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FY2020
12 months to Dec 31, 2020
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FY2019
12 months to Dec 31, 2019
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FY2018
12 months to Dec 31, 2018
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FY2017
12 months to Dec 31, 2017
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FY2016
12 months to Dec 31, 2016
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net income | |||||
| Adjustments to reconcile net income to net cash flows from operating activities: | |||||
| Depreciation and amortization | |||||
| Impairment of intangible assets | |||||
| Change in fair value of contingent consideration | |||||
| Payments of contingent consideration | |||||
| Share-based compensation expense | |||||
| Non-cash expense for acquired IPR&D | |||||
| Deferred tax (benefit) expense | |||||
| Unrealized foreign currency (gain) loss | |||||
| Unrealized loss (gain) on forward contracts | |||||
| Unrealized loss (gain) on strategic equity investments | |||||
| Gain on sale of strategic equity investments | |||||
| Gain on sale of asset | |||||
| Gain on modification of purchase option | |||||
| Gain on derecognition of Portola strategic equity investment | |||||
| Inventory obsolescence charge | |||||
| Other | |||||
| Changes in operating assets and liabilities, excluding the effect of acquisitions: | |||||
| Accounts receivable | |||||
| Inventories | |||||
| Prepaid expenses, right of use operating assets and other assets | |||||
| Accounts payable, accrued expenses, lease liabilities and other liabilities | |||||
| Net cash provided by operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of available-for-sale debt securities | |||||
| Proceeds from maturity or sale of available-for-sale debt securities | |||||
| Purchases of mutual funds related to nonqualified deferred compensation plan | |||||
| Proceeds from sale of mutual funds related to nonqualified deferred compensation plan | |||||
| Purchases of property, plant and equipment | |||||
| Payments for acquisitions of businesses, net of cash and restricted cash acquired | |||||
| Purchases of strategic equity investments and options | |||||
| Proceeds from sale of strategic equity investments | |||||
| Purchases of intangible assets | |||||
| Other | |||||
| Net cash (used in) provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from revolving credit facility | |||||
| Payments on revolving credit facility | |||||
| Payments on term loan | |||||
| Repurchase of common stock | |||||
| Net proceeds from issuance of stock under share-based compensation arrangements | |||||
| Payments of contingent consideration | |||||
| Repayment of development-related grants | |||||
| Other | |||||
| Net cash used in financing activities | |||||
| Effect of exchange rate changes on cash and cash equivalents and restricted cash | |||||
| Net change in cash and cash equivalents and restricted cash | |||||
| Cash and cash equivalents and restricted cash at beginning of period | |||||
| Cash and cash equivalents and restricted cash at end of period | |||||
| Supplemental cash flow disclosures: | |||||
| Cash paid for interest (net of amounts capitalized) | |||||
| Cash paid for income taxes | |||||
| Supplemental non-cash disclosures from investing and financing activities: | |||||
| Fair value of strategic investment and purchase option acquired, less upfront cash paid | |||||
| Operating ROU lease assets obtained in exchange for operating lease liabilities | |||||
| Capitalization of construction costs related to facility lease obligations | |||||
| Accounts payable and accrued expenses for purchases of property, plant and equipment and intangible assets | |||||
| Contingent consideration issued in acquisition | |||||
| Fair value of equity shares in Portola settled at closing of the acquisition | |||||
| Fair value of replacement equity awards issued to Portola employees attributable to the pre-combination period | |||||
| Exchange of intellectual property rights for equity shares in Inozyme | |||||
| Cash and cash equivalents | |||||
| Restricted cash included in other current assets | |||||
| Restricted cash included in other noncurrent assets | |||||
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