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$72.02 -$0.80 (1.1%)

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Insider Transactions

Insider Transaction Summary

INVESTMENTS, LP RTW

4,795,000 shares

Net: 0 B/S: -

Asset Management, LP Cormorant

2,514,545 shares

Net: 0 B/S: -

LILLY & Co ELI

2,169,396 shares

Net: 0 B/S: -

Venture Investments, LLC Alexandria

502,365 shares

Net: 0 B/S: -

Sarah Boyce

305,871 shares

Net: 0 B/S: 1.0

Teresa McCarthy

97,130 shares

Net: 0 B/S: 1.0

Joseph Baroldi

87,000 shares

Net: 0 B/S: -

Jae B. Kim

82,000 shares

Net: 0 B/S: -

W. Michael Flanagan

80,195 shares

Net: 0 B/S: 1.0

TROY EDWARD WILSON

69,425 shares

Net: +6,692 B/S: 1.18

Michael F MacLean

65,806 shares

Net: -30,914 B/S: -

Eric Mosbrooker

55,000 shares

Net: 0 B/S: 1.0

Kathleen P. Gallagher

50,204 shares

Net: -1,099 B/S: -

John B Moriarty

47,755 shares

Net: -2,245 B/S: -

Charles III Calderaro

40,000 shares

Net: 0 B/S: -

Steven George Hughes

38,867 shares

Net: 0 B/S: 1.0

ARTHUR A LEVIN

19,650 shares

Net: +6,692 B/S: 1.06

RODERICK WONG

15,000 shares

Net: 0 B/S: -

Jean Jinsun Kim

6,692 shares

Net: +6,692 B/S: ∞

Simona Skerjanec

6,692 shares

Net: +6,692 B/S: ∞

Tamar Thompson

6,692 shares

Net: +6,692 B/S: ∞

CARSTEN BOESS

6,692 shares

Net: +6,692 B/S: ∞

Edward M. MD Kaye

6,692 shares

Net: +6,692 B/S: ∞

Noreen Henig

6,692 shares

Net: +6,692 B/S: ∞

Insider Name	Current Shares	Net Change (1yr)	Buy/Sell Ratio
INVESTMENTS, LP RTW	4,795,000	0	-
Asset Management, LP Cormorant	2,514,545	0	-
LILLY & Co ELI	2,169,396	0	-
Venture Investments, LLC Alexandria	502,365	0	-
Sarah Boyce	305,871	0	1.0
Teresa McCarthy	97,130	0	1.0
Joseph Baroldi	87,000	0	-
Jae B. Kim	82,000	0	-
W. Michael Flanagan	80,195	0	1.0
TROY EDWARD WILSON	69,425	+6,692	1.18
Michael F MacLean	65,806	-30,914	-
Eric Mosbrooker	55,000	0	1.0
Kathleen P. Gallagher	50,204	-1,099	-
John B Moriarty	47,755	-2,245	-
Charles III Calderaro	40,000	0	-
Steven George Hughes	38,867	0	1.0
ARTHUR A LEVIN	19,650	+6,692	1.06
RODERICK WONG	15,000	0	-
Jean Jinsun Kim	6,692	+6,692	∞
Simona Skerjanec	6,692	+6,692	∞
Tamar Thompson	6,692	+6,692	∞
CARSTEN BOESS	6,692	+6,692	∞
Edward M. MD Kaye	6,692	+6,692	∞
Noreen Henig	6,692	+6,692	∞

Individual Transactions

October 03, 2025

Eric Mosbrooker

Open Market Sale

Change: -6,562

Price: $45.38

Shares: 55,000

Value: -$297,771

Eric Mosbrooker

Option Exercise/Conversion

Change: +6,562

Price: $9.05

Shares: 61,562

Value: +$59,386

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric Mosbrooker	Oct 07	Open Market Sale (S) Market Sale	55,000	-6,562	$45.38	-$297,771
Eric Mosbrooker	Oct 07	Option Exercise/Conversion (M) Compensation/Award	61,562	+6,562	$9.05	+$59,386

September 22, 2025

Steven George Hughes

Open Market Sale

Change: -2,208

Price: $40.58

Shares: 38,867

Value: -$89,600

Steven George Hughes

Option Exercise/Conversion

Change: +2,208

Price: $10.16

Shares: 41,075

Value: +$22,433

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Steven George Hughes	Sep 23	Open Market Sale (S) Market Sale	38,867	-2,208	$40.58	-$89,600
Steven George Hughes	Sep 23	Option Exercise/Conversion (M) Compensation/Award	41,075	+2,208	$10.16	+$22,433

September 15, 2025

Teresa McCarthy

Open Market Sale

Change: -15,000

Price: $41.41

Shares: 97,130

Value: -$621,142

Teresa McCarthy

Option Exercise/Conversion

Change: +15,000

Price: $22.34

Shares: 112,130

Value: +$335,100

Steven George Hughes

Open Market Sale

Change: -1,542

Price: $45.41

Shares: 38,867

Value: -$70,022

Steven George Hughes

Option Exercise/Conversion

Change: +1,542

Price: $6.57

Shares: 40,409

Value: +$10,130

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Teresa McCarthy	Sep 17	Open Market Sale (S) Market Sale	97,130	-15,000	$41.41	-$621,142
Teresa McCarthy	Sep 17	Option Exercise/Conversion (M) Compensation/Award	112,130	+15,000	$22.34	+$335,100
Steven George Hughes	Sep 17	Open Market Sale (S) Market Sale	38,867	-1,542	$45.41	-$70,022
Steven George Hughes	Sep 17	Option Exercise/Conversion (M) Compensation/Award	40,409	+1,542	$6.57	+$10,130

September 11, 2025

W. Michael Flanagan

Open Market Sale

Change: -20,000

Price: $38.94

Shares: 80,195

Value: -$778,702

W. Michael Flanagan

Option Exercise/Conversion

Change: +20,000

Price: $14.22

Shares: 100,195

Value: +$284,400

Insider	Filing Date	Transaction	Shares	Change	Price	Value
W. Michael Flanagan	Sep 12	Open Market Sale (S) Market Sale	80,195	-20,000	$38.94	-$778,702
W. Michael Flanagan	Sep 12	Option Exercise/Conversion (M) Compensation/Award	100,195	+20,000	$14.22	+$284,400

September 05, 2025

TROY EDWARD WILSON

Open Market Sale

Change: -14,500

Price: $50.00

Shares: 69,425

Value: -$725,000

TROY EDWARD WILSON

Option Exercise/Conversion

Change: +14,500

Price: $12.48

Shares: 83,925

Value: +$180,960

Sarah Boyce

Open Market Sale

Change: -50,000

Price: $49.95

Shares: 305,871

Value: -$2,497,435

Sarah Boyce

Option Exercise/Conversion

Change: +50,000

Price: $1.24

Shares: 355,871

Value: +$62,000

Insider	Filing Date	Transaction	Shares	Change	Price	Value
TROY EDWARD WILSON	Sep 09	Open Market Sale (S) Market Sale	69,425	-14,500	$50.00	-$725,000
TROY EDWARD WILSON	Sep 09	Option Exercise/Conversion (M) Compensation/Award	83,925	+14,500	$12.48	+$180,960
Sarah Boyce	Sep 05	Open Market Sale (S) Market Sale	305,871	-50,000	$49.95	-$2,497,435
Sarah Boyce	Sep 05	Option Exercise/Conversion (M) Compensation/Award	355,871	+50,000	$1.24	+$62,000

September 03, 2025

Eric Mosbrooker

Open Market Sale

Change: -6,563

Price: $47.07

Shares: 55,000

Value: -$308,935

Eric Mosbrooker

Option Exercise/Conversion

Change: +6,563

Price: $9.05

Shares: 61,563

Value: +$59,395

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric Mosbrooker	Sep 05	Open Market Sale (S) Market Sale	55,000	-6,563	$47.07	-$308,935
Eric Mosbrooker	Sep 05	Option Exercise/Conversion (M) Compensation/Award	61,563	+6,563	$9.05	+$59,395

September 02, 2025

Kathleen P. Gallagher

Open Market Sale

Change: -188

Price: $47.42

Shares: 50,204

Value: -$8,914

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Kathleen P. Gallagher	Sep 02	Open Market Sale (S) Market Sale	50,204	-188	$47.42	-$8,914

August 28, 2025

Sarah Boyce

Open Market Sale

Change: -25,000

Price: $49.39

Shares: 305,871

Value: -$1,234,700

Sarah Boyce

Option Exercise/Conversion

Change: +25,000

Price: $1.24

Shares: 330,871

Value: +$31,000

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Sarah Boyce	Aug 29	Open Market Sale (S) Market Sale	305,871	-25,000	$49.39	-$1,234,700
Sarah Boyce	Aug 29	Option Exercise/Conversion (M) Compensation/Award	330,871	+25,000	$1.24	+$31,000

August 22, 2025

Steven George Hughes

Open Market Sale

Change: -2,208

Price: $46.40

Shares: 38,867

Value: -$102,461

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Steven George Hughes	Aug 22	Open Market Sale (S) Market Sale	38,867	-2,208	$46.40	-$102,461