| Insider Name | Current Shares | Net Change (1yr) | Buy/Sell Ratio |
|---|---|---|---|
| Life Sciences VIII, L.P. Frazier | 10,542,790 | 0 | - |
| James N Topper | 8,764,232 | 0 | - |
| JONATHAN SILVERSTEIN | 4,267,564 | 0 | - |
| Capital Life Sciences Investors, LLC Bain | 3,979,292 | 0 | - |
| ADVISORS LLC ORBIMED | 3,534,537 | 0 | - |
| Todd Franklin Watanabe | 914,113 | 0 | - |
| BHASKAR CHAUDHURI | 867,826 | 0 | - |
| Todd Watanabe | 720,755 | -116,179 | 0.47 |
| DAVID W OSBORNE | 268,854 | 0 | - |
| David Joseph Topper | 182,774 | 0 | - |
| Larry Todd Edwards | 175,281 | -8,974 | 0.77 |
| Matthew Richard Moore | 145,505 | 0 | - |
| Masaru Matsuda | 127,573 | -40,504 | 0.48 |
| Patrick Burnett | 120,244 | -10,640 | 0.86 |
| Latha Vairavan | 85,978 | +20,955 | 4.47 |
| Kenneth A. Lock | 63,429 | 0 | - |
| Patricia A. Turney | 62,862 | 0 | - |
| Scott L Burrows | 59,115 | 0 | - |
| Howard G. Welgus | 38,378 | -61,366 | 0.34 |
| SUE-JEAN LIN | 32,513 | -1,442 | 0.94 |
| Patrick J Heron | 32,213 | +5,778 | ∞ |
| Neha Krishnamohan | 27,901 | -6,442 | 0.84 |
| Keith R Leonard | 27,901 | -10,754 | 0.84 |
| Halley E Gilbert | 27,901 | +1,466 | 1.09 |
| DANIEL ESTES | 24,000 | 0 | - |
| Terrie Curran | 23,526 | +5,778 | ∞ |
| Ricky Sun | 13,391 | 0 | - |
| Amit Munshi | 9,799 | +7,799 | ∞ |
| JOSEPH L TURNER | 4,312 | 0 | - |
| John W Smither | 2,793 | 0 | - |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Patrick J Heron | Jun 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
32,213 | +5,778 | $0.00 | +$0 |
| Keith R Leonard | Jun 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
27,901 | +5,778 | $0.00 | +$0 |
| Halley E Gilbert | Jun 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
27,901 | +5,778 | $0.00 | +$0 |
| Amit Munshi | Jun 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
9,799 | +5,778 | $0.00 | +$0 |
| Terrie Curran | Jun 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
23,526 | +5,778 | $0.00 | +$0 |
| Neha Krishnamohan | Jun 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
27,901 | +5,778 | $0.00 | +$0 |
| Howard G. Welgus | Jun 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
38,378 | +5,778 | $0.00 | +$0 |
| SUE-JEAN LIN | Jun 09 |
Grant/Award Acquisition (A)
Compensation/Award
|
32,513 | +5,778 | $0.00 | +$0 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Patrick Burnett | May 13 |
Open Market Sale (S)
Market Sale
|
120,244 | -222 | $21.05 | -$4,673 |
| Latha Vairavan | May 13 |
Open Market Sale (S)
Market Sale
|
85,978 | -435 | $21.05 | -$9,156 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Latha Vairavan | May 06 |
Open Market Sale (S)
Market Sale
|
86,413 | -1,341 | $23.61 | -$31,661 |
| Patrick Burnett | May 06 |
Open Market Sale (S)
Market Sale
|
120,466 | -684 | $23.61 | -$16,149 |
| Masaru Matsuda | May 06 |
Open Market Sale (S)
Market Sale
|
127,573 | -7,372 | $23.27 | -$171,543 |
| Todd Watanabe | May 06 |
Open Market Sale (S)
Market Sale
|
720,755 | -3,172 | $23.61 | -$74,892 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Howard G. Welgus | May 05 |
Open Market Sale (S)
Market Sale
|
32,600 | -7,144 | $22.99 | -$164,219 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Howard G. Welgus | Apr 03 |
Open Market Sale (S)
Market Sale
|
39,744 | -10,000 | $23.88 | -$238,801 |
| Insider | Filing Date | Transaction | Shares | Change | Price | Value |
|---|---|---|---|---|---|---|
| Latha Vairavan | Mar 03 |
Open Market Sale (S)
Market Sale
|
87,835 | -2,772 | $25.16 | -$69,744 |
| Masaru Matsuda | Mar 03 |
Open Market Sale (S)
Market Sale
|
137,125 | -6,553 | $25.16 | -$164,876 |
| Todd Watanabe | Mar 03 |
Open Market Sale (S)
Market Sale
|
787,025 | -36,281 | $25.16 | -$912,851 |
| Larry Todd Edwards | Mar 03 |
Open Market Sale (S)
Market Sale
|
175,281 | -3,584 | $25.16 | -$90,177 |
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