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$CALC

$0.85 +$0.00 (0.11%)

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Insider Transactions

Insider Transaction Summary

ADVISORS LLC ORBIMED

4,163,347 shares

Net: 0 B/S: -

James E Flynn

1,422,406 shares

Net: 0 B/S: -

Lifesciences III, L.P. Clarus

1,285,327 shares

Net: 0 B/S: -

Hansoo Michael Keyoung

1,133,596 shares

Net: 0 B/S: -

Venture Partners VI Co Investment Fund LP Sanderling

814,300 shares

Net: 0 B/S: -

ROBERT N WILSON

422,029 shares

Net: +14,500 B/S: ∞

Investments SPV IV LLC Valence

356,989 shares

Net: 0 B/S: -

Eric W Roberts

84,150 shares

Net: +158,677 B/S: ∞

Sudarshan Hebbar

61,539 shares

Net: +98,839 B/S: ∞

Michael J. Dunn

47,125 shares

Net: +47,125 B/S: ∞

ROBERT S BREUIL

35,326 shares

Net: 0 B/S: -

Daniel Salain

35,000 shares

Net: 0 B/S: -

Parisa Zamiri

28,982 shares

Net: 0 B/S: -

Kenneth A. Stauderman

12,944 shares

Net: +48,125 B/S: 49.13

Gerald D. Cagle

12,500 shares

Net: 0 B/S: -

Allan Shaw

10,000 shares

Net: +10,000 B/S: ∞

Daniel E. Geffken

10,000 shares

Net: 0 B/S: -

ERIC BJERKHOLT

10,000 shares

Net: 0 B/S: -

Frederic Guerard

10,000 shares

Net: +10,000 B/S: ∞

FRED A MIDDLETON

10,000 shares

Net: +10,000 B/S: ∞

A. Rachel Leheny

3,500 shares

Net: +81,125 B/S: ∞

Stephen Bardin

3,000 shares

Net: +22,000 B/S: ∞

JULIA MARIE EASTLAND

1,429 shares

Net: 0 B/S: -

CHRISTY L SHAFFER

1,429 shares

Net: 0 B/S: -

CHRISTINA ACKERMANN

1,429 shares

Net: 0 B/S: -

Dirk Sauer

1,429 shares

Net: 0 B/S: -

Alan Glicklich

937 shares

Net: +10,937 B/S: ∞

Insider Name	Current Shares	Net Change (1yr)	Buy/Sell Ratio
ADVISORS LLC ORBIMED	4,163,347	0	-
James E Flynn	1,422,406	0	-
Lifesciences III, L.P. Clarus	1,285,327	0	-
Hansoo Michael Keyoung	1,133,596	0	-
Venture Partners VI Co Investment Fund LP Sanderling	814,300	0	-
ROBERT N WILSON	422,029	+14,500	∞
Investments SPV IV LLC Valence	356,989	0	-
Eric W Roberts	84,150	+158,677	∞
Sudarshan Hebbar	61,539	+98,839	∞
Michael J. Dunn	47,125	+47,125	∞
ROBERT S BREUIL	35,326	0	-
Daniel Salain	35,000	0	-
Parisa Zamiri	28,982	0	-
Kenneth A. Stauderman	12,944	+48,125	49.13
Gerald D. Cagle	12,500	0	-
Allan Shaw	10,000	+10,000	∞
Daniel E. Geffken	10,000	0	-
ERIC BJERKHOLT	10,000	0	-
Frederic Guerard	10,000	+10,000	∞
FRED A MIDDLETON	10,000	+10,000	∞
A. Rachel Leheny	3,500	+81,125	∞
Stephen Bardin	3,000	+22,000	∞
JULIA MARIE EASTLAND	1,429	0	-
CHRISTY L SHAFFER	1,429	0	-
CHRISTINA ACKERMANN	1,429	0	-
Dirk Sauer	1,429	0	-
Alan Glicklich	937	+10,937	∞

Individual Transactions

October 13, 2025

Alan Glicklich

Grant/Award Acquisition

Change: +937

Price: $0.00

Shares: 937

Value: +$0

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Alan Glicklich	Oct 14	Grant/Award Acquisition (A) Compensation/Award	937	+937	$0.00	+$0

September 18, 2025

Eric W Roberts

Open Market Purchase

Change: +2,500

Price: $3.07

Shares: 84,150

Value: +$7,675

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Sep 22	Open Market Purchase (P) Market Purchase	84,150	+2,500	$3.07	+$7,675

September 15, 2025

Eric W Roberts

Open Market Purchase

Change: +3,400

Price: $2.68

Shares: 81,650

Value: +$9,104

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Sep 17	Open Market Purchase (P) Market Purchase	81,650	+3,400	$2.68	+$9,104

September 12, 2025

Eric W Roberts

Open Market Purchase

Change: +5,000

Price: $3.12

Shares: 78,250

Value: +$15,600

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Sep 15	Open Market Purchase (P) Market Purchase	78,250	+5,000	$3.12	+$15,600

September 09, 2025

Eric W Roberts

Open Market Purchase

Change: +2,343

Price: $3.15

Shares: 73,250

Value: +$7,377

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Sep 11	Open Market Purchase (P) Market Purchase	73,250	+2,343	$3.15	+$7,377

August 29, 2025

Eric W Roberts

Open Market Purchase

Change: +800

Price: $2.74

Shares: 70,907

Value: +$2,192

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Sep 02	Open Market Purchase (P) Market Purchase	70,907	+800	$2.74	+$2,192

August 28, 2025

Eric W Roberts

Open Market Purchase

Change: +9,200

Price: $2.86

Shares: 70,107

Value: +$26,339

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Sep 02	Open Market Purchase (P) Market Purchase	70,107	+9,200	$2.86	+$26,339

August 21, 2025

Eric W Roberts

Open Market Purchase

Change: +3,508

Price: $2.79

Shares: 60,907

Value: +$9,797

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Aug 25	Open Market Purchase (P) Market Purchase	60,907	+3,508	$2.79	+$9,797

August 20, 2025

Eric W Roberts

Option Exercise/Conversion

Change: +15,000

Price: $1.53

Shares: 179,706

Value: +$22,950

Eric W Roberts

Open Market Purchase

Change: +2,000

Price: $2.72

Shares: 57,399

Value: +$5,440

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Aug 21	Option Exercise/Conversion (M) Compensation/Award	179,706	+15,000	$1.53	+$22,950
Eric W Roberts	Aug 21	Open Market Purchase (P) Market Purchase	57,399	+2,000	$2.72	+$5,440

August 19, 2025

Eric W Roberts

Open Market Purchase

Change: +1,000

Price: $2.79

Shares: 55,399

Value: +$2,790

Sudarshan Hebbar

Open Market Purchase

Change: +9,563

Price: $2.82

Shares: 61,539

Value: +$26,961

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Aug 21	Open Market Purchase (P) Market Purchase	55,399	+1,000	$2.79	+$2,790
Sudarshan Hebbar	Aug 21	Open Market Purchase (P) Market Purchase	61,539	+9,563	$2.82	+$26,961

August 15, 2025

Eric W Roberts

Open Market Purchase

Change: +5,076

Price: $2.90

Shares: 54,399

Value: +$14,708

Sudarshan Hebbar

Open Market Purchase

Change: +4,392

Price: $2.79

Shares: 51,976

Value: +$12,266

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Aug 19	Open Market Purchase (P) Market Purchase	54,399	+5,076	$2.90	+$14,708
Sudarshan Hebbar	Aug 18	Open Market Purchase (P) Market Purchase	51,976	+4,392	$2.79	+$12,266

August 14, 2025

Sudarshan Hebbar

Open Market Purchase

Change: +1,584

Price: $2.59

Shares: 47,584

Value: +$4,094

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Sudarshan Hebbar	Aug 18	Open Market Purchase (P) Market Purchase	47,584	+1,584	$2.59	+$4,094

July 28, 2025

Kenneth A. Stauderman

Open Market Purchase

Change: +1,000

Price: $3.96

Shares: 12,944

Value: +$3,960

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Kenneth A. Stauderman	Jul 29	Open Market Purchase (P) Market Purchase	12,944	+1,000	$3.96	+$3,960

July 25, 2025

Kenneth A. Stauderman

Open Market Sale

Change: -1,000

Price: $3.65

Shares: 0

Value: -$3,650

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Kenneth A. Stauderman	Jul 29	Open Market Sale (S) Market Sale	0	-1,000	$3.65	-$3,650

July 22, 2025

Eric W Roberts

Open Market Purchase

Change: +1,500

Price: $3.78

Shares: 49,323

Value: +$5,662

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Jul 23	Open Market Purchase (P) Market Purchase	49,323	+1,500	$3.78	+$5,662

July 21, 2025

Eric W Roberts

Open Market Purchase

Change: +1,500

Price: $3.37

Shares: 47,823

Value: +$5,055

A. Rachel Leheny

Open Market Purchase

Change: +1,000

Price: $3.40

Shares: 3,500

Value: +$3,400

Insider	Filing Date	Transaction	Shares	Change	Price	Value
Eric W Roberts	Jul 22	Open Market Purchase (P) Market Purchase	47,823	+1,500	$3.37	+$5,055
A. Rachel Leheny	Jul 21	Open Market Purchase (P) Market Purchase	3,500	+1,000	$3.40	+$3,400