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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Operating activities | |||||
| Net income | |||||
| Adjustments to reconcile net income to cash provided by operating activities: | |||||
| Depreciation and amortization | |||||
| Share-based compensation | |||||
| Collaborative research and development fee | |||||
| Loss on extinguishment of debt | |||||
| Non-cash interest expense | |||||
| Realized (gain) loss on equity investment | |||||
| Deferred income taxes | |||||
| Net (gains) losses on equity investments | |||||
| Other non-cash income and expenses | |||||
| Changes in operating assets and liabilities: | |||||
| Accounts receivable, net | |||||
| Inventory | |||||
| Prepaid and other assets | |||||
| Operating lease right-of-use assets and liabilities, net | |||||
| Accounts payable and accrued liabilities | |||||
| Accrued payroll and related expenses | |||||
| Deferred revenue and other liabilities | |||||
| Net cash provided by operating activities | |||||
| Investing activities | |||||
| Purchases of marketable securities | |||||
| Proceeds from sale and maturity of marketable securities | |||||
| Purchases of property and equipment | |||||
| Acquisitions, net of cash acquired | |||||
| Purchases of non-marketable equity securities | |||||
| Other investing activities | |||||
| Net cash provided by (used in) investing activities | |||||
| Financing activities | |||||
| Net proceeds from issuance of common stock | |||||
| Purchases of treasury stock | |||||
| Proceeds from issuance of convertible notes, net of issuance costs | |||||
| Purchases of capped call transactions | |||||
| Payments for conversions of senior convertible notes | |||||
| Repayments for maturity of senior convertible notes | |||||
| Other financing activities | |||||
| Net cash used in financing activities | |||||
| Effect of exchange rate changes on cash, cash equivalents and restricted cash | |||||
| Increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash, beginning of period | |||||
| Cash, cash equivalents and restricted cash, end of period | |||||
| Supplemental disclosure of non-cash investing and financing transactions: | |||||
| Shares issued for repurchase and conversions of senior convertible notes | |||||
| Shares received under note hedge upon conversion of 2023 Notes | |||||
| Acquisition of property and equipment included in accounts payable and accrued liabilities | |||||
| Supplemental cash flow information: | |||||
| Cash paid during the year for interest | |||||
| Cash paid during the year for income taxes | |||||
| Reconciliation of cash, cash equivalents and restricted cash, end of period: | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
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