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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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FY2019
12 months to Dec 31, 2019
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FY2018
12 months to Dec 31, 2018
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|---|---|---|---|---|
| Operating activities | ||||
| Net loss | ||||
| Adjustments to reconcile net loss to net cash used in operating activities: | ||||
| Depreciation and amortization | ||||
| Stock-based compensation | ||||
| Loss from remeasurement of development derivative liability | ||||
| Non-cash interest expense | ||||
| Change in fair value warrant liability | ||||
| Change in fair value derivative liability | ||||
| Non-cash research and development expense | ||||
| Other non-cash transactions | ||||
| Changes in operating assets and liabilities: | ||||
| Other receivables | ||||
| Prepaid expenses and other assets | ||||
| Accounts payable | ||||
| Accrued expenses and other current liabilities | ||||
| Deferred sublicense revenue | ||||
| Net cash used in operating activities | ||||
| Investing activities | ||||
| Purchases of property and equipment | ||||
| Acquisition of intellectual property rights | ||||
| Net cash used in investing activities | ||||
| Financing activities | ||||
| Proceeds from development derivative liability | ||||
| Proceeds from issuance of common stock in public offering, net | ||||
| Payments of deferred stock offering costs | ||||
| Proceeds from issuance of redeemable convertible preferred stock, net | ||||
| Long-term borrowings, net | ||||
| Proceeds from exercise of stock options | ||||
| Proceeds from exercise of warrants | ||||
| Shares purchased through employee stock purchase plan | ||||
| Repayments of long-term debt | ||||
| Net cash provided by financing activities | ||||
| Net increase (decrease) in cash and cash equivalents | ||||
| Cash and cash equivalents at the beginning of the year | ||||
| Cash and cash equivalents at the end of the year | ||||
| Supplemental disclosure for cash flow | ||||
| Cash paid for interest | ||||
| Supplemental disclosure of cash flow information | ||||
| Accrued interest on term loan refinanced to principal | ||||
| Debt refinanced through new term loan | ||||
| Right-of-use asset and lease liabilities recorded upon adoption of ASC 842 | ||||
| Conversion of redeemable convertible preferred stock into common stock | ||||
| Conversion of convertible promissory notes into redeemable convertible preferred stock | ||||
| Warrant liability converted to redeemable convertible preferred stock upon the exercise of warrants | ||||
| Right-of-use assets obtained in exchange for new operating lease liabilities | ||||
| Issuance of warrants in conjunction with development derivative liability | ||||
| Purchases of property and equipment in conjunction with development derivative liability | ||||
| Issuance of warrants in conjunction with debt | ||||
| Conversion of redeemable convertible preferred stock warrants into common stock warrants | ||||
| Accretion of redeemable convertible preferred stock | ||||
| Deferred stock offering costs in accounts payable | ||||
| Purchases of property and equipment included in accounts payable and accrued expenses | ||||
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