| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| Venture Fund XI, L.P. Atlas | 9,798,075 | 0 | - |
| ADVISORS LLC ORBIMED | 5,779,071 | 0 | - |
| VALUE FUND L P BIOTECHNOLOGY | 1,794,218 | 0 | - |
| Natalie C. Holles | 400,000 | 0 | - |
| Robert Ho | 367,955 | 0 | - |
| Adrian S. Ray | 309,871 | 0 | - |
| Edward R. Conner | 132,000 | 0 | - |
| Christopher Dinsmore | 116,000 | 0 | - |
| Julie Person | 100,000 | 0 | - |
| Dennis Dean | 92,000 | 0 | - |
| Jennifer Dittman | 92,000 | 0 | - |
| GEOFF MCDONOUGH | 60,000 | 0 | - |
| Christopher M. Murphy | 30,000 | 0 | - |
| Thomas P Soloway | 20,000 | 0 | - |
| Hans Martin Seidel | 20,000 | 0 | - |
| David P Bonita | 20,000 | 0 | - |
| Michael Gladstone | 20,000 | 0 | - |
| Mark T Iwicki | 20,000 | 0 | - |
| Shao-Lee Lin | 13,667 | 0 | - |
| ROBERT J PEREZ | 13,667 | 0 | - |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Christopher M. Murphy | Mar 05 |
Grant/Award Acquisition (A)
Compensation/Award
|
30,000 | +30,000 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Christopher M. Murphy | Jan 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
140,000 | +140,000 | $0.00 | +$0 |
| Jennifer Dittman | Jan 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
92,000 | +92,000 | $0.00 | +$0 |
| Julie Person | Jan 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
100,000 | +100,000 | $0.00 | +$0 |
| Dennis Dean | Jan 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
92,000 | +92,000 | $0.00 | +$0 |
| Christopher Dinsmore | Jan 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
116,000 | +116,000 | $0.00 | +$0 |
| Edward R. Conner | Jan 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
132,000 | +132,000 | $0.00 | +$0 |
| Natalie C. Holles | Jan 17 |
Grant/Award Acquisition (A)
Compensation/Award
|
400,000 | +400,000 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Edward R. Conner | Nov 12 |
Open Market Sale (S)
Market Sale
|
0 | -2,117 | $15.00 | -$31,755 |
| Edward R. Conner | Nov 12 |
Option Exercise/Conversion (M)
Compensation/Award
|
2,117 | +2,117 | $4.20 | +$8,891 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Venture Fund XI, L.P. Atlas | Nov 05 |
Other Transaction (J)
Other
|
9,798,075 | -515,688 | $0.00 | -$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| VALUE FUND L P BIOTECHNOLOGY | Oct 31 |
Open Market Sale (S)
Market Sale
|
1,794,218 | -538,420 | $14.30 | -$7,699,406 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Edward R. Conner | Oct 30 |
Open Market Sale (S)
Market Sale
|
0 | -2,673 | $15.00 | -$40,095 |
| Edward R. Conner | Oct 30 |
Option Exercise/Conversion (M)
Compensation/Award
|
2,673 | +2,673 | $4.20 | +$11,226 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Edward R. Conner | Sep 20 |
Open Market Sale (S)
Market Sale
|
0 | -4,790 | $15.00 | -$71,850 |
| Edward R. Conner | Sep 20 |
Option Exercise/Conversion (M)
Compensation/Award
|
4,790 | +4,790 | $4.20 | +$20,118 |
| Julie Person | Sep 20 |
Open Market Sale (S)
Market Sale
|
0 | -9,497 | $14.29 | -$135,684 |
| Julie Person | Sep 20 |
Option Exercise/Conversion (M)
Compensation/Award
|
9,497 | -9,497 | $4.20 | -$39,887 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Julie Person | Sep 20 |
Open Market Sale (S)
Market Sale
|
0 | -503 | $14.00 | -$7,042 |
| Julie Person | Sep 20 |
Option Exercise/Conversion (M)
Compensation/Award
|
503 | +503 | $4.20 | +$2,112 |
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