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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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FY2019
12 months to Dec 31, 2019
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FY2018
12 months to Dec 31, 2018
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|---|---|---|---|---|---|
| Operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Stock-based compensation expense | |||||
| Depreciation expense | |||||
| Net amortization of premiums and discounts on investments | |||||
| Gain on sale of property and equipment | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Other non-current assets | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Deferred revenue—related party | |||||
| Other liabilities | |||||
| Net cash used in operating activities | |||||
| Investing activities: | |||||
| Purchases of investments | |||||
| Proceeds from maturities of investments | |||||
| Purchases of property and equipment | |||||
| Net cash provided by (used in) by investing activities | |||||
| Financing activities: | |||||
| Proceeds from at the market offering, net of issuance costs | |||||
| Gilead Stock Purchase Agreement | |||||
| Total proceeds from at the market offering, net of issuance costs | |||||
| Proceeds from exercise of stock options | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of period | |||||
| Cash, cash equivalents and restricted cash, end of period | |||||
| Non-cash investing and financing activities: | |||||
| Purchases of property and equipment in accounts payable and accrued expenses | |||||
| Stock option exercise receivables in prepaid expenses and other current assets | |||||
| Issuance costs in accounts payable and accrued expenses | |||||
| Discount on common stock issued under a stock purchase agreement | |||||
| Supplemental cash flow information: | |||||
| Cash paid for lease liabilities | |||||
| Cash paid for income taxes | |||||
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