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About Cabaletta Bio, Inc.
Cabaletta Bio, Inc. operates as a clinical-stage biotechnology company, which engages in the discovery and development of engineered T cell therapies for B cell-mediated autoimmune diseases. The company is headquartered in Philadelphia, Pennsylvania and currently employs 154 full-time employees. The company went IPO on 2019-10-25. The firm is focused on the discovery and development of engineered T cell therapies that have the potential to provide deep and durable, perhaps curative, responses with one-time administration for patients with autoimmune diseases. Its Cabaletta Approach to B cell Ablation (CABA) platform encompasses two strategies: Chimeric Antigen Receptor T cells for Autoimmunity (CARTA) and Chimeric AutoAntibody Receptor T cells (CAART). CABA-201, its lead product candidate from its CARTA platform, is a 4-1BB co-stimulatory domain-containing fully human CD19-CAR T construct designed to treat patients with a range of autoimmune diseases. Its DSG3-CAART product candidate is being evaluated for the treatment of mPV, a subtype of PV that affects the epithelium of the mucous membranes, in the Phase 1 DesCAARTes TM trial. Its MuSK-CAART product candidate is designed to treat a subset of patients with MG, targeting autoreactive B cells.
Industry: Biological Products, (No Diagnostic Substances) Peers: Theriva Biologics, Inc. Aptevo Therapeutics Inc. bioAffinity Technologies, Inc. Vyant Bio, Inc. Cyclacel Pharmaceuticals, Inc. HUMANIGEN, INC YIELD10 BIOSCIENCE, INC. NexImmune, Inc. Sigilon Therapeutics, Inc.
