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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash and cash equivalents used in operations: | |||||
| Depreciation | |||||
| Stock-based compensation | |||||
| Amortization of debt issuance costs and discount | |||||
| Payment-in-kind interest | |||||
| Non-cash operating lease, net | |||||
| Non-cash operating lease expense | |||||
| Change in accrued interest income | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid clinical trial costs | |||||
| Other current and non-current assets | |||||
| Accounts payable | |||||
| Accrued expenses | |||||
| Accrued clinical trial costs | |||||
| Other accrued expenses | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Proceeds from maturities of investments | |||||
| Purchases of investments | |||||
| Purchases of property and equipment | |||||
| Net cash used in investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from employee stock purchases | |||||
| Proceeds from exercise of common stock options | |||||
| Proceeds from exercise of common stock warrants | |||||
| Proceeds from convertible debt, net of debt issuance costs of $6,246 and $0 during the years ended December 31, 2025 and 2024, respectively | |||||
| Proceeds from note payable, net of debt issuance costs of $2,255 and $2,438 during the years ended December 31, 2025 and 2024, respectively | |||||
| Proceeds from an ATM offering, net of commission fees and offering costs | |||||
| Proceeds from equity offering, net of underwriting discounts and offering costs | |||||
| Proceeds from an ATM offering, net of issuance costs | |||||
| Proceeds from pre-funded warrants, net of offering costs | |||||
| Payments for secondary registration statement costs | |||||
| Payments for debt issuance costs | |||||
| Payments for finance leases | |||||
| Net cash provided by financing activities | |||||
| Net change in cash and cash equivalents | |||||
| Cash and cash equivalents: | |||||
| Beginning of period | |||||
| End of period | |||||
| Supplemental disclosure of cash flow information: | |||||
| Cash paid for interest | |||||
| Cash paid for operating leases | |||||
| Supplemental disclosures of non-cash investing and financing activities: | |||||
| Common stock warrants issued with the note payable transaction | |||||
| Property and equipment included in accounts payable | |||||
| Deferred financing, offering and registration statement costs included in accounts payable | |||||
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