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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Share-based compensation expense | |||||
| Depreciation and amortization | |||||
| Non-cash interest | |||||
| Loss on extinguishment of debt | |||||
| Gain on extinguishment of research and development funding liability | |||||
| Deferred income tax (benefit) provision | |||||
| Other non-cash charges | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable | |||||
| Research and development incentives receivable | |||||
| Prepaid expenses and other assets | |||||
| Operating lease rightofuse assets | |||||
| Accounts payable | |||||
| Accrued expenses and other current liabilities | |||||
| Operating lease liabilities | |||||
| Deferred revenue | |||||
| Other long-term liabilities | |||||
| Net cash used in operating activities | |||||
| Cash used in investing activities: | |||||
| Purchases of property and equipment | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from the issuance of ADSs and non-voting ordinary shares, net of issuance costs | |||||
| Proceeds from the exercise of share options and settlement of restricted share units | |||||
| Principal payments on finance lease obligations | |||||
| Net cash (used in) provided by financing activities | |||||
| Effect of exchange rate changes on cash, cash equivalents and restricted cash | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of period | |||||
| Cash, cash equivalents and restricted cash at end of period | |||||
| Supplemental disclosure of cash flow information | |||||
| Cash paid for interest on debt | |||||
| Cash paid for interest on finance lease obligations | |||||
| Cash (received from) paid for income taxes | |||||
| Cash paid for amounts included in the measurement of operating lease liabilities | |||||
| Changes in purchases of property and equipment in accounts payable and accrued expenses | |||||
| Non-cash impact to operating lease right-of-use assets and operating lease liabilities | |||||
| Property and equipment obtained under finance leases | |||||
| Reconciliation of cash, cash equivalents and restricted cash | |||||
| Cash and cash equivalents | |||||
| Restricted cash included in prepaid expenses and other current assets | |||||
| Restricted cash included in other assets | |||||
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