Company Executives

Management Team

From Forms 3, 4 and 5 filed in the last 18 months

Officer	Age	In this role	Joined	2024 pay
Bradley L. Campbell Also a director President and CEO Title from the Form 4 dated Apr 27, 2026	49	Not stated	Not stated	$8,526,943
Simon N.R. Harford Chief Financial Officer Title from the Form 4 dated Apr 27, 2026	Not stated	Not stated	Not stated	$3,449,065
Ellen Rosenberg Chief Legal Officer Title from the Form 4 dated Apr 27, 2026	Not stated	Not stated	Not stated	$3,800,307
Samantha Prout Chief Accounting Officer Title from the Form 4 dated Apr 27, 2026	Not stated	Not stated	Not stated	Not reported
Jeff Castelli Chief Development Officer Title from the Form 4 dated Apr 27, 2026	Not stated	Not stated	Not stated	$3,442,896
David Michael Clark Chief People Officer Title from the Form 4 dated Apr 27, 2026	Not stated	Not stated	Not stated	$3,015,209

Each officer opens the passage of the filing that names them. A title that changed since the list comes from the officer's latest Form 3, 4 or 5, and its start year is not stated there. "Not stated" means the filing does not say. Pay is the proxy's Summary Compensation Table, which reports only the named executive officers.

Board of Directors

From the proxy statement filed Apr 24, 2025

Directors

serving now

Independent

8 of 8

stated in the proxy; 1 not stated

Average tenure

10.4 years

from year joined

CEO also chairs the board

Michael G. Raab

Director	Age	On board	Independent	Committees	Other public boards	2024 pay
Michael A. Kelly	68	2020 5 years	Independent	Science and Technology	Prime Medicine, Inc.	$433,665
Margaret G. McGlynn	65	2009 16 years	Independent	Compensation and Leadership Development · Chair Nominating and Corporate Governance	Novavax, Inc.	$442,500
Michael G. Raab Board chair	60	2004 21 years	Independent	Nominating and Corporate Governance	Ardelyx, Inc., Tempest Therapeutics, Inc.	$492,527
Glenn P. Sblendorio	69	2006 19 years	Independent	Audit and Compliance · Chair Compensation and Leadership Development	Mineralys Therapeutics	$455,000
Lynn D. Bleil	61	2018 7 years	Independent	Nominating and Corporate Governance · Chair Compensation and Leadership Development	Sonova Holding AG, Alcon AG	$438,125
Bradley L. Campbell CEO	49	2018 7 years	Not stated	None stated	None stated	Paid as CEO
Eiry W. Roberts, M.D.	61	2021 4 years	Independent	Compensation and Leadership Development Science and Technology	None stated	$432,500
Craig A. Wheeler	64	2016 9 years	Independent	Audit and Compliance Science and Technology · Chair	Apellis Pharmaceuticals, Inc.	$442,165
Burke W. Whitman	69	2019 6 years	Independent	Audit and Compliance Nominating and Corporate Governance	Omega Healthcare Investors	$433,665

Each director opens the passage of the proxy that names them. "Not stated" means the proxy does not say; it never means "no". Pay is the proxy's Director Compensation table; the CEO is paid as an executive.

1 disclosed in the proxy filed Apr 24, 2025

Mr. Crowley

President and CEO of BIO, a biotech trade association

$200,645

last fiscal year

Company paid membership dues to BIO, a biotech trade association of which Mr. Crowley is President and CEO.

With Biotechnology Innovation Organization (BIO) Open in proxy

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Company Executives

Management Team

Board of Directors

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