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FY2025
12 months to Dec 31, 2025
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FY2024
12 months to Dec 31, 2024
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FY2023
12 months to Dec 31, 2023
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FY2022
12 months to Dec 31, 2022
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FY2021
12 months to Dec 31, 2021
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|---|---|---|---|---|---|
| Cash flows from operating activities: | |||||
| Net loss | |||||
| Adjustments to reconcile net loss to net cash used in operating activities: | |||||
| Stock-based compensation expense | |||||
| Depreciation and amortization expense | |||||
| Loss on disposal of property and equipment | |||||
| Gain on lease modification | |||||
| Impairment of long-lived assets | |||||
| Noncash lease expense | |||||
| Accretion of discount on marketable securities | |||||
| Changes in operating assets and liabilities: | |||||
| Prepaid expenses and other current assets | |||||
| Collaboration receivable | |||||
| Accounts payable | |||||
| Accrued expenses and other liabilities | |||||
| Operating lease liabilities | |||||
| Deferred revenue | |||||
| Net cash used in operating activities | |||||
| Cash flows from investing activities: | |||||
| Purchases of property and equipment | |||||
| Purchases of marketable securities | |||||
| Proceeds from maturities of marketable securities | |||||
| Net cash provided by (used in) investing activities | |||||
| Cash flows from financing activities: | |||||
| Proceeds from offerings of common stock and pre-funded warrants, net of underwriting discounts and commissions | |||||
| Prefunded Warrants | |||||
| At Market Offering | |||||
| Total proceeds from offerings of common stock and pre-funded warrants, net of underwriting discounts and commissions | |||||
| Payments of public offering costs | |||||
| Proceeds from issuance of common stock upon exercise of stock options and employee stock purchase plan | |||||
| Net cash provided by financing activities | |||||
| Net increase (decrease) in cash, cash equivalents and restricted cash | |||||
| Cash, cash equivalents and restricted cash at beginning of period | |||||
| Cash, cash equivalents and restricted cash at end of period | |||||
| Supplemental cash flow information: | |||||
| Cash paid for taxes | |||||
| Supplemental disclosure and noncash investing and financing information: | |||||
| Purchases of property and equipment included in accounts payable and accrued expenses | |||||
| Asset acquired in finance lease | |||||
| Reconciliation of cash, cash equivalents and restricted cash: | |||||
| Cash and cash equivalents | |||||
| Restricted cash (current and non-current) | |||||
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