2021 Q4 Form 10-K Financial Statement
#000110820522000002 Filed on February 24, 2022
Income Statement
Concept | 2021 Q4 | 2021 | 2020 Q4 |
---|---|---|---|
Revenue | $3.135M | $10.65M | $3.024M |
YoY Change | 3.67% | -1.72% | -8.0% |
Cost Of Revenue | $157.0K | $533.0K | $150.0K |
YoY Change | 4.67% | 0.57% | -6.25% |
Gross Profit | $2.978M | $10.12M | $2.870M |
YoY Change | 3.76% | -1.79% | -8.31% |
Gross Profit Margin | 94.99% | 94.99% | 94.91% |
Selling, General & Admin | $4.773M | $17.30M | $3.540M |
YoY Change | 34.83% | 42.6% | 18.0% |
% of Gross Profit | 160.28% | 170.99% | 123.34% |
Research & Development | $10.77M | $34.88M | $5.610M |
YoY Change | 92.01% | 51.22% | -24.8% |
% of Gross Profit | 361.72% | 344.84% | 195.47% |
Depreciation & Amortization | $38.00K | $158.0K | $20.00K |
YoY Change | 90.0% | 12.86% | -33.33% |
% of Gross Profit | 1.28% | 1.56% | 0.7% |
Operating Expenses | $15.55M | $34.88M | $9.150M |
YoY Change | 69.89% | 51.22% | -12.52% |
Operating Profit | -$12.57M | -$42.07M | -$6.275M |
YoY Change | 100.27% | 68.95% | -14.44% |
Interest Expense | $53.00K | $0.00 | $10.00K |
YoY Change | 430.0% | -90.0% | |
% of Operating Profit | |||
Other Income/Expense, Net | -$1.106M | -$3.371M | -$1.250M |
YoY Change | -11.52% | -32.71% | -9.42% |
Pretax Income | -$13.62M | -$45.44M | -$7.520M |
YoY Change | 81.12% | 51.91% | -12.66% |
Income Tax | |||
% Of Pretax Income | |||
Net Earnings | -$13.62M | -$45.40M | -$7.517M |
YoY Change | 81.19% | 51.8% | -12.68% |
Net Earnings / Revenue | -434.45% | -426.33% | -248.58% |
Basic Earnings Per Share | -$0.50 | ||
Diluted Earnings Per Share | -$148.7K | -$0.50 | -$113.9K |
COMMON SHARES | |||
Basic Shares Outstanding | 91.61M shares | 91.57M shares | 58.82M shares |
Diluted Shares Outstanding | 91.57M shares |
Balance Sheet
Concept | 2021 Q4 | 2021 | 2020 Q4 |
---|---|---|---|
SHORT-TERM ASSETS | |||
Cash & Short-Term Investments | $115.9M | $115.9M | $168.5M |
YoY Change | -31.23% | -31.23% | 721.95% |
Cash & Equivalents | $40.01M | $40.01M | $129.6M |
Short-Term Investments | $75.87M | $75.87M | $38.90M |
Other Short-Term Assets | $3.267M | $3.267M | $1.200M |
YoY Change | 172.25% | 172.25% | -7.69% |
Inventory | |||
Prepaid Expenses | |||
Receivables | $3.224M | $3.224M | $3.043M |
Other Receivables | $0.00 | $0.00 | $0.00 |
Total Short-Term Assets | $122.4M | $122.4M | $172.8M |
YoY Change | -29.16% | -29.18% | 590.93% |
LONG-TERM ASSETS | |||
Property, Plant & Equipment | $505.0K | $6.254M | $663.0K |
YoY Change | -23.83% | -13.14% | 330.52% |
Goodwill | $8.982M | $9.000M | |
YoY Change | -0.2% | 0.0% | |
Intangibles | |||
YoY Change | |||
Long-Term Investments | $23.96M | $23.96M | $14.60M |
YoY Change | 64.14% | 64.14% | |
Other Assets | $0.00 | $726.0K | $3.000K |
YoY Change | -100.0% | -9.25% | 0.0% |
Total Long-Term Assets | $39.93M | $39.93M | $31.61M |
YoY Change | 26.32% | 26.35% | 212.81% |
TOTAL ASSETS | |||
Total Short-Term Assets | $122.4M | $122.4M | $172.8M |
Total Long-Term Assets | $39.93M | $39.93M | $31.61M |
Total Assets | $162.3M | $162.3M | $204.4M |
YoY Change | -20.58% | -20.6% | 482.1% |
SHORT-TERM LIABILITIES | |||
YoY Change | |||
Accounts Payable | $6.417M | $6.417M | $4.166M |
YoY Change | 54.03% | 52.79% | -6.7% |
Accrued Expenses | $6.339M | $7.021M | $3.625M |
YoY Change | 74.87% | 30.02% | 89.79% |
Deferred Revenue | |||
YoY Change | |||
Short-Term Debt | $0.00 | $0.00 | $0.00 |
YoY Change | |||
Long-Term Debt Due | $0.00 | $0.00 | $557.0K |
YoY Change | -100.0% | -100.0% | |
Total Short-Term Liabilities | $13.44M | $13.44M | $10.08M |
YoY Change | 33.33% | 33.05% | 54.09% |
LONG-TERM LIABILITIES | |||
Long-Term Debt | $0.00 | $0.00 | $334.0K |
YoY Change | -100.0% | -100.0% | |
Other Long-Term Liabilities | $0.00 | $58.16M | $334.0K |
YoY Change | -100.0% | -8.13% | |
Total Long-Term Liabilities | $0.00 | $58.16M | $668.0K |
YoY Change | -100.0% | -8.56% | |
TOTAL LIABILITIES | |||
Total Short-Term Liabilities | $13.44M | $13.44M | $10.08M |
Total Long-Term Liabilities | $0.00 | $58.16M | $668.0K |
Total Liabilities | $71.59M | $71.59M | $73.69M |
YoY Change | -2.84% | -2.86% | 6.77% |
SHAREHOLDERS EQUITY | |||
Retained Earnings | -$1.092B | -$1.047B | |
YoY Change | 4.34% | 2.94% | |
Common Stock | $1.183B | $1.178B | |
YoY Change | 0.47% | 19.78% | |
Preferred Stock | |||
YoY Change | |||
Treasury Stock (at cost) | |||
YoY Change | |||
Treasury Stock Shares | |||
Shareholders Equity | $90.71M | $90.71M | $130.7M |
YoY Change | |||
Total Liabilities & Shareholders Equity | $162.3M | $162.3M | $204.4M |
YoY Change | -20.58% | -20.6% | 482.1% |
Cashflow Statement
Concept | 2021 Q4 | 2021 | 2020 Q4 |
---|---|---|---|
OPERATING ACTIVITIES | |||
Net Income | -$13.62M | -$45.40M | -$7.517M |
YoY Change | 81.19% | 51.8% | -12.68% |
Depreciation, Depletion And Amortization | $38.00K | $158.0K | $20.00K |
YoY Change | 90.0% | 12.86% | -33.33% |
Cash From Operating Activities | -$8.171M | -$37.60M | -$5.720M |
YoY Change | 42.85% | 46.08% | 2.14% |
INVESTING ACTIVITIES | |||
Capital Expenditures | $0.00 | $0.00 | -$20.00K |
YoY Change | -100.0% | -100.0% | |
Acquisitions | |||
YoY Change | |||
Other Investing Activities | -$3.523M | -$47.90M | -$53.45M |
YoY Change | -93.41% | -0.98% | -3570.78% |
Cash From Investing Activities | -$3.523M | -$47.90M | -$53.47M |
YoY Change | -93.41% | -2.35% | -3549.68% |
FINANCING ACTIVITIES | |||
Cash Dividend Paid | |||
YoY Change | |||
Common Stock Issuance & Retirement, Net | $0.00 | ||
YoY Change | -100.0% | ||
Debt Paid & Issued, Net | |||
YoY Change | |||
Cash From Financing Activities | -1.312M | -$4.172M | 165.2M |
YoY Change | -100.79% | -102.21% | -15687.74% |
NET CHANGE | |||
Cash From Operating Activities | -8.171M | -$37.60M | -5.720M |
Cash From Investing Activities | -3.523M | -$47.90M | -53.47M |
Cash From Financing Activities | -1.312M | -$4.172M | 165.2M |
Net Change In Cash | -13.01M | -$89.69M | 106.0M |
YoY Change | -112.27% | -178.65% | -2175.15% |
FREE CASH FLOW | |||
Cash From Operating Activities | -$8.171M | -$37.60M | -$5.720M |
Capital Expenditures | $0.00 | $0.00 | -$20.00K |
Free Cash Flow | -$8.171M | -$37.60M | -$5.700M |
YoY Change | 43.35% | 42.34% | 1.79% |
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Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.50 | |
CY2021 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.50 | |
CY2020 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.61 | |
CY2020 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.61 | |
CY2019 | us-gaap |
Earnings Per Share Basic
EarningsPerShareBasic
|
-0.97 | |
CY2019 | us-gaap |
Earnings Per Share Diluted
EarningsPerShareDiluted
|
-0.97 | |
CY2021 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
91569154 | shares |
CY2021 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
91569154 | shares |
CY2020 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
48670381 | shares |
CY2020 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
48670381 | shares |
CY2019 | us-gaap |
Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
|
33180516 | shares |
CY2019 | us-gaap |
Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
|
33180516 | shares |
CY2021 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
-106000 | USD |
CY2020 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
-3000 | USD |
CY2021 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-45542000 | USD |
CY2019 | us-gaap |
Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
|
0 | USD |
CY2020 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-29911000 | USD |
CY2019 | us-gaap |
Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
|
-32141000 | USD |
CY2018Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
-4496000 | USD |
CY2019 | us-gaap |
Stock Issued During Period Value Other
StockIssuedDuringPeriodValueOther
|
68000 | USD |
CY2019 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
2658000 | USD |
CY2019 | us-gaap |
Stock Issued During Period Value Restricted Stock Award Forfeitures
StockIssuedDuringPeriodValueRestrictedStockAwardForfeitures
|
0 | USD |
CY2019 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-32141000 | USD |
CY2019Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
-33911000 | USD |
CY2020 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
2698000 | USD |
CY2020 | us-gaap |
Stock Issued During Period Value Other
StockIssuedDuringPeriodValueOther
|
58000 | USD |
CY2020 | us-gaap |
Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
|
15965000 | USD |
CY2020 | cris |
Issuance Of Common Stock Under Registration Statement Net Of Issuance Costs Value
IssuanceOfCommonStockUnderRegistrationStatementNetOfIssuanceCostsValue
|
159031000 | USD |
CY2020 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
727000 | USD |
CY2020 | us-gaap |
Marketable Securities Unrealized Gain Loss
MarketableSecuritiesUnrealizedGainLoss
|
-3000 | USD |
CY2020 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-29908000 | USD |
CY2020Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
130670000 | USD |
CY2021 | us-gaap |
Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
|
5279000 | USD |
CY2021 | us-gaap |
Stock Issued During Period Value Other
StockIssuedDuringPeriodValueOther
|
135000 | USD |
CY2021 | us-gaap |
Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
|
165000 | USD |
CY2021 | us-gaap |
Marketable Securities Unrealized Gain Loss
MarketableSecuritiesUnrealizedGainLoss
|
-106000 | USD |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-45436000 | USD |
CY2021Q4 | us-gaap |
Stockholders Equity
StockholdersEquity
|
90707000 | USD |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-45436000 | USD |
CY2020 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-29908000 | USD |
CY2019 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-32141000 | USD |
CY2021 | us-gaap |
Depreciation And Amortization
DepreciationAndAmortization
|
158000 | USD |
CY2020 | us-gaap |
Depreciation And Amortization
DepreciationAndAmortization
|
144000 | USD |
CY2019 | us-gaap |
Depreciation And Amortization
DepreciationAndAmortization
|
125000 | USD |
CY2021 | cris |
Non Cash Lease Expense
NonCashLeaseExpense
|
828000 | USD |
CY2020 | cris |
Non Cash Lease Expense
NonCashLeaseExpense
|
605000 | USD |
CY2019 | cris |
Non Cash Lease Expense
NonCashLeaseExpense
|
956000 | USD |
CY2021 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
5279000 | USD |
CY2020 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
2698000 | USD |
CY2019 | us-gaap |
Share Based Compensation
ShareBasedCompensation
|
2658000 | USD |
CY2021 | us-gaap |
Amortization Of Financing Costs
AmortizationOfFinancingCosts
|
0 | USD |
CY2020 | us-gaap |
Amortization Of Financing Costs
AmortizationOfFinancingCosts
|
0 | USD |
CY2019 | us-gaap |
Amortization Of Financing Costs
AmortizationOfFinancingCosts
|
8000 | USD |
CY2021 | cris |
Non Cash Imputed Interest Expense Net Of Imputed Interest
NonCashImputedInterestExpenseNetOfImputedInterest
|
36000 | USD |
CY2020 | cris |
Non Cash Imputed Interest Expense Net Of Imputed Interest
NonCashImputedInterestExpenseNetOfImputedInterest
|
45000 | USD |
CY2019 | cris |
Non Cash Imputed Interest Expense Net Of Imputed Interest
NonCashImputedInterestExpenseNetOfImputedInterest
|
287000 | USD |
CY2021 | us-gaap |
Accretion Amortization Of Discounts And Premiums Investments
AccretionAmortizationOfDiscountsAndPremiumsInvestments
|
-1402000 | USD |
CY2020 | us-gaap |
Accretion Amortization Of Discounts And Premiums Investments
AccretionAmortizationOfDiscountsAndPremiumsInvestments
|
-33000 | USD |
CY2019 | us-gaap |
Accretion Amortization Of Discounts And Premiums Investments
AccretionAmortizationOfDiscountsAndPremiumsInvestments
|
64000 | USD |
CY2021 | cris |
Gain Loss On Forgiveness Of Ppp Loan
GainLossOnForgivenessOfPPPLoan
|
890000 | USD |
CY2020 | cris |
Gain Loss On Forgiveness Of Ppp Loan
GainLossOnForgivenessOfPPPLoan
|
0 | USD |
CY2019 | cris |
Gain Loss On Forgiveness Of Ppp Loan
GainLossOnForgivenessOfPPPLoan
|
0 | USD |
CY2021 | us-gaap |
Gains Losses On Extinguishment Of Debt
GainsLossesOnExtinguishmentOfDebt
|
0 | USD |
CY2020 | us-gaap |
Gains Losses On Extinguishment Of Debt
GainsLossesOnExtinguishmentOfDebt
|
0 | USD |
CY2019 | us-gaap |
Gains Losses On Extinguishment Of Debt
GainsLossesOnExtinguishmentOfDebt
|
-3495000 | USD |
CY2021 | us-gaap |
Gain Loss On Disposition Of Assets
GainLossOnDispositionOfAssets
|
0 | USD |
CY2020 | us-gaap |
Gain Loss On Disposition Of Assets
GainLossOnDispositionOfAssets
|
-24000 | USD |
CY2019 | us-gaap |
Gain Loss On Disposition Of Assets
GainLossOnDispositionOfAssets
|
-29000 | USD |
CY2021 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
181000 | USD |
CY2020 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
-201000 | USD |
CY2019 | us-gaap |
Increase Decrease In Accounts Receivable
IncreaseDecreaseInAccountsReceivable
|
380000 | USD |
CY2021 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
2049000 | USD |
CY2020 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
153000 | USD |
CY2019 | us-gaap |
Increase Decrease In Prepaid Deferred Expense And Other Assets
IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
|
237000 | USD |
CY2021 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
4965000 | USD |
CY2020 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
1000000 | USD |
CY2019 | us-gaap |
Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
|
60000 | USD |
CY2021 | us-gaap |
Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
|
-1731000 | USD |
CY2020 | us-gaap |
Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
|
-428000 | USD |
CY2019 | us-gaap |
Increase Decrease In Operating Lease Liability
IncreaseDecreaseInOperatingLeaseLiability
|
-1001000 | USD |
CY2021 | us-gaap |
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities
AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities
|
7817000 | USD |
CY2020 | us-gaap |
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities
AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities
|
4169000 | USD |
CY2019 | us-gaap |
Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities
AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivities
|
5936000 | USD |
CY2021 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-37619000 | USD |
CY2020 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-25739000 | USD |
CY2019 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-26205000 | USD |
CY2021 | us-gaap |
Payments To Acquire Marketable Securities
PaymentsToAcquireMarketableSecurities
|
93125000 | USD |
CY2020 | us-gaap |
Payments To Acquire Marketable Securities
PaymentsToAcquireMarketableSecurities
|
53449000 | USD |
CY2019 | us-gaap |
Payments To Acquire Marketable Securities
PaymentsToAcquireMarketableSecurities
|
11465000 | USD |
CY2021 | us-gaap |
Proceeds From Sale And Maturity Of Marketable Securities
ProceedsFromSaleAndMaturityOfMarketableSecurities
|
45230000 | USD |
CY2020 | us-gaap |
Proceeds From Sale And Maturity Of Marketable Securities
ProceedsFromSaleAndMaturityOfMarketableSecurities
|
5078000 | USD |
CY2019 | us-gaap |
Proceeds From Sale And Maturity Of Marketable Securities
ProceedsFromSaleAndMaturityOfMarketableSecurities
|
7050000 | USD |
CY2021 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
0 | USD |
CY2020 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
677000 | USD |
CY2019 | us-gaap |
Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
|
41000 | USD |
CY2021 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-47895000 | USD |
CY2020 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-49048000 | USD |
CY2019 | us-gaap |
Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
|
-4456000 | USD |
CY2021 | us-gaap |
Proceeds From Issuance Of Debt
ProceedsFromIssuanceOfDebt
|
0 | USD |
CY2020 | us-gaap |
Proceeds From Issuance Of Debt
ProceedsFromIssuanceOfDebt
|
891000 | USD |
CY2019 | us-gaap |
Proceeds From Issuance Of Debt
ProceedsFromIssuanceOfDebt
|
0 | USD |
CY2021 | cris |
Proceeds From Issuance Of Private Placement Net Of Issuance Costs
ProceedsFromIssuanceOfPrivatePlacementNetOfIssuanceCosts
|
0 | USD |
CY2020 | cris |
Proceeds From Issuance Of Private Placement Net Of Issuance Costs
ProceedsFromIssuanceOfPrivatePlacementNetOfIssuanceCosts
|
17500000 | USD |
CY2019 | cris |
Proceeds From Issuance Of Private Placement Net Of Issuance Costs
ProceedsFromIssuanceOfPrivatePlacementNetOfIssuanceCosts
|
0 | USD |
CY2021 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
USD | |
CY2020 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
1535000 | USD |
CY2019 | us-gaap |
Payments Of Stock Issuance Costs
PaymentsOfStockIssuanceCosts
|
0 | USD |
CY2021 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
0 | USD |
CY2020 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
159447000 | USD |
CY2019 | us-gaap |
Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
|
0 | USD |
CY2021 | cris |
Proceeds From Royalty Purchase Agreement
ProceedsFromRoyaltyPurchaseAgreement
|
0 | USD |
CY2020 | cris |
Proceeds From Royalty Purchase Agreement
ProceedsFromRoyaltyPurchaseAgreement
|
0 | USD |
CY2019 | cris |
Proceeds From Royalty Purchase Agreement
ProceedsFromRoyaltyPurchaseAgreement
|
65000000 | USD |
CY2021 | cris |
Paymentsof Issuance Costs On Royalty Interest Purchase Agreement
PaymentsofIssuanceCostsOnRoyaltyInterestPurchaseAgreement
|
0 | USD |
CY2020 | cris |
Paymentsof Issuance Costs On Royalty Interest Purchase Agreement
PaymentsofIssuanceCostsOnRoyaltyInterestPurchaseAgreement
|
0 | USD |
CY2019 | cris |
Paymentsof Issuance Costs On Royalty Interest Purchase Agreement
PaymentsofIssuanceCostsOnRoyaltyInterestPurchaseAgreement
|
584000 | USD |
CY2021 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans
|
300000 | USD |
CY2020 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans
|
785000 | USD |
CY2019 | us-gaap |
Proceeds From Issuance Of Shares Under Incentive And Share Based Compensation Plans
ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlans
|
68000 | USD |
CY2021 | cris |
Payments Of Future Royalty Liability Net Of Imputed Interest
PaymentsOfFutureRoyaltyLiabilityNetOfImputedInterest
|
4472000 | USD |
CY2020 | cris |
Payments Of Future Royalty Liability Net Of Imputed Interest
PaymentsOfFutureRoyaltyLiabilityNetOfImputedInterest
|
4287000 | USD |
CY2019 | cris |
Payments Of Future Royalty Liability Net Of Imputed Interest
PaymentsOfFutureRoyaltyLiabilityNetOfImputedInterest
|
2226000 | USD |
CY2021 | us-gaap |
Repayments Of Long Term Lines Of Credit
RepaymentsOfLongTermLinesOfCredit
|
0 | USD |
CY2020 | us-gaap |
Repayments Of Long Term Lines Of Credit
RepaymentsOfLongTermLinesOfCredit
|
0 | USD |
CY2019 | us-gaap |
Repayments Of Long Term Lines Of Credit
RepaymentsOfLongTermLinesOfCredit
|
37162000 | USD |
CY2021 | us-gaap |
Repayments Of Debt
RepaymentsOfDebt
|
0 | USD |
CY2020 | us-gaap |
Repayments Of Debt
RepaymentsOfDebt
|
0 | USD |
CY2019 | us-gaap |
Repayments Of Debt
RepaymentsOfDebt
|
1825000 | USD |
CY2021 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
-4172000 | USD |
CY2020 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
188814000 | USD |
CY2019 | us-gaap |
Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
|
23271000 | USD |
CY2021 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
-89686000 | USD |
CY2020 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
114027000 | USD |
CY2019 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect
|
-7390000 | USD |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
130426000 | USD |
CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
16399000 | USD |
CY2018Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
23789000 | USD |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
40740000 | USD |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
130426000 | USD |
CY2019Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
16399000 | USD |
CY2021 | cris |
Increase Decrease In Accounts Payable Non Cash Issuance Costs
IncreaseDecreaseInAccountsPayableNonCashIssuanceCosts
|
0 | USD |
CY2020 | cris |
Increase Decrease In Accounts Payable Non Cash Issuance Costs
IncreaseDecreaseInAccountsPayableNonCashIssuanceCosts
|
416000 | USD |
CY2019 | cris |
Increase Decrease In Accounts Payable Non Cash Issuance Costs
IncreaseDecreaseInAccountsPayableNonCashIssuanceCosts
|
0 | USD |
CY2021 | cris |
Non Cash Commitment Shares Issued To Aspire Capital
NonCashCommitmentSharesIssuedToAspireCapital
|
0 | USD |
CY2020 | cris |
Non Cash Commitment Shares Issued To Aspire Capital
NonCashCommitmentSharesIssuedToAspireCapital
|
900000 | USD |
CY2019 | cris |
Non Cash Commitment Shares Issued To Aspire Capital
NonCashCommitmentSharesIssuedToAspireCapital
|
0 | USD |
CY2021 | us-gaap |
Interest Paid Net
InterestPaidNet
|
4437000 | USD |
CY2020 | us-gaap |
Interest Paid Net
InterestPaidNet
|
5050000 | USD |
CY2019 | us-gaap |
Interest Paid Net
InterestPaidNet
|
4716000 | USD |
CY2021 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
0 | USD |
CY2020 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
7169000 | USD |
CY2019 | us-gaap |
Right Of Use Asset Obtained In Exchange For Operating Lease Liability
RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability
|
0 | USD |
CY2021 | us-gaap |
Nature Of Operations
NatureOfOperations
|
Nature of Business<div style="margin-top:6pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Curis, Inc. is a biotechnology company focused on the development of first-in-class and innovative therapeutics for the treatment of cancer. Throughout these consolidated financial statements, Curis, Inc. and our wholly owned subsidiaries are collectively referred to as “the Company,” “Curis,” “we,” “us,” or “our.”</span></div><div style="margin-top:6pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company conducts its research and development programs both internally and through strategic collaborations. The Company’s clinical stage drug candidates include emavusertib, previously CA-4948, an orally available small molecule inhibitor of Interleukin-1 receptor associated kinase 4 (“IRAK4”); CI-8993, a monoclonal antibody designed to antagonize the V-domain Ig suppressor of T cell activation (“VISTA”) signaling pathway; fimepinostat, a small molecule that potently inhibits the activity of histone deacetylase and phosphotidyl-inositol 3 kinase enzymes; and CA-170, a small molecule antagonist of VISTA and PDL1.</span></div><div style="margin-top:9pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company is party to a collaboration with Genentech Inc. (“Genentech”), a member of the Roche Group, under which Genentech and F. Hoffmann-La Roche Ltd (“Roche”) are commercializing Erivedge® (vismodegib), a first-in-class orally administered small molecule Hedgehog signaling pathway antagonist. Erivedge is approved for the treatment of advanced basal cell carcinoma (“BCC”).</span></div><div style="margin-top:9pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In January 2015, the Company entered into an exclusive collaboration agreement with Aurigene Discovery Technologies Limited (“Aurigene”) for the discovery, development and commercialization of small molecule compounds in the areas of immuno-oncology and precision oncology, which was amended in September 2016 and February 2020. </span></div><div style="text-indent:22.5pt"><span><br/></span></div><div style="text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">In addition, the Company is a party to an option and license agreement with ImmuNext. Pursuant to the terms of the option and license agreement, the Company has an option, exercisable for a specified period as set forth in the option and license agreement, to obtain an exclusive license to develop and commercialize certain VISTA antagonizing compounds, including ImmuNext's lead compound, CI-8993, and products containing these compounds in the field of oncology.</span></div><div style="text-indent:22.5pt"><span><br/></span></div><div style="text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The COVID-19 pandemic has had and may continue to have an adverse effect on the Company’s business, financial condition, results of operations, and prospects. With respect to ongoing clinical trials, the anticipated timing of enrollment and the overall timelines of the trials have experienced delays and could be further delayed to the extent the Company experiences further delays in enrollment due to the COVID-19 pandemic. The Company’s ability to collect patient data in a timely fashion may also be impacted. The Company also experienced delays in closing down its clinical trial sites related to its fimepinostat and CA-170 trials due to restrictions on non-essential workers imposed at those sites in response to COVID-19, which delayed the winding down of these trials. In addition, the Company and its collaborators, third-party contract manufacturers, contract research organizations and clinical sites could experience delays or disruptions in supply and release of product candidates and/or procuring items that are essential for its research and development activities, including, for example, raw materials used in the manufacturing of its product candidates, basic medical and laboratory supplies used in its clinical trials or preclinical studies, or animals that are used for preclinical testing, in each case, for which there may be shortages or supply chain disruptions as a result of the pandemic. The Company cannot be certain what the overall impact of the COVID-19 pandemic will be on its business.</span></div><div style="margin-top:6pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company is subject to risks common to companies in the biotechnology industry as well as risks that are specific to the Company’s business, including, but not limited to: the Company’s ability to obtain adequate financing to fund its operations; the Company’s ability to advance and expand its research and development programs; the impacts of the COVID-19 pandemic and responsive actions related thereto; the Company’s reliance on Roche and Genentech to successfully commercialize Erivedge in the approved indication of advanced BCC and to progress its clinical development in indications other than BCC; the ability of the Company and its wholly owned subsidiary, Curis Royalty, LLC (“Curis Royalty”) to satisfy the terms of the royalty interest purchase agreement (the “Oberland Purchase Agreement”) with TPC Investments I LP and TPC Investments II LP ("the Purchasers"), each of which is a Delaware limited partnership managed by Oberland Capital Management, LLC, and Lind SA LLC ("the Agent"), a Delaware limited liability company managed by Oberland Capital Management, LLC, as collateral agent for the Purchasers; the Company’s ability to obtain and maintain necessary intellectual property protection; development by the Company’s competitors of new or better technological innovations; the Company’s ability to comply with regulatory requirements; the Company's ability to obtain and maintain applicable regulatory approvals and commercialize any approved product candidates and the Company’s ability to execute on its overall business strategies.</span></div><div style="margin-top:9pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company’s future operating results will largely depend on the progress of drug candidates currently in its development pipeline and the magnitude of payments that it may receive and make under its current and potential future collaborations. The results of the Company’s operations have varied and will likely continue to vary significantly from year to </span></div><div style="margin-top:9pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">year and quarter to quarter and depend on a number of factors, including, but not limited to the timing, outcome and cost of the Company’s preclinical studies and clinical trials for its drug candidates.</span></div><div style="margin-top:9pt;text-indent:24.75pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company will require substantial funds to maintain research and development programs and support operations. The Company has incurred losses and negative cash flows from operations since its inception. As of December 31, 2021, the Company had an accumulated deficit of approximately $1.1 billion, incurred a loss of $45.4 million and used $37.6 million of cash in operations. The Company expects to continue to generate operating losses in the foreseeable future. The Company anticipates that its $139.8 million of existing cash, cash equivalents and investments at December 31, 2021 will be sufficient to fund operations for at least 12 months from the date of issuance of these financial statements. </span></div><div style="margin-top:9pt;text-indent:24.75pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company’s ability to raise additional funds will depend, among other factors, on financial, economic and market conditions, many of which are outside of its control and it may be unable to raise financing when needed, or on terms favorable to the Company. If necessary funds are not available, the Company will have to delay, reduce the scope of, or eliminate some of its development programs, potentially delaying the time to market for or preventing the marketing of any of its product candidates.</span></div> | |
CY2021Q4 | us-gaap |
Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
|
-1100000000 | USD |
CY2021 | us-gaap |
Net Income Loss
NetIncomeLoss
|
-45400000 | USD |
CY2021 | us-gaap |
Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
|
-37600000 | USD |
CY2021Q4 | us-gaap |
Cash Cash Equivalents And Short Term Investments
CashCashEquivalentsAndShortTermInvestments
|
139800000 | USD |
CY2021 | us-gaap |
Use Of Estimates
UseOfEstimates
|
Use of Estimates and Assumptions<div style="margin-top:9pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The preparation of the Company’s consolidated financial statements in conformity with accounting principles generally accepted in the United States requires management to make estimates and assumptions that affect the reported amounts and disclosure of revenue, expenses and certain assets and liabilities at the balance sheet date. Such estimates include revenue recognition, including estimates related to the performance obligations under the Company’s collaboration agreements; the estimated repayment term of the Company’s debt and related short and long-term classification; the collectability of receivables; the carrying value of property and equipment and goodwill; the assumptions used in the Company’s valuation of stock-based compensation and the value of certain investments and liabilities. Actual results may differ from such estimates.</span></div><div style="margin-top:9pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The extent to which COVID-19 has had and may continue to have impacts on the Company’s business and financial results will depend on numerous evolving factors including, but not limited to: the magnitude and duration of the COVID-19 pandemic, the extent to which it has impacted and will continue to impact worldwide macroeconomic conditions including interest rates, employment rates and health insurance coverage, the speed of the anticipated recovery, and governmental and business responses to the pandemic. The Company assessed certain accounting matters that generally require consideration of forecasted financial information in context with the information reasonably available to the Company and the unknown future impacts of COVID-19 as of December 31, 2021 and through the date of this report. The Company’s future assessment of the magnitude and duration of the COVID-19 pandemic, as well as other factors, could result in material impacts to the Company’s consolidated financial statements in future reporting periods.</span></div> | |
CY2021Q4 | us-gaap |
Restricted Cash
RestrictedCash
|
700000 | USD |
CY2020Q4 | us-gaap |
Restricted Cash
RestrictedCash
|
800000 | USD |
CY2021Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
40700000 | USD |
CY2020Q4 | us-gaap |
Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents
CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents
|
130400000 | USD |
CY2021 | us-gaap |
Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
|
Concentrations and Significant Customer Information<div style="margin-top:6pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">Financial instruments which potentially subject the Company to concentrations of credit risk consist principally of cash and cash equivalents, marketable securities, and accounts receivable. The Company maintains deposits in federally insured financial institutions in excess of federally insured limits. Management believes that the Company is not exposed to significant credit risk due to the financial position of the depository institutions in which those deposits are held. The Company’s credit risk related to investments is reduced as a result of the Company’s policy to limit the amount invested in any one issue. As of December 31, 2021, the Company did not have a material concentration in any single investment. </span></div><div style="margin-top:6pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company's operations are located entirely within the U.S. The Company focus is primarily on the development of first-in-class and innovative therapeutics for the treatment of cancer. The Company's customer, Genentech, accounted for 100%, 98%, and 100% of the total gross revenues for the years ending December 31, 2021, 2020, and 2019, respectively.</span></div><div style="margin-top:6pt;text-indent:22.5pt"><span style="color:#000000;font-family:'Times New Roman',sans-serif;font-size:10pt;font-weight:400;line-height:120%">The Company’s accounts receivable at December 31, 2021 and December 31, 2020 represents amounts due from collaborators, primarily for royalties earned on sales of Erivedge by Genentech and Roche.</span></div>The Company relies on third-parties to supply certain raw materials necessary to produce its drug candidates, including emavusertib (CA-4948) and CI-8993 for preclinical studies and clinical trials. There are a small number of suppliers for certain raw materials that the Company uses to manufacture its drug candidates. | |
CY2021Q4 | us-gaap |
Goodwill
Goodwill
|
9000000.0 | USD |
CY2020Q4 | us-gaap |
Goodwill
Goodwill
|
9000000.0 | USD |
CY2020 | us-gaap |
Goodwill Impairment Loss
GoodwillImpairmentLoss
|
0 | USD |
CY2021 | us-gaap |
Goodwill Impairment Loss
GoodwillImpairmentLoss
|
0 | USD |
CY2021 | cris |
Royalty Purchase Agreement Percentage Of Royalty Payments
RoyaltyPurchaseAgreementPercentageOfRoyaltyPayments
|
0.05 | |
CY2021 | cris |
Royalty Purchase Agreement Royalty Payment Period
RoyaltyPurchaseAgreementRoyaltyPaymentPeriod
|
P10Y | |
CY2021 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
10363769 | shares |
CY2020 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
8668005 | shares |
CY2019 | us-gaap |
Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
|
6158026 | shares |
CY2021Q4 | cris |
Debt Securities Available For Sale Accrued Interest
DebtSecuritiesAvailableForSaleAccruedInterest
|
400000 | USD |
CY2020Q4 | cris |
Debt Securities Available For Sale Accrued Interest
DebtSecuritiesAvailableForSaleAccruedInterest
|
300000 | USD |
CY2021Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
99943000 | USD |
CY2021Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
|
0 | USD |
CY2021Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
|
109000 | USD |
CY2021Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
99834000 | USD |
CY2020Q4 | us-gaap |
Available For Sale Debt Securities Amortized Cost Basis
AvailableForSaleDebtSecuritiesAmortizedCostBasis
|
53451000 | USD |
CY2020Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Gain Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax
|
1000 | USD |
CY2020Q4 | us-gaap |
Available For Sale Debt Securities Accumulated Gross Unrealized Loss Before Tax
AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax
|
4000 | USD |
CY2020Q4 | us-gaap |
Available For Sale Securities Debt Securities
AvailableForSaleSecuritiesDebtSecurities
|
53448000 | USD |
CY2019 | us-gaap |
Debt Securities Available For Sale Change In Present Value Expense Reversal
DebtSecuritiesAvailableForSaleChangeInPresentValueExpenseReversal
|
0 | USD |
CY2021 | us-gaap |
Debt Securities Available For Sale Change In Present Value Expense Reversal
DebtSecuritiesAvailableForSaleChangeInPresentValueExpenseReversal
|
0 | USD |
CY2020 | us-gaap |
Debt Securities Available For Sale Change In Present Value Expense Reversal
DebtSecuritiesAvailableForSaleChangeInPresentValueExpenseReversal
|
0 | USD |
CY2021Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
2225000 | USD |
CY2020Q4 | us-gaap |
Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
|
2066000 | USD |
CY2021Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
2730000 | USD |
CY2020Q4 | us-gaap |
Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
|
2729000 | USD |
CY2021Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
505000 | USD |
CY2020Q4 | us-gaap |
Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
|
663000 | USD |
CY2021 | us-gaap |
Depreciation And Amortization
DepreciationAndAmortization
|
200000 | USD |
CY2020 | us-gaap |
Depreciation And Amortization
DepreciationAndAmortization
|
100000 | USD |
CY2019 | us-gaap |
Depreciation And Amortization
DepreciationAndAmortization
|
100000 | USD |
CY2021Q4 | us-gaap |
Accrued Salaries Current
AccruedSalariesCurrent
|
3260000 | USD |
CY2020Q4 | us-gaap |
Accrued Salaries Current
AccruedSalariesCurrent
|
2638000 | USD |
CY2021Q4 | cris |
Chemistry Manufacturing And Controls Costs
ChemistryManufacturingAndControlsCosts
|
2232000 | USD |
CY2020Q4 | cris |
Chemistry Manufacturing And Controls Costs
ChemistryManufacturingAndControlsCosts
|
0 | USD |
CY2021Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
644000 | USD |
CY2020Q4 | us-gaap |
Accrued Professional Fees Current
AccruedProfessionalFeesCurrent
|
307000 | USD |
CY2021Q4 | cris |
License Fees
LicenseFees
|
0 | USD |
CY2020Q4 | cris |
License Fees
LicenseFees
|
375000 | USD |
CY2021Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
203000 | USD |
CY2020Q4 | us-gaap |
Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
|
305000 | USD |
CY2021Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
6339000 | USD |
CY2020Q4 | us-gaap |
Accrued Liabilities Current
AccruedLiabilitiesCurrent
|
3625000 | USD |
CY2021Q4 | us-gaap |
Operating Lease Weighted Average Discount Rate Percent
OperatingLeaseWeightedAverageDiscountRatePercent
|
0.0995 | |
CY2021Q4 | us-gaap |
Lessee Operating Lease Remaining Lease Term
LesseeOperatingLeaseRemainingLeaseTerm
|
P7Y | |
CY2020Q2 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
9300000 | USD |
CY2021 | us-gaap |
Operating Lease Expense
OperatingLeaseExpense
|
2300000 | USD |
CY2021 | cris |
Operating Lease One Time Payment Tenant Improvements
OperatingLeaseOneTimePaymentTenantImprovements
|
1100000 | USD |
CY2021Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
5749000 | USD |
CY2020Q4 | us-gaap |
Operating Lease Right Of Use Asset
OperatingLeaseRightOfUseAsset
|
6578000 | USD |
CY2021Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
682000 | USD |
CY2020Q4 | us-gaap |
Operating Lease Liability Current
OperatingLeaseLiabilityCurrent
|
1731000 | USD |
CY2021Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
4358000 | USD |
CY2020Q4 | us-gaap |
Operating Lease Liability Noncurrent
OperatingLeaseLiabilityNoncurrent
|
5040000 | USD |
CY2021Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
5040000 | USD |
CY2020Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
6771000 | USD |
CY2020 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
1336000 | USD |
CY2019 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
1002000 | USD |
CY2021 | us-gaap |
Operating Lease Cost
OperatingLeaseCost
|
1353000000 | USD |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Next Twelve Months
LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths
|
1145000 | USD |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Two
LesseeOperatingLeaseLiabilityPaymentsDueYearTwo
|
1178000 | USD |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Three
LesseeOperatingLeaseLiabilityPaymentsDueYearThree
|
1213000 | USD |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Four
LesseeOperatingLeaseLiabilityPaymentsDueYearFour
|
1250000 | USD |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due Year Five
LesseeOperatingLeaseLiabilityPaymentsDueYearFive
|
1287000 | USD |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due After Year Five
LesseeOperatingLeaseLiabilityPaymentsDueAfterYearFive
|
433000 | USD |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Payments Due
LesseeOperatingLeaseLiabilityPaymentsDue
|
6506000 | USD |
CY2021Q4 | us-gaap |
Lessee Operating Lease Liability Undiscounted Excess Amount
LesseeOperatingLeaseLiabilityUndiscountedExcessAmount
|
1466000 | USD |
CY2021 | cris |
Share Based Compensation Plans
ShareBasedCompensationPlans
|
2 | plan |
CY2021Q4 | us-gaap |
Operating Lease Liability
OperatingLeaseLiability
|
5040000 | USD |
CY2021 | us-gaap |
Royalty Expense
RoyaltyExpense
|
500000 | USD |
CY2020 | us-gaap |
Royalty Expense
RoyaltyExpense
|
500000 | USD |
CY2019 | us-gaap |
Royalty Expense
RoyaltyExpense
|
500000 | USD |
CY2020Q2 | us-gaap |
Long Term Debt
LongTermDebt
|
900000 | USD |
CY2019Q1 | cris |
Royalty Purchase Agreement Interest Rate
RoyaltyPurchaseAgreementInterestRate
|
0.078 | |
CY2019Q1 | cris |
Royalty Purchase Agreement Transaction Fees And Closing Costs
RoyaltyPurchaseAgreementTransactionFeesAndClosingCosts
|
600000 | USD |
CY2020Q4 | cris |
Royalty Purchase Agreement Liability Carrying Value
RoyaltyPurchaseAgreementLiabilityCarryingValue
|
58235000 | USD |
CY2021 | cris |
Royalty Purchase Agreement Issuance Costs Capitalized Amortization
RoyaltyPurchaseAgreementIssuanceCostsCapitalizedAmortization
|
61000 | USD |
CY2021 | cris |
Royalty Purchase Agreement Accretion Expense
RoyaltyPurchaseAgreementAccretionExpense
|
4411000 | USD |
CY2021 | cris |
Payments Of Future Royalty Liability
PaymentsOfFutureRoyaltyLiability
|
8909000 | USD |
CY2021Q4 | cris |
Royalty Purchase Agreement Liability Carrying Value
RoyaltyPurchaseAgreementLiabilityCarryingValue
|
53798000 | USD |
CY2019Q4 | cris |
Royalty Purchase Agreement Liability Carrying Value
RoyaltyPurchaseAgreementLiabilityCarryingValue
|
62477000 | USD |
CY2020 | cris |
Royalty Purchase Agreement Issuance Costs Capitalized Amortization
RoyaltyPurchaseAgreementIssuanceCostsCapitalizedAmortization
|
61000 | USD |
CY2020 | cris |
Royalty Purchase Agreement Accretion Expense
RoyaltyPurchaseAgreementAccretionExpense
|
5034000 | USD |
CY2020 | cris |
Payments Of Future Royalty Liability
PaymentsOfFutureRoyaltyLiability
|
9337000 | USD |
CY2020Q4 | cris |
Royalty Purchase Agreement Liability Carrying Value
RoyaltyPurchaseAgreementLiabilityCarryingValue
|
58235000 | USD |
CY2020Q2 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
101250000 | shares |
CY2021Q2 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
151875000 | shares |
CY2021Q2 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
151875000 | shares |
CY2021Q4 | us-gaap |
Common Stock Shares Authorized
CommonStockSharesAuthorized
|
227812500 | shares |
CY2016Q3 | cris |
Collaboration Agreement Numberof Programs Licensed
CollaborationAgreementNumberofProgramsLicensed
|
4 | program |
CY2021 | cris |
Collaboration Agreement Numberof Programs Licensed
CollaborationAgreementNumberofProgramsLicensed
|
4 | program |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
|
720200 | shares |
CY2020Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
8668005 | shares |
CY2020Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
2.71 | |
CY2020 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P7Y11M23D | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
|
2006100 | shares |
CY2021 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
|
9.07 | |
CY2021 | us-gaap |
Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
|
98886 | shares |
CY2021 | us-gaap |
Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
|
1.67 | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriod
|
211450 | shares |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures And Expirations In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresAndExpirationsInPeriodWeightedAverageExercisePrice
|
10.09 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
|
10363769 | shares |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
|
3.80 | |
CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
|
P7Y4M28D | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
|
24749000 | USD |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber
|
6127217 | shares |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercisable Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice
|
3.24 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Aggregate Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingAggregateIntrinsicValue
|
24287000 | USD |
CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1
|
P6Y9M7D | |
CY2021Q4 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Exercisable Intrinsic Value1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1
|
16572000 | USD |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingNumber
|
10083019 | shares |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
7.25 | |
CY2021Q4 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
|
3.76 | |
CY2021 | us-gaap |
Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageRemainingContractualTerm1
|
P7Y4M13D | |
CY2020 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
0.84 | |
CY2019 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
|
0.85 | |
CY2021Q4 | us-gaap |
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized
|
10600000 | USD |
CY2021 | us-gaap |
Employee Service Share Based Compensation Nonvested Awards Total Compensation Cost Not Yet Recognized Period For Recognition1
EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1
|
P2Y1M6D | |
CY2021 | us-gaap |
Share Based Compensation Arrangement By Share Based Payment Award Options Exercises In Period Total Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisesInPeriodTotalIntrinsicValue
|
300000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
60759000 | USD |
CY2021 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
5279000 | USD |
CY2020 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
2698000 | USD |
CY2019 | us-gaap |
Allocated Share Based Compensation Expense
AllocatedShareBasedCompensationExpense
|
2658000 | USD |
CY2019 | us-gaap |
Employee Service Share Based Compensation Tax Benefit From Compensation Expense
EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense
|
0 | USD |
CY2021 | us-gaap |
Employee Service Share Based Compensation Tax Benefit From Compensation Expense
EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense
|
0 | USD |
CY2020 | us-gaap |
Employee Service Share Based Compensation Tax Benefit From Compensation Expense
EmployeeServiceShareBasedCompensationTaxBenefitFromCompensationExpense
|
0 | USD |
CY2021 | us-gaap |
Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
|
400000 | USD |
CY2020 | us-gaap |
Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
|
200000 | USD |
CY2019 | us-gaap |
Defined Contribution Plan Employer Discretionary Contribution Amount
DefinedContributionPlanEmployerDiscretionaryContributionAmount
|
200000 | USD |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.210 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.210 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
|
0.210 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.062 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.061 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
|
0.061 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
|
-0.035 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
|
-0.041 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
|
-0.027 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Other
EffectiveIncomeTaxRateReconciliationTaxCreditsOther
|
-0.029 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Other
EffectiveIncomeTaxRateReconciliationTaxCreditsOther
|
-0.023 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Tax Credits Other
EffectiveIncomeTaxRateReconciliationTaxCreditsOther
|
-0.046 | |
CY2021 | cris |
Effective Income Tax Reconciliation Net Operating Loss Expirations
EffectiveIncomeTaxReconciliationNetOperatingLossExpirations
|
-0.098 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
-0.006 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0.094 | |
CY2020 | cris |
Effective Income Tax Reconciliation Net Operating Loss Expirations
EffectiveIncomeTaxReconciliationNetOperatingLossExpirations
|
-0.298 | |
CY2019 | cris |
Effective Income Tax Reconciliation Net Operating Loss Expirations
EffectiveIncomeTaxReconciliationNetOperatingLossExpirations
|
-0.040 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
-0.002 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
|
0.003 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
|
0 | |
CY2021 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.142 | |
CY2020 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.040 | |
CY2019 | us-gaap |
Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
|
-0.298 | |
CY2021 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0 | |
CY2020 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0 | |
CY2019 | us-gaap |
Effective Income Tax Rate Continuing Operations
EffectiveIncomeTaxRateContinuingOperations
|
0 | |
CY2021Q4 | us-gaap |
Deferred Tax Assets Operating Loss Carryforwards
DeferredTaxAssetsOperatingLossCarryforwards
|
68802000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
|
14801000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Research
DeferredTaxAssetsTaxCreditCarryforwardsResearch
|
14923000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Other
DeferredTaxAssetsTaxCreditCarryforwardsOther
|
20096000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Other
DeferredTaxAssetsTaxCreditCarryforwardsOther
|
18778000 | USD |
CY2021Q4 | cris |
Deferred Tax Assets Depreciation And Amortization
DeferredTaxAssetsDepreciationAndAmortization
|
7493000 | USD |
CY2020Q4 | cris |
Deferred Tax Assets Depreciation And Amortization
DeferredTaxAssetsDepreciationAndAmortization
|
8478000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
37528000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets In Process Research And Development
DeferredTaxAssetsInProcessResearchAndDevelopment
|
34832000 | USD |
CY2021Q4 | cris |
Deferred Tax Assets Stock Options
DeferredTaxAssetsStockOptions
|
3344000 | USD |
CY2020Q4 | cris |
Deferred Tax Assets Stock Options
DeferredTaxAssetsStockOptions
|
6584000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense
DeferredTaxAssetsTaxDeferredExpense
|
916000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets Tax Deferred Expense
DeferredTaxAssetsTaxDeferredExpense
|
708000 | USD |
CY2021Q4 | cris |
Deferred Tax Assets Royalty Purchase Agreement
DeferredTaxAssetsRoyaltyPurchaseAgreement
|
14637000 | USD |
CY2020Q4 | cris |
Deferred Tax Assets Royalty Purchase Agreement
DeferredTaxAssetsRoyaltyPurchaseAgreement
|
15872000 | USD |
CY2021Q4 | cris |
Deferred Tax Assets Operating Lease Liability
DeferredTaxAssetsOperatingLeaseLiability
|
1371000 | USD |
CY2020Q4 | cris |
Deferred Tax Assets Operating Lease Liability
DeferredTaxAssetsOperatingLeaseLiability
|
1846000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
168988000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets Gross
DeferredTaxAssetsGross
|
162780000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
167424000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
160987000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets Net
DeferredTaxAssetsNet
|
1564000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets Net
DeferredTaxAssetsNet
|
1793000 | USD |
CY2021Q4 | cris |
Deferred Tax Liabilities Operating Lease Rightof Use Asset
DeferredTaxLiabilitiesOperatingLeaseRightofUseAsset
|
1564000 | USD |
CY2020Q4 | cris |
Deferred Tax Liabilities Operating Lease Rightof Use Asset
DeferredTaxLiabilitiesOperatingLeaseRightofUseAsset
|
1793000 | USD |
CY2021Q4 | us-gaap |
Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
|
1564000 | USD |
CY2020Q4 | us-gaap |
Deferred Income Tax Liabilities
DeferredIncomeTaxLiabilities
|
1793000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Liabilities
DeferredTaxLiabilities
|
0 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Liabilities
DeferredTaxLiabilities
|
0 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Other
DeferredTaxAssetsTaxCreditCarryforwardsOther
|
20100000 | USD |
CY2020Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Other
DeferredTaxAssetsTaxCreditCarryforwardsOther
|
18800000 | USD |
CY2019Q4 | us-gaap |
Deferred Tax Assets Tax Credit Carryforwards Other
DeferredTaxAssetsTaxCreditCarryforwardsOther
|
18100000 | USD |
CY2021Q4 | us-gaap |
Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
|
167400000 | USD |
CY2021 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
-6400000 | USD |
CY2020 | us-gaap |
Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
|
1200000 | USD |
CY2020Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
0 | USD |
CY2021Q4 | us-gaap |
Unrecognized Tax Benefits
UnrecognizedTaxBenefits
|
0 | USD |
CY2021Q4 | us-gaap |
Liability For Uncertain Tax Positions Current
LiabilityForUncertainTaxPositionsCurrent
|
0 | USD |
CY2020 | us-gaap |
Related Party Transaction Amounts Of Transaction
RelatedPartyTransactionAmountsOfTransaction
|
100000 | USD |
CY2019 | us-gaap |
Related Party Transaction Amounts Of Transaction
RelatedPartyTransactionAmountsOfTransaction
|
300000 | USD |
us-gaap |
Related Party Transaction Amounts Of Transaction
RelatedPartyTransactionAmountsOfTransaction
|
0 | USD | |
CY2021 | dei |
Auditor Firm
AuditorFirmId
|
238 |