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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|
| Loss before income tax | ||||
| Depreciation and amortization of non-current assets | ||||
| Foreign currency exchange (gain) loss, net | ||||
| Depreciation of right-of-use assets | ||||
| Share-based compensation expense | ||||
| Income tax expense | ||||
| Amortization of premium on investments | ||||
| Receivables and other | ||||
| VAT receivable | ||||
| Prepaid expenses and other assets | ||||
| Trade accounts payable and other | ||||
| Deferred revenue | ||||
| License liabilities | ||||
| Other liabilities | ||||
| Net cash (used in) provided by operating activities | ||||
| Purchases of property and equipment | ||||
| Purchases of investments | ||||
| Maturities of investments | ||||
| Net cash (used in) provided by investing activities | ||||
| Proceeds from option exercises | ||||
| Proceeds from borrowings | ||||
| Payment of principal portion of lease liabilities | ||||
| Net cash (used in) provided by financing activities | ||||
| Net (decrease) increase in cash and cash equivalents | ||||
| Issuance of common shares to VUmc in lieu of payment for license liabilities | ||||
| Interest received, classified as operating activities | ||||
| Interest paid, classified as operating activities | ||||
| Cash flows from operating activities: | ||||
| Net loss | ||||
| Adjustments to reconcile net loss to net cash used in operating activities | ||||
| Depreciation and amortization | ||||
| Non-cash operating lease expense | ||||
| Foreign currency exchange gain loss, net | ||||
| Share-based compensation expense | ||||
| Accrued interest on borrowings | ||||
| Amortization of premium on short-term investments | ||||
| Deferred income taxes | ||||
| Changes in operating assets and liabilities: | ||||
| Prepaid expenses and other current assets | ||||
| Other non-current assets | ||||
| Accounts payable | ||||
| Accrued expenses and other current liabilities | ||||
| Operating lease liabilities | ||||
| License liabilities | ||||
| Net cash used in operating activities | ||||
| Cash flows from investing activities: | ||||
| Purchases of property and equipment | ||||
| Proceeds from sale of property and equipment | ||||
| Purchases of investments | ||||
| Maturities of investments | ||||
| Net cash generated from (used in) investing activities | ||||
| Cash flows from financing activities: | ||||
| Proceeds from option exercises | ||||
| Repayment of borrowings | ||||
| Net cash used in financing activities | ||||
| Net decrease in cash and cash equivalents | ||||
| Cash and cash equivalents at beginning of year | ||||
| Effects of exchange rate changes | ||||
| Cash and cash equivalents at end of year | ||||
| Supplemental disclosure of cash flow information: | ||||
| Cash paid for income taxes | ||||
| Operating right-of-use assets obtained in exchange for operating lease liabilities | ||||
| Adjustment to operating lease right-of-use assets from lease modification | ||||
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