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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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|---|---|---|---|---|
| Cash flows from operating activities: | ||||
| Net loss | ||||
| Adjustments to reconcile net loss to net cash used in operating activities: | ||||
| Share-based compensation expense | ||||
| Depreciation and amortization expense | ||||
| Non-cash lease expense | ||||
| Non-cash interest expense | ||||
| Accretion of discounts on investments, net | ||||
| Deferred tax provision (benefit) | ||||
| Foreign exchange loss | ||||
| Common shares issued to acquire in-process research & development | ||||
| Other | ||||
| Changes in operating assets and liabilities: | ||||
| Accounts receivable | ||||
| Prepaid expenses and other current assets | ||||
| Operating lease right-of-use assets | ||||
| Other non-current assets | ||||
| Accounts payable | ||||
| Accrued expenses and other current liabilities | ||||
| Deferred revenue | ||||
| Income taxes payable | ||||
| Operating lease liabilities | ||||
| Net cash used in operating activities | ||||
| Cash flows from investing activities: | ||||
| Purchases of investments | ||||
| Maturities of investments | ||||
| Purchases of property and equipment | ||||
| Net cash (used in) provided by investing activities | ||||
| Cash flows from financing activities: | ||||
| Proceeds from issuance of debt | ||||
| Proceeds from issuance of common shares from private placements | ||||
| Proceeds from issuance of common shares from at-the-market offering, net of issuance costs | ||||
| Payment of offering costs | ||||
| Proceeds from issuance of common shares upon exercise of stock options and ESPP | ||||
| Net cash provided by financing activities | ||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | ||||
| Cash, cash equivalents and restricted cash at beginning of period | ||||
| Cash, cash equivalents and restricted cash at end of period | ||||
| Supplemental disclosure of cash flow information: | ||||
| Cash paid for income taxes | ||||
| Cash paid for interest | ||||
| Right-of-use assets obtained in exchange for new operating lease liabilities | ||||
| Increase in right-of-use assets and operating lease liabilities from operating lease modifications | ||||
| Supplemental disclosure of non-cash investing and financing activities: | ||||
| Purchases of property and equipment included in accounts payable and accrued expenses | ||||
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