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FY2017
12 months to Dec 31, 2017
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FY2016
12 months to Dec 31, 2016
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FY2015
12 months to Dec 31, 2015
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FY2014
12 months to Dec 31, 2014
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FY2013
12 months to Dec 31, 2013
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation | |||||
| Stock-based compensation expense | |||||
| Change in fair value of warrant liability | |||||
| Fair value of warrant liability in excess of proceeds from financing | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Prepaid expenses and other current assets | |||||
| Accounts payable | |||||
| Accrued clinical expenses | |||||
| Accrued payroll | |||||
| Other accrued liabilities | |||||
| Deferred revenue | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Property and equipment purchases | |||||
| Net cash provided by (used in) investing activities | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Net proceeds from issuance of preferred stock, warrants and options | |||||
| Proceeds from issuance of common stock, net of offering costs | |||||
| Net proceeds from issuance of common stock pursuant to an equity purchase agreement | |||||
| Net proceeds from issuance of common stock pursuant to an at-market issuance sales agreement | |||||
| Net proceeds from issuance of common stock and warrants pursuant to equity offerings | |||||
| Net proceeds from issuance of common stock pursuant to equity offerings | |||||
| Net proceeds from issuance of common stock to collaborative partner | |||||
| Net proceeds from issuance of common stock pursuant to exercise of warrants | |||||
| Net proceeds from issuance of common stock pursuant to exercise of stock options and employee stock purchase plan | |||||
| Net cash provided by (used in) financing activities | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash and cash equivalents | |||||
| Cash and cash equivalents, beginning of period | |||||
| Cash and cash equivalents, end of period | |||||
| SUPPLEMENTAL CASH FLOW INFORMATION | |||||
| Issuance of common stock as a commitment fee pursuant to an equity purchase agreement | |||||
| Issuance of common stock to settle a license fee obligation | |||||
| Fair value of warrants issued in connection with registered direct offering | |||||
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