$FOLD
AMICUS THERAPEUTICS, INC. Stock $fold

$fold Overview Financials Valuation SEC Filings Company Website

2014 Q1 Form 10-K Financial Statement

#000104746914001702 Filed on March 03, 2014

Income Statement

Concept	2014 Q1	2013 Q4	2013
Revenue	$456.0K	$320.0K	$363.0K
YoY Change			-98.03%
Cost Of Revenue
YoY Change
Gross Profit
YoY Change
Gross Profit Margin
Selling, General & Admin	$5.180M	$4.610M	$18.40M
YoY Change	7.47%	3.36%	-5.15%
% of Gross Profit
Research & Development	$9.992M	$9.120M	$41.94M
YoY Change	-16.66%	-17.47%	-16.57%
% of Gross Profit
Depreciation & Amortization	$410.0K	$400.0K	$1.720M
YoY Change	-6.82%	-6.98%	0.58%
% of Gross Profit
Operating Expenses	$16.08M	$14.12M	$64.54M
YoY Change	-6.81%	-11.31%	-9.53%
Operating Profit	-$15.62M		-$64.18M
YoY Change	-9.45%		21.25%
Interest Expense	$355.0K	$40.00K	$46.00K
YoY Change	3450.0%	-98.5%	-48.31%
% of Operating Profit
Other Income/Expense, Net	-$9.000K	$0.00	$0.00
YoY Change			-100.0%
Pretax Income	-$15.94M	-$15.75M	-$63.15M
YoY Change	-8.68%	18.78%	21.36%
Income Tax	$0.00	-$3.510M	-$3.512M
% Of Pretax Income
Net Earnings	-$15.94M	-$12.24M	-$59.63M
YoY Change	-8.68%	22.19%	22.24%
Net Earnings / Revenue	-3496.27%	-3824.06%	-16427.82%
Basic Earnings Per Share
Diluted Earnings Per Share	-$247.7K	-$217.9K	-$1.162M
COMMON SHARES
Basic Shares Outstanding	62.26M shares	49.63M shares
Diluted Shares Outstanding

Balance Sheet

Concept	2014 Q1	2013 Q4	2013
SHORT-TERM ASSETS
Cash & Short-Term Investments	$71.70M	$82.00M	$82.00M
YoY Change	-15.45%	-17.26%	-17.26%
Cash & Equivalents	$27.53M	$43.64M	$43.60M
Short-Term Investments	$44.10M	$38.40M	$38.40M
Other Short-Term Assets	$1.758M	$5.195M	$5.200M
YoY Change	0.29%	128.85%	126.09%
Inventory
Prepaid Expenses
Receivables	$0.00	$1.100M	$1.100M
Other Receivables	$0.00	$0.00	$0.00
Total Short-Term Assets	$73.45M	$88.28M	$88.30M
YoY Change	-16.36%	-15.62%	-15.58%
LONG-TERM ASSETS
Property, Plant & Equipment	$3.748M	$4.120M	$4.100M
YoY Change	-24.47%	-18.08%	-18.0%
Goodwill	$11.61M	$11.61M
YoY Change
Intangibles	$23.00M	$23.00M
YoY Change
Long-Term Investments		$0.00	$0.00
YoY Change
Other Assets	$546.0K	$552.0K	$600.0K
YoY Change	23.53%	24.89%	50.0%
Total Long-Term Assets	$38.91M	$39.29M	$39.30M
YoY Change	619.97%	618.06%	614.55%
TOTAL ASSETS
Total Short-Term Assets	$73.45M	$88.28M	$88.30M
Total Long-Term Assets	$38.91M	$39.29M	$39.30M
Total Assets	$112.4M	$127.6M	$127.6M
YoY Change	20.53%	15.87%	15.89%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable	$9.200M	$2.146M	$2.100M
YoY Change	43.75%	1.47%	0.0%
Accrued Expenses			$8.000M
YoY Change			19.4%
Deferred Revenue
YoY Change
Short-Term Debt	$0.00	$0.00	$0.00
YoY Change
Long-Term Debt Due	$200.0K	$300.0K	$300.0K
YoY Change	-50.0%	-25.0%	-25.0%
Total Short-Term Liabilities	$9.366M	$10.46M	$10.50M
YoY Change	17.15%	13.18%	14.13%
LONG-TERM LIABILITIES
Long-Term Debt	$14.20M	$14.20M	$14.20M
YoY Change	7000.0%	4633.33%	4633.33%
Other Long-Term Liabilities	$723.0K	$714.0K	$48.00M
YoY Change	-97.72%	-97.72%	53.35%
Total Long-Term Liabilities	$723.0K	$714.0K	$62.20M
YoY Change	-97.73%	-97.74%	96.84%
TOTAL LIABILITIES
Total Short-Term Liabilities	$9.366M	$10.46M	$10.50M
Total Long-Term Liabilities	$723.0K	$714.0K	$62.20M
Total Liabilities	$10.09M	$11.18M	$81.80M
YoY Change	-74.71%	-72.68%	100.0%
SHAREHOLDERS EQUITY
Retained Earnings	-$394.5M	-$378.5M
YoY Change	17.28%	18.7%
Common Stock	$425.5M	$424.3M
YoY Change	9.21%	9.32%
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity	$31.08M	$45.75M	$45.80M
YoY Change
Total Liabilities & Shareholders Equity	$112.4M	$127.6M	$127.6M
YoY Change	20.53%	15.87%	15.89%

Cashflow Statement

Concept	2014 Q1	2013 Q4	2013
OPERATING ACTIVITIES
Net Income	-$15.94M	-$12.24M	-$59.63M
YoY Change	-8.68%	22.19%	22.24%
Depreciation, Depletion And Amortization	$410.0K	$400.0K	$1.720M
YoY Change	-6.82%	-6.98%	0.58%
Cash From Operating Activities	-$10.22M	-$8.120M	-$45.79M
YoY Change	-26.47%	10.18%	35.71%
INVESTING ACTIVITIES
Capital Expenditures	$40.00K	-$50.00K	$695.0K
YoY Change	-89.25%	-66.67%	-83.93%
Acquisitions
YoY Change
Other Investing Activities	-$5.760M	-$7.910M	$26.78M
YoY Change	-180.67%	-147.17%	-176.27%
Cash From Investing Activities	-$5.800M	-$7.970M	$26.08M
YoY Change	-185.67%	-147.98%	-166.14%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net			$15.00M
YoY Change			-81.3%
Debt Paid & Issued, Net
YoY Change
Cash From Financing Activities	-90.00K	29.68M	29.38M
YoY Change	-10.0%	6352.17%	-63.94%
NET CHANGE
Cash From Operating Activities	-10.22M	-8.120M	-45.79M
Cash From Investing Activities	-5.800M	-7.970M	26.08M
Cash From Financing Activities	-90.00K	29.68M	29.38M
Net Change In Cash	-16.11M	13.59M	9.670M
YoY Change	122.82%	40.1%	16.37%
FREE CASH FLOW
Cash From Operating Activities	-$10.22M	-$8.120M	-$45.79M
Capital Expenditures	$40.00K	-$50.00K	$695.0K
Free Cash Flow	-$10.26M	-$8.070M	-$46.49M
YoY Change	-28.11%	11.77%	22.12%

Facts In Submission

Frame	Concept Type	Concept / XBRL Key	Value	Unit
	us-gaap	Issuance Of Stock And Warrants For Services Or Claims IssuanceOfStockAndWarrantsForServicesOrClaims	853000	USD
CY2013Q4	us-gaap	Deferred Tax Assets Tax Credit Carryforwards Research DeferredTaxAssetsTaxCreditCarryforwardsResearch	13680000	USD
CY2013Q4	us-gaap	Deferred Tax Assets Operating Loss Carryforwards DeferredTaxAssetsOperatingLossCarryforwards	79984000	USD
CY2013	us-gaap	Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Settlements FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements	-900000	USD
CY2013	us-gaap	Defined Contribution Plan Maximum Annual Contributions Per Employee Percent DefinedContributionPlanMaximumAnnualContributionsPerEmployeePercent	0.05	pure
CY2012	us-gaap	Defined Contribution Plan Cost Recognized DefinedContributionPlanCostRecognized	700000	USD
CY2013	us-gaap	Defined Contribution Plan Cost Recognized DefinedContributionPlanCostRecognized	700000	USD
CY2011	us-gaap	Defined Contribution Plan Cost Recognized DefinedContributionPlanCostRecognized	600000	USD
CY2011Q4	us-gaap	Area Of Real Estate Property AreaOfRealEstateProperty	73646
CY2011	us-gaap	Lessee Leasing Arrangements Operating Leases Term Of Contract LesseeLeasingArrangementsOperatingLeasesTermOfContract	P7Y
CY2011Q4	fold	Operating Leases Option To Extend Number Of Lease Term OperatingLeasesOptionToExtendNumberOfLeaseTerm	2	item
CY2011	us-gaap	Lessee Leasing Arrangements Operating Leases Renewal Term LesseeLeasingArrangementsOperatingLeasesRenewalTerm	P5Y
CY2013Q4	us-gaap	Operating Leases Future Minimum Payments Due Current OperatingLeasesFutureMinimumPaymentsDueCurrent	1930000	USD
CY2013Q4	us-gaap	Operating Leases Future Minimum Payments Due In Two Years OperatingLeasesFutureMinimumPaymentsDueInTwoYears	2033000	USD
CY2013Q4	us-gaap	Operating Leases Future Minimum Payments Due In Three Years OperatingLeasesFutureMinimumPaymentsDueInThreeYears	2039000	USD
CY2013Q4	us-gaap	Operating Leases Future Minimum Payments Due In Four Years OperatingLeasesFutureMinimumPaymentsDueInFourYears	1769000	USD
CY2013Q4	fold	Operating Leases Future Minimum Payments Due In Five Years And Thereafter OperatingLeasesFutureMinimumPaymentsDueInFiveYearsAndThereafter	2074000	USD
CY2013Q4	us-gaap	Operating Leases Future Minimum Payments Due OperatingLeasesFutureMinimumPaymentsDue	9845000	USD
CY2011	us-gaap	Operating Leases Rent Expense Net OperatingLeasesRentExpenseNet	2300000	USD
CY2012	us-gaap	Operating Leases Rent Expense Net OperatingLeasesRentExpenseNet	2600000	USD
CY2013	us-gaap	Operating Leases Rent Expense Net OperatingLeasesRentExpenseNet	2600000	USD
CY2013	dei	Entity Registrant Name EntityRegistrantName	AMICUS THERAPEUTICS INC
CY2013	dei	Entity Central Index Key EntityCentralIndexKey	0001178879
CY2013	dei	Document Type DocumentType	10-K
CY2013	dei	Amendment Flag AmendmentFlag	false
CY2013	dei	Entity Current Reporting Status EntityCurrentReportingStatus	Yes
CY2013	dei	Entity Filer Category EntityFilerCategory	Accelerated Filer
CY2014Q1	dei	Entity Common Stock Shares Outstanding EntityCommonStockSharesOutstanding	62263325	shares
CY2013	dei	Document Fiscal Year Focus DocumentFiscalYearFocus	2013
CY2013	dei	Document Fiscal Period Focus DocumentFiscalPeriodFocus	FY
CY2013	dei	Document Period End Date DocumentPeriodEndDate	2013-12-31
CY2013	dei	Current Fiscal Year End Date CurrentFiscalYearEndDate	--12-31
CY2013	dei	Entity Well Known Seasoned Issuer EntityWellKnownSeasonedIssuer	No
CY2013	dei	Entity Voluntary Filers EntityVoluntaryFilers	No
CY2013Q2	dei	Entity Public Float EntityPublicFloat	53244333	USD
	us-gaap	Increase Decrease In Prepaid Deferred Expense And Other Assets IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets	5519000	USD
CY2013Q4	us-gaap	Retained Earnings Accumulated Deficit RetainedEarningsAccumulatedDeficit	-378522000	USD
CY2012Q4	us-gaap	Available For Sale Securities AvailableForSaleSecurities	65151000	USD
CY2013Q4	us-gaap	Available For Sale Securities AvailableForSaleSecurities	38360000	USD
CY2004	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	-9000	USD
CY2012	us-gaap	Available For Sale Securities Gross Realized Gain Loss Net AvailableForSaleSecuritiesGrossRealizedGainLossNet	0	USD
CY2013	us-gaap	Available For Sale Securities Gross Realized Gain Loss Net AvailableForSaleSecuritiesGrossRealizedGainLossNet	0	USD
CY2012Q4	us-gaap	Available For Sale Securities Continuous Unrealized Loss Position Less Than Twelve Months Fair Value AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue	33100000	USD
CY2010Q1	us-gaap	Stock Issued During Period Shares New Issues StockIssuedDuringPeriodSharesNewIssues	4950000	shares
CY2010Q1	us-gaap	Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights	1900000	shares
CY2010Q1	fold	Proceeds From Issuance Of Common Stock And Warrants ProceedsFromIssuanceOfCommonStockAndWarrants	17100000	USD
CY2010Q1	fold	Warrant Term WarrantTerm	P4Y
CY2012Q1	us-gaap	Stock Issued During Period Shares New Issues StockIssuedDuringPeriodSharesNewIssues	11500000	shares
CY2012Q1	us-gaap	Proceeds From Issuance Of Common Stock ProceedsFromIssuanceOfCommonStock	62000000	USD
CY2012Q4	us-gaap	Cash Cash Equivalents And Short Term Investments CashCashEquivalentsAndShortTermInvestments	99108000	USD
CY2013Q4	us-gaap	Cash Cash Equivalents And Short Term Investments CashCashEquivalentsAndShortTermInvestments	81999000	USD
CY2012Q4	fold	Cash Cash Equivalents And Short Term Investments Fair Value Disclosure CashCashEquivalentsAndShortTermInvestmentsFairValueDisclosure	99122000	USD
CY2013Q4	fold	Cash Cash Equivalents And Short Term Investments Fair Value Disclosure CashCashEquivalentsAndShortTermInvestmentsFairValueDisclosure	82000000	USD
CY2012Q4	fold	Available For Sale Securities Accumulated Gross Unrealized Gain Before Tax AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax	-25000	USD
CY2013Q4	fold	Available For Sale Securities Accumulated Gross Unrealized Gain Before Tax AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax	-7000	USD
CY2012Q4	fold	Available For Sale Securities Accumulated Gross Unrealized Loss Before Tax AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax	-11000	USD
CY2013Q4	fold	Available For Sale Securities Accumulated Gross Unrealized Loss Before Tax AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax	-6000	USD
CY2012Q4	us-gaap	Available For Sale Securities Amortized Cost AvailableForSaleSecuritiesAmortizedCost	65137000	USD
CY2013Q4	us-gaap	Available For Sale Securities Continuous Unrealized Loss Position Less Than Twelve Months Fair Value AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue	23600000	USD
CY2012Q4	us-gaap	Property Plant And Equipment Gross PropertyPlantAndEquipmentGross	13530000	USD
CY2013	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	-13000	USD
CY2013	us-gaap	Use Of Estimates UseOfEstimates	<div style="font-size:10.0pt;font-family:Times New Roman;"> <ul> <li style="list-style: none;"> <p style="FONT-FAMILY: times;"><font size="2"><b><i>Use of Estimates</i></b></font></p></li></ul> <p style="FONT-FAMILY: times;"><font size="2">        The preparation of financial statements in conformity with U.S. GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities, the disclosure of contingent assets and liabilities at the date of the financial statements, and the reported amounts of revenues and expenses during the reporting periods. Actual results could differ from those estimates.</font></p> </div>
CY2012	us-gaap	Interest Paid InterestPaid	84000	USD
	us-gaap	Interest Paid InterestPaid	2147000	USD
CY2010Q4	us-gaap	Cash And Cash Equivalents At Carrying Value CashAndCashEquivalentsAtCarryingValue	29572000	USD
CY2013Q4	fold	Share Based Compensation Number Of Plans ShareBasedCompensationNumberOfPlans	3	item
CY2012	us-gaap	Net Income Loss Available To Common Stockholders Basic NetIncomeLossAvailableToCommonStockholdersBasic	-48785000	USD
CY2011	us-gaap	Net Income Loss Available To Common Stockholders Basic NetIncomeLossAvailableToCommonStockholdersBasic	-44412000	USD
CY2013	us-gaap	Net Income Loss Available To Common Stockholders Basic NetIncomeLossAvailableToCommonStockholdersBasic	-59633000	USD
CY2013	us-gaap	Concentration Risk Credit Risk ConcentrationRiskCreditRisk	<div style="font-size:10.0pt;font-family:Times New Roman;"> <ul> <li style="list-style: none;"> <p style="FONT-FAMILY: times;"><font size="2"><b><i>Concentration of Credit Risk</i></b></font></p></li></ul> <p style="FONT-FAMILY: times;"><font size="2">        The Company's financial instruments that are exposed to concentration of credit risk consist primarily of cash and cash equivalents and marketable securities. The Company maintains its cash and cash equivalents in bank accounts, which, at times, exceed federally insured limits. The Company invests its marketable securities in high-quality commercial financial instruments. The Company has not recognized any losses from credit risks on such accounts during any of the periods presented. The Company believes it is not exposed to significant credit risk on cash and cash equivalents or its marketable securities.</font></p> </div>
CY2012	us-gaap	Weighted Average Number Of Share Outstanding Basic And Diluted WeightedAverageNumberOfShareOutstandingBasicAndDiluted	45565217	shares
CY2013	us-gaap	Weighted Average Number Of Share Outstanding Basic And Diluted WeightedAverageNumberOfShareOutstandingBasicAndDiluted	51286059	shares
CY2011	us-gaap	Weighted Average Number Of Share Outstanding Basic And Diluted WeightedAverageNumberOfShareOutstandingBasicAndDiluted	34569642	shares
CY2010Q1	fold	Exercise Period Of Warrant On Or After Issued ExercisePeriodOfWarrantOnOrAfterIssued	P6M
CY2013	us-gaap	Number Of Operating Segments NumberOfOperatingSegments	1	item
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CY2012Q4	us-gaap	Cash And Cash Equivalents At Carrying Value CashAndCashEquivalentsAtCarryingValue	33971000	USD
CY2013Q4	us-gaap	Available For Sale Securities Amortized Cost AvailableForSaleSecuritiesAmortizedCost	38359000	USD
CY2013Q4	us-gaap	Cash And Cash Equivalents Fair Value Disclosure CashAndCashEquivalentsFairValueDisclosure	43640000	USD
CY2013Q4	us-gaap	Property Plant And Equipment Gross PropertyPlantAndEquipmentGross	14093000	USD
CY2012Q4	us-gaap	Accumulated Depreciation Depletion And Amortization Property Plant And Equipment AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment	8501000	USD
CY2013Q4	us-gaap	Accumulated Depreciation Depletion And Amortization Property Plant And Equipment AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment	9973000	USD
CY2012Q4	us-gaap	Property Plant And Equipment Net PropertyPlantAndEquipmentNet	5029000	USD
CY2013Q4	us-gaap	Property Plant And Equipment Net PropertyPlantAndEquipmentNet	4120000	USD
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CY2013	us-gaap	Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Issues FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityIssues	10600000	USD
CY2012Q4	us-gaap	Employee Related Liabilities Current EmployeeRelatedLiabilitiesCurrent	4229000	USD
CY2013Q4	us-gaap	Employee Related Liabilities Current EmployeeRelatedLiabilitiesCurrent	4781000	USD
CY2012Q4	fold	Accrued Facility Costs Current AccruedFacilityCostsCurrent	167000	USD
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CY2012Q4	us-gaap	Other Accrued Liabilities Current OtherAccruedLiabilitiesCurrent	182000	USD
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CY2013Q4	us-gaap	Accounts Payable Current AccountsPayableCurrent	2146000	USD
CY2012Q4	us-gaap	Accrued Professional Fees Current AccruedProfessionalFeesCurrent	409000	USD
CY2013Q4	us-gaap	Accrued Professional Fees Current AccruedProfessionalFeesCurrent	498000	USD
CY2012Q4	fold	Accrued Contract Manufacturing And Contract Research Costs Current AccruedContractManufacturingAndContractResearchCostsCurrent	1743000	USD
CY2013Q4	fold	Accrued Contract Manufacturing And Contract Research Costs Current AccruedContractManufacturingAndContractResearchCostsCurrent	1499000	USD
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CY2011	us-gaap	Allocated Share Based Compensation Expense AllocatedShareBasedCompensationExpense	8679000	USD
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CY2013	us-gaap	Allocated Share Based Compensation Expense AllocatedShareBasedCompensationExpense	6177000	USD
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CY2012Q4	us-gaap	Other Assets Current OtherAssetsCurrent	2270000	USD
CY2012Q4	us-gaap	Assets Current AssetsCurrent	104617000	USD
CY2012Q4	us-gaap	Other Assets Noncurrent OtherAssetsNoncurrent	442000	USD
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CY2012	us-gaap	Stock And Warrants Issued During Period Value Preferred Stock And Warrants StockAndWarrantsIssuedDuringPeriodValuePreferredStockAndWarrants	386000	USD
CY2012Q4	us-gaap	Secured Debt Current SecuredDebtCurrent	398000	USD
CY2012Q4	us-gaap	Liabilities Current LiabilitiesCurrent	9243000	USD
CY2012Q4	us-gaap	Common Stock Value CommonStockValue	556000	USD
CY2012Q4	us-gaap	Secured Long Term Debt SecuredLongTermDebt	299000	USD
CY2012Q4	us-gaap	Additional Paid In Capital Common Stock AdditionalPaidInCapitalCommonStock	387539000	USD
CY2012Q4	us-gaap	Accumulated Other Comprehensive Income Loss Net Of Tax AccumulatedOtherComprehensiveIncomeLossNetOfTax	14000	USD
CY2012Q4	us-gaap	Retained Earnings Accumulated Deficit RetainedEarningsAccumulatedDeficit	-318889000	USD
CY2012Q4	us-gaap	Stockholders Equity StockholdersEquity	69220000	USD
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CY2011	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	-3629000	USD
CY2012	us-gaap	Other Comprehensive Income Loss Before Tax Portion Attributable To Parent OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent	10000	USD
CY2012Q4	us-gaap	Liabilities And Stockholders Equity LiabilitiesAndStockholdersEquity	110088000	USD
CY2013Q4	us-gaap	Assets Assets	127563000	USD
CY2013Q4	us-gaap	Assets Current AssetsCurrent	88278000	USD
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CY2013Q4	us-gaap	Liabilities And Stockholders Equity LiabilitiesAndStockholdersEquity	127563000	USD
CY2013Q4	us-gaap	Stockholders Equity StockholdersEquity	45751000	USD
CY2013Q4	us-gaap	Commitments And Contingencies CommitmentsAndContingencies		USD
CY2012Q4	us-gaap	Commitments And Contingencies CommitmentsAndContingencies		USD
CY2012Q4	us-gaap	Common Stock Par Or Stated Value Per Share CommonStockParOrStatedValuePerShare	0.01
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CY2012Q4	us-gaap	Common Stock Shares Authorized CommonStockSharesAuthorized	125000000	shares
CY2012Q4	us-gaap	Common Stock Shares Issued CommonStockSharesIssued	49631672	shares
CY2012Q4	us-gaap	Common Stock Shares Outstanding CommonStockSharesOutstanding	49631672	shares
CY2013Q4	us-gaap	Common Stock Shares Issued CommonStockSharesIssued	61975416	shares
CY2013Q4	us-gaap	Common Stock Shares Outstanding CommonStockSharesOutstanding	61975416	shares
CY2011	fold	Research Revenue ResearchRevenue	14794000	USD
CY2012	fold	Research Revenue ResearchRevenue	11591000	USD
CY2011	fold	Collaboration Revenue CollaborationRevenue	6640000	USD
CY2012	fold	Collaboration Revenue CollaborationRevenue	6820000	USD
CY2011	us-gaap	Sales Revenue Net SalesRevenueNet	21434000	USD
CY2012	us-gaap	Sales Revenue Net SalesRevenueNet	18411000	USD
CY2011	us-gaap	Research And Development Expense Excluding Acquired In Process Cost ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost	50856000	USD
CY2012	us-gaap	Research And Development Expense Excluding Acquired In Process Cost ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost	50273000	USD
CY2011	us-gaap	General And Administrative Expense GeneralAndAdministrativeExpense	19880000	USD
CY2012	us-gaap	General And Administrative Expense GeneralAndAdministrativeExpense	19364000	USD
CY2011	us-gaap	Depreciation And Amortization DepreciationAndAmortization	1585000	USD
CY2012	us-gaap	Depreciation And Amortization DepreciationAndAmortization	1705000	USD
CY2011	us-gaap	Operating Expenses OperatingExpenses	72321000	USD
CY2012	us-gaap	Operating Expenses OperatingExpenses	71342000	USD
CY2011	us-gaap	Operating Income Loss OperatingIncomeLoss	-50887000	USD
CY2012	us-gaap	Operating Income Loss OperatingIncomeLoss	-52931000	USD
CY2011	us-gaap	Investment Income Interest InvestmentIncomeInterest	160000	USD
CY2012	us-gaap	Investment Income Interest InvestmentIncomeInterest	316000	USD
CY2011	us-gaap	Interest Expense InterestExpense	148000	USD
CY2012	us-gaap	Interest Expense InterestExpense	89000	USD
CY2011	us-gaap	Fair Value Adjustment Of Warrants FairValueAdjustmentOfWarrants	-2764000	USD
CY2012	us-gaap	Fair Value Adjustment Of Warrants FairValueAdjustmentOfWarrants	-653000	USD
CY2011	us-gaap	Other Nonoperating Income Expense OtherNonoperatingIncomeExpense	70000	USD
CY2012	us-gaap	Other Nonoperating Income Expense OtherNonoperatingIncomeExpense	21000	USD
CY2011	us-gaap	Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments	-48041000	USD
CY2012	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	-3245000	USD
CY2011	us-gaap	Net Income Loss NetIncomeLoss	-44412000	USD
CY2012	us-gaap	Net Income Loss NetIncomeLoss	-48785000	USD
CY2011	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-1.28
CY2012	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-1.07
	us-gaap	Sales Revenue Net SalesRevenueNet	122238000	USD
CY2011	us-gaap	Other Comprehensive Income Loss Before Tax Portion Attributable To Parent OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent	32000	USD
CY2013	us-gaap	Sales Revenue Net SalesRevenueNet	363000	USD
CY2013	us-gaap	Operating Expenses OperatingExpenses	64544000	USD
CY2013	us-gaap	Operating Income Loss OperatingIncomeLoss	-64181000	USD
CY2013	us-gaap	Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments	-63145000	USD
CY2013	us-gaap	Net Income Loss NetIncomeLoss	-59633000	USD
CY2013	us-gaap	Other Comprehensive Income Loss Before Tax Portion Attributable To Parent OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent	-13000	USD
	us-gaap	Operating Expenses OperatingExpenses	527788000	USD
	us-gaap	Operating Income Loss OperatingIncomeLoss	-405550000	USD
CY2011Q4	us-gaap	Cash And Cash Equivalents At Carrying Value CashAndCashEquivalentsAtCarryingValue	25668000	USD
CY2013Q4	us-gaap	Fair Value Assets Level1 To Level2 Transfers Amount FairValueAssetsLevel1ToLevel2TransfersAmount	0	USD
CY2011	us-gaap	Comprehensive Income Net Of Tax ComprehensiveIncomeNetOfTax	-44380000	USD
CY2012	us-gaap	Comprehensive Income Net Of Tax ComprehensiveIncomeNetOfTax	-48775000	USD
CY2013	us-gaap	Comprehensive Income Net Of Tax ComprehensiveIncomeNetOfTax	-59646000	USD
	us-gaap	Comprehensive Income Net Of Tax ComprehensiveIncomeNetOfTax	-378521000	USD
	us-gaap	Paid In Kind Interest PaidInKindInterest	525000	USD
	us-gaap	Other Amortization Of Deferred Charges OtherAmortizationOfDeferredCharges	522000	USD
CY2011	us-gaap	Share Based Compensation ShareBasedCompensation	8679000	USD
	us-gaap	Proceeds From Convertible Debt ProceedsFromConvertibleDebt	5000000	USD
CY2011	us-gaap	Repayments Of Long Term Capital Lease Obligations RepaymentsOfLongTermCapitalLeaseObligations	40000	USD
CY2012	us-gaap	Repayments Of Secured Debt RepaymentsOfSecuredDebt	1342000	USD
	us-gaap	Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments	-390742000	USD
	us-gaap	Net Income Loss NetIncomeLoss	-378522000	USD
	us-gaap	Net Income Loss Available To Common Stockholders Basic NetIncomeLossAvailableToCommonStockholdersBasic	-398748000	USD
	us-gaap	Impairment Of Leasehold ImpairmentOfLeasehold	1030000	USD
	us-gaap	Restructuring Charges RestructuringCharges	3510000	USD
	us-gaap	Research And Development In Process ResearchAndDevelopmentInProcess	418000	USD
	fold	Deemed Dividend DeemedDividend	19424000	USD
	us-gaap	Temporary Equity Accretion Of Dividends TemporaryEquityAccretionOfDividends	-802000	USD
CY2013	us-gaap	Other Comprehensive Income Loss Tax Portion Attributable To Parent1 OtherComprehensiveIncomeLossTaxPortionAttributableToParent1	0	USD
CY2011	us-gaap	Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent	32000	USD
CY2012	us-gaap	Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent	10000	USD
CY2013	us-gaap	Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent	-13000	USD
CY2012	us-gaap	Share Based Compensation ShareBasedCompensation	6191000	USD
CY2012	us-gaap	Gain Loss On Sale Of Property Plant Equipment GainLossOnSaleOfPropertyPlantEquipment	-28000	USD
	fold	Stock Based License Payments StockBasedLicensePayments	1220000	USD
	us-gaap	Adjustments To Additional Paid In Capital Convertible Debt With Conversion Feature AdjustmentsToAdditionalPaidInCapitalConvertibleDebtWithConversionFeature	-135000	USD
CY2011	us-gaap	Increase Decrease In Due From Related Parties Current IncreaseDecreaseInDueFromRelatedPartiesCurrent	5043000	USD
CY2012	us-gaap	Increase Decrease In Due From Related Parties Current IncreaseDecreaseInDueFromRelatedPartiesCurrent	-1818000	USD
CY2011	us-gaap	Increase Decrease In Prepaid Deferred Expense And Other Assets IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets	3667000	USD
CY2012	us-gaap	Increase Decrease In Prepaid Deferred Expense And Other Assets IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets	-3633000	USD
CY2011	us-gaap	Increase Decrease In Other Operating Assets IncreaseDecreaseInOtherOperatingAssets	442000	USD
CY2012	us-gaap	Increase Decrease In Other Operating Assets IncreaseDecreaseInOtherOperatingAssets	-267000	USD
CY2011	us-gaap	Increase Decrease In Accounts Payable And Accrued Liabilities IncreaseDecreaseInAccountsPayableAndAccruedLiabilities	1418000	USD
CY2012	us-gaap	Increase Decrease In Accounts Payable And Accrued Liabilities IncreaseDecreaseInAccountsPayableAndAccruedLiabilities	-863000	USD
CY2011	us-gaap	Increase Decrease In Other Noncurrent Liabilities IncreaseDecreaseInOtherNoncurrentLiabilities	-4776000	USD
CY2012	us-gaap	Increase Decrease In Other Noncurrent Liabilities IncreaseDecreaseInOtherNoncurrentLiabilities	2915000	USD
CY2011	us-gaap	Net Cash Provided By Used In Operating Activities Continuing Operations NetCashProvidedByUsedInOperatingActivitiesContinuingOperations	-49422000	USD
CY2012	us-gaap	Net Cash Provided By Used In Operating Activities Continuing Operations NetCashProvidedByUsedInOperatingActivitiesContinuingOperations	-33744000	USD
CY2013	us-gaap	Net Cash Provided By Used In Operating Activities Continuing Operations NetCashProvidedByUsedInOperatingActivitiesContinuingOperations	-45794000	USD
	us-gaap	Net Cash Provided By Used In Operating Activities Continuing Operations NetCashProvidedByUsedInOperatingActivitiesContinuingOperations	-274146000	USD
CY2011	us-gaap	Proceeds From Sale And Maturity Of Available For Sale Securities ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities	98474000	USD
CY2012	us-gaap	Proceeds From Sale And Maturity Of Available For Sale Securities ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities	83352000	USD
CY2011	us-gaap	Payments To Acquire Available For Sale Securities PaymentsToAcquireAvailableForSaleSecurities	50602000	USD
CY2012	us-gaap	Payments To Acquire Available For Sale Securities PaymentsToAcquireAvailableForSaleSecurities	118459000	USD
CY2011	us-gaap	Payments To Acquire Property Plant And Equipment PaymentsToAcquirePropertyPlantAndEquipment	1420000	USD
CY2012	us-gaap	Payments To Acquire Property Plant And Equipment PaymentsToAcquirePropertyPlantAndEquipment	4324000	USD
CY2011	us-gaap	Net Cash Provided By Used In Investing Activities Continuing Operations NetCashProvidedByUsedInInvestingActivitiesContinuingOperations	46452000	USD
CY2012	us-gaap	Net Cash Provided By Used In Investing Activities Continuing Operations NetCashProvidedByUsedInInvestingActivitiesContinuingOperations	-39431000	USD
CY2013	us-gaap	Net Cash Provided By Used In Investing Activities Continuing Operations NetCashProvidedByUsedInInvestingActivitiesContinuingOperations	26083000	USD
	us-gaap	Net Cash Provided By Used In Investing Activities Continuing Operations NetCashProvidedByUsedInInvestingActivitiesContinuingOperations	-57383000	USD
	us-gaap	Proceeds From Issuance Of Preferred Stock And Preference Stock ProceedsFromIssuanceOfPreferredStockAndPreferenceStock	143022000	USD
CY2012	us-gaap	Proceeds From Issuance Of Common Stock ProceedsFromIssuanceOfCommonStock	80195000	USD
CY2011	us-gaap	Proceeds From Stock Options Exercised ProceedsFromStockOptionsExercised	359000	USD
CY2012	us-gaap	Proceeds From Stock Options Exercised ProceedsFromStockOptionsExercised	1630000	USD
	us-gaap	Proceeds From Warrant Exercises ProceedsFromWarrantExercises	264000	USD
	us-gaap	Proceeds From Issuance Of Other Long Term Debt ProceedsFromIssuanceOfOtherLongTermDebt	5611000	USD
CY2012	us-gaap	Proceeds From Issuance Of Secured Debt ProceedsFromIssuanceOfSecuredDebt	995000	USD
CY2011	us-gaap	Net Cash Provided By Used In Financing Activities Continuing Operations NetCashProvidedByUsedInFinancingActivitiesContinuingOperations	-934000	USD
CY2012	fold	Income Tax Expenses Benefit From Sale Of Net Operating Losses And Research And Development Credits IncomeTaxExpensesBenefitFromSaleOfNetOperatingLossesAndResearchAndDevelopmentCredits	3200000	USD
CY2013	fold	Income Tax Expenses Benefit From Sale Of Net Operating Losses And Research And Development Credits IncomeTaxExpensesBenefitFromSaleOfNetOperatingLossesAndResearchAndDevelopmentCredits	3500000	USD
CY2013Q4	us-gaap	Fair Value Assets Level2 To Level1 Transfers Amount FairValueAssetsLevel2ToLevel1TransfersAmount	0	USD
CY2013	us-gaap	Proceeds From Issuance Of Warrants ProceedsFromIssuanceOfWarrants	1046000	USD
CY2013	us-gaap	Interest Paid InterestPaid	30000	USD
CY2011	us-gaap	Interest Paid InterestPaid	149000	USD
CY2012	us-gaap	Net Cash Provided By Used In Financing Activities Continuing Operations NetCashProvidedByUsedInFinancingActivitiesContinuingOperations	81478000	USD
CY2011	us-gaap	Net Cash Provided By Used In Continuing Operations NetCashProvidedByUsedInContinuingOperations	-3904000	USD
CY2012	us-gaap	Net Cash Provided By Used In Continuing Operations NetCashProvidedByUsedInContinuingOperations	8303000	USD
CY2013	us-gaap	Net Cash Provided By Used In Financing Activities Continuing Operations NetCashProvidedByUsedInFinancingActivitiesContinuingOperations	29380000	USD
CY2013	us-gaap	Net Cash Provided By Used In Continuing Operations NetCashProvidedByUsedInContinuingOperations	9669000	USD
	us-gaap	Net Cash Provided By Used In Financing Activities Continuing Operations NetCashProvidedByUsedInFinancingActivitiesContinuingOperations	375169000	USD
	us-gaap	Net Cash Provided By Used In Continuing Operations NetCashProvidedByUsedInContinuingOperations	43640000	USD
	us-gaap	Stock And Warrants Issued During Period Value Preferred Stock And Warrants StockAndWarrantsIssuedDuringPeriodValuePreferredStockAndWarrants	386000	USD
	fold	Conversion Of Notes Payable To Preferred Stock ConversionOfNotesPayableToPreferredStock	5000000	USD
	us-gaap	Conversion Of Stock Amount Converted1 ConversionOfStockAmountConverted1	148951000	USD
CY2011	us-gaap	Repayments Of Secured Debt RepaymentsOfSecuredDebt	1253000	USD
	fold	Accretion Of Redeemable Convertible Preferred Stock AccretionOfRedeemableConvertiblePreferredStock	802000	USD
	fold	Beneficial Conversion Feature Related To Issuance Of Series C Redeemable Convertible Preferred Stock BeneficialConversionFeatureRelatedToIssuanceOfSeriesCRedeemableConvertiblePreferredStock	19424000	USD
CY2013	fold	Fair Value Inputs Number Of Inputs Used In Fair Value Classification FairValueInputsNumberOfInputsUsedInFairValueClassification	6	item
CY2012	us-gaap	Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Period Increase Decrease FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPeriodIncreaseDecrease	-700000	USD
CY2012	us-gaap	Fair Value Assumptions Expected Volatility Rate FairValueAssumptionsExpectedVolatilityRate	0.932	pure
CY2013	us-gaap	Fair Value Assumptions Expected Volatility Rate FairValueAssumptionsExpectedVolatilityRate	0.459	pure
CY2012	us-gaap	Fair Value Assumptions Risk Free Interest Rate FairValueAssumptionsRiskFreeInterestRate	0.0017	pure
CY2013	us-gaap	Fair Value Assumptions Risk Free Interest Rate FairValueAssumptionsRiskFreeInterestRate	0.0007	pure
CY2012	us-gaap	Fair Value Assumptions Expected Term FairValueAssumptionsExpectedTerm	P1Y2M1D
CY2013	us-gaap	Fair Value Assumptions Expected Term FairValueAssumptionsExpectedTerm	P2M1D
CY2012	us-gaap	Fair Value Assumptions Expected Dividend Rate FairValueAssumptionsExpectedDividendRate	0.00	pure
CY2013	us-gaap	Fair Value Assumptions Expected Dividend Rate FairValueAssumptionsExpectedDividendRate	0.00	pure
CY2012	us-gaap	Effective Income Tax Rate Reconciliation Other Adjustments EffectiveIncomeTaxRateReconciliationOtherAdjustments	0.01	pure
CY2011	us-gaap	Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance	0.34	pure
CY2012	us-gaap	Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance	0.38	pure
CY2013	us-gaap	Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance	0.37	pure
CY2011	us-gaap	Effective Income Tax Rate Continuing Operations EffectiveIncomeTaxRateContinuingOperations	-0.08	pure
CY2012	us-gaap	Effective Income Tax Rate Continuing Operations EffectiveIncomeTaxRateContinuingOperations	-0.06	pure
CY2013	us-gaap	Effective Income Tax Rate Continuing Operations EffectiveIncomeTaxRateContinuingOperations	-0.06	pure
CY2011	fold	Income Tax Expenses Benefit From Sale Of Net Operating Losses And Research And Development Credits IncomeTaxExpensesBenefitFromSaleOfNetOperatingLossesAndResearchAndDevelopmentCredits	3600000	USD
CY2013Q4	us-gaap	Secured Debt SecuredDebt	15299000	USD
CY2013Q4	us-gaap	Secured Debt Current SecuredDebtCurrent	299000	USD
CY2007	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	458000	USD
CY2012	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	1630000	USD
CY2012Q1	us-gaap	Net Income Loss NetIncomeLoss	-13137000	USD
CY2012Q2	us-gaap	Net Income Loss NetIncomeLoss	-9343000	USD
CY2012Q3	us-gaap	Net Income Loss NetIncomeLoss	-16290000	USD
CY2012Q4	us-gaap	Net Income Loss NetIncomeLoss	-10015000	USD
CY2013Q1	us-gaap	Net Income Loss NetIncomeLoss	-17458000	USD
CY2013Q2	us-gaap	Net Income Loss NetIncomeLoss	-15349000	USD
CY2013Q3	us-gaap	Net Income Loss NetIncomeLoss	-14589000	USD
CY2013Q4	us-gaap	Net Income Loss NetIncomeLoss	-12237000	USD
CY2012Q1	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.35
CY2012Q2	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.20
CY2012Q3	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.34
CY2012Q4	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.20
CY2013Q1	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.35
CY2013Q2	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.31
CY2013Q3	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.29
CY2013Q4	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-0.22
CY2008Q4	us-gaap	Stockholders Equity StockholdersEquity	71043000	USD
CY2009Q4	us-gaap	Stockholders Equity StockholdersEquity	71833000	USD
CY2010Q4	us-gaap	Stockholders Equity StockholdersEquity	64934000	USD
CY2011Q4	us-gaap	Stockholders Equity StockholdersEquity	29592000	USD
CY2006	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	158000	USD
CY2012	us-gaap	Stock Issued During Period Value Share Based Compensation StockIssuedDuringPeriodValueShareBasedCompensation	6191000	USD
CY2010	us-gaap	Stock Issued During Period Value Share Based Compensation StockIssuedDuringPeriodValueShareBasedCompensation	6186000	USD
CY2005	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	-7000	USD
	us-gaap	Net Income Loss NetIncomeLoss	-1775000	USD
CY2012	us-gaap	Stock Issued During Period Value New Issues StockIssuedDuringPeriodValueNewIssues	62055000	USD
CY2011	us-gaap	Stock Issued During Period Value Share Based Compensation StockIssuedDuringPeriodValueShareBasedCompensation	8678000	USD
CY2006	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	31000	USD
CY2003	us-gaap	Net Income Loss NetIncomeLoss	-6768000	USD
CY2005	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	24000	USD
CY2012Q4	us-gaap	Deferred Tax Assets Property Plant And Equipment DeferredTaxAssetsPropertyPlantAndEquipment	3176000	USD
CY2012Q4	us-gaap	Deferred Tax Assets Tax Credit Carryforwards Research DeferredTaxAssetsTaxCreditCarryforwardsResearch	9072000	USD
CY2012Q4	us-gaap	Deferred Tax Assets Operating Loss Carryforwards DeferredTaxAssetsOperatingLossCarryforwards	62060000	USD
CY2008	us-gaap	Stock Issued During Period Value Share Based Compensation StockIssuedDuringPeriodValueShareBasedCompensation	6446000	USD
CY2006	us-gaap	Stock Issued During Period Value Share Based Compensation StockIssuedDuringPeriodValueShareBasedCompensation	2816000	USD
CY2007	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	393000	USD
CY2004	us-gaap	Net Income Loss NetIncomeLoss	-8807000	USD
CY2010	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	9000	USD
CY2012	fold	Stock Issued During Period Value Warrants Exercised StockIssuedDuringPeriodValueWarrantsExercised	387000	USD
CY2007	us-gaap	Stock Issued During Period Value Share Based Compensation StockIssuedDuringPeriodValueShareBasedCompensation	3823000	USD
CY2012	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	10000	USD
CY2005	us-gaap	Net Income Loss NetIncomeLoss	-19972000	USD
CY2007Q4	us-gaap	Stockholders Equity StockholdersEquity	103297000	USD
CY2002Q4	us-gaap	Stockholders Equity StockholdersEquity	-1249000	USD
CY2003Q4	us-gaap	Stockholders Equity StockholdersEquity	-7709000	USD
CY2004Q4	us-gaap	Stockholders Equity StockholdersEquity	-16287000	USD
CY2005Q4	us-gaap	Stockholders Equity StockholdersEquity	-35829000	USD
CY2006Q4	us-gaap	Stockholders Equity StockholdersEquity	-77515000	USD
	us-gaap	Stock Issued During Period Value New Issues StockIssuedDuringPeriodValueNewIssues	84000	USD
CY2007	us-gaap	Stock Issued During Period Value New Issues StockIssuedDuringPeriodValueNewIssues	68145000	USD
CY2010	us-gaap	Stock Issued During Period Value New Issues StockIssuedDuringPeriodValueNewIssues	13830000	USD
	fold	Stock Issued For In Process Research And Development StockIssuedForInProcessResearchAndDevelopment	418000	USD
CY2007	us-gaap	Stock Issued During Period Value Conversion Of Convertible Securities StockIssuedDuringPeriodValueConversionOfConvertibleSecurities	148591000	USD
CY2012	fold	Stock Issued During Period Value Collaboration Agreement StockIssuedDuringPeriodValueCollaborationAgreement	18140000	USD
CY2010	fold	Stock Issued During Period Value Collaboration Agreement StockIssuedDuringPeriodValueCollaborationAgreement	28083000	USD
CY2011	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	360000	USD
CY2008	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	530000	USD
CY2009	us-gaap	Stock Issued During Period Value Stock Options Exercised StockIssuedDuringPeriodValueStockOptionsExercised	60000	USD
CY2005	fold	Stock Issued During Period Value Warrants Exercised StockIssuedDuringPeriodValueWarrantsExercised	75000	USD
	fold	Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Value Amortization AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRequisiteServicePeriodRecognitionValueAmortization	27000	USD
CY2003	fold	Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Value Amortization AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRequisiteServicePeriodRecognitionValueAmortization	70000	USD
CY2004	fold	Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Value Amortization AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRequisiteServicePeriodRecognitionValueAmortization	60000	USD
CY2005	fold	Adjustments To Additional Paid In Capital Share Based Compensation Requisite Service Period Recognition Value Amortization AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRequisiteServicePeriodRecognitionValueAmortization	365000	USD
CY2006	fold	Stock Issued During Period Value License Payment StockIssuedDuringPeriodValueLicensePayment	1220000	USD
CY2012Q4	fold	Deferred Tax Assets Non Cash Stock Issue Current DeferredTaxAssetsNonCashStockIssueCurrent	7100000	USD
CY2012	fold	Class Of Warrant Or Right Exercised ClassOfWarrantOrRightExercised	500000	shares
CY2012Q4	fold	Deferred Tax Assets Other Current DeferredTaxAssetsOtherCurrent	1257000	USD
CY2012Q4	us-gaap	Deferred Tax Assets Gross Current DeferredTaxAssetsGrossCurrent	8357000	USD
CY2012Q4	us-gaap	Deferred Tax Assets Deferred Income DeferredTaxAssetsDeferredIncome	12149000	USD
CY2012Q4	fold	Deferred Tax Assets Other Noncurrent DeferredTaxAssetsOtherNoncurrent	520000	USD
CY2012Q4	us-gaap	Deferred Tax Assets Gross DeferredTaxAssetsGross	95334000	USD
CY2012Q4	fold	Deferred Tax Assets Liabilities Gross DeferredTaxAssetsLiabilitiesGross	95334000	USD
CY2012Q4	us-gaap	Deferred Tax Assets Valuation Allowance DeferredTaxAssetsValuationAllowance	95334000	USD
CY2013Q4	fold	Deferred Tax Assets Non Cash Stock Issue Current DeferredTaxAssetsNonCashStockIssueCurrent	8172000	USD
CY2013Q4	fold	Deferred Tax Assets Other Current DeferredTaxAssetsOtherCurrent	1343000	USD
	us-gaap	Adjustments To Additional Paid In Capital Warrant Issued AdjustmentsToAdditionalPaidInCapitalWarrantIssued	8000	USD
CY2003	us-gaap	Adjustments To Additional Paid In Capital Warrant Issued AdjustmentsToAdditionalPaidInCapitalWarrantIssued	210000	USD
CY2003	us-gaap	Share Based Goods And Nonemployee Services Transaction Stockholders Equity ShareBasedGoodsAndNonemployeeServicesTransactionStockholdersEquity	4000	USD
CY2013Q4	us-gaap	Deferred Tax Assets Deferred Income DeferredTaxAssetsDeferredIncome	14649000	USD
CY2004	us-gaap	Share Based Goods And Nonemployee Services Transaction Stockholders Equity ShareBasedGoodsAndNonemployeeServicesTransactionStockholdersEquity	16000	USD
CY2005	us-gaap	Share Based Goods And Nonemployee Services Transaction Stockholders Equity ShareBasedGoodsAndNonemployeeServicesTransactionStockholdersEquity	112000	USD
CY2013	us-gaap	Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate	-0.34	pure
CY2011	us-gaap	Effective Income Tax Rate Reconciliation State And Local Income Taxes EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes	-0.13	pure
CY2012	us-gaap	Effective Income Tax Rate Reconciliation State And Local Income Taxes EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes	-0.03	pure
CY2013	us-gaap	Effective Income Tax Rate Reconciliation State And Local Income Taxes EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes	-0.05	pure
CY2013Q4	us-gaap	Deferred Tax Assets Gross Current DeferredTaxAssetsGrossCurrent	9515000	USD
CY2013Q4	us-gaap	Deferred Tax Assets Property Plant And Equipment DeferredTaxAssetsPropertyPlantAndEquipment	3068000	USD
CY2013Q4	fold	Deferred Tax Assets Other Noncurrent DeferredTaxAssetsOtherNoncurrent	682000	USD
CY2013Q4	us-gaap	Deferred Tax Assets Gross DeferredTaxAssetsGross	121578000	USD
CY2010Q1	us-gaap	Class Of Warrant Or Right Exercise Price Of Warrants Or Rights ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights	4.43
CY2011	us-gaap	Effective Income Tax Rate Reconciliation Nondeductible Expense EffectiveIncomeTaxRateReconciliationNondeductibleExpense	0.03	pure
CY2012	us-gaap	Effective Income Tax Rate Reconciliation Tax Credits Research EffectiveIncomeTaxRateReconciliationTaxCreditsResearch	0.08	pure
CY2013	us-gaap	Effective Income Tax Rate Reconciliation Tax Credits Research EffectiveIncomeTaxRateReconciliationTaxCreditsResearch	0.03	pure
CY2011	us-gaap	Effective Income Tax Rate Reconciliation Other Adjustments EffectiveIncomeTaxRateReconciliationOtherAdjustments	0.02	pure
CY2013Q4	fold	Deferred Tax Assets Liabilities Gross DeferredTaxAssetsLiabilitiesGross	112392000	USD
CY2013Q4	us-gaap	Deferred Tax Assets Valuation Allowance DeferredTaxAssetsValuationAllowance	121578000	USD
CY2012	us-gaap	Valuation Allowance Deferred Tax Asset Change In Amount ValuationAllowanceDeferredTaxAssetChangeInAmount	20100000	USD
CY2013	us-gaap	Valuation Allowance Deferred Tax Asset Change In Amount ValuationAllowanceDeferredTaxAssetChangeInAmount	26300000	USD
CY2013	fold	Operating Loss Carryforwards Limitations On Use Minimum Ownership Percentage Change Relating To Section382 OperatingLossCarryforwardsLimitationsOnUseMinimumOwnershipPercentageChangeRelatingToSection382	0.50	pure
CY2013	fold	Operating Loss Carryforwards Limitations On Use Minimum Percentage Ownership Change Period OperatingLossCarryforwardsLimitationsOnUseMinimumPercentageOwnershipChangePeriod	P3Y
CY2013	us-gaap	Effective Income Tax Rate Reconciliation Nondeductible Expense EffectiveIncomeTaxRateReconciliationNondeductibleExpense	-0.01	pure
CY2011	us-gaap	Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate	-0.34	pure
CY2012	us-gaap	Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate	-0.34	pure
CY2006	us-gaap	Share Based Goods And Nonemployee Services Transaction Stockholders Equity ShareBasedGoodsAndNonemployeeServicesTransactionStockholdersEquity	476000	USD
CY2007	us-gaap	Share Based Goods And Nonemployee Services Transaction Stockholders Equity ShareBasedGoodsAndNonemployeeServicesTransactionStockholdersEquity	162000	USD
CY2004	fold	Adjustments To Additional Paid In Capital Convertible Debt Interest Waiver AdjustmentsToAdditionalPaidInCapitalConvertibleDebtInterestWaiver	193000	USD
CY2009	us-gaap	Stock Issued During Period Value Share Based Compensation StockIssuedDuringPeriodValueShareBasedCompensation	7787000	USD
CY2013	us-gaap	Stock Issued During Period Value Share Based Compensation StockIssuedDuringPeriodValueShareBasedCompensation	6177000	USD
	us-gaap	Adjustments To Additional Paid In Capital Increase In Carrying Amount Of Redeemable Preferred Stock AdjustmentsToAdditionalPaidInCapitalIncreaseInCarryingAmountOfRedeemablePreferredStock	11000	USD
CY2003	us-gaap	Adjustments To Additional Paid In Capital Increase In Carrying Amount Of Redeemable Preferred Stock AdjustmentsToAdditionalPaidInCapitalIncreaseInCarryingAmountOfRedeemablePreferredStock	17000	USD
CY2004	us-gaap	Adjustments To Additional Paid In Capital Increase In Carrying Amount Of Redeemable Preferred Stock AdjustmentsToAdditionalPaidInCapitalIncreaseInCarryingAmountOfRedeemablePreferredStock	126000	USD
CY2005	us-gaap	Adjustments To Additional Paid In Capital Increase In Carrying Amount Of Redeemable Preferred Stock AdjustmentsToAdditionalPaidInCapitalIncreaseInCarryingAmountOfRedeemablePreferredStock	139000	USD
CY2006	us-gaap	Adjustments To Additional Paid In Capital Increase In Carrying Amount Of Redeemable Preferred Stock AdjustmentsToAdditionalPaidInCapitalIncreaseInCarryingAmountOfRedeemablePreferredStock	159000	USD
CY2006	fold	Adjustments To Additional Paid In Capital Reclassification On Conversion AdjustmentsToAdditionalPaidInCapitalReclassificationOnConversion	117000	USD
CY2006	fold	Adjustments To Additional Paid In Capital Convertible Debt With Conversion Feature Deemed Dividend AdjustmentsToAdditionalPaidInCapitalConvertibleDebtWithConversionFeatureDeemedDividend	19424000	USD
CY2007	fold	Adjustments To Additional Paid In Capital Warrants Charge AdjustmentsToAdditionalPaidInCapitalWarrantsCharge	758000	USD
CY2003	us-gaap	Adjustments To Additional Paid In Capital Convertible Debt With Conversion Feature AdjustmentsToAdditionalPaidInCapitalConvertibleDebtWithConversionFeature	41000	USD
CY2004	us-gaap	Adjustments To Additional Paid In Capital Convertible Debt With Conversion Feature AdjustmentsToAdditionalPaidInCapitalConvertibleDebtWithConversionFeature	95000	USD
CY2006	us-gaap	Adjustments To Additional Paid In Capital Convertible Debt With Conversion Feature AdjustmentsToAdditionalPaidInCapitalConvertibleDebtWithConversionFeature	19424000	USD
CY2010	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	-71000	USD
CY2011	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	32000	USD
CY2008	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	125000	USD
CY2009	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	-490000	USD
CY2007	us-gaap	Adjustments To Additional Paid In Capital Increase In Carrying Amount Of Redeemable Preferred Stock AdjustmentsToAdditionalPaidInCapitalIncreaseInCarryingAmountOfRedeemablePreferredStock	351000	USD
CY2008	us-gaap	Net Income Loss NetIncomeLoss	-39355000	USD
CY2006	us-gaap	Net Income Loss NetIncomeLoss	-46345000	USD
CY2007	us-gaap	Net Income Loss NetIncomeLoss	-41167000	USD
CY2009	us-gaap	Net Income Loss NetIncomeLoss	-6567000	USD
CY2013Q4	us-gaap	Goodwill Goodwill	11613000	USD
CY2010	us-gaap	Net Income Loss NetIncomeLoss	-54936000	USD
CY2011Q4	us-gaap	Common Stock Shares Outstanding CommonStockSharesOutstanding	34654206	shares
	us-gaap	Increase Decrease In Other Operating Assets IncreaseDecreaseInOtherOperatingAssets	466000	USD
	us-gaap	Increase Decrease In Accounts Payable And Accrued Liabilities IncreaseDecreaseInAccountsPayableAndAccruedLiabilities	6710000	USD
	us-gaap	Increase Decrease In Other Noncurrent Liabilities IncreaseDecreaseInOtherNoncurrentLiabilities	36677000	USD
CY2013Q4	us-gaap	Restructuring Charges RestructuringCharges	1900000	USD
CY2013	us-gaap	Restructuring Charges RestructuringCharges	1988000	USD
CY2013	us-gaap	Payments For Restructuring PaymentsForRestructuring	-88000	USD
CY2013Q4	us-gaap	Restructuring Reserve RestructuringReserve	1842000	USD
CY2013Q4	us-gaap	Capital Lease Obligations CapitalLeaseObligations	0	USD
CY2013Q4	us-gaap	Available For Sale Securities Current AvailableForSaleSecuritiesCurrent	38360000	USD
CY2013Q4	us-gaap	Receivables Net Current ReceivablesNetCurrent	759000	USD
CY2013Q4	us-gaap	Other Assets Current OtherAssetsCurrent	5519000	USD
CY2013Q4	us-gaap	Other Assets Noncurrent OtherAssetsNoncurrent	552000	USD
CY2013Q4	us-gaap	Deferred Credits And Other Liabilities Noncurrent DeferredCreditsAndOtherLiabilitiesNoncurrent	36677000	USD
CY2013Q4	us-gaap	Secured Long Term Debt SecuredLongTermDebt	14174000	USD
CY2013Q4	us-gaap	Common Stock Value CommonStockValue	679000	USD
CY2013Q4	us-gaap	Additional Paid In Capital Common Stock AdditionalPaidInCapitalCommonStock	423593000	USD
CY2013Q4	us-gaap	Accumulated Other Comprehensive Income Loss Net Of Tax AccumulatedOtherComprehensiveIncomeLossNetOfTax	1000	USD
CY2013	fold	Research Revenue ResearchRevenue	363000	USD
	fold	Research Revenue ResearchRevenue	57856000	USD
	fold	Collaboration Revenue CollaborationRevenue	64382000	USD
CY2013	us-gaap	Research And Development Expense Excluding Acquired In Process Cost ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost	41944000	USD
CY2013	us-gaap	General And Administrative Expense GeneralAndAdministrativeExpense	18893000	USD
	us-gaap	Research And Development Expense Excluding Acquired In Process Cost ResearchAndDevelopmentExpenseExcludingAcquiredInProcessCost	357837000	USD
	us-gaap	General And Administrative Expense GeneralAndAdministrativeExpense	151506000	USD
CY2013	us-gaap	Depreciation And Amortization DepreciationAndAmortization	1719000	USD
	us-gaap	Depreciation And Amortization DepreciationAndAmortization	13487000	USD
CY2013	us-gaap	Investment Income Interest InvestmentIncomeInterest	174000	USD
CY2013	us-gaap	Interest Expense InterestExpense	46000	USD
CY2013	us-gaap	Fair Value Adjustment Of Warrants FairValueAdjustmentOfWarrants	-908000	USD
	us-gaap	Investment Income Interest InvestmentIncomeInterest	14563000	USD
	us-gaap	Interest Expense InterestExpense	2468000	USD
	us-gaap	Fair Value Adjustment Of Warrants FairValueAdjustmentOfWarrants	-2461000	USD
	us-gaap	Other Nonoperating Income Expense OtherNonoperatingIncomeExpense	252000	USD
CY2013	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	-3512000	USD
	us-gaap	Income Tax Expense Benefit IncomeTaxExpenseBenefit	-12220000	USD
CY2013	us-gaap	Earnings Per Share Basic And Diluted EarningsPerShareBasicAndDiluted	-1.16
CY2013	us-gaap	Share Based Compensation ShareBasedCompensation	6177000	USD
CY2013Q4	us-gaap	Deferred Tax Assets Liabilities Net DeferredTaxAssetsLiabilitiesNet	-9186000	USD
	us-gaap	Share Based Compensation ShareBasedCompensation	48106000	USD
	us-gaap	Gain Loss On Sale Of Property Plant Equipment GainLossOnSaleOfPropertyPlantEquipment	-388000	USD
CY2013	us-gaap	Increase Decrease In Due From Related Parties Current IncreaseDecreaseInDueFromRelatedPartiesCurrent	-2466000	USD
CY2013	us-gaap	Increase Decrease In Prepaid Deferred Expense And Other Assets IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets	3249000	USD
CY2013	us-gaap	Increase Decrease In Accounts Payable And Accrued Liabilities IncreaseDecreaseInAccountsPayableAndAccruedLiabilities	-613000	USD
CY2013	us-gaap	Increase Decrease In Other Noncurrent Liabilities IncreaseDecreaseInOtherNoncurrentLiabilities	6259000	USD
	us-gaap	Increase Decrease In Due From Related Parties Current IncreaseDecreaseInDueFromRelatedPartiesCurrent	759000	USD
CY2013	us-gaap	Proceeds From Sale And Maturity Of Available For Sale Securities ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities	83337000	USD
CY2013	us-gaap	Payments To Acquire Available For Sale Securities PaymentsToAcquireAvailableForSaleSecurities	56559000	USD
CY2013	us-gaap	Payments To Acquire Property Plant And Equipment PaymentsToAcquirePropertyPlantAndEquipment	695000	USD
CY2013Q4	us-gaap	Goodwill Impaired Accumulated Impairment Loss GoodwillImpairedAccumulatedImpairmentLoss	0	USD
	us-gaap	Proceeds From Sale And Maturity Of Available For Sale Securities ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities	838779000	USD
	us-gaap	Payments To Acquire Available For Sale Securities PaymentsToAcquireAvailableForSaleSecurities	877254000	USD
	us-gaap	Payments To Acquire Property Plant And Equipment PaymentsToAcquirePropertyPlantAndEquipment	18908000	USD
CY2013	us-gaap	Proceeds From Issuance Of Common Stock ProceedsFromIssuanceOfCommonStock	15000000	USD
	us-gaap	Proceeds From Issuance Of Common Stock ProceedsFromIssuanceOfCommonStock	208441000	USD
	us-gaap	Repayments Of Long Term Capital Lease Obligations RepaymentsOfLongTermCapitalLeaseObligations	5587000	USD
CY2013	us-gaap	Repayments Of Secured Debt RepaymentsOfSecuredDebt	398000	USD
	us-gaap	Repayments Of Secured Debt RepaymentsOfSecuredDebt	4454000	USD
CY2013Q4	us-gaap	Business Combination Contingent Consideration Liability BusinessCombinationContingentConsiderationLiability	10600000	USD
	us-gaap	Payments Of Financing Costs PaymentsOfFinancingCosts	110000	USD
CY2013Q4	us-gaap	Intangible Assets Net Excluding Goodwill IntangibleAssetsNetExcludingGoodwill	23000000	USD
CY2013Q4	us-gaap	Deferred Tax Liabilities Gross Noncurrent DeferredTaxLiabilitiesGrossNoncurrent	9186000	USD
	us-gaap	Proceeds From Stock Options Exercised ProceedsFromStockOptionsExercised	3341000	USD
CY2013	us-gaap	Proceeds From Issuance Of Secured Debt ProceedsFromIssuanceOfSecuredDebt	14888000	USD
	us-gaap	Proceeds From Issuance Of Secured Debt ProceedsFromIssuanceOfSecuredDebt	19641000	USD
CY2013	us-gaap	Fair Value Measurement With Unobservable Inputs Reconciliation Recurring Basis Liability Period Increase Decrease FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPeriodIncreaseDecrease	10000000	USD
CY2013Q4	us-gaap	Other Liabilities Noncurrent OtherLiabilitiesNoncurrent	714000	USD
CY2012	us-gaap	Business Acquisitions Pro Forma Revenue BusinessAcquisitionsProFormaRevenue	18411000	USD
CY2012	us-gaap	Business Acquisitions Pro Forma Net Income Loss BusinessAcquisitionsProFormaNetIncomeLoss	-49807000	USD
CY2013Q4	us-gaap	Warrants And Rights Outstanding WarrantsAndRightsOutstanding	0	USD
CY2013Q4	us-gaap	Long Term Debt Maturities Repayments Of Principal In Next Twelve Months LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths	299000	USD
CY2013Q4	us-gaap	Long Term Debt Maturities Repayments Of Principal In Year Two LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo	4035000	USD
CY2013Q4	us-gaap	Long Term Debt Maturities Repayments Of Principal In Year Three LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree	5443000	USD
CY2013Q4	us-gaap	Long Term Debt Maturities Repayments Of Principal In Year Four LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour	5522000	USD
CY2011Q4	us-gaap	Accumulated Other Comprehensive Income Loss Net Of Tax AccumulatedOtherComprehensiveIncomeLossNetOfTax	4000	USD
	us-gaap	Proceeds From Issuance Of Warrants ProceedsFromIssuanceOfWarrants	1046000	USD
CY2013	us-gaap	Payments Of Financing Costs PaymentsOfFinancingCosts	110000	USD
CY2013	us-gaap	Business Acquisitions Pro Forma Revenue BusinessAcquisitionsProFormaRevenue	363000	USD
CY2013	us-gaap	Business Acquisitions Pro Forma Net Income Loss BusinessAcquisitionsProFormaNetIncomeLoss	-61804000	USD
CY2013	us-gaap	Stock Issued During Period Value Acquisitions StockIssuedDuringPeriodValueAcquisitions	15000000	USD
CY2013Q4	us-gaap	Stock Issued During Period Shares New Issues StockIssuedDuringPeriodSharesNewIssues	7500000	shares
CY2013Q4	us-gaap	Class Of Warrant Or Right Number Of Securities Called By Warrants Or Rights ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights	1600000	shares
CY2013	us-gaap	Goodwill Acquired During Period GoodwillAcquiredDuringPeriod	11613000	USD
CY2013	fold	Stock And Warrants Issued During Period Value New Issues StockAndWarrantsIssuedDuringPeriodValueNewIssues	15000000	USD
	us-gaap	Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax	1000	USD
	us-gaap	Other Comprehensive Income Loss Before Tax Portion Attributable To Parent OtherComprehensiveIncomeLossBeforeTaxPortionAttributableToParent	1000	USD
	us-gaap	Other Comprehensive Income Loss Net Of Tax Portion Attributable To Parent OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent	1000	USD
CY2013Q4	us-gaap	Proceeds From Issuance Of Private Placement ProceedsFromIssuanceOfPrivatePlacement	15000000	USD
CY2013	us-gaap	Indefinitelived Intangible Assets Acquired IndefinitelivedIntangibleAssetsAcquired	23000000	USD
CY2013	us-gaap	Impairment Of Intangible Assets Indefinitelived Excluding Goodwill ImpairmentOfIntangibleAssetsIndefinitelivedExcludingGoodwill	0	USD
CY2013Q4	us-gaap	Deferred Income Tax Liabilities DeferredIncomeTaxLiabilities	9186000	USD
CY2013	fold	Number Of Inputs Used To Determine Value Of Warrants NumberOfInputsUsedToDetermineValueOfWarrants	6	item
CY2013Q4	us-gaap	Debt Instrument Carrying Amount DebtInstrumentCarryingAmount	15000000	USD
CY2013Q4	us-gaap	Debt Instrument Unamortized Discount DebtInstrumentUnamortizedDiscount	826000	USD
CY2013Q4	us-gaap	Share Price SharePrice	2.12
CY2013	fold	Period Within Which Employee Termination Costs Will Be Paid PeriodWithinWhichEmployeeTerminationCostsWillBePaid	P1Y
CY2013	us-gaap	Adjustments To Additional Paid In Capital Tax Effect From Share Based Compensation AdjustmentsToAdditionalPaidInCapitalTaxEffectFromShareBasedCompensation	2000000	USD

Files In Submission

Name	View Source	Status
0001047469-14-001702-index-headers.html	Edgar Link	pending
0001047469-14-001702-index.html	Edgar Link	pending
0001047469-14-001702.txt	Edgar Link	pending
0001047469-14-001702-xbrl.zip	Edgar Link	pending
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a2218555zex-32_1.htm	Edgar Link	pending
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AMICUS THERAPEUTICS, INC. Stock $fold

2014 Q1 Form 10-K Financial Statement

#000104746914001702 Filed on March 03, 2014

Income Statement

Balance Sheet

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Facts In Submission

Files In Submission

$FOLD AMICUS THERAPEUTICS, INC. Stock $fold

2014 Q1 Form 10-K Financial Statement

#000104746914001702 Filed on March 03, 2014

Income Statement

Balance Sheet

Cashflow Statement

Facts In Submission

Files In Submission

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