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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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|---|---|---|---|---|---|
| Operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Non-cash interest expense on liability related to the sales of future royalties, net of issuance costs accretion | |||||
| Depreciation | |||||
| Share-based compensation expense | |||||
| Change in fair value of warrant liabilities | |||||
| Issuance costs allocated to warrant liabilities | |||||
| Amortization and accretion of available-for-sale investments, net | |||||
| Gain on termination of operating lease | |||||
| Loss on disposal of fixed assets | |||||
| Gain on extinguishment of debt | |||||
| Non-cash interest expense | |||||
| Accretion of debt discount | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable, prepaid expenses and other current assets | |||||
| Other assets and liabilities | |||||
| Accounts payable and accrued liabilities (includes $248 and $82 to a related party for the year ended December 31, 2024 and 2023, respectively) | |||||
| Deferred revenue | |||||
| Net cash used in operating activities | |||||
| Investing activities | |||||
| Purchase of short-term investments | |||||
| Maturity of short-term investments | |||||
| Acquisition of property and equipment | |||||
| Net cash used in investing activities | |||||
| Financing activities | |||||
| Proceeds from issuance of common stock and warrants in registered direct offering, net of issuance costs | |||||
| Proceeds from royalty purchase and sale agreement, net of $1,862 of issuance costs | |||||
| Payments on royalty purchase and sale agreement | |||||
| Proceeds from at-the-market sales agreement, net of issuance costs | |||||
| Proceeds from registered direct offering, net of issuance costs | |||||
| Proceeds from shares issued under employee stock purchase plan | |||||
| Proceeds from exercise of stock options | |||||
| Proceeds from issuance of long-term debt | |||||
| Principal payments made on long-term debt | |||||
| Net cash provided by financing activities | |||||
| Net (decrease) increase in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of period | |||||
| Cash, cash equivalents and restricted cash, end of period | |||||
| Supplemental disclosure | |||||
| Interest paid | |||||
| Purchase of property and equipment in accounts payable and accrued liabilities | |||||
| Forgiveness of PPP Loan and accrued interest | |||||
| Reconciliation of cash, cash equivalents and restricted cash: | |||||
| Cash and cash equivalents | |||||
| Restricted cash (recorded in other current assets) | |||||
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