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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
|
FY2023
12 months to Dec 31, 2023
|
FY2022
12 months to Dec 31, 2022
|
FY2021
12 months to Dec 31, 2021
|
|
|---|---|---|---|---|---|
| Operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Non-cash loss on extinguishment of debt and exchange transaction | |||||
| Non-cash royalty revenue | |||||
| Paid-in-kind interest on long-term debt | |||||
| Non-cash interest expense related to the revenue interest liability | |||||
| Non-cash interest expense related to the royalty sale liability | |||||
| Stock-based compensation expense | |||||
| Depreciation expense | |||||
| Accretion and amortization of premiums and discounts on investments | |||||
| Amortization of debt issuance costs and discounts | |||||
| Changes in assets and liabilities: | |||||
| Accounts receivable | |||||
| Prepaids and other assets | |||||
| Deferred revenue | |||||
| Inventories | |||||
| Accounts payable | |||||
| Other accrued liabilities | |||||
| Other long-term liabilities | |||||
| Net cash used in operating activities | |||||
| Investing activities | |||||
| Purchases of investments | |||||
| Proceeds from sales/maturities of investments | |||||
| Purchases of property and equipment | |||||
| Net cash (used in) provided by investing activities | |||||
| Financing activities | |||||
| Proceeds from royalty sale liability | |||||
| Payment of royalty sale liability issuance costs | |||||
| Repurchase or principal payment of revenue interest liability | |||||
| Payments on revenue interest liability | |||||
| Payment for other issuance costs | |||||
| Proceeds from credit agreement, net of issuance costs | |||||
| Proceeds from issuance of convertible notes, net of issuance costs | |||||
| Repayment of convertible notes | |||||
| Proceeds from issuance of common stock, net of issuance costs | |||||
| Proceeds from issuance of common stock from ATM Program, net of issuance costs | |||||
| Proceeds from exercise of warrants | |||||
| Proceeds from exercise of pre-funded warrants | |||||
| Other financing activities | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash and cash equivalents | |||||
| Cash, cash equivalents at beginning of period | |||||
| Cash and cash equivalents at end of period | |||||
| Supplemental disclosure of cash flow information: | |||||
| Issuance costs not yet paid | |||||
| Purchase of property and equipment not yet paid | |||||
| Non-cash right of use asset | |||||
| Income taxes paid (refer to Note 17) | |||||
| Cash paid for interest | |||||
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