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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| CASH FLOWS FROM OPERATING ACTIVITIES: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash provided by (used in) operating activities: | |||||
| Depreciation and amortization | |||||
| Stock-based compensation | |||||
| Accretion/amortization of investments, net | |||||
| Amortization of right-of-use assets – operating | |||||
| Non-cash interest expense for the sale of future royalties | |||||
| Changes in operating assets and liabilities: | |||||
| Receivables from collaborative partners | |||||
| Prepaid expenses and other assets | |||||
| Accounts payable and other liabilities | |||||
| Operating lease liabilities | |||||
| Net cash provided by (used in) operating activities | |||||
| CASH FLOWS FROM INVESTING ACTIVITIES: | |||||
| Purchase of investments | |||||
| Sales and maturities of investments | |||||
| Proceeds from the sale of property and equipment | |||||
| Purchases of property and equipment | |||||
| Net cash provided by investing activities | |||||
| CASH FLOWS FROM FINANCING ACTIVITIES: | |||||
| Proceeds from public offerings, net of underwriters' fees | |||||
| Proceeds from issuance of common stock | |||||
| Proceeds from the sale of future royalties | |||||
| Principal repayment of liability for sale of future royalties | |||||
| Payments for repurchase of common stock | |||||
| Payment for net share settlement of equity awards | |||||
| Payments for offering costs, net | |||||
| Payments for issuance costs related to the sale of future royalties | |||||
| Net cash (used in) provided by financing activities | |||||
| Net increase (decrease) in cash and cash equivalents | |||||
| Cash and cash equivalents, beginning of period | |||||
| Cash and cash equivalents, end of period | |||||
| SUPPLEMENTAL DISCLOSURE OF CASH FLOW INFORMATION | |||||
| Interest portion of repayment for sale of future royalties | |||||
| Non-cash investing and financing activities: | |||||
| Leased assets obtained in exchange for operating lease liabilities | |||||
| State income taxes paid | |||||
| Amounts accrued for property and equipment | |||||
| Amounts accrued for issuance costs related to the sale of future royalties | |||||
| Amounts accrued for repurchase of common stock | |||||
| Receivable related to issuance of common stock, upon exercise of stock options | |||||
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