2021 Q4 Form 10-K Financial Statement

#000156459022007867 Filed on March 01, 2022

View on sec.gov

Income Statement

Concept 2021 Q4 2021 2020 Q4
Revenue $20.26M $295.7M $31.27M
YoY Change -35.2% 235.34% -9.38%
Cost Of Revenue $881.0K $3.470M $800.0K
YoY Change 10.13% 47.72%
Gross Profit $19.38M $292.2M $30.46M
YoY Change -36.38% 240.47%
Gross Profit Margin 95.65% 98.83% 97.43%
Selling, General & Admin $21.97M $76.36M $20.03M
YoY Change 9.69% 28.98% 62.58%
% of Gross Profit 113.37% 26.13% 65.76%
Research & Development $53.49M $178.6M $35.57M
YoY Change 50.37% 25.24% -3.42%
% of Gross Profit 275.99% 61.13% 116.78%
Depreciation & Amortization $1.655M $4.600M $1.840M
YoY Change -10.05% -9.8% 10.84%
% of Gross Profit 8.54% 1.57% 6.04%
Operating Expenses $75.46M $178.6M $55.60M
YoY Change 35.71% 25.24% 3.38%
Operating Profit -$56.08M $113.6M -$25.14M
YoY Change 123.06% -196.89%
Interest Expense -$14.52M -$77.20M -$12.77M
YoY Change 13.72% 26.4% 7.76%
% of Operating Profit -67.97%
Other Income/Expense, Net $2.992M $5.051M $180.0K
YoY Change 1562.22% -371.85% -35.71%
Pretax Income -$67.61M -$28.72M -$37.73M
YoY Change 79.19% -84.3% 22.3%
Income Tax $0.00
% Of Pretax Income
Net Earnings -$65.51M -$28.72M -$37.73M
YoY Change 73.63% -84.29% 22.3%
Net Earnings / Revenue -323.34% -9.72% -120.68%
Basic Earnings Per Share -$0.11
Diluted Earnings Per Share -$255.3K -$104.5K -$194.9K
COMMON SHARES
Basic Shares Outstanding 228.9K
Diluted Shares Outstanding 228.9K

Balance Sheet

Concept 2021 Q4 2021 2020 Q4
SHORT-TERM ASSETS
Cash & Short-Term Investments $306.9M $306.9M $99.90M
YoY Change 207.23% 207.23% 61.65%
Cash & Equivalents $291.9M $291.9M $99.87M
Short-Term Investments $14.99M $14.99M
Other Short-Term Assets $3.171M $23.53M $2.009M
YoY Change 57.84% 85.3% 97.93%
Inventory
Prepaid Expenses $20.36M $10.75M
Receivables $1.518M $1.518M $1.157M
Other Receivables $0.00 $0.00 $0.00
Total Short-Term Assets $332.0M $332.0M $113.8M
YoY Change 191.76% 191.72% 31.49%
LONG-TERM ASSETS
Property, Plant & Equipment $60.03M $91.08M $26.79M
YoY Change 124.07% 51.05% 1.76%
Goodwill $24.88M $25.45M
YoY Change -2.26% 9.76%
Intangibles $8.488M $10.89M
YoY Change -22.03% 3.64%
Long-Term Investments
YoY Change
Other Assets $9.537M $9.537M $4.123M
YoY Change 131.31% 132.61% 190.97%
Total Long-Term Assets $134.0M $134.0M $100.7M
YoY Change 33.01% 33.05% 46.41%
TOTAL ASSETS
Total Short-Term Assets $332.0M $332.0M $113.8M
Total Long-Term Assets $134.0M $134.0M $100.7M
Total Assets $466.0M $466.0M $214.5M
YoY Change 117.22% 117.23% 38.1%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $30.49M $30.49M $17.02M
YoY Change 79.17% 79.33% 25.44%
Accrued Expenses $42.09M $44.72M $29.06M
YoY Change 44.86% 44.25% -7.26%
Deferred Revenue $12.43M $17.19M
YoY Change -27.7% -41.09%
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due $728.0K $1.063M $833.0K
YoY Change -12.61% -33.56% 28.95%
Total Short-Term Liabilities $156.9M $156.9M $129.9M
YoY Change 20.83% 20.82% 6.28%
LONG-TERM LIABILITIES
Long-Term Debt $12.82M $13.14M $18.88M
YoY Change -32.08% -30.47% 41.1%
Other Long-Term Liabilities $1.577M $248.0M $1.514M
YoY Change 4.16% -0.93% -63.87%
Total Long-Term Liabilities $14.40M $261.1M $20.39M
YoY Change -29.39% -3.01% 16.07%
TOTAL LIABILITIES
Total Short-Term Liabilities $156.9M $156.9M $129.9M
Total Long-Term Liabilities $14.40M $261.1M $20.39M
Total Liabilities $171.3M $431.5M $150.3M
YoY Change 14.02% 10.28% 7.51%
SHAREHOLDERS EQUITY
Retained Earnings -$1.490B -$1.466B
YoY Change 1.63% 14.08%
Common Stock $2.569M $1.961M
YoY Change 31.0% 42.31%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $34.44M $34.44M -$203.7M
YoY Change
Total Liabilities & Shareholders Equity $466.0M $466.0M $214.5M
YoY Change 117.22% 117.23% 38.1%

Cashflow Statement

Concept 2021 Q4 2021 2020 Q4
OPERATING ACTIVITIES
Net Income -$65.51M -$28.72M -$37.73M
YoY Change 73.63% -84.29% 22.3%
Depreciation, Depletion And Amortization $1.655M $4.600M $1.840M
YoY Change -10.05% -9.8% 10.84%
Cash From Operating Activities -$22.93M $10.15M -$35.59M
YoY Change -35.58% -107.29% 11.99%
INVESTING ACTIVITIES
Capital Expenditures -$8.962M $33.81M -$840.0K
YoY Change 966.9% 875.59% -20.75%
Acquisitions
YoY Change
Other Investing Activities -$4.337M -$9.336M $0.00
YoY Change 852.65%
Cash From Investing Activities -$13.30M -$43.15M -$830.0K
YoY Change 1502.29% 871.63% -21.7%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net
YoY Change
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities 71.61M 225.3M 24.65M
YoY Change 190.49% 22.52% 1856.35%
NET CHANGE
Cash From Operating Activities -22.93M 10.15M -35.59M
Cash From Investing Activities -13.30M -43.15M -830.0K
Cash From Financing Activities 71.61M 225.3M 24.65M
Net Change In Cash 35.38M 192.1M -11.77M
YoY Change -400.59% 372.01% -62.73%
FREE CASH FLOW
Cash From Operating Activities -$22.93M $10.15M -$35.59M
Capital Expenditures -$8.962M $33.81M -$840.0K
Free Cash Flow -$13.97M -$23.67M -$34.75M
YoY Change -59.81% -83.4% 13.12%

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CY2020 us-gaap Increase Decrease In Other Operating Capital Net
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CY2019 us-gaap Increase Decrease In Other Operating Capital Net
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CY2019 us-gaap Net Cash Provided By Used In Operating Activities
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CY2020 us-gaap Payments To Acquire Property Plant And Equipment
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CY2020 us-gaap Net Cash Provided By Used In Investing Activities
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CY2019 us-gaap Net Cash Provided By Used In Investing Activities
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CY2019 us-gaap Proceeds From Issuance Or Sale Of Equity
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CY2021 agen Proceeds From Sale Of Subsidiary Shares In Initial Public Offering
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CY2021 agen Proceeds From Employee Stock Purchases And Option Exercises
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CY2019 agen Proceeds From Employee Stock Purchases And Option Exercises
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CY2021 agen Purchase Of Treasury Shares To Satisfy Tax Withholdings
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CY2020 us-gaap Finance Lease Principal Payments
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CY2021 us-gaap Net Cash Provided By Used In Financing Activities
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CY2020 us-gaap Net Cash Provided By Used In Financing Activities
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CY2019 us-gaap Net Cash Provided By Used In Financing Activities
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CY2020 us-gaap Effect Of Exchange Rate On Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
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CY2021 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
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CY2020 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
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CY2019 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
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CY2019Q4 us-gaap Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Including Disposal Group And Discontinued Operations
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CY2019 us-gaap Capital Expenditures Incurred But Not Yet Paid
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CY2020 us-gaap Noncontrolling Interest Increase From Subsidiary Equity Issuance
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CY2020 us-gaap Right Of Use Asset Obtained In Exchange For Operating Lease Liability
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CY2021 agen Number Of Subsidiaries Not Owned
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<p style="margin-top:18pt;margin-bottom:0pt;text-indent:1.7%;font-weight:bold;font-style:italic;font-family:Times New Roman;font-size:10pt;text-transform:none;font-variant: normal;">(c) Use of Estimates</p> <p style="margin-top:6pt;margin-bottom:0pt;text-indent:3.4%;font-family:Times New Roman;font-size:10pt;font-weight:normal;font-style:normal;text-transform:none;font-variant: normal;">The preparation of consolidated financial statements in conformity with U.S. generally accepted accounting principles requires us to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosures of contingent assets and liabilities at the date of the consolidated financial statements and the reported amounts of revenues and expenses during the reporting period. We base those estimates on historical experience and on various assumptions that are believed to be reasonable under the circumstances. Actual results could differ from those estimates.</p>
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CY2019Q4 us-gaap Cash And Cash Equivalents At Carrying Value
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CY2020Q4 us-gaap Deferred Tax Assets Valuation Allowance
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CY2021Q4 us-gaap Deferred Tax Assets Net
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1052000
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CY2021Q4 us-gaap Deferred Income Tax Liabilities
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CY2020Q4 us-gaap Deferred Income Tax Liabilities
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CY2021Q4 us-gaap Deferred Tax Liabilities
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CY2020Q4 us-gaap Deferred Tax Liabilities
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CY2021 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
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CY2019 us-gaap Income Tax Reconciliation Change In Deferred Tax Assets Valuation Allowance
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CY2021 us-gaap Income Tax Reconciliation Tax Contingencies
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CY2021 agen Effective Income Tax Rate Reconciliation Loan Forgiveness
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CY2021 us-gaap Income Tax Reconciliation Tax Contingencies State And Local
IncomeTaxReconciliationTaxContingenciesStateAndLocal
9242000
CY2020 us-gaap Income Tax Reconciliation Tax Contingencies State And Local
IncomeTaxReconciliationTaxContingenciesStateAndLocal
-4675000
CY2019 us-gaap Income Tax Reconciliation Tax Contingencies State And Local
IncomeTaxReconciliationTaxContingenciesStateAndLocal
4144000
CY2021 us-gaap Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
2290000
CY2020 us-gaap Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
1883000
CY2019 us-gaap Income Tax Reconciliation Nondeductible Expense Share Based Compensation Cost
IncomeTaxReconciliationNondeductibleExpenseShareBasedCompensationCost
1367000
CY2021 us-gaap Income Tax Reconciliation Foreign Income Tax Rate Differential
IncomeTaxReconciliationForeignIncomeTaxRateDifferential
-277000
CY2020 us-gaap Income Tax Reconciliation Foreign Income Tax Rate Differential
IncomeTaxReconciliationForeignIncomeTaxRateDifferential
629000
CY2019 us-gaap Income Tax Reconciliation Foreign Income Tax Rate Differential
IncomeTaxReconciliationForeignIncomeTaxRateDifferential
-564000
CY2021 agen Income Tax Reconciliation Income Tax Expense Benefit Change In Fair Value Of Contingent Consideration
IncomeTaxReconciliationIncomeTaxExpenseBenefitChangeInFairValueOfContingentConsideration
2343000
CY2020 agen Income Tax Reconciliation Income Tax Expense Benefit Change In Fair Value Of Contingent Consideration
IncomeTaxReconciliationIncomeTaxExpenseBenefitChangeInFairValueOfContingentConsideration
287000
CY2019 agen Income Tax Reconciliation Income Tax Expense Benefit Change In Fair Value Of Contingent Consideration
IncomeTaxReconciliationIncomeTaxExpenseBenefitChangeInFairValueOfContingentConsideration
1219000
CY2021 us-gaap Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
-2079000
CY2020 us-gaap Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
-3743000
CY2019 us-gaap Income Tax Reconciliation Other Adjustments
IncomeTaxReconciliationOtherAdjustments
9398000
CY2020Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
3614000
CY2019Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
4292000
CY2018Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
4356000
CY2021 agen Unrecognized Tax Benefits Increase Decrease Related To Current Year Positions
UnrecognizedTaxBenefitsIncreaseDecreaseRelatedToCurrentYearPositions
-484000
CY2020 agen Unrecognized Tax Benefits Increase Decrease Related To Current Year Positions
UnrecognizedTaxBenefitsIncreaseDecreaseRelatedToCurrentYearPositions
88000
CY2019 agen Unrecognized Tax Benefits Increase Decrease Related To Current Year Positions
UnrecognizedTaxBenefitsIncreaseDecreaseRelatedToCurrentYearPositions
122000
CY2021 agen Unrecognized Tax Benefits Increases Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsIncreasesDecreasesResultingFromPriorPeriodTaxPositions
18000
CY2020 agen Unrecognized Tax Benefits Increases Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsIncreasesDecreasesResultingFromPriorPeriodTaxPositions
-766000
CY2019 agen Unrecognized Tax Benefits Increases Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsIncreasesDecreasesResultingFromPriorPeriodTaxPositions
-186000
CY2021Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
3148000
CY2020Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
3614000
CY2019Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
4292000
CY2021Q4 us-gaap Accrued Salaries Current
AccruedSalariesCurrent
14206000
CY2020Q4 us-gaap Accrued Salaries Current
AccruedSalariesCurrent
7643000
CY2021Q4 us-gaap Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
6433000
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
32764087
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
3.70
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
9005010
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
3.58
CY2021 us-gaap Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
2502716
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
3.40
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
1837019
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
3.66
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
3.29
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod
868089
CY2021 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice
5.17
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
32764087
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
3.66
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
6309552
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
0.49
CY2020Q4 us-gaap Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
4457000
CY2021Q4 agen Accrued Contract Manufacturing Costs
AccruedContractManufacturingCosts
5824000
CY2020Q4 agen Accrued Contract Manufacturing Costs
AccruedContractManufacturingCosts
6274000
CY2021Q4 agen Accrued Research Services Current
AccruedResearchServicesCurrent
8550000
CY2020Q4 agen Accrued Research Services Current
AccruedResearchServicesCurrent
4649000
CY2021Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
7078000
CY2020Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
6034000
CY2021Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
42091000
CY2020Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
29057000
CY2019Q2 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
240000000
CY2021Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
400000000
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
0.66
CY2019 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
0.64
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
0.008
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
0.008
CY2019 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
0.018
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0
CY2019 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
0
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
28966901
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue
6309552
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableNumber
17509054
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageExercisePrice
3.84
CY2021Q4 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
3832406
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
2.81
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
2.04
CY2019 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
1.77
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
4200000
CY2020 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
1200000
CY2019 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
385000
CY2021Q4 us-gaap Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Stock Options
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedStockOptions
32000000.0
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
886816
CY2020Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
2.14
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
2025701
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
3.28
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod
1826132
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue
3.17
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
68334
CY2021 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
3.79
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
1018051
CY2021Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
2.39
CY2021 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Vested
SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested
5800000
CY2020 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Vested
SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested
621000
CY2019 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Equity Instruments Other Than Options Aggregate Intrinsic Value Vested
SharebasedCompensationArrangementBySharebasedPaymentAwardEquityInstrumentsOtherThanOptionsAggregateIntrinsicValueVested
357000
CY2021 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
19134000
CY2020 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
10121000
CY2019 us-gaap Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
9892000
CY2021Q4 agen Estimate Of Payments For Clinical Trials
EstimateOfPaymentsForClinicalTrials
486800000
CY2020 agen Clinical Trials Expense
ClinicalTrialsExpense
64700000
CY2019 agen Clinical Trials Expense
ClinicalTrialsExpense
87700000
CY2021Q4 agen Cumulative Payments For Clinical Trials
CumulativePaymentsForClinicalTrials
372500000
CY2021 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
295665000
CY2020 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
88170000
CY2019 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
150048000
CY2021 us-gaap Asset Impairment Charges
AssetImpairmentCharges
0
CY2020Q4 us-gaap Contract With Customer Liability
ContractWithCustomerLiability
45284000
CY2021 agen Contract With Customer Liability Additions
ContractWithCustomerLiabilityAdditions
761000
CY2021 us-gaap Contract With Customer Liability Revenue Recognized
ContractWithCustomerLiabilityRevenueRecognized
22420000
CY2021Q4 us-gaap Contract With Customer Liability
ContractWithCustomerLiability
23625000
CY2021Q4 us-gaap Capitalized Contract Cost Net
CapitalizedContractCostNet
0
CY2021 us-gaap Operating Lease Cost
OperatingLeaseCost
8878000
CY2020 us-gaap Operating Lease Cost
OperatingLeaseCost
4698000
CY2019 us-gaap Operating Lease Cost
OperatingLeaseCost
2551000
CY2021 agen Finance Lease Cost
FinanceLeaseCost
407000
CY2020 agen Finance Lease Cost
FinanceLeaseCost
375000
CY2019 agen Finance Lease Cost
FinanceLeaseCost
221000
CY2021 us-gaap Variable Lease Cost
VariableLeaseCost
1826000
CY2020 us-gaap Variable Lease Cost
VariableLeaseCost
1887000
CY2019 us-gaap Variable Lease Cost
VariableLeaseCost
1414000
CY2021 us-gaap Sublease Income
SubleaseIncome
595000
CY2020 us-gaap Sublease Income
SubleaseIncome
578000
CY2019 us-gaap Sublease Income
SubleaseIncome
561000
CY2021 us-gaap Lease Cost
LeaseCost
10516000
CY2020 us-gaap Lease Cost
LeaseCost
6382000
CY2019 us-gaap Lease Cost
LeaseCost
3625000
CY2021 us-gaap Operating Lease Payments
OperatingLeasePayments
2100000
CY2020 us-gaap Operating Lease Payments
OperatingLeasePayments
1600000
CY2019 us-gaap Operating Lease Payments
OperatingLeasePayments
1400000
CY2021 agen Finance Lease Payments
FinanceLeasePayments
900000
CY2020 agen Finance Lease Payments
FinanceLeasePayments
1800000
CY2021Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
31054000
CY2020Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
33480000
CY2021Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
31054000
CY2020Q4 us-gaap Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
33480000
CY2021Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
2627000
CY2020Q4 us-gaap Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
1950000
CY2021Q4 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
42109000
CY2020Q4 us-gaap Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
34065000
CY2021Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
44736000
CY2020Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
36015000
CY2021Q4 us-gaap Finance Lease Right Of Use Asset
FinanceLeaseRightOfUseAsset
2663000
CY2020Q4 us-gaap Finance Lease Right Of Use Asset
FinanceLeaseRightOfUseAsset
2231000
CY2021Q4 us-gaap Finance Lease Right Of Use Asset
FinanceLeaseRightOfUseAsset
2663000
CY2020Q4 us-gaap Finance Lease Right Of Use Asset
FinanceLeaseRightOfUseAsset
2231000
CY2021Q4 us-gaap Finance Lease Liability Current
FinanceLeaseLiabilityCurrent
335000
CY2020Q4 us-gaap Finance Lease Liability Current
FinanceLeaseLiabilityCurrent
746000
CY2021Q4 us-gaap Finance Lease Liability Noncurrent
FinanceLeaseLiabilityNoncurrent
318000
CY2020Q4 us-gaap Finance Lease Liability Noncurrent
FinanceLeaseLiabilityNoncurrent
66000
CY2021Q4 us-gaap Finance Lease Liability
FinanceLeaseLiability
653000
CY2020Q4 us-gaap Finance Lease Liability
FinanceLeaseLiability
812000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
7209000
CY2021Q4 us-gaap Finance Lease Liability Payments Due Next Twelve Months
FinanceLeaseLiabilityPaymentsDueNextTwelveMonths
373000
CY2021Q4 agen Expected Sublease Receipts Payments To Be Received Due Next Twelve Months
ExpectedSubleaseReceiptsPaymentsToBeReceivedDueNextTwelveMonths
613000
CY2021Q4 agen Net Future Lease Commitments Payments Due Next Twelve Months
NetFutureLeaseCommitmentsPaymentsDueNextTwelveMonths
7449000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
9568000
CY2021Q4 us-gaap Finance Lease Liability Payments Due Year Two
FinanceLeaseLiabilityPaymentsDueYearTwo
248000
CY2021Q4 agen Net Future Lease Commitments Payments Due Year Two
NetFutureLeaseCommitmentsPaymentsDueYearTwo
9816000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
8357000
CY2021Q4 us-gaap Finance Lease Liability Payments Due Year Three
FinanceLeaseLiabilityPaymentsDueYearThree
88000
CY2021Q4 agen Net Future Lease Commitments Payments Due Year Three
NetFutureLeaseCommitmentsPaymentsDueYearThree
8445000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
8544000
CY2021Q4 agen Net Future Lease Commitments Payments Due Year Four
NetFutureLeaseCommitmentsPaymentsDueYearFour
8544000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
8219000
CY2021Q4 agen Net Future Lease Commitments Payments Due Year Five
NetFutureLeaseCommitmentsPaymentsDueYearFive
8219000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due After Year Five
LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive
77418000
CY2021Q4 agen Net Future Lease Commitments Payments Due After Year Five
NetFutureLeaseCommitmentsPaymentsDueAfterYearFive
77418000
CY2021Q4 us-gaap Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
104897000
CY2021Q4 us-gaap Finance Lease Liability Payments Due
FinanceLeaseLiabilityPaymentsDue
709000
CY2021Q4 agen Expected Sublease Receipts Payments To Be Received
ExpectedSubleaseReceiptsPaymentsToBeReceived
613000
CY2021Q4 agen Net Future Lease Commitments Payments Due
NetFutureLeaseCommitmentsPaymentsDue
104993000
CY2021Q4 us-gaap Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
60161000
CY2021Q4 us-gaap Finance Lease Liability Undiscounted Excess Amount
FinanceLeaseLiabilityUndiscountedExcessAmount
56000
CY2021Q4 us-gaap Operating Lease Liability
OperatingLeaseLiability
44736000
CY2021Q4 us-gaap Finance Lease Liability
FinanceLeaseLiability
653000
CY2021Q4 agen Expected Lease Incentives To Be Received Due Next Twelve Months
ExpectedLeaseIncentivesToBeReceivedDueNextTwelveMonths
14500000
CY2021Q4 agen Finance Lease Not Yet Commenced Future Lease Payments
FinanceLeaseNotYetCommencedFutureLeasePayments
22400000
CY2021 agen Finance Lease Not Yet Commenced Expected Commencement Year
FinanceLeaseNotYetCommencedExpectedCommencementYear
2022
CY2021Q4 us-gaap Lessee Finance Lease Lease Not Yet Commenced Term Of Contract1
LesseeFinanceLeaseLeaseNotYetCommencedTermOfContract1
P3Y
CY2021Q4 agen Liability Related To Sale Of Future Royalties And Milestones Including Unamortized Transaction Costs
LiabilityRelatedToSaleOfFutureRoyaltiesAndMilestonesIncludingUnamortizedTransactionCosts
254105000
CY2021Q4 agen Liability Related To Sale Of Future Royalties Unamortized Transaction Costs
LiabilityRelatedToSaleOfFutureRoyaltiesUnamortizedTransactionCosts
357000
CY2021Q4 agen Liability Related To Sale Of Future Royalties And Milestones Net
LiabilityRelatedToSaleOfFutureRoyaltiesAndMilestonesNet
253748000
CY2021Q4 us-gaap Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
0.116
CY2021Q4 us-gaap Finance Lease Weighted Average Discount Rate Percent
FinanceLeaseWeightedAverageDiscountRatePercent
0.084
CY2021Q4 us-gaap Other Long Term Debt Current
OtherLongTermDebtCurrent
582000
CY2021Q4 us-gaap Long Term Debt And Capital Lease Obligations Including Current Maturities
LongTermDebtAndCapitalLeaseObligationsIncludingCurrentMaturities
13551000
CY2020Q4 us-gaap Other Long Term Debt Current
OtherLongTermDebtCurrent
687000
CY2020Q4 us-gaap Long Term Debt And Capital Lease Obligations Including Current Maturities
LongTermDebtAndCapitalLeaseObligationsIncludingCurrentMaturities
19712000
CY2021Q4 us-gaap Debt Instrument Carrying Amount
DebtInstrumentCarryingAmount
13800000
CY2020Q4 us-gaap Debt Instrument Carrying Amount
DebtInstrumentCarryingAmount
20000000.0
CY2020Q1 us-gaap Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights
ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights
675000
CY2020Q1 us-gaap Warrants And Rights Outstanding Term
WarrantsAndRightsOutstandingTerm
P5Y
CY2020Q1 us-gaap Class Of Warrant Or Right Exercise Price Of Warrants Or Rights1
ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1
4.48
CY2020Q1 agen Price Per Share Premium To Average Closing Price Percentage
PricePerSharePremiumToAverageClosingPricePercentage
0.20
CY2020Q4 agen Liability Related To Sale Of Future Royalties And Milestones Including Unamortized Transaction Costs
LiabilityRelatedToSaleOfFutureRoyaltiesAndMilestonesIncludingUnamortizedTransactionCosts
234041000
CY2021 agen Non Cash Royalty And Milestone Revenue Recognized
NonCashRoyaltyAndMilestoneRevenueRecognized
44355000
CY2021 agen Non Cash Interest Expense Related To Sale Of Future Royalties
NonCashInterestExpenseRelatedToSaleOfFutureRoyalties
64419000
CY2021Q4 agen Contingent Consideration Liability Fair Value Disclosure
ContingentConsiderationLiabilityFairValueDisclosure
1689000
CY2021 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
295665000
CY2020 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
88170000
CY2021Q4 us-gaap Nonfinancial Liabilities Fair Value Disclosure
NonfinancialLiabilitiesFairValueDisclosure
1689000
CY2019 us-gaap Revenue From Contract With Customer Excluding Assessed Tax
RevenueFromContractWithCustomerExcludingAssessedTax
150048000
CY2020Q4 agen Contingent Consideration Liability Fair Value Disclosure
ContingentConsiderationLiabilityFairValueDisclosure
10208000
CY2020Q4 us-gaap Nonfinancial Liabilities Fair Value Disclosure
NonfinancialLiabilitiesFairValueDisclosure
10208000
CY2021Q4 us-gaap Fair Value Assets Level1 To Level2 Transfers Amount
FairValueAssetsLevel1ToLevel2TransfersAmount
0
CY2021Q4 us-gaap Debt Instrument Carrying Amount
DebtInstrumentCarryingAmount
13800000
CY2020Q4 us-gaap Debt Instrument Carrying Amount
DebtInstrumentCarryingAmount
20000000.0
CY2021 us-gaap Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
1100000
CY2020 us-gaap Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
1100000
CY2019 us-gaap Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
922000
CY2021 us-gaap Defined Contribution Plan Cost Recognized
DefinedContributionPlanCostRecognized
1100000
CY2020 us-gaap Defined Contribution Plan Cost Recognized
DefinedContributionPlanCostRecognized
1100000
CY2019 us-gaap Defined Contribution Plan Cost Recognized
DefinedContributionPlanCostRecognized
922000
CY2021Q4 us-gaap Noncurrent Assets
NoncurrentAssets
69566000
CY2020Q4 us-gaap Noncurrent Assets
NoncurrentAssets
30913000
CY2021 dei Auditor Firm
AuditorFirmId
185

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