2024 Q1 Form 10-K Financial Statement
#000095017024018395 Filed on February 22, 2024
Income Statement
Concept | 2024 Q1 | 2023 Q4 | 2023 |
---|
Balance Sheet
Concept | 2024 Q1 | 2023 Q4 | 2023 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $1.261B | $1.263B | |
YoY Change | 12.16% | 12.35% | |
Cash & Equivalents | $185.8M | $185.8M | |
Short-Term Investments | $1.075B | $1.077B | |
Other Short-Term Assets | $12.51M | $52.50M | |
YoY Change | 433.8% | 71.19% | |
Inventory | |||
Prepaid Expenses | $39.99M | ||
Receivables | $0.00 | $0.00 | |
Other Receivables | $0.00 | $0.00 | |
Total Short-Term Assets | $1.315B | $1.315B | |
YoY Change | 13.9% | 13.9% | |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $5.424M | $20.51M | |
YoY Change | 69.45% | 160.5% | |
Goodwill | |||
YoY Change | |||
Intangibles | |||
YoY Change | |||
Long-Term Investments | |||
YoY Change | |||
Other Assets | $382.0K | $382.0K | |
YoY Change | -4.5% | -44.64% | |
Total Long-Term Assets | $20.90M | $20.90M | |
YoY Change | 143.97% | 143.97% | |
TOTAL ASSETS | |||
Total Short-Term Assets | $1.315B | $1.315B | |
Total Long-Term Assets | $20.90M | $20.90M | |
Total Assets | $1.336B | $1.336B | |
YoY Change | 14.86% | 14.86% | |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $6.783M | $6.783M | |
YoY Change | 185.12% | 185.12% | |
Accrued Expenses | $41.61M | $44.45M | |
YoY Change | 42.08% | 40.82% | |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | |
YoY Change | |||
Long-Term Debt Due | |||
YoY Change | |||
Total Short-Term Liabilities | $68.13M | $68.13M | |
YoY Change | 100.7% | 100.7% | |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | |
YoY Change | |||
Other Long-Term Liabilities | $0.00 | $13.85M | |
YoY Change | -100.0% | 339.52% | |
Total Long-Term Liabilities | $0.00 | $13.85M | |
YoY Change | -100.0% | 339.52% | |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $68.13M | $68.13M | |
Total Long-Term Liabilities | $0.00 | $13.85M | |
Total Liabilities | $81.97M | $81.97M | |
YoY Change | 120.98% | 120.98% | |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$997.9M | ||
YoY Change | 76.87% | ||
Common Stock | $2.256B | ||
YoY Change | 33.22% | ||
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | $4.524M | ||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $1.254B | $1.254B | |
YoY Change | |||
Total Liabilities & Shareholders Equity | $1.336B | $1.336B | |
YoY Change | 14.86% | 14.86% |
Cashflow Statement
Concept | 2024 Q1 | 2023 Q4 | 2023 |
---|
Facts In Submission
Frame | Concept Type | Concept / XBRL Key | Value | Unit |
---|---|---|---|---|
CY2023 | dei |
Entity Central Index Key
EntityCentralIndexKey
|
0001771917 | |
CY2023 | dei |
Document Fiscal Period Focus
DocumentFiscalPeriodFocus
|
FY | |
CY2023 | dei |
Amendment Flag
AmendmentFlag
|
false | |
CY2023 | dei |
Current Fiscal Year End Date
CurrentFiscalYearEndDate
|
--12-31 | |
CY2022Q4 | us-gaap |
Commitments And Contingencies
CommitmentsAndContingencies
|
||
CY2023Q4 | us-gaap |
Commitments And Contingencies
CommitmentsAndContingencies
|
||
CY2023 | krtx |
Share Based Compensation Arrangement By Share Based Payment Award Termination Date
ShareBasedCompensationArrangementByShareBasedPaymentAwardTerminationDate
|
2019-07-02 | |
CY2023 | dei |
Document Type
DocumentType
|
10-K | |
CY2023 | dei |
Document Annual Report
DocumentAnnualReport
|
true | |
CY2023 | dei |
Document Period End Date
DocumentPeriodEndDate
|
2023-12-31 | |
CY2023 | dei |
Document Fiscal Year Focus
DocumentFiscalYearFocus
|
2023 | |
CY2023 | dei |
Document Transition Report
DocumentTransitionReport
|
false | |
CY2023 | dei |
Entity File Number
EntityFileNumber
|
001-38958 | |
CY2023 | dei |
Entity Registrant Name
EntityRegistrantName
|
Karuna Therapeutics, Inc. | |
CY2023 | dei |
Entity Incorporation State Country Code
EntityIncorporationStateCountryCode
|
DE | |
CY2023 | dei |
Entity Tax Identification Number
EntityTaxIdentificationNumber
|
27-0605902 | |
CY2023 | dei |
Entity Address Address Line1
EntityAddressAddressLine1
|
99 High Street | |
CY2023 | dei |
Entity Address Address Line2
EntityAddressAddressLine2
|
26th Floor | |
CY2023 | dei |
Entity Address City Or Town
EntityAddressCityOrTown
|
Boston | |
CY2023 | dei |
Entity Address State Or Province
EntityAddressStateOrProvince
|
MA | |
CY2023 | dei |
Entity Address Postal Zip Code
EntityAddressPostalZipCode
|
02110 | |
CY2023 | dei |
City Area Code
CityAreaCode
|
857 | |
CY2023 | dei |
Local Phone Number
LocalPhoneNumber
|
449-2244 | |
CY2023 | dei |
Security12b Title
Security12bTitle
|
Common Stock, $0.0001 Par Value | |
CY2023 | dei |
Trading Symbol
TradingSymbol
|
KRTX | |
CY2023 | dei |
Security Exchange Name
SecurityExchangeName
|
NASDAQ | |
CY2023 | dei |
Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
|
Yes | |
CY2023 | dei |
Entity Voluntary Filers
EntityVoluntaryFilers
|
No | |
CY2023 | dei |
Entity Current Reporting Status
EntityCurrentReportingStatus
|
Yes | |
CY2023 | dei |
Entity Interactive Data Current
EntityInteractiveDataCurrent
|
Yes | |
CY2023 | dei |
Entity Filer Category
EntityFilerCategory
|
Large Accelerated Filer | |
CY2023 | dei |
Entity Small Business
EntitySmallBusiness
|
false | |
CY2023 | dei |
Entity Emerging Growth Company
EntityEmergingGrowthCompany
|
false | |
CY2023 | dei |
Icfr Auditor Attestation Flag
IcfrAuditorAttestationFlag
|
true | |
CY2023 | dei |
Document Fin Stmt Error Correction Flag
DocumentFinStmtErrorCorrectionFlag
|
false | |
CY2023 | dei |
Entity Shell Company
EntityShellCompany
|
false | |
CY2023Q2 | dei |
Entity Public Float
EntityPublicFloat
|
5872600000 | |
CY2024Q1 | dei |
Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
|
38147652 | |
CY2023 | dei |
Auditor Name
AuditorName
|
KPMG LLP | |
CY2023 | dei |
Auditor Location
AuditorLocation
|
Boston, Massachusetts | |
CY2023Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
185823000 | |
CY2022Q4 | us-gaap |
Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
|
248329000 | |
CY2023Q4 | us-gaap |
Marketable Securities
MarketableSecurities
|
1074957000 | |
CY2022Q4 | us-gaap |
Marketable Securities
MarketableSecurities
|
875715000 | |
CY2023Q4 | us-gaap |
Other Short Term Investments
OtherShortTermInvestments
|
2033000 | |
CY2022Q4 | us-gaap |
Other Short Term Investments
OtherShortTermInvestments
|
0 | |
CY2023Q4 | us-gaap |
Receivables Net Current
ReceivablesNetCurrent
|
0 | |
CY2022Q4 | us-gaap |
Receivables Net Current
ReceivablesNetCurrent
|
57000 | |
CY2023Q4 | us-gaap |
Prepaid Expense Current
PrepaidExpenseCurrent
|
39993000 | |
CY2022Q4 | us-gaap |
Prepaid Expense Current
PrepaidExpenseCurrent
|
29106000 | |
CY2023Q4 | us-gaap |
Other Assets Current
OtherAssetsCurrent
|
12507000 | |
CY2022Q4 | us-gaap |
Other Assets Current
OtherAssetsCurrent
|
1562000 | |
CY2023Q4 | us-gaap |
Assets Current
AssetsCurrent
|
1315313000 | |
CY2022Q4 | us-gaap |
Assets Current
AssetsCurrent
|
1154769000 | |
CY2023Q4 | us-gaap |
Restricted Cash Noncurrent
RestrictedCashNoncurrent
|
0 | |
CY2022Q4 | us-gaap |
Restricted Cash Noncurrent
RestrictedCashNoncurrent
|
261000 | |
CY2023Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
15090000 | |
CY2022Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
4674000 | |
CY2023Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
5424000 | |
CY2022Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
3201000 | |
CY2023Q4 | us-gaap |
Other Assets Noncurrent
OtherAssetsNoncurrent
|
382000 | |
CY2022Q4 | us-gaap |
Other Assets Noncurrent
OtherAssetsNoncurrent
|
429000 | |
CY2023Q4 | us-gaap |
Assets
Assets
|
1336209000 | |
CY2022Q4 | us-gaap |
Assets
Assets
|
1163334000 | |
CY2023Q4 | us-gaap |
Accounts Payable Current
AccountsPayableCurrent
|
6783000 | |
CY2022Q4 | us-gaap |
Accounts Payable Current
AccountsPayableCurrent
|
2379000 | |
CY2023Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
41609000 | |
CY2022Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
29285000 | |
CY2023Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
2843000 | |
CY2022Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
2282000 | |
CY2023Q4 | us-gaap |
Other Liabilities Current
OtherLiabilitiesCurrent
|
16894000 | |
CY2022Q4 | us-gaap |
Other Liabilities Current
OtherLiabilitiesCurrent
|
0 | |
CY2023Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
68129000 | |
CY2022Q4 | us-gaap |
Liabilities Current
LiabilitiesCurrent
|
33946000 | |
CY2023Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
13845000 | |
CY2022Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
3046000 | |
CY2023Q4 | us-gaap |
Other Liabilities Noncurrent
OtherLiabilitiesNoncurrent
|
0 | |
CY2022Q4 | us-gaap |
Other Liabilities Noncurrent
OtherLiabilitiesNoncurrent
|
104000 | |
CY2023Q4 | us-gaap |
Liabilities
Liabilities
|
81974000 | |
CY2022Q4 | us-gaap |
Liabilities
Liabilities
|
37096000 | |
CY2023Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.0001 | |
CY2022Q4 | us-gaap |
Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
|
0.0001 | |
CY2023Q4 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
10000000 | |
CY2022Q4 | us-gaap |
Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
|
10000000 | |
CY2023Q4 | us-gaap |
Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
|
0 | |
CY2022Q4 | us-gaap |
Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
|
0 | |
CY2023Q4 | us-gaap |
Preferred Stock Value
PreferredStockValue
|
0 | |
CY2022Q4 | us-gaap |
Preferred Stock Value
PreferredStockValue
|
0 | |
CY2023Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.0001 | |
CY2022Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.0001 | |
CY2023Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
150000000 | |
CY2022Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
150000000 | |
CY2023Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
38091829 | |
CY2022Q4 | us-gaap |
Common Stock Shares Issued
CommonStockSharesIssued
|
34473905 | |
CY2023Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
38077525 | |
CY2022Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
34473905 | |
CY2023Q4 | us-gaap |
Common Stock Value
CommonStockValue
|
4000 | |
CY2022Q4 | us-gaap |
Common Stock Value
CommonStockValue
|
3000 | |
CY2023Q4 | us-gaap |
Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
|
2256431000 | |
CY2022Q4 | us-gaap |
Additional Paid In Capital Common Stock
AdditionalPaidInCapitalCommonStock
|
1693732000 | |
CY2023Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-997887000 | |
CY2022Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-564207000 | |
CY2023Q4 | us-gaap |
Aoci Before Tax Attributable To Parent
AociBeforeTaxAttributableToParent
|
211000 | |
CY2022Q4 | us-gaap |
Aoci Before Tax Attributable To Parent
AociBeforeTaxAttributableToParent
|
-3290000 | |
CY2023Q4 | us-gaap |
Treasury Stock Common Shares
TreasuryStockCommonShares
|
14304 | |
CY2022Q4 | us-gaap |
Treasury Stock Common Shares
TreasuryStockCommonShares
|
0 | |
CY2023Q4 | us-gaap |
Treasury Stock Value
TreasuryStockValue
|
4524000 | |
CY2022Q4 | us-gaap |
Treasury Stock Value
TreasuryStockValue
|
0 | |
CY2023Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
1254235000 | |
CY2022Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
1126238000 | |
CY2023Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
1336209000 | |
CY2022Q4 | us-gaap |
Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
|
1163334000 | |
CY2023 | us-gaap |
Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
|
654000 | |
CY2022 | us-gaap |
Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
|
10637000 | |
CY2021 | us-gaap |
Revenue From Contract With Customer Including Assessed Tax
RevenueFromContractWithCustomerIncludingAssessedTax
|
36964000 | |
CY2023 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
364101000 | |
CY2022 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
224247000 | |
CY2021 | us-gaap |
Research And Development Expense
ResearchAndDevelopmentExpense
|
128200000 | |
CY2023 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
131330000 | |
CY2022 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
76066000 | |
CY2021 | us-gaap |
General And Administrative Expense
GeneralAndAdministrativeExpense
|
52617000 | |
CY2023 | us-gaap |
Operating Expenses
OperatingExpenses
|
495431000 | |
CY2022 | us-gaap |
Operating Expenses
OperatingExpenses
|
300313000 | |
CY2021 | us-gaap |
Operating Expenses
OperatingExpenses
|
180817000 | |
CY2023 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-494777000 | |
CY2022 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-289676000 | |
CY2021 | us-gaap |
Operating Income Loss
OperatingIncomeLoss
|
-143853000 | |
CY2021 | us-gaap |
Other Comprehensive Income Loss Before Tax Portion Attributable To Parent
OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent
|
-536000 | |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-143805000 | |
CY2021Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
502026000 | |
CY2023 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
61179000 | |
CY2022 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
14178000 | |
CY2021 | us-gaap |
Interest Income Expense Nonoperating Net
InterestIncomeExpenseNonoperatingNet
|
502000 | |
CY2023 | us-gaap |
Sublease Income
SubleaseIncome
|
588000 | |
CY2022 | us-gaap |
Sublease Income
SubleaseIncome
|
580000 | |
CY2021 | us-gaap |
Sublease Income
SubleaseIncome
|
254000 | |
CY2023 | us-gaap |
Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
|
0 | |
CY2022 | us-gaap |
Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
|
0 | |
CY2021 | us-gaap |
Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
|
702000 | |
CY2023 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
61767000 | |
CY2022 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
14758000 | |
CY2021 | us-gaap |
Nonoperating Income Expense
NonoperatingIncomeExpense
|
54000 | |
CY2023 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-433010000 | |
CY2022 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-274918000 | |
CY2021 | us-gaap |
Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest
IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
|
-143799000 | |
CY2023 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
670000 | |
CY2022 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
1418000 | |
CY2021 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
6000 | |
CY2023 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-433680000 | |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-276336000 | |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-143805000 | |
CY2023 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-11.73 | |
CY2023 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-11.73 | |
CY2022 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-8.74 | |
CY2022 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-8.74 | |
CY2021 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-4.94 | |
CY2021 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-4.94 | |
CY2023 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
36959049 | |
CY2023 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
36959049 | |
CY2022 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
31629013 | |
CY2022 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
31629013 | |
CY2021 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
29138915 | |
CY2021 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
29138915 | |
CY2023 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-433680000 | |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-276336000 | |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-143805000 | |
CY2023 | us-gaap |
Other Comprehensive Income Availableforsale Securities Adjustment Before Tax Portion Attributable To Parent
OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentBeforeTaxPortionAttributableToParent
|
3501000 | |
CY2022 | us-gaap |
Other Comprehensive Income Availableforsale Securities Adjustment Before Tax Portion Attributable To Parent
OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentBeforeTaxPortionAttributableToParent
|
-2793000 | |
CY2021 | us-gaap |
Other Comprehensive Income Availableforsale Securities Adjustment Before Tax Portion Attributable To Parent
OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentBeforeTaxPortionAttributableToParent
|
-536000 | |
CY2023 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-430179000 | |
CY2022 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-279129000 | |
CY2021 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-144341000 | |
CY2020Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
338931000 | |
CY2021 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
270017000 | |
CY2021 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
29811000 | |
CY2021 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
7608000 | |
CY2022 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
819047000 | |
CY2022 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
47451000 | |
CY2022 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
36843000 | |
CY2022 | us-gaap |
Other Comprehensive Income Loss Before Tax Portion Attributable To Parent
OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent
|
-2793000 | |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-276336000 | |
CY2022Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
1126238000 | |
CY2023 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
436720000 | |
CY2023 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
74599000 | |
CY2023 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
51381000 | |
CY2023 | krtx |
Shares To Cover Employee Payroll Tax Withholdings On Stock Issued Under Benefit Plans Values
SharesToCoverEmployeePayrollTaxWithholdingsOnStockIssuedUnderBenefitPlansValues
|
-4524000 | |
CY2023 | us-gaap |
Other Comprehensive Income Loss Before Tax Portion Attributable To Parent
OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent
|
3501000 | |
CY2023 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-433680000 | |
CY2023Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
1254235000 | |
CY2023 | us-gaap |
Profit Loss
ProfitLoss
|
-433680000 | |
CY2022 | us-gaap |
Profit Loss
ProfitLoss
|
-276336000 | |
CY2021 | us-gaap |
Profit Loss
ProfitLoss
|
-143805000 | |
CY2023 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
74599000 | |
CY2022 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
47451000 | |
CY2021 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
29811000 | |
CY2023 | us-gaap |
Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
|
0 | |
CY2022 | us-gaap |
Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
|
0 | |
CY2021 | us-gaap |
Operating Lease Impairment Loss
OperatingLeaseImpairmentLoss
|
702000 | |
CY2023 | us-gaap |
Accretion Amortization Of Discounts And Premiums Investments
AccretionAmortizationOfDiscountsAndPremiumsInvestments
|
37966000 | |
CY2022 | us-gaap |
Accretion Amortization Of Discounts And Premiums Investments
AccretionAmortizationOfDiscountsAndPremiumsInvestments
|
5007000 | |
CY2021 | us-gaap |
Accretion Amortization Of Discounts And Premiums Investments
AccretionAmortizationOfDiscountsAndPremiumsInvestments
|
-1063000 | |
CY2023 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
1701000 | |
CY2022 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
1112000 | |
CY2021 | us-gaap |
Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
|
506000 | |
CY2023 | krtx |
Increase Decrease In Accrued Interest On Investment Securities
IncreaseDecreaseInAccruedInterestOnInvestmentSecurities
|
2404000 | |
CY2022 | krtx |
Increase Decrease In Accrued Interest On Investment Securities
IncreaseDecreaseInAccruedInterestOnInvestmentSecurities
|
983000 | |
CY2021 | krtx |
Increase Decrease In Accrued Interest On Investment Securities
IncreaseDecreaseInAccruedInterestOnInvestmentSecurities
|
-261000 | |
CY2023 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
-57000 | |
CY2022 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
-1693000 | |
CY2021 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
1750000 | |
CY2023 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
10887000 | |
CY2022 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
8040000 | |
CY2021 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
-283000 | |
CY2023 | us-gaap |
Increase Decrease In Other Current Assets
IncreaseDecreaseInOtherCurrentAssets
|
10741000 | |
CY2022 | us-gaap |
Increase Decrease In Other Current Assets
IncreaseDecreaseInOtherCurrentAssets
|
922000 | |
CY2021 | us-gaap |
Increase Decrease In Other Current Assets
IncreaseDecreaseInOtherCurrentAssets
|
-443000 | |
CY2023 | krtx |
Increase Decrease In Right Of Use Assets
IncreaseDecreaseInRightOfUseAssets
|
-2903000 | |
CY2022 | krtx |
Increase Decrease In Right Of Use Assets
IncreaseDecreaseInRightOfUseAssets
|
-1779000 | |
CY2021 | krtx |
Increase Decrease In Right Of Use Assets
IncreaseDecreaseInRightOfUseAssets
|
-1305000 | |
CY2023 | us-gaap |
Increase Decrease In Other Noncurrent Assets
IncreaseDecreaseInOtherNoncurrentAssets
|
-47000 | |
CY2022 | us-gaap |
Increase Decrease In Other Noncurrent Assets
IncreaseDecreaseInOtherNoncurrentAssets
|
-102000 | |
CY2021 | us-gaap |
Increase Decrease In Other Noncurrent Assets
IncreaseDecreaseInOtherNoncurrentAssets
|
531000 | |
CY2023 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
4347000 | |
CY2022 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
243000 | |
CY2021 | us-gaap |
Increase Decrease In Accounts Payable
IncreaseDecreaseInAccountsPayable
|
1071000 | |
CY2023 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
11374000 | |
CY2022 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
13077000 | |
CY2021 | us-gaap |
Increase Decrease In Accrued Liabilities
IncreaseDecreaseInAccruedLiabilities
|
10881000 | |
CY2023 | us-gaap |
Increase Decrease In Other Current Liabilities
IncreaseDecreaseInOtherCurrentLiabilities
|
16894000 | |
CY2022 | us-gaap |
Increase Decrease In Other Current Liabilities
IncreaseDecreaseInOtherCurrentLiabilities
|
0 | |
CY2021 | us-gaap |
Increase Decrease In Other Current Liabilities
IncreaseDecreaseInOtherCurrentLiabilities
|
0 | |
CY2023 | us-gaap |
Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
|
-1959000 | |
CY2022 | us-gaap |
Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
|
-2175000 | |
CY2021 | us-gaap |
Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
|
-1222000 | |
CY2023 | us-gaap |
Increase Decrease In Other Noncurrent Liabilities
IncreaseDecreaseInOtherNoncurrentLiabilities
|
-104000 | |
CY2022 | us-gaap |
Increase Decrease In Other Noncurrent Liabilities
IncreaseDecreaseInOtherNoncurrentLiabilities
|
0 | |
CY2021 | us-gaap |
Increase Decrease In Other Noncurrent Liabilities
IncreaseDecreaseInOtherNoncurrentLiabilities
|
104000 | |
CY2023 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-385819000 | |
CY2022 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-228006000 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-100878000 | |
CY2023 | us-gaap |
Payments To Acquire Investments
PaymentsToAcquireInvestments
|
1518495000 | |
CY2022 | us-gaap |
Payments To Acquire Investments
PaymentsToAcquireInvestments
|
930280000 | |
CY2021 | us-gaap |
Payments To Acquire Investments
PaymentsToAcquireInvestments
|
400829000 | |
CY2023 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
2033000 | |
CY2022 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
0 | |
CY2021 | us-gaap |
Payments To Acquire Short Term Investments
PaymentsToAcquireShortTermInvestments
|
0 | |
CY2023 | us-gaap |
Proceeds From Maturities Prepayments And Calls Of Available For Sale Securities
ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
|
1363124000 | |
CY2022 | us-gaap |
Proceeds From Maturities Prepayments And Calls Of Available For Sale Securities
ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
|
344800000 | |
CY2021 | us-gaap |
Proceeds From Maturities Prepayments And Calls Of Available For Sale Securities
ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities
|
372223000 | |
CY2023 | krtx |
Proceeds From Sale Of Investment Securities
ProceedsFromSaleOfInvestmentSecurities
|
0 | |
CY2022 | krtx |
Proceeds From Sale Of Investment Securities
ProceedsFromSaleOfInvestmentSecurities
|
0 | |
CY2021 | krtx |
Proceeds From Sale Of Investment Securities
ProceedsFromSaleOfInvestmentSecurities
|
8990000 | |
CY2023 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
2917000 | |
CY2022 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
915000 | |
CY2021 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
3072000 | |
CY2023 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-160321000 | |
CY2022 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-586395000 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-22688000 | |
CY2023 | krtx |
Proceeds From Issuance Of Public Offering Net In Underwriting Discounts And Commissions
ProceedsFromIssuanceOfPublicOfferingNetInUnderwritingDiscountsAndCommissions
|
436720000 | |
CY2022 | krtx |
Proceeds From Issuance Of Public Offering Net In Underwriting Discounts And Commissions
ProceedsFromIssuanceOfPublicOfferingNetInUnderwritingDiscountsAndCommissions
|
819375000 | |
CY2021 | krtx |
Proceeds From Issuance Of Public Offering Net In Underwriting Discounts And Commissions
ProceedsFromIssuanceOfPublicOfferingNetInUnderwritingDiscountsAndCommissions
|
270250000 | |
CY2023 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
204000 | |
CY2022 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
441000 | |
CY2021 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
283000 | |
CY2023 | krtx |
Purchase Of Shares To Cover Employee Payroll Tax Withholdings On Stock Issued
PurchaseOfSharesToCoverEmployeePayrollTaxWithholdingsOnStockIssued
|
4524000 | |
CY2022 | krtx |
Purchase Of Shares To Cover Employee Payroll Tax Withholdings On Stock Issued
PurchaseOfSharesToCoverEmployeePayrollTaxWithholdingsOnStockIssued
|
0 | |
CY2021 | krtx |
Purchase Of Shares To Cover Employee Payroll Tax Withholdings On Stock Issued
PurchaseOfSharesToCoverEmployeePayrollTaxWithholdingsOnStockIssued
|
0 | |
CY2023 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
51381000 | |
CY2022 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
36843000 | |
CY2021 | us-gaap |
Proceeds From Stock Options Exercised
ProceedsFromStockOptionsExercised
|
7608000 | |
CY2023 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
483373000 | |
CY2022 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
855777000 | |
CY2021 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
277575000 | |
CY2023 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
-62767000 | |
CY2022 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
41376000 | |
CY2021 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
154009000 | |
CY2022Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
248590000 | |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
207214000 | |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
53205000 | |
CY2023Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
185823000 | |
CY2022Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
248590000 | |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsIncludingDisposalGroupAndDiscontinuedOperations
|
207214000 | |
CY2023 | krtx |
Operating Lease Liabilities Arising From Obtaining Right Of Use Assets
OperatingLeaseLiabilitiesArisingFromObtainingRightOfUseAssets
|
13319000 | |
CY2022 | krtx |
Operating Lease Liabilities Arising From Obtaining Right Of Use Assets
OperatingLeaseLiabilitiesArisingFromObtainingRightOfUseAssets
|
0 | |
CY2021 | krtx |
Operating Lease Liabilities Arising From Obtaining Right Of Use Assets
OperatingLeaseLiabilitiesArisingFromObtainingRightOfUseAssets
|
6040000 | |
CY2023 | krtx |
Purchases Of Property And Equipment Included In Accounts Payable And Accrued Expenses
PurchasesOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpenses
|
1007000 | |
CY2022 | krtx |
Purchases Of Property And Equipment Included In Accounts Payable And Accrued Expenses
PurchasesOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpenses
|
306000 | |
CY2021 | krtx |
Purchases Of Property And Equipment Included In Accounts Payable And Accrued Expenses
PurchasesOfPropertyAndEquipmentIncludedInAccountsPayableAndAccruedExpenses
|
77000 | |
CY2023 | us-gaap |
Nature Of Operations
NatureOfOperations
|
<p style="font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-weight:bold;font-size:11pt;font-family:Arial;font-style:italic;min-width:fit-content;">Note 1. Nature of the Business</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:6pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-weight:bold;font-size:11pt;font-family:Arial;font-style:italic;min-width:fit-content;">Description of the Business</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:6pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">Karuna Therapeutics, Inc. (the “Company”) was incorporated under the laws of the State of Delaware in July 2009 as Karuna Pharmaceuticals, Inc. and is headquartered in Boston, Massachusetts. In March 2019, the Company changed its name to Karuna Therapeutics, Inc. The Company is a clinical-stage biopharmaceutical company driven to discover, develop, and deliver transformative medicines for people living with psychiatric and neurological conditions.</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">Since the Company’s inception, it has focused substantially all of its efforts and financial resources on organizing and staffing the Company, acquiring and developing its technology, raising capital, building its intellectual property portfolio, undertaking preclinical studies and clinical trials, preparing for the potential commercialization of KarXT, and providing general and administrative support for these activities. The Company has not generated any product revenue related to its primary business purpose to date and is subject to a number of risks similar to those of other early stage companies, including dependence on key individuals, regulatory approval of products, uncertainty of market acceptance of products, competition from substitute products and larger companies, compliance with government regulations, protection of proprietary technology, dependence on third parties, product liability, and the need to obtain adequate additional financing to fund the development of its product candidates.</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">On July 2, 2020, the Company filed an automatically effective registration statement on Form S-3 (the “Registration Statement”) with the SEC which registers the offering, issuance and sale of an unspecified amount of common stock, preferred stock, debt securities, warrants and/or units of any combination thereof. The Company simultaneously entered into an equity distribution agreement with Goldman Sachs & Co. LLC, as sales agent, to provide for the issuance and sale by the Company of up to $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">150.0</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million of common stock from time to time in “at-the-market” offerings under the Registration Statement and related prospectus filed with the Registration Statement (the “ATM Program”). On June 21, 2023, the Company and Goldman Sachs & Co. LLC mutually terminated the Equity Distribution Agreement between the parties dated July 2, 2020 (the “Distribution Agreement”) in connection with the upcoming expiration of the Company's automatic shelf Registration Statement on Form S-3 (File No. 333-239657) filed with the Securities and Exchange Commission on July 2, 2020 (the “Existing Form S-3”). As of </span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">December 31, 2023</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">, </span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">no</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> sales had been made pursuant to the ATM Program.</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">On March 4, 2021, the Company completed a follow-on public offering under the Registration Statement and a related prospectus supplement in which it issued and sold </span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">2,395,834</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> shares of common stock, including full exercise of the underwriters’ over-allotment option to purchase an additional </span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">312,500</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> shares of common stock, at a public offering price of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">120</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> per share. The aggregate net proceeds to the Company from the offering, inclusive of proceeds from the over-allotment exercise, were $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">270.0</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million after deducting underwriting discounts and commissions of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">17.3</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million and offering expenses of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">0.2</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million.</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">On August 9, 2022, the Company completed a follow-on public offering under the Registration Statement and a related prospectus supplement in which it issued and sold </span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">4,011,628</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> shares of common stock, including full exercise of the underwriters’ over-allotment option to purchase an additional </span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">523,255</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> shares of common stock, at a public offering price of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">215</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> per share. The aggregate net proceeds to the Company from the offering, inclusive of proceeds from the over-allotment exercise, were $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">819.1</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million after deducting underwriting discounts and commissions of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">43.1</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million and offering expenses of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">0.3</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million.</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">On March 21, 2023, the Company completed a follow-on public offering under the Registration Statement and a related prospectus supplement in which it issued and sold </span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">2,851,299</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> shares of common stock, which included the full exercise of the underwriters’ option to purchase an additional </span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">371,908</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> shares of common stock, at a public offering price of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">161.33</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> per share. The aggregate net proceeds to the Company from the offering, inclusive of proceeds from the option exercise, were $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">436.7</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million after deducting underwriting discounts and commissions of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">23.0</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million and offering expenses of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">0.3</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million.</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">On June 21, 2023, the Company filed an automatically effective registration statement on Form S-3 (the "2023 Registration Statement"), with the SEC which registers the offering, issuance and sale of an unspecified amount of common stock, preferred stock, debt securities, warrants and/or units of any combination thereof. The Company simultaneously entered into an equity distribution agreement (the "2023 Distribution Agreement"), with Goldman Sachs & Co. LLC and Leerink Partners (f/k/a SVB Securities LLC), as sales agents, to provide for the issuance and sale by the Company of up to $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">400.0</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million of common stock from time to time in “at-the-market” offerings under the 2023 Registration Statement and related prospectus (the "2023 ATM Program"). The Company may sell common stock pursuant to the 2023 Distribution Agreement from time to time in varying amounts, which may be limited, based upon factors including (among others) market conditions, investor demand, the trading price of our common stock, and determinations by us of our need for, and appropriate sources of, additional capital. As of </span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">December 31, 2023, no sales had been made pursuant to the 2023 ATM Program.</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">The Company’s consolidated financial statements have been prepared on the basis of continuity of operations, realization of assets and the satisfaction of liabilities in the ordinary course of business. The Company experienced negative operating cash flows of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">385.8</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million for the year ended December 31, 2023</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> and had an accumulated deficit of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">997.9</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million as of December 31, 2023. The Company expects to continue to generate negative operating cash flows for the foreseeable future.</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">The Company expects that its cash, cash equivalents and available-for-sale investments of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">1,260.8</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million as of December 31, 2023 will be sufficient to fund its operating expenses and capital expenditure requirements through at least 12 months from the date of issuance of these consolidated financial statements.</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-weight:bold;font-size:11pt;font-family:Arial;font-style:italic;min-width:fit-content;">Proposed Transaction with Bristol-Myers Squibb Company</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:6pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">On December 22, 2023, the Company entered into an Agreement and Plan of Merger ("Merger Agreement") with Bristol-Myers Squibb Company ("Bristol Myers Squibb"), and Miramar Merger Sub Inc., a wholly owned subsidiary of Bristol Myers Squibb ("Merger Sub"), pursuant to which, on the terms and subject to the conditions set forth in the Merger Agreement, Merger Sub will merge with and into the Company, with the Company continuing as the surviving corporation in such merger (the "Merger") as a wholly owned subsidiary of Bristol Myers Squibb.</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">On the terms and subject to the conditions set forth in the Merger Agreement, at the effective time of the Merger ("Effective Time"), and as a result of the Merger, each share of the Company's common stock that is issued and outstanding immediately prior to the Effective Time (other than (i) shares of our common Stock owned by Bristol Myers Squibb, Merger Sub or any other wholly owned subsidiary of Bristol Myers Squibb, immediately prior to the Effective Time and shares of the Company's common stock owned by the Company immediately prior the Effective Time, including shares of the Company's common stock held in treasury by the Company, and in each case not held on behalf of third parties, and (ii) shares of the Company's common stock for which appraisal rights have been properly exercised in accordance with Section 262 of the Delaware General Corporation Law and perfected and not withdrawn) will be converted into the right to receive $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">330</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> in cash, without interest, and less any applicable withholding taxes (the “Merger Consideration”).</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">Immediately prior to the Effective Time, each outstanding and unexercised option to purchase shares of the Company's common stock (an “Option”), whether granted under a Company stock plan or otherwise, will, automatically and without any required action on the part of the holder thereof, become immediately vested and be cancelled and will only entitle the holder of such Option to receive (without interest), at or promptly after the Effective Time, a one-time lump sum payment in an amount in cash equal to (i) the total number of shares of common stock subject to such Option multiplied by (ii) the excess, if any, of the Merger Consideration over the exercise price per share of the common stock under such Option, less applicable taxes required to be withheld with respect to such payment. For the avoidance of doubt, any Option which has a per share exercise price that is greater than or equal to the Merger Consideration shall be cancelled at the Effective Time for no consideration or payment and shall have no further force or effect.</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">Immediately prior to the Effective Time, each outstanding restricted stock unit (“Company RSU”), whether granted under a Company stock plan or otherwise, shall, automatically and without any required action on the part of the holder thereof, become immediately vested and be cancelled and shall only entitle the holder of such Company RSU to receive (without interest), at or promptly after the Effective Time, a one-time lump sum payment in an amount in cash equal to (i) the total number of shares of common stock subject to such Company RSU immediately prior to the Effective Time multiplied by (ii) the Merger Consideration, less applicable taxes required to be withheld with respect to such payment.</span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">Consummation of the Merger is subject to certain customary conditions, including (i) the approval of the Merger by the holders of a majority of the outstanding shares of the Company's common stock, (ii) the absence of any law prohibiting or order preventing the consummation of the Merger, (iii) the receipt of certain regulatory approvals, to the extent required, including the expiration or early termination of the applicable waiting period (or any extension thereof) under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, and (iv) compliance in all material respects on the part of each of the Company, Bristol Myers Squibb and Merger Sub with such party’s covenants under the Merger Agreement. The obligation of each party to consummate the Merger is also conditioned upon the other party’s representations and warranties being true and correct (subject to certain materiality exceptions), and upon no “Material Adverse Effect” (as defined in the Merger Agreement) having occurred with respect to the Company since the signing of the Merger Agreement.</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">Subject to the satisfaction of such closing conditions, the Company anticipates the Merger and the other transactions contemplated by the Merger Agreement to close in the first half of 2024. Following completion of the Merger, the Company's common stock will no longer be publicly listed.</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span></p><p style="text-indent:4.533%;font-size:10pt;margin-top:12pt;font-family:Times New Roman;margin-bottom:0;text-align:left;"><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;">The Company and Bristol Myers Squibb have certain customary termination rights pursuant to the Merger Agreement, including the Company's right to terminate the Merger Agreement to accept a “Superior Proposal” (as defined in the Merger Agreement) subject to compliance with certain procedures specified in the Merger Agreement. If the Merger Agreement is terminated under certain specified circumstances set forth in the Merger Agreement, the Company will be required to pay Bristol Myers Squibb a termination fee of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">490</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million. If the Merger Agreement is terminated under other specified circumstances set forth in the Merger Agreement, Bristol Myers Squibb will be required to pay the Company a termination fee of $</span><span style="font-size:11pt;font-family:Arial;color:#000000;white-space:pre-wrap;min-width:fit-content;">600</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> million.</span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span><span style="color:#000000;white-space:pre-wrap;font-size:11pt;font-family:Arial;min-width:fit-content;"> </span></p> | |
CY2021Q1 | krtx |
Proceeds From Issuance Public Offering
ProceedsFromIssuancePublicOffering
|
270000000 | |
CY2021Q1 | krtx |
Underwriting Discounts And Commissions
UnderwritingDiscountsAndCommissions
|
17300000 | |
CY2021Q1 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
200000 | |
CY2022Q3 | krtx |
Proceeds From Issuance Public Offering
ProceedsFromIssuancePublicOffering
|
819100000 | |
CY2022Q3 | krtx |
Underwriting Discounts And Commissions
UnderwritingDiscountsAndCommissions
|
43100000 | |
CY2022Q3 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
300000 | |
CY2023Q1 | us-gaap |
Stock Issued During Period Shares New Issues
StockIssuedDuringPeriodSharesNewIssues
|
2851299 | |
CY2023Q1 | krtx |
Purchase Of Additional Shares
PurchaseOfAdditionalShares
|
371908 | |
CY2023Q1 | krtx |
Proceeds From Issuance Public Offering
ProceedsFromIssuancePublicOffering
|
436700000 | |
CY2023Q1 | krtx |
Underwriting Discounts And Commissions
UnderwritingDiscountsAndCommissions
|
23000000 | |
CY2023Q1 | krtx |
Stock Issurance Costs Incurred
StockIssuranceCostsIncurred
|
300000 | |
CY2023Q2 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
400000000 | |
CY2023 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-385800000 | |
CY2023Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-997900000 | |
CY2023Q4 | krtx |
Cash Cash Equivalents And Available For Sale Investments
CashCashEquivalentsAndAvailableForSaleInvestments
|
1260800000 | |
CY2023 | krtx |
Right To Receive Cash Without Interest
RightToReceiveCashWithoutInterest
|
330000 | |
CY2023 | us-gaap |
Depreciation
Depreciation
|
1700000 | |
CY2022 | us-gaap |
Depreciation
Depreciation
|
1100000 | |
CY2021 | us-gaap |
Depreciation
Depreciation
|
500000 | |
CY2023Q4 | us-gaap |
Deferred Offering Costs
DeferredOfferingCosts
|
200000 | |
CY2022Q4 | us-gaap |
Deferred Offering Costs
DeferredOfferingCosts
|
600000 | |
CY2023Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
8530000 | |
CY2022Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
4881000 | |
CY2023Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
3106000 | |
CY2022Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
1680000 | |
CY2023Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
5424000 | |
CY2022Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
3201000 | |
CY2023Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
150000000 | |
CY2023Q4 | us-gaap |
Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
|
0.0001 | |
CY2023 | us-gaap |
Dividends Common Stock Cash
DividendsCommonStockCash
|
0 | |
CY2023Q4 | us-gaap |
Common Stock Shares Outstanding
CommonStockSharesOutstanding
|
38077525 | |
CY2023Q4 | us-gaap |
Treasury Stock Common Shares
TreasuryStockCommonShares
|
14304 | |
CY2023Q4 | krtx |
Prepaid Research And Development Expenses
PrepaidResearchAndDevelopmentExpenses
|
35868000 | |
CY2022Q4 | krtx |
Prepaid Research And Development Expenses
PrepaidResearchAndDevelopmentExpenses
|
25285000 | |
CY2023Q4 | us-gaap |
Prepaid Insurance
PrepaidInsurance
|
1863000 | |
CY2022Q4 | us-gaap |
Prepaid Insurance
PrepaidInsurance
|
2472000 | |
CY2023Q4 | us-gaap |
Other Assets
OtherAssets
|
2262000 | |
CY2022Q4 | us-gaap |
Other Assets
OtherAssets
|
1349000 | |
CY2023Q4 | us-gaap |
Prepaid Expense Current
PrepaidExpenseCurrent
|
39993000 | |
CY2022Q4 | us-gaap |
Prepaid Expense Current
PrepaidExpenseCurrent
|
29106000 | |
CY2023 | krtx |
Refundable Fee
RefundableFee
|
3200000 | |
CY2022Q4 | us-gaap |
Interest Receivable
InterestReceivable
|
700000 | |
CY2023Q4 | krtx |
Accrued Research And Development Expense Current
AccruedResearchAndDevelopmentExpenseCurrent
|
16172000 | |
CY2022Q4 | krtx |
Accrued Research And Development Expense Current
AccruedResearchAndDevelopmentExpenseCurrent
|
11962000 | |
CY2023Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
15145000 | |
CY2022Q4 | us-gaap |
Employee Related Liabilities Current
EmployeeRelatedLiabilitiesCurrent
|
11950000 | |
CY2023Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
5451000 | |
CY2022Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
2943000 | |
CY2023Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
4841000 | |
CY2022Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
2430000 | |
CY2023Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
41609000 | |
CY2022Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
29285000 | |
CY2023Q4 | us-gaap |
Accrued Payroll Taxes Current
AccruedPayrollTaxesCurrent
|
17100000 | |
CY2022Q4 | us-gaap |
Accrued Payroll Taxes Current
AccruedPayrollTaxesCurrent
|
0 | |
CY2023 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-433680000 | |
CY2022 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-276336000 | |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-143805000 | |
CY2023 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
36959049 | |
CY2023 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
36959049 | |
CY2022 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
31629013 | |
CY2022 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
31629013 | |
CY2021 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
29138915 | |
CY2021 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
29138915 | |
CY2023 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-11.73 | |
CY2023 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-11.73 | |
CY2022 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-8.74 | |
CY2022 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-8.74 | |
CY2021 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-4.94 | |
CY2021 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-4.94 | |
CY2023 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
5555130 | |
CY2022 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
5570355 | |
CY2021 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
5323162 | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
5570355 | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
63.82 | |
CY2022 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P7Y2M12D | |
CY2022Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
744097000 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
|
707004 | |
CY2023 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
|
192.92 | |
CY2023 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
733300 | |
CY2023 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
|
70.07 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
|
304384 | |
CY2023 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
|
143.65 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod
|
2926 | |
CY2023 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice
|
123.93 | |
CY2023Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
5236749 | |
CY2023Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
75.7 | |
CY2023 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P6Y6M | |
CY2023Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
1261077000 | |
CY2023Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
|
5236749 | |
CY2023Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
|
75.7 | |
CY2023 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1
|
P6Y6M | |
CY2023Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue
|
1261077000 | |
CY2023Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
|
3724615 | |
CY2023Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
|
42.63 | |
CY2023 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
|
P5Y7M6D | |
CY2023Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
|
1020087000 | |
CY2023Q4 | us-gaap |
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions
|
121200000 | |
CY2023 | us-gaap |
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1
|
P2Y7M6D | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
113.15 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
79.63 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
71.4 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
116800000 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
106300000 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
40500000 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
|
0.5153 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
|
0.5617 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
|
0.5625 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
|
0.6039 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMinimum
|
0.5657 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRateMaximum
|
0.6021 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
|
0.0344 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
|
0.0471 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
|
0.0147 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
|
0.0419 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Minimum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMinimum
|
0.0057 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate Maximum
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRateMaximum
|
0.0137 | |
CY2023 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | |
CY2022 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | |
CY2023 | krtx |
Operating Lease Liabilities Arising From Obtaining Right Of Use Assets
OperatingLeaseLiabilitiesArisingFromObtainingRightOfUseAssets
|
13319000 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
|
0 | |
CY2023 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
74599000 | |
CY2022 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
47451000 | |
CY2021 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
29811000 | |
CY2023Q4 | krtx |
Available For Sale Securities Amortized Cost Basis
AvailableForSaleSecuritiesAmortizedCostBasis
|
1074746000 | |
CY2023Q4 | krtx |
Available For Sale Securities Accumulated Gross Unrealized Gains Before Tax
AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainsBeforeTax
|
1133000 | |
CY2023Q4 | krtx |
Available For Sale Securities Accumulated Gross Unrealized Losses Before Tax
AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossesBeforeTax
|
922000 | |
CY2023Q4 | krtx |
Available For Sale Securities Fair Value
AvailableForSaleSecuritiesFairValue
|
1074957000 | |
CY2022Q4 | krtx |
Available For Sale Securities Amortized Cost Basis
AvailableForSaleSecuritiesAmortizedCostBasis
|
879005000 | |
CY2022Q4 | krtx |
Available For Sale Securities Accumulated Gross Unrealized Gains Before Tax
AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainsBeforeTax
|
88000 | |
CY2022Q4 | krtx |
Available For Sale Securities Accumulated Gross Unrealized Losses Before Tax
AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossesBeforeTax
|
3378000 | |
CY2022Q4 | krtx |
Available For Sale Securities Fair Value
AvailableForSaleSecuritiesFairValue
|
875715000 | |
CY2023 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
3920000 | |
CY2022 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
2150000 | |
CY2021 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
1829000 | |
CY2023 | us-gaap |
Sublease Income
SubleaseIncome
|
588000 | |
CY2022 | us-gaap |
Sublease Income
SubleaseIncome
|
580000 | |
CY2021 | us-gaap |
Sublease Income
SubleaseIncome
|
254000 | |
CY2023 | us-gaap |
Lease Cost
LeaseCost
|
3332000 | |
CY2022 | us-gaap |
Lease Cost
LeaseCost
|
1570000 | |
CY2021 | us-gaap |
Lease Cost
LeaseCost
|
1575000 | |
CY2023 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
2976000 | |
CY2022 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
2547000 | |
CY2021 | us-gaap |
Operating Lease Payments
OperatingLeasePayments
|
1618000 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.053 | |
CY2022 | krtx |
Operating Lease Liabilities Arising From Obtaining Right Of Use Assets
OperatingLeaseLiabilitiesArisingFromObtainingRightOfUseAssets
|
0 | |
CY2021 | krtx |
Operating Lease Liabilities Arising From Obtaining Right Of Use Assets
OperatingLeaseLiabilitiesArisingFromObtainingRightOfUseAssets
|
6040000 | |
CY2023Q4 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P8Y6M10D | |
CY2022Q4 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P2Y7M24D | |
CY2021Q4 | us-gaap |
Operating Lease Weighted Average Remaining Lease Term1
OperatingLeaseWeightedAverageRemainingLeaseTerm1
|
P3Y6M | |
CY2023Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.1054 | |
CY2022Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.0587 | |
CY2021Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.0590 | |
CY2023Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
|
3044000 | |
CY2023Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
|
4818000 | |
CY2023Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
|
3591000 | |
CY2023Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
|
3698000 | |
CY2023Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
|
3809000 | |
CY2023Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due After Year Five
LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive
|
25379000 | |
CY2023Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
44339000 | |
CY2023Q4 | krtx |
Less Lease Incentive
LessLeaseIncentive
|
-9184000 | |
CY2023Q4 | us-gaap |
Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
|
18467000 | |
CY2023Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
16688000 | |
CY2023Q4 | us-gaap |
Litigation Reserve
LitigationReserve
|
0 | |
CY2023 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
700000 | |
CY2022 | us-gaap |
Income Tax Expense Benefit
IncomeTaxExpenseBenefit
|
1400000 | |
CY2023 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.21 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.21 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.21 | |
CY2023 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.049 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.073 | |
CY2023 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0.037 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0.056 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0.036 | |
CY2023 | krtx |
Effective Income Taxrate Reconciliation Nondeductible Foreign Withholding Tax
EffectiveIncomeTaxrateReconciliationNondeductibleForeignWithholdingTax
|
0 | |
CY2022 | krtx |
Effective Income Taxrate Reconciliation Nondeductible Foreign Withholding Tax
EffectiveIncomeTaxrateReconciliationNondeductibleForeignWithholdingTax
|
-0.003 | |
CY2021 | krtx |
Effective Income Taxrate Reconciliation Nondeductible Foreign Withholding Tax
EffectiveIncomeTaxrateReconciliationNondeductibleForeignWithholdingTax
|
0 | |
CY2023 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.05 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.082 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits
EffectiveIncomeTaxRateReconciliationTaxCredits
|
0.052 | |
CY2023 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.34 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.422 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.351 | |
CY2023 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
-0.007 | |
CY2022 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
-0.001 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
0 | |
CY2023 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
-0.002 | |
CY2022 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
-0.005 | |
CY2021 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0 | |
CY2023Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
149855000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
105911000 | |
CY2023Q4 | us-gaap |
Deferred Tax Liabilities Deferred Expense Capitalized Research And Development Costs
DeferredTaxLiabilitiesDeferredExpenseCapitalizedResearchAndDevelopmentCosts
|
124697000 | |
CY2022Q4 | us-gaap |
Deferred Tax Liabilities Deferred Expense Capitalized Research And Development Costs
DeferredTaxLiabilitiesDeferredExpenseCapitalizedResearchAndDevelopmentCosts
|
59654000 | |
CY2023Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards
DeferredTaxAssetsTaxCreditCarryforwards
|
63377000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards
DeferredTaxAssetsTaxCreditCarryforwards
|
38840000 | |
CY2023Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
|
25535000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense Compensation And Benefits Share Based Compensation Cost
DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost
|
18457000 | |
CY2023Q4 | krtx |
Deferred Tax Assets Accrued Expenses
DeferredTaxAssetsAccruedExpenses
|
5640000 | |
CY2022Q4 | krtx |
Deferred Tax Assets Accrued Expenses
DeferredTaxAssetsAccruedExpenses
|
2745000 | |
CY2023Q4 | krtx |
Deferred Tax Assets Lease Liability
DeferredTaxAssetsLeaseLiability
|
4154000 | |
CY2022Q4 | krtx |
Deferred Tax Assets Lease Liability
DeferredTaxAssetsLeaseLiability
|
1371000 | |
CY2023Q4 | krtx |
Deferred Tax Assets Tax Deferred Expense Charitable Contributions
DeferredTaxAssetsTaxDeferredExpenseCharitableContributions
|
182000 | |
CY2022Q4 | krtx |
Deferred Tax Assets Tax Deferred Expense Charitable Contributions
DeferredTaxAssetsTaxDeferredExpenseCharitableContributions
|
188000 | |
CY2023Q4 | krtx |
Deferred Tax Assets Depreciation And Amortization
DeferredTaxAssetsDepreciationAndAmortization
|
3569000 | |
CY2022Q4 | krtx |
Deferred Tax Assets Depreciation And Amortization
DeferredTaxAssetsDepreciationAndAmortization
|
10000 | |
CY2023Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
377009000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
227176000 | |
CY2023Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
373253000 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
225973000 | |
CY2023Q4 | krtx |
Deferred Tax Liabilities Right Of Use Assets
DeferredTaxLiabilitiesRightOfUseAssets
|
3756000 | |
CY2022Q4 | krtx |
Deferred Tax Liabilities Right Of Use Assets
DeferredTaxLiabilitiesRightOfUseAssets
|
1203000 | |
CY2023Q4 | us-gaap |
Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
|
3756000 | |
CY2022Q4 | us-gaap |
Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
|
1203000 | |
CY2023Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
0 | |
CY2022Q4 | us-gaap |
Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
|
0 | |
CY2023 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
147300000 | |
CY2023 | krtx |
Period Of Cumulative Changes In Ownership Interests
PeriodOfCumulativeChangesInOwnershipInterests
|
P3Y | |
CY2023Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
0 | |
CY2023Q4 | us-gaap |
Unrecognized Tax Benefits Income Tax Penalties And Interest Accrued
UnrecognizedTaxBenefitsIncomeTaxPenaltiesAndInterestAccrued
|
0 | |
CY2023 | krtx |
Defined Contribution Plan Name
DefinedContributionPlanName
|
401(k) | |
CY2023 | us-gaap |
Defined Contribution Plan Cost Recognized
DefinedContributionPlanCostRecognized
|
2000000 | |
CY2022 | us-gaap |
Defined Contribution Plan Cost Recognized
DefinedContributionPlanCostRecognized
|
1000000 | |
CY2021 | us-gaap |
Defined Contribution Plan Cost Recognized
DefinedContributionPlanCostRecognized
|
500000 | |
CY2023 | dei |
Auditor Firm
AuditorFirmId
|
185 |