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Poseida Therapeutics, Inc.

poseida.com

No Longer Reporting

The company has not filed an annual or quarterly report since its Q3 FY2024 10-Q, filed Nov 7, 2024. Its latest SEC filing is a SCHEDULE 13G/A from May 15, 2025.

The sections below describe the company as of the FY2023 annual report.

What Did They Do?

Develops allogeneic CAR-T therapies for patients with cancer and gene therapies for patients with rare diseases.

How Did They Make Money?

Poseida earns money mainly from collaboration and license agreements: partners pay upfront for intellectual-property licenses, fund research services billed as work is performed, and may owe milestone payments and royalties tied to product sales.

FY2023 revenue

Who Were Their Customers?

Pharmaceutical partners license programs and work with Poseida through collaboration agreements; Poseida also provides research and development services under those agreements.

Did Revenues Turn Into Profits?

No. It lost $123.4M in FY2023.

Operating income, FY2023
−200% of revenue
▲ +116% (Loss) vs FY2022 (−$59.9M, −46%)
Net income, FY2023
−191% of revenue
▲ +93% (Loss) vs FY2022 (−$64M, −49%)
Free cash flow, FY2023
−147% of revenue
▲ +210% (Loss) vs FY2022 (−$30.7M, −24%)

How Were They Changing?

Since the FY2023 annual report
Latest quarter: Q3 FY2024, the three months to Sep 30, 2024
Revenue
▲ +667%
vs $9.4M in Q3 FY2023
Net income
▲ Now profitable
vs −$31.8M in Q3 FY2023
  • Jan 8, 2025 Roche completed its acquisition of Poseida The merger made Poseida a wholly owned subsidiary of Roche.
  • Nov 26, 2024 Roche agreed to acquire Poseida The offer included $9.00 per share in cash and a contingent value right for up to $4.00 per share.
  • May 1, 2024 Poseida signed a cell-therapy collaboration with Astellas Xyphos will develop and commercialize products from two solid-tumor programs generated by the collaboration.

Cell therapy portfolio The earlier report describes both autologous and allogeneic CAR-T candidates; the latest describes an allogeneic portfolio and says enrollment in an autologous prostate cancer program stopped.

Partnered hematology programs The earlier report describes its product-candidate portfolio as wholly owned; the latest says Roche has licensed hematological CAR-T programs and will take over future development after the initial clinical trials.

Who Did They Compete With?

Competes with Adaptimmune Therapeutics, Allogene, Arcellx, Astellas Pharma, Autolus, Bristol-Meyers Squibb, Caribou Biosciences, Cellectis, Janssen Pharmaceuticals, Juno Therapeutics, Gracell Biotechnologies, Kite Pharma, Legend Biotech, Novartis, Takeda, Amgen, AstraZeneca, F. Hoffman-La Roche, GlaxoSmithKline, and Merck &

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