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FY2025
12 months to Dec 31, 2025
|
FY2024
12 months to Dec 31, 2024
|
FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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|---|---|---|---|---|
| Cash flows from operating activities: | ||||
| Net loss | ||||
| Adjustments to reconcile net loss to net cash used in operating activities: | ||||
| Non-cash share-based compensation | ||||
| Impairment of Artizan preferred stock | ||||
| Acquisition of IPR&D asset | ||||
| Depreciation and amortization | ||||
| Issuance of common shares as payment for license agreement | ||||
| Gain from equity method investment | ||||
| Change in fair value of notes payable | ||||
| Obligation to issue common shares as payment for license agreements and other arrangements | ||||
| Fair value of forward contract and derivative liabilities under license agreement | ||||
| Change in fair value of forward contract and derivative liabilities | ||||
| Issuance of warrant under license agreement | ||||
| Other non-cash items | ||||
| Changes in operating assets and liabilities: | ||||
| Prepaid expenses, income tax receivable, and other current and non-current assets | ||||
| Accounts payable | ||||
| Accrued expenses and other current and non-current liabilities | ||||
| Net cash used in operating activities | ||||
| Cash flows from investing activities: | ||||
| Proceeds from maturities of marketable securities | ||||
| Proceeds from sales of marketable securities | ||||
| Purchases of marketable securities | ||||
| Purchases of property and equipment | ||||
| Payment for IPR&D asset acquisition | ||||
| Cash acquired from acquisition of IPR&D asset | ||||
| Purchase of Artizan preferred stock | ||||
| Other investing activities | ||||
| Net cash provided by (used in) investing activities | ||||
| Cash flows from financing activities: | ||||
| Net transfers from Former Parent | ||||
| Change in restricted cash due to Former Parent | ||||
| Proceeds from issuance of notes payable | ||||
| Proceeds from issuance of common shares | ||||
| Payments of issuance costs | ||||
| Proceeds from issuance of common shares under 2022 Equity Incentive Plan and 2022 Employee Share Purchase Plan | ||||
| Other financing activities | ||||
| Net cash provided by financing activities | ||||
| Effect of exchange rates on cash, cash equivalents and restricted cash | ||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | ||||
| Cash, cash equivalents and restricted cash at beginning of period | ||||
| Cash, cash equivalents and restricted cash at end of period | ||||
| Supplemental disclosure of cash flow information: | ||||
| Cash paid for interest | ||||
| Cash (received) paid for income taxes | ||||
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