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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating Activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Depreciation and amortization [note 4] | |||||
| Stock-based compensation [note 10[c], note 10[d], note 10[e]] and note 10[f]] | |||||
| Shares issued as settlement with trade vendor | |||||
| Accrued interest on SVB convertible debt [note 8] | |||||
| Amortization of 2024 SVB convertible term loan transaction costs [note 8] | |||||
| Accretion of discount on modification of debt [note 8] | |||||
| Loss on extinguishment of 2023 SVB convertible term loan [note 8] | |||||
| Change in fair value of contingent consideration [note 4 and note 5] | |||||
| Changes in operating assets and liabilities: | |||||
| Grant receivable | |||||
| Prepaid expenses and other assets | |||||
| Nonrelated Party | |||||
| Adare Pharma Solutions | |||||
| Total prepaid expenses and other assets | |||||
| Accounts payable | |||||
| Nonrelated Party | |||||
| Adare Pharma Solutions | |||||
| Total accounts payable | |||||
| Accrued liabilities other | |||||
| Nonrelated Party | |||||
| Adare Pharma Solutions | |||||
| Total accrued liabilities other | |||||
| Accrued clinical liabilities | |||||
| Accrued compensation | |||||
| Lease obligation | |||||
| Net cash used in operating activities | |||||
| Financing Activities: | |||||
| Proceeds from exercise of warrants [note 10[g]] | |||||
| Proceeds from employee stock purchase plan [note 10[e]] | |||||
| Taxes paid related to net share settlement of equity awards | |||||
| Proceeds from private placement, net of issuance costs [note 10[b]] | |||||
| November 2022 Private Placement | |||||
| May 2023 Private Placement | |||||
| Proceeds from registered direct offering, net of issuance costs | |||||
| Proceeds from June 2025 public offering, net of issuance costs [note 7b] | |||||
| Proceeds from June 2025 public offering exercise of overallotment option, net of issuance costs [note 10b] | |||||
| Repayment of 2023 SVB convertible term loan [note 6 and note 8] | |||||
| Receipt of 2024 SVB convertible term loan less transaction costs [note 6 and note 8] | |||||
| Receipt of 2024 SVB convertible term loan second tranche [note 6 and note 8] | |||||
| Net cash provided by financing activities | |||||
| Investing Activities: | |||||
| Purchase of property and equipment | |||||
| Loss on disposal of property and equipment | |||||
| Realized gain on investments | |||||
| Purchase of investments | |||||
| Maturities of investments | |||||
| Net cash provided by (used in) investing activities | |||||
| Effect of exchange rate changes on cash | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of year | |||||
| Cash, cash equivalents and restricted cash at end of year | |||||
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