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FY2017
12 months to Dec 31, 2017
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FY2016
12 months to Dec 31, 2016
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FY2015
12 months to Dec 31, 2015
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FY2014
12 months to Dec 31, 2014
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FY2013
1 months to Feb 28, 2014
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|---|---|---|---|---|---|
| Net loss | |||||
| Operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation expense | |||||
| Acquired in-process research and development | |||||
| Depreciation and amortization expense | |||||
| Stock-based compensation expense | |||||
| Non-cash interest expense | |||||
| Write-down of inventory to net realizable value | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Inventories | |||||
| Other assets | |||||
| Accounts payable | |||||
| Accrued expenses | |||||
| Deferred revenues | |||||
| Other liabilities | |||||
| Net cash used in operating activities | |||||
| Investing Activities | |||||
| Acquisition of product candidates, technology licenses and milestone payments | |||||
| Purchase of property and equipment | |||||
| Change in restricted cash | |||||
| Net cash used in investing activities, Total | |||||
| Net Cash Provided by (Used in) Financing Activities | |||||
| Proceeds from sales of common stock, net of issuance costs | |||||
| Proceeds from exercise of stock options | |||||
| Proceeds from issuance of common stock under Employee Stock Purchase Plan | |||||
| Payment of minimum tax withholdings on share-based awards | |||||
| Increase in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of period | |||||
| Cash and cash equivalents at end of period | |||||
| Proceeds from term loan, net of issuance costs | |||||
| Proceeds from exercise of stock options and Employee Stock Purchase Plan | |||||
| Net cash provided by financing activities | |||||
| Effect of exchange rate changes on cash and cash equivalents | |||||
| Increase (decrease) in cash and cash equivalents | |||||
| Cash and cash equivalents at beginning of period | |||||
| Cash and cash equivalents at end of period | |||||
| Non-cash investing and financing activities | |||||
| Stock option exercise proceeds receivable as of period end | |||||
| Noncash or Part Noncash Acquisition, Fixed Assets Acquired | |||||
| Leasehold improvement assets funded by lessor | |||||
| Purchase of property and equipment - cash not paid as of period end | |||||
| Supplemental cash flow information | |||||
| Cash paid for interest | |||||
| Income Taxes Paid | |||||
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