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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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FY2019
12 months to Dec 31, 2019
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FY2018
12 months to Dec 31, 2018
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FY2017
12 months to Dec 31, 2017
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Stock-based compensation | |||||
| Depreciation and amortization | |||||
| Deferred income taxes | |||||
| Noncash lease expense | |||||
| Amortization of debt discount and issuance costs | |||||
| Net accretion and amortization of investments in marketable securities | |||||
| Realized gain on sale of marketable securities | |||||
| Change in fair value of common stock warrant liabilities | |||||
| Acquired in-process research and development (IPR&D) | |||||
| Change in fair value of contingent consideration | |||||
| Inventory write-down | |||||
| Asset impairment charges | |||||
| Loss on extinguishment of debt | |||||
| Other | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Inventory | |||||
| Prepaid expenses and other current assets | |||||
| Other assets | |||||
| Accounts payable, accrued and other current liabilities | |||||
| Contingent consideration liability | |||||
| Operating lease liability | |||||
| Deferred revenue | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Cash paid for IPR&D assets | |||||
| Purchase of Tevard note receivable | |||||
| Purchases of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Proceeds from sale of marketable securities | |||||
| Purchases of property and equipment | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows from financing activities: | |||||
| Payments for contingent consideration liability | |||||
| Principal repayments of long-term debt | |||||
| Payment of fees to extinguish long-term debt | |||||
| Proceeds from issuance of common stock under equity incentive plans | |||||
| Payments of tax withholding obligation on vesting restricted stock units | |||||
| Net proceeds from issuance of convertible debt | |||||
| Payment of debt issuance costs | |||||
| Proceeds from issuance of common stock, net | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of period | |||||
| Cash and cash equivalents at end of period | |||||
| Supplemental Cash Flow Information | |||||
| Cash paid for interest | |||||
| Noncash investing and financing activities: | |||||
| Common stock issued as consideration for asset acquisition | |||||
| Net liabilities assumed in connection with asset acquisition | |||||
| Purchases of property and equipment in accounts payable | |||||
| Extinguishment of note payable advanced by a customer under a contract manufacturing supply agreement through net settlement of our receivables from the customer | |||||
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