| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| Venture Management Co. VI, L.L.C. Polaris | 12,853,817 | 0 | - |
| TERRANCE MCGUIRE | 10,853,817 | 0 | - |
| Venture Partners VI, L.P. Polaris | 9,853,817 | 0 | - |
| CAPITAL LLC ORBIMED | 9,272,225 | 0 | - |
| Capital GP IV LLC OrbiMed | 6,020,366 | 0 | - |
| ADVISORS LLC ORBIMED | 5,955,674 | 0 | - |
| Tillman U. Gerngross | 2,644,319 | 0 | - |
| Arnon Rosenthal | 2,454,422 | +189,765 | 1.8 |
| Robert King | 550,871 | 0 | - |
| Sara Kenkare-Mitra | 501,652 | -10,600 | 0.84 |
| VI (AIV) Feeder Corp. Holding Partnership, L.P. PVP | 500,000 | 0 | - |
| Neil Lindsay Berkley | 399,260 | +54,848 | 1.66 |
| Gary Romano | 332,977 | 0 | - |
| MARC GRASSO | 296,072 | 0 | - |
| Robert Paul | 234,619 | 0 | - |
| SHEHNAAZ SULIMAN | 177,598 | 0 | - |
| David M. Wehner | 115,330 | 0 | - |
| Sabah Oney | 109,689 | 0 | - |
| Grace Wong-Sarad | 104,645 | -4,713 | 0.87 |
| LOUIS J JR LAVIGNE | 99,409 | +28,700 | ∞ |
| Kristine Yaffe | 95,409 | +27,700 | 28.7 |
| RICHARD H SCHELLER | 95,366 | +28,700 | ∞ |
| ELIZABETH A. GAROFALO | 89,950 | +28,700 | ∞ |
| Calvin Yu | 76,686 | 0 | - |
| Paula Hammond | 74,909 | +14,700 | 2.05 |
| ERROL B DESOUZA | 69,950 | +28,700 | ∞ |
| Mark Altmeyer | 69,950 | +28,700 | ∞ |
| CARL L GORDON | 20,000 | 0 | - |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Grace Wong-Sarad | Apr 17 |
Open Market Sale (S)
Market Sale
|
104,645 | -1,820 | $2.65 | -$4,823 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Neil Lindsay Berkley | Mar 13 |
Grant/Award Acquisition (A)
Compensation/Award
|
399,260 | +54,600 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Arnon Rosenthal | Mar 13 |
Grant/Award Acquisition (A)
Compensation/Award
|
2,454,422 | +116,246 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Grace Wong-Sarad | Mar 12 |
Open Market Sale (S)
Market Sale
|
106,465 | -1,000 | $2.65 | -$2,650 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Grace Wong-Sarad | Mar 03 |
Open Market Sale (S)
Market Sale
|
107,465 | -3,367 | $2.08 | -$7,012 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Grace Wong-Sarad | Mar 03 |
Open Market Sale (S)
Market Sale
|
110,832 | -8,071 | $2.12 | -$17,137 |
| Arnon Rosenthal | Mar 03 |
Open Market Sale (S)
Market Sale
|
2,338,176 | -81,864 | $2.12 | -$173,821 |
| Neil Lindsay Berkley | Mar 03 |
Open Market Sale (S)
Market Sale
|
344,660 | -29,649 | $2.12 | -$62,953 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Grace Wong-Sarad | Feb 26 |
Open Market Sale (S)
Market Sale
|
118,903 | -4,079 | $2.50 | -$10,197 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Grace Wong-Sarad | Dec 08 |
Open Market Sale (S)
Market Sale
|
122,982 | -4,753 | $1.21 | -$5,751 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Sara Kenkare-Mitra | Dec 03 |
Open Market Sale (S)
Market Sale
|
501,652 | -41,687 | $1.12 | -$46,672 |
| Neil Lindsay Berkley | Dec 03 |
Open Market Sale (S)
Market Sale
|
374,309 | -37,261 | $1.12 | -$41,717 |
| Grace Wong-Sarad | Dec 03 |
Open Market Sale (S)
Market Sale
|
127,735 | -8,056 | $1.12 | -$9,018 |
| Arnon Rosenthal | Dec 03 |
Open Market Sale (S)
Market Sale
|
2,420,040 | -104,347 | $1.12 | -$116,826 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Arnon Rosenthal | Nov 12 |
Grant/Award Acquisition (A)
Compensation/Award
|
2,524,387 | +174,167 | $0.00 | +$0 |
| Neil Lindsay Berkley | Nov 12 |
Grant/Award Acquisition (A)
Compensation/Award
|
411,570 | +65,000 | $0.00 | +$0 |
| Grace Wong-Sarad | Nov 12 |
Grant/Award Acquisition (A)
Compensation/Award
|
135,791 | +32,343 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Grace Wong-Sarad | Sep 04 |
Open Market Sale (S)
Market Sale
|
103,448 | -5,910 | $2.50 | -$14,756 |
| Neil Lindsay Berkley | Sep 04 |
Open Market Sale (S)
Market Sale
|
346,570 | -15,842 | $2.50 | -$39,554 |
| Sara Kenkare-Mitra | Sep 04 |
Open Market Sale (S)
Market Sale
|
543,339 | -23,638 | $2.50 | -$59,019 |
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