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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation | |||||
| Stock-based compensation expense | |||||
| Amortization of premiums and accretion of discounts on marketable securities, net | |||||
| Change in fair value of embedded derivatives | |||||
| Amortization of right-of-use asset | |||||
| Non-cash research and development expense | |||||
| Realized gain on marketable securities | |||||
| Noncash interest expense | |||||
| Other noncash expense | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Other long-term assets | |||||
| Accounts payable | |||||
| Accrued clinical trial expenses | |||||
| Accrued expenses and other liabilities | |||||
| Finance lease liability | |||||
| Operating lease liability | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities | |||||
| Purchases of marketable securities | |||||
| Proceeds from maturities and sales of marketable securities | |||||
| Proceeds from sale of property and equipment | |||||
| Purchases of property and equipment | |||||
| Net cash provided by investing activities | |||||
| Cash flows from financing activities | |||||
| Proceeds from issuance of common stock, net of issuance costs | |||||
| Proceeds from Term Loan | |||||
| Proceeds from exercise of stock options | |||||
| Payment for financing lease | |||||
| Payments for financing costs | |||||
| Payments for deferred offering costs | |||||
| Repurchase of common shares to pay employee withholding taxes | |||||
| Net cash (used in) provided by financing activities | |||||
| Net change in cash and cash equivalents and restricted cash | |||||
| Cash and cash equivalents at the beginning of the period | |||||
| Cash and cash equivalents at the end of the period | |||||
| Cash and cash equivalents and restricted cash at the beginning of the period | |||||
| Cash and cash equivalents and restricted cash at the end of the period | |||||
| Supplemental disclosure of cash flow information | |||||
| Cash paid for income taxes | |||||
| Cash paid for interest | |||||
| Right-of-use assets obtained in exchange for finance lease liabilities | |||||
| Right-of-use assets obtained in exchange for operating lease liabilities | |||||
| Issuance of warrant with Term Loan | |||||
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