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FY2025
12 months to Dec 31, 2025
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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FY2020
12 months to Dec 31, 2020
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FY2019
12 months to Dec 31, 2019
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Stock-based compensation | |||||
| Depreciation | |||||
| Amortization of operating lease right-of-use asset | |||||
| Amortization of debt discount | |||||
| Increase in fair value of derivative liabilities | |||||
| Imputed interest expense on 2025 bridge loans | |||||
| Change in fair value of warrant liabilities | |||||
| Extinguishment of the 2021 Award | |||||
| Write-off of fair value of derivative liabilities | |||||
| Loss on extinguishment of debt | |||||
| Loss on issuance of common stock | |||||
| Gain on debt conversion | |||||
| Gain on sales and disposals of property and equipment | |||||
| Changes in operating assets and liabilities: | |||||
| License and service receivable | |||||
| Unbilled receivable | |||||
| Prepaid expenses and other assets | |||||
| Accounts payable | |||||
| Accrued expenses | |||||
| Accrued interest | |||||
| Operating lease liabilities | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Proceeds from sales of property and equipment | |||||
| Proceeds from Sale of Other Property, Plant, and Equipment | |||||
| Net cash provided by investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from the issuance of common stock, pre-funded warrants, and common stock warrants, net of issuance costs | |||||
| Proceeds from the sale of common stock through ATM program, net of issuance costs | |||||
| Total proceeds from the sale of common stock through ATM program, net of issuance costs | |||||
| Proceeds from issuance of pre-funded warrants in connection with the 2025 PIPE transaction, net issuance costs | |||||
| Proceeds from debt financing obligation | |||||
| Repayment of term loan principal | |||||
| Proceeds (repayment) from advances from collaboration partners | |||||
| Net cash provided by (used in) financing activities | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at the beginning of the year | |||||
| Cash, cash equivalents and restricted cash at the end of the year | |||||
| Supplemental disclosure of cash flow activities: | |||||
| Cash paid for interest | |||||
| Noncash financing activities: | |||||
| Fair value of common stock and pre-funded warrants issued to loan holder | |||||
| Domicilium debt conversion, (principal of $7,366 and accrued interest of $1,131) | |||||
| Reconciliation of cash, cash equivalents and restricted cash to consolidated balance sheet: | |||||
| Cash and cash equivalents | |||||
| Restricted cash | |||||
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