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FY2012
12 months to Dec 31, 2012
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FY2011
12 months to Dec 31, 2011
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FY2010
12 months to Dec 31, 2010
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|---|---|---|---|
| Cash flows from operating activities: | |||
| Net income (loss) | |||
| Adjustments to reconcile net income (loss) to net cash used in operating activities: | |||
| Deferred income taxes | |||
| Depreciation | |||
| Stock-based compensation | |||
| Amortization of convertible senior notes discount and debt issuance costs | |||
| Amortization of finite-lived intangible assets | |||
| Changes in fair value of liability for contingent consideration | |||
| Property and equipment write-off | |||
| Impairment of equity investment | |||
| Accretion of lease exit costs liability | |||
| Realized gains on sales of current marketable securities | |||
| Non-cash tax benefit | |||
| Changes in operating assets and liabilities: | |||
| Restricted cash | |||
| Accounts receivable | |||
| Receivable from collaboration partners | |||
| Inventory | |||
| Prepaid expenses and other current assets | |||
| Other assets | |||
| Accounts payable | |||
| Accrued liabilities | |||
| Accrued clinical trials and related expenses | |||
| Accrued compensation | |||
| Deferred revenue | |||
| Escrow liability | |||
| Lease termination exit costs liability | |||
| Other current liabilities | |||
| Other liabilities | |||
| Acquisition of Proteolix, Inc. net of cash acquired | |||
| Net cash (used in) provided by operating activities | |||
| Cash flows from investing activities: | |||
| Purchases of marketable securities | |||
| Sales of marketable securities | |||
| Maturities of marketable securities | |||
| Transfers from restricted cash | |||
| Payment for liability for contingent consideration, current | |||
| Capital expenditures | |||
| Repayment of notes payable | |||
| Repurchases of restricted stock awards | |||
| Net cash (used in) provided by investing activities | |||
| Cash flows from financing activities: | |||
| Repurchases of restricted stock awards | |||
| Payment to collaboration partner | |||
| Net proceeds from issuances of common stock | |||
| Proceeds from issuance of convertible senior notes | |||
| Convertible senior notes debt issuance costs | |||
| Excess tax benefit from stock-based awards | |||
| Net increase (decrease) in cash and cash equivalents | |||
| Net cash provided by financing activities | |||
| Net increase (decrease) in cash and cash equivalents | |||
| Cash and cash equivalents at beginning of period | |||
| Cash and cash equivalents at end of period | |||
| Supplemental cash flow data | |||
| Cash paid during the period for income taxes | |||
| Cash paid during the period for interest | |||
| Equity issued in lieu of cash payment of contingent consideration liability |
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