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FY2015
12 months to Dec 31, 2015
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FY2014
12 months to Dec 31, 2014
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FY2013
12 months to Dec 31, 2013
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FY2012
12 months to Dec 31, 2012
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FY2011
12 months to Dec 31, 2011
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net income (loss) | |||||
| Adjustments for non-cash operating items: | |||||
| Stock-based compensation | |||||
| Impairment of intangible assets | |||||
| Loss on extinguishment of Convertible Notes | |||||
| Amortization of debt discount and debt issuance costs | |||||
| Depreciation on property and equipment | |||||
| Asset impairment and other charges | |||||
| Accretion of discount on securities | |||||
| Excess tax benefits from stock-based compensation | |||||
| Changes in deferred income taxes | |||||
| Change in fair value of contingent purchase consideration | |||||
| Amortization of deferred revenue | |||||
| Release of valuation allowance for deferred income taxes | |||||
| Other non-cash items | |||||
| Changes in operating assets and liabilities: | |||||
| Receivable from collaboration partners | |||||
| Prepaid expenses and other current assets | |||||
| Other non-current assets | |||||
| Accounts payable, accrued expenses and other current liabilities | |||||
| Current taxes payable | |||||
| Other non-current liabilities | |||||
| Net cash provided by (used) in operating activities | |||||
| Cash flows from investing activities: | |||||
| Payments under Agreement | |||||
| BioMarin Pharmaceutical Inc. | |||||
| CureTech Ltd | |||||
| Total payments under Agreement | |||||
| Purchases of short-term investments | |||||
| Sales or maturities of short-term investments | |||||
| Purchases of property and equipment | |||||
| Change in restricted cash | |||||
| Net cash (used in) provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Principal repayment of Convertible Notes | |||||
| Cash settlement of Convertible Notes conversion premium | |||||
| Proceeds from borrowings under Revolving Credit Facility | |||||
| Principal repayment of borrowings under Revolving Credit Facility | |||||
| Financing transaction costs | |||||
| Excess tax benefits from stock-based compensation | |||||
| Proceeds from issuance of common stock under equity incentive and stock purchase plans | |||||
| Reduction of build-to-suit lease obligation | |||||
| Purchases of short-term investments | |||||
| Maturities of short-term investments | |||||
| Net cash (used in) provided by financing activities | |||||
| Net (decrease) increase in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of year | |||||
| Cash and cash equivalents at end of year | |||||
| Supplemental disclosures of cash flow information: | |||||
| Interest | |||||
| Income taxes, net of refunds | |||||
| Non-cash investing and financing activities: | |||||
| Reacquisition of Convertible Notes equity component upon conversion | |||||
| Fair value of common stock issued for conversion of Convertible Notes | |||||
| Derecognition of build-to-suit lease asset | |||||
| Derecognition of build-to-suit lease obligations | |||||
| Property and equipment expenditures incurred but not yet paid | |||||
| Interest capitalized during construction period for build-to-suit lease transactions | |||||
| Accrued interest payable forfeited upon conversion of Convertible Notes | |||||
| Amounts capitalized under build-to-suit lease transactions | |||||
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