shares changed	Value of change	% of portfolio
JT Jounce Therapeutics, Inc.	Trimmed	−1,030,000	−$7.21M	44.9%

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