$GYRE
GYRE THERAPEUTICS, INC.

2012 Form 10-K Financial Statement

#000119312513109464 Filed on March 15, 2013

View on sec.gov

Income Statement

Concept 2012 2011 Q4 2011 Q3
Revenue $57.86M $18.95M $18.96M
YoY Change -40.74% -19.38% -13.05%
Cost Of Revenue $0.00
YoY Change
Gross Profit $18.95M
YoY Change -19.36%
Gross Profit Margin 100.03%
Selling, General & Admin $13.19M $3.020M $2.840M
YoY Change 8.38% 27.97% 38.54%
% of Gross Profit 15.94%
Research & Development $49.09M $26.07M $25.44M
YoY Change -48.45% 15.92% 46.8%
% of Gross Profit 137.57%
Depreciation & Amortization $2.212M $600.0K $700.0K
YoY Change -10.81% 20.0% 16.67%
% of Gross Profit 3.17%
Operating Expenses $66.00M $29.09M $28.29M
YoY Change -38.54% 17.06% 45.98%
Operating Profit -$8.138M -$10.15M -$9.331M
YoY Change -16.49% 651.48% -485.58%
Interest Expense $86.00K $340.0K $280.0K
YoY Change -34.85% 6.25% -15.15%
% of Operating Profit
Other Income/Expense, Net $1.039M
YoY Change -14.56%
Pretax Income -$7.099M -$9.810M -$9.050M
YoY Change -16.77% 852.43% -430.29%
Income Tax -$101.0K $0.00 $0.00
% Of Pretax Income
Net Earnings -$6.998M -$9.805M -$9.054M
YoY Change -17.95% 353.94% -463.61%
Net Earnings / Revenue -12.09% -51.76% -47.77%
Basic Earnings Per Share -$0.21 -$0.29 -$0.27
Diluted Earnings Per Share -$0.21 -$0.29 -$0.27
COMMON SHARES
Basic Shares Outstanding 33.48M shares 33.38M shares 33.38M shares
Diluted Shares Outstanding 33.48M shares 33.38M shares 33.38M shares

Balance Sheet

Concept 2012 2011 Q4 2011 Q3
SHORT-TERM ASSETS
Cash & Short-Term Investments $125.0M $195.0M $213.5M
YoY Change -35.9% -8.88% -6.36%
Cash & Equivalents $78.20M $107.3M $130.5M
Short-Term Investments $46.70M $87.70M $82.90M
Other Short-Term Assets $1.400M $3.000M $2.700M
YoY Change -53.33% -6.25% -18.18%
Inventory
Prepaid Expenses $2.995M
Receivables $1.400M $200.0K $600.0K
Other Receivables $0.00 $0.00 $0.00
Total Short-Term Assets $127.7M $198.2M $216.8M
YoY Change -35.57% -9.12% -6.95%
LONG-TERM ASSETS
Property, Plant & Equipment $1.600M $5.035M $5.400M
YoY Change -68.0% -17.46% 8.0%
Goodwill
YoY Change
Intangibles
YoY Change
Long-Term Investments $60.00M $54.30M $57.40M
YoY Change 10.5% 41.04% 43.5%
Other Assets $100.0K $476.0K
YoY Change -80.0%
Total Long-Term Assets $61.90M $59.91M $62.90M
YoY Change 3.34% 34.02% 38.85%
TOTAL ASSETS
Total Short-Term Assets $127.7M $198.2M $216.8M
Total Long-Term Assets $61.90M $59.91M $62.90M
Total Assets $189.6M $258.1M $279.7M
YoY Change -26.54% -1.78% 0.5%
SHORT-TERM LIABILITIES
YoY Change
Accounts Payable $2.100M $3.489M $1.400M
YoY Change -40.0% -25.77% -77.78%
Accrued Expenses $6.100M $16.17M $16.10M
YoY Change -62.35% 53.97% 347.22%
Deferred Revenue
YoY Change
Short-Term Debt $0.00 $0.00 $0.00
YoY Change
Long-Term Debt Due $900.0K $1.241M $1.600M
YoY Change -25.0% -27.0% -5.88%
Total Short-Term Liabilities $11.30M $78.61M $93.60M
YoY Change -85.62% -20.35% -2.3%
LONG-TERM LIABILITIES
Long-Term Debt $1.100M $1.986M $2.200M
YoY Change -45.0% 52.77% 22.22%
Other Long-Term Liabilities $1.200M $3.200M $2.000M
YoY Change -62.5% -95.49% -97.79%
Total Long-Term Liabilities $2.300M $1.986M $4.200M
YoY Change -55.77% -97.25% -95.44%
TOTAL LIABILITIES
Total Short-Term Liabilities $11.30M $78.61M $93.60M
Total Long-Term Liabilities $2.300M $1.986M $4.200M
Total Liabilities $13.70M $83.84M $97.70M
YoY Change -83.65% -50.94% -48.0%
SHAREHOLDERS EQUITY
Retained Earnings -$226.9M
YoY Change
Common Stock $33.00K
YoY Change
Preferred Stock
YoY Change
Treasury Stock (at cost)
YoY Change
Treasury Stock Shares
Shareholders Equity $175.9M $174.3M $182.0M
YoY Change
Total Liabilities & Shareholders Equity $189.6M $258.1M $279.7M
YoY Change -26.54% -1.78% 0.5%

Cashflow Statement

Concept 2012 2011 Q4 2011 Q3
OPERATING ACTIVITIES
Net Income -$6.998M -$9.805M -$9.054M
YoY Change -17.95% 353.94% -463.61%
Depreciation, Depletion And Amortization $2.212M $600.0K $700.0K
YoY Change -10.81% 20.0% 16.67%
Cash From Operating Activities -$64.24M -$20.50M -$18.10M
YoY Change -23.27% 30.57% 6.47%
INVESTING ACTIVITIES
Capital Expenditures $333.0K -$200.0K -$200.0K
YoY Change -76.73% -87.5% 0.0%
Acquisitions
YoY Change
Other Investing Activities $40.20M -$1.900M -$18.80M
YoY Change -171.53% -58.7% -5.53%
Cash From Investing Activities $39.82M -$2.200M -$19.00M
YoY Change -169.06% -64.52% -5.47%
FINANCING ACTIVITIES
Cash Dividend Paid
YoY Change
Common Stock Issuance & Retirement, Net $614.0K
YoY Change -99.26%
Debt Paid & Issued, Net $1.240M
YoY Change -36.86%
Cash From Financing Activities -626.0K -600.0K -500.0K
YoY Change -100.76% -130.0% -141.67%
NET CHANGE
Cash From Operating Activities -64.24M -20.50M -18.10M
Cash From Investing Activities 39.82M -2.200M -19.00M
Cash From Financing Activities -626.0K -600.0K -500.0K
Net Change In Cash -25.04M -23.30M -37.60M
YoY Change -57.24% 17.09% 4.74%
FREE CASH FLOW
Cash From Operating Activities -$64.24M -$20.50M -$18.10M
Capital Expenditures $333.0K -$200.0K -$200.0K
Free Cash Flow -$64.57M -$20.30M -$17.90M
YoY Change -24.17% 43.97% 6.55%

Facts In Submission

Frame Concept Type Concept / XBRL Key Value Unit
CY2013Q1 dei Entity Common Stock Shares Outstanding
EntityCommonStockSharesOutstanding
33616675 shares
CY2009Q3 trgt Amount Received For Research And Development Process Recognized
AmountReceivedForResearchAndDevelopmentProcessRecognized
10000000
CY2011Q2 trgt Common Stock Initial Public Offering Shares Issued
CommonStockInitialPublicOfferingSharesIssued
3658537 shares
CY2011Q2 trgt Common Stock Issued Upon Full Exercise Of Underwriters Over Allotment Option
CommonStockIssuedUponFullExerciseOfUnderwritersOverAllotmentOption
548780 shares
CY2012Q2 dei Entity Public Float
EntityPublicFloat
123869997
CY2009Q4 us-gaap Stockholders Equity
StockholdersEquity
68991000
CY2009Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
1886000
CY2009Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
83909000
CY2010Q4 us-gaap Stockholders Equity
StockholdersEquity
91847000
CY2011Q4 us-gaap Availableforsale Securities Gross Unrealized Gain
AvailableforsaleSecuritiesGrossUnrealizedGain
183000
CY2011Q4 us-gaap Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
0.001
CY2011Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
258126000
CY2011Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
107283000
CY2011Q4 us-gaap Available For Sale Securities Gross Unrealized Losses1
AvailableForSaleSecuritiesGrossUnrealizedLosses1
147000
CY2010Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
1474000
CY2010Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
165854000
CY2011Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
17867000
CY2011Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
312000
CY2011Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
82356000
CY2011Q4 us-gaap Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
CY2011Q4 us-gaap Other Assets Noncurrent
OtherAssetsNoncurrent
476000
CY2011Q4 us-gaap Stockholders Equity
StockholdersEquity
174288000
CY2011Q4 us-gaap Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
132000
CY2011Q4 us-gaap Available For Sale Securities Amortized Cost
AvailableForSaleSecuritiesAmortizedCost
157951000
CY2011Q4 us-gaap Marketable Securities Noncurrent
MarketableSecuritiesNoncurrent
54266000
CY2011Q4 us-gaap Commitments And Contingencies
CommitmentsAndContingencies
CY2011Q4 us-gaap Deferred Compensation Arrangement With Individual Common Stock Reserved For Future Issuance
DeferredCompensationArrangementWithIndividualCommonStockReservedForFutureIssuance
3779866 shares
CY2011Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
130000
CY2011Q4 us-gaap Finite Lived Patents Gross
FiniteLivedPatentsGross
296000
CY2011Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
100000000 shares
CY2011Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
33383403 shares
CY2011Q4 us-gaap Marketable Securities Current
MarketableSecuritiesCurrent
87721000
CY2011Q4 us-gaap Liabilities
Liabilities
83838000
CY2011Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
3489000
CY2011Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
1474000
CY2011Q4 us-gaap Prepaid Expense Current
PrepaidExpenseCurrent
2995000
CY2011Q4 us-gaap Deferred Revenue Current
DeferredRevenueCurrent
57714000
CY2011Q4 us-gaap Deferred Tax Assets Other
DeferredTaxAssetsOther
48000
CY2011Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
13.28
CY2011Q4 us-gaap Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
5000000 shares
CY2011Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-226930000
CY2011Q4 us-gaap Assets
Assets
258126000
CY2011Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
14.51
CY2011Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
33383403 shares
CY2011Q4 us-gaap Accumulated Other Comprehensive Income Loss Net Of Tax
AccumulatedOtherComprehensiveIncomeLossNetOfTax
36000
CY2011Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
1376081 shares
CY2011Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
16167000
CY2011Q4 us-gaap Deferred Tax Liabilities Property Plant And Equipment
DeferredTaxLiabilitiesPropertyPlantAndEquipment
312000
CY2011Q4 us-gaap Liabilities Current
LiabilitiesCurrent
78611000
CY2011Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
3779866 shares
CY2011Q4 us-gaap Common Stock Value
CommonStockValue
33000
CY2011Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.001
CY2011Q4 us-gaap Deferred Revenue Noncurrent
DeferredRevenueNoncurrent
3241000
CY2011Q4 us-gaap Finite Lived Intangible Assets Accumulated Amortization
FiniteLivedIntangibleAssetsAccumulatedAmortization
164000
CY2011Q4 us-gaap Assets Current
AssetsCurrent
198217000
CY2011Q4 us-gaap Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
0 shares
CY2011Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
82668000
CY2011Q4 us-gaap Preferred Stock Shares Issued
PreferredStockSharesIssued
0 shares
CY2011Q4 us-gaap Preferred Stock Value
PreferredStockValue
CY2011Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
12832000
CY2011Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
5035000
CY2011Q4 us-gaap Long Term Debt Current
LongTermDebtCurrent
1241000
CY2011Q4 us-gaap Additional Paid In Capital
AdditionalPaidInCapital
401149000
CY2011Q4 us-gaap Long Term Debt Noncurrent
LongTermDebtNoncurrent
1986000
CY2011Q4 us-gaap Available For Sale Securities Fair Value Disclosure
AvailableForSaleSecuritiesFairValueDisclosure
157987000
CY2011Q4 trgt Deferred Tax Assets Intangible Assets
DeferredTaxAssetsIntangibleAssets
1968000
CY2011Q4 trgt Accrued Compensation Current
AccruedCompensationCurrent
1178000
CY2011Q4 trgt Deferred Tax Assets Research And Development
DeferredTaxAssetsResearchAndDevelopment
10049000
CY2011Q4 trgt Deferred Tax Assets Net Operating Loss Carry Forward
DeferredTaxAssetsNetOperatingLossCarryForward
45901000
CY2011Q4 trgt Unrecognized Tax Benefits Based On Tax Positions Related To Current And Prior Years Accrual Additional Interest
UnrecognizedTaxBenefitsBasedOnTaxPositionsRelatedToCurrentAndPriorYearsAccrualAdditionalInterest
CY2011Q4 trgt Deferred Tax Assets Share Based Compensation
DeferredTaxAssetsShareBasedCompensation
3509000
CY2011Q4 trgt Accrued Clinical And Preclinical Study Fees
AccruedClinicalAndPreclinicalStudyFees
14859000
CY2011Q4 trgt Receivables From Collaborations
ReceivablesFromCollaborations
218000
CY2011Q4 trgt Investment In Certificate Of Deposit Exceeded Under Federal Deposit Insurance Corporation Limit
InvestmentInCertificateOfDepositExceededUnderFederalDepositInsuranceCorporationLimit
102412000
CY2011Q4 trgt Deferred Tax Assets Collaboration Revenue
DeferredTaxAssetsCollaborationRevenue
21193000
CY2012Q4 us-gaap Operating Leases Future Minimum Payments Due Current
OperatingLeasesFutureMinimumPaymentsDueCurrent
556000
CY2012Q4 us-gaap Property Plant And Equipment Gross
PropertyPlantAndEquipmentGross
5508000
CY2012Q4 us-gaap Deferred Tax Assets Net
DeferredTaxAssetsNet
360000
CY2012Q4 us-gaap Deferred Tax Assets Valuation Allowance
DeferredTaxAssetsValuationAllowance
84101000
CY2012Q4 us-gaap Deferred Tax Assets Liabilities Net
DeferredTaxAssetsLiabilitiesNet
CY2012Q4 us-gaap Other Assets Noncurrent
OtherAssetsNoncurrent
116000
CY2012Q4 us-gaap Long Term Debt Maturities Repayments Of Principal In Year Three
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree
283000
CY2012Q4 us-gaap Long Term Debt Maturities Repayments Of Principal Remainder Of Fiscal Year
LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear
851000
CY2012Q4 us-gaap Stockholders Equity
StockholdersEquity
175915000
CY2012Q4 us-gaap Finite Lived Intangible Assets Net
FiniteLivedIntangibleAssetsNet
115000
CY2012Q4 us-gaap Operating Leases Future Minimum Payments Due In Four Years
OperatingLeasesFutureMinimumPaymentsDueInFourYears
CY2012Q4 us-gaap Available For Sale Securities Amortized Cost
AvailableForSaleSecuritiesAmortizedCost
106385000
CY2012Q4 us-gaap Marketable Securities Noncurrent
MarketableSecuritiesNoncurrent
59966000
CY2012Q4 us-gaap Commitments And Contingencies
CommitmentsAndContingencies
CY2012Q4 us-gaap Deferred Compensation Arrangement With Individual Common Stock Reserved For Future Issuance
DeferredCompensationArrangementWithIndividualCommonStockReservedForFutureIssuance
4369804 shares
CY2012Q4 us-gaap Other Accrued Liabilities Current
OtherAccruedLiabilitiesCurrent
56000
CY2012Q4 us-gaap Finite Lived Patents Gross
FiniteLivedPatentsGross
296000
CY2012Q4 us-gaap Common Stock Shares Authorized
CommonStockSharesAuthorized
100000000 shares
CY2012Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue
624538000
CY2012Q4 us-gaap Common Stock Shares Outstanding
CommonStockSharesOutstanding
33615081 shares
CY2012Q4 us-gaap Finite Lived Intangible Assets Accumulated Amortization
FiniteLivedIntangibleAssetsAccumulatedAmortization
181000
CY2012Q4 us-gaap Operating Leases Future Minimum Payments Due In Three Years
OperatingLeasesFutureMinimumPaymentsDueInThreeYears
327000
CY2012Q4 us-gaap Assets Current
AssetsCurrent
127743000
CY2012Q4 us-gaap Additional Paid In Capital
AdditionalPaidInCapital
409608000
CY2012Q4 us-gaap Long Term Debt Noncurrent
LongTermDebtNoncurrent
1136000
CY2012Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestOutstandingWeightedAverageExercisePrice
11.80
CY2012Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableNumber
2802294 shares
CY2012Q4 us-gaap Operating Leases Future Minimum Payments Due In Two Years
OperatingLeasesFutureMinimumPaymentsDueInTwoYears
507000
CY2012Q4 us-gaap Marketable Securities Current
MarketableSecuritiesCurrent
42721000
CY2012Q4 us-gaap Liabilities
Liabilities
13664000
CY2012Q4 us-gaap Accounts Payable Current
AccountsPayableCurrent
2056000
CY2012Q4 us-gaap Unrecognized Tax Benefits
UnrecognizedTaxBenefits
1474000
CY2012Q4 us-gaap Prepaid Expense Current
PrepaidExpenseCurrent
1402000
CY2012Q4 us-gaap Deferred Revenue Current
DeferredRevenueCurrent
2357000
CY2012Q4 us-gaap Deferred Tax Assets Other
DeferredTaxAssetsOther
94000
CY2012Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue
5.84
CY2012Q4 us-gaap Preferred Stock Shares Authorized
PreferredStockSharesAuthorized
5000000 shares
CY2012Q4 us-gaap Retained Earnings Accumulated Deficit
RetainedEarningsAccumulatedDeficit
-233928000
CY2012Q4 us-gaap Assets
Assets
189579000
CY2012Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Weighted Average Exercise Price
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice
10.84
CY2012Q4 us-gaap Availableforsale Securities Gross Unrealized Gain
AvailableforsaleSecuritiesGrossUnrealizedGain
317000
CY2012Q4 us-gaap Preferred Stock Par Or Stated Value Per Share
PreferredStockParOrStatedValuePerShare
0.001
CY2012Q4 us-gaap Liabilities And Stockholders Equity
LiabilitiesAndStockholdersEquity
189579000
CY2012Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Vested And Expected To Vest Exercisable Aggregate Intrinsic Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedAndExpectedToVestExercisableAggregateIntrinsicValue
608091000
CY2012Q4 us-gaap Long Term Debt
LongTermDebt
1987000
CY2012Q4 us-gaap Cash And Cash Equivalents At Carrying Value
CashAndCashEquivalentsAtCarryingValue
82240000
CY2012Q4 us-gaap Available For Sale Securities Gross Unrealized Losses1
AvailableForSaleSecuritiesGrossUnrealizedLosses1
15000
CY2012Q4 us-gaap Common Stock Shares Issued
CommonStockSharesIssued
33615081 shares
CY2012Q4 us-gaap Long Term Debt Maturities Repayments Of Principal In Year Two
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo
853000
CY2012Q4 us-gaap Accumulated Other Comprehensive Income Loss Net Of Tax
AccumulatedOtherComprehensiveIncomeLossNetOfTax
201000
CY2012Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Nonvested Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber
1567510 shares
CY2012Q4 us-gaap Accrued Liabilities Current
AccruedLiabilitiesCurrent
6085000
CY2012Q4 us-gaap Deferred Tax Liabilities Property Plant And Equipment
DeferredTaxLiabilitiesPropertyPlantAndEquipment
360000
CY2012Q4 us-gaap Liabilities Current
LiabilitiesCurrent
11349000
CY2012Q4 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Outstanding Number
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber
4369804 shares
CY2012Q4 us-gaap Common Stock Value
CommonStockValue
34000
CY2012Q4 us-gaap Common Stock Par Or Stated Value Per Share
CommonStockParOrStatedValuePerShare
0.001
CY2012Q4 us-gaap Long Term Debt Maturities Repayments Of Principal In Year Four
LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour
CY2012Q4 us-gaap Deferred Revenue Noncurrent
DeferredRevenueNoncurrent
1179000
CY2012Q4 us-gaap Preferred Stock Shares Outstanding
PreferredStockSharesOutstanding
0 shares
CY2012Q4 us-gaap Deferred Tax Assets Gross
DeferredTaxAssetsGross
84461000
CY2012Q4 us-gaap Preferred Stock Shares Issued
PreferredStockSharesIssued
0 shares
CY2012Q4 us-gaap Preferred Stock Value
PreferredStockValue
CY2012Q4 us-gaap Operating Leases Future Minimum Payments Due
OperatingLeasesFutureMinimumPaymentsDue
1390000
CY2012Q4 us-gaap Accumulated Depreciation Depletion And Amortization Property Plant And Equipment
AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
3869000
CY2012Q4 us-gaap Property Plant And Equipment Net
PropertyPlantAndEquipmentNet
1639000
CY2012Q4 us-gaap Long Term Debt Current
LongTermDebtCurrent
851000
CY2012Q4 us-gaap Available For Sale Securities Fair Value Disclosure
AvailableForSaleSecuritiesFairValueDisclosure
106687000
CY2012Q4 trgt Deferred Tax Assets Intangible Assets
DeferredTaxAssetsIntangibleAssets
1798000
CY2012Q4 trgt Accrued Compensation Current
AccruedCompensationCurrent
797000
CY2012Q4 trgt Operating Leases Future Minimum Payments Due In Five Years And Thereafter
OperatingLeasesFutureMinimumPaymentsDueInFiveYearsAndThereafter
CY2012Q4 trgt Deferred Tax Assets Research And Development
DeferredTaxAssetsResearchAndDevelopment
10033000
CY2012Q4 trgt Deferred Tax Assets Net Operating Loss Carry Forward
DeferredTaxAssetsNetOperatingLossCarryForward
65935000
CY2012Q4 trgt Number Of Stock Incentive Plans
NumberOfStockIncentivePlans
2 EquityPlan
CY2012Q4 trgt Unrecognized Tax Benefits Based On Tax Positions Related To Current And Prior Years Accrual Additional Interest
UnrecognizedTaxBenefitsBasedOnTaxPositionsRelatedToCurrentAndPriorYearsAccrualAdditionalInterest
CY2012Q4 trgt Deferred Tax Assets Share Based Compensation
DeferredTaxAssetsShareBasedCompensation
5260000
CY2012Q4 trgt Accrued Clinical And Preclinical Study Fees
AccruedClinicalAndPreclinicalStudyFees
5232000
CY2012Q4 trgt Receivables From Collaborations
ReceivablesFromCollaborations
1380000
CY2012Q4 trgt Unrealized Loss Position Period
UnrealizedLossPositionPeriod
Less than 12 months
CY2012Q4 trgt Book Value Of Property Plant And Equipment Sold
BookValueOfPropertyPlantAndEquipmentSold
1534000
CY2012Q4 trgt Investment In Certificate Of Deposit Exceeded Under Federal Deposit Insurance Corporation Limit
InvestmentInCertificateOfDepositExceededUnderFederalDepositInsuranceCorporationLimit
87081000
CY2012Q4 trgt Deferred Tax Assets Collaboration Revenue
DeferredTaxAssetsCollaborationRevenue
1341000
CY2012Q2 us-gaap Restructuring And Related Cost Number Of Positions Eliminated
RestructuringAndRelatedCostNumberOfPositionsEliminated
65 Person
CY2012Q2 us-gaap Restructuring And Related Cost Number Of Positions Eliminated Period Percent
RestructuringAndRelatedCostNumberOfPositionsEliminatedPeriodPercent
0.46 pure
CY2012Q2 us-gaap Severance Costs
SeveranceCosts
2312000
CY2012Q4 us-gaap Restructuring And Related Cost Number Of Positions Eliminated
RestructuringAndRelatedCostNumberOfPositionsEliminated
27 Person
CY2012Q4 us-gaap Restructuring And Related Cost Number Of Positions Eliminated Period Percent
RestructuringAndRelatedCostNumberOfPositionsEliminatedPeriodPercent
0.38 pure
CY2012Q4 us-gaap Severance Costs
SeveranceCosts
1406000
CY2008Q1 us-gaap Repayments Of Other Debt
RepaymentsOfOtherDebt
1679000
CY2012Q4 trgt Sublease Agreement Base Monthly Rent
SubleaseAgreementBaseMonthlyRent
22000
CY2012Q4 trgt Agreement Entry Date
AgreementEntryDate
2013-01-01
CY2012Q4 trgt Agreement Expiration Date
AgreementExpirationDate
2015-12-30
CY2012Q4 trgt Subleased Agreement Area
SubleasedAgreementArea
18282 sqft
CY2012Q4 trgt Annual Percentage Increases In Monthly Rental Payment
AnnualPercentageIncreasesInMonthlyRentalPayment
0.03 pure
CY2010 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
0.029 pure
CY2010 us-gaap Payments To Acquire Investments
PaymentsToAcquireInvestments
144012000
CY2010 us-gaap Operating Income Loss
OperatingIncomeLoss
13115000
CY2010 us-gaap Revenue From Grants
RevenueFromGrants
2333000
CY2010 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
3292000
CY2010 us-gaap Repayments Of Long Term Debt
RepaymentsOfLongTermDebt
1577000
CY2010 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense
EffectiveIncomeTaxRateReconciliationNondeductibleExpense
0.24 pure
CY2010 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
4937000
CY2010 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
11124000
CY2010 us-gaap Current Income Tax Expense Benefit
CurrentIncomeTaxExpenseBenefit
3526000
CY2010 us-gaap Adjustments To Additional Paid In Capital Tax Effect From Share Based Compensation
AdjustmentsToAdditionalPaidInCapitalTaxEffectFromShareBasedCompensation
3503000
CY2010 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
pure
CY2010 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
1997000
CY2010 us-gaap Share Based Compensation
ShareBasedCompensation
4937000
CY2010 us-gaap Effective Income Tax Rate Reconciliation Other Adjustments
EffectiveIncomeTaxRateReconciliationOtherAdjustments
-0.03 pure
CY2010 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
0.36
CY2010 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
0.01 pure
CY2010 us-gaap Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
-3802000
CY2010 us-gaap Proceeds From Sale Of Property Plant And Equipment
ProceedsFromSaleOfPropertyPlantAndEquipment
43000
CY2010 us-gaap Deferred Federal Income Tax Expense Benefit
DeferredFederalIncomeTaxExpenseBenefit
1519000
CY2010 us-gaap Unrecognized Tax Benefits Decreases Resulting From Prior Period Tax Positions
UnrecognizedTaxBenefitsDecreasesResultingFromPriorPeriodTaxPositions
412000
CY2010 us-gaap Defined Contribution Plan Maximum Annual Contribution Per Employee Percent
DefinedContributionPlanMaximumAnnualContributionPerEmployeePercent
0.04 pure
CY2010 us-gaap Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
-0.12 pure
CY2010 us-gaap Current Federal Tax Expense Benefit
CurrentFederalTaxExpenseBenefit
3086000
CY2010 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
P6Y3M7D
CY2010 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
138298000
CY2010 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
-62799000
CY2010 us-gaap Investment Income Interest
InvestmentIncomeInterest
1463000
CY2010 us-gaap Deferred State And Local Income Tax Expense Benefit
DeferredStateAndLocalIncomeTaxExpenseBenefit
-1321000
CY2010 us-gaap Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
11973000
CY2010 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.03 pure
CY2010 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
3311000
CY2010 us-gaap Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
81945000
CY2010 us-gaap Recognition Of Deferred Revenue
RecognitionOfDeferredRevenue
83767000
CY2010 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
8052000
CY2010 us-gaap Proceeds From Issuance Of Long Term Debt
ProceedsFromIssuanceOfLongTermDebt
1228000
CY2010 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
30150324 shares
CY2010 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
3292000
CY2010 us-gaap Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments
IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
14425000
CY2010 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
0.38
CY2010 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
64546000
CY2010 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
6446000
CY2010 us-gaap Defined Benefit Plan Contributions By Employer
DefinedBenefitPlanContributionsByEmployer
487000
CY2010 us-gaap Operating Expenses
OperatingExpenses
72598000
CY2010 us-gaap Excess Tax Benefit From Share Based Compensation Operating Activities
ExcessTaxBenefitFromShareBasedCompensationOperatingActivities
3503000
CY2010 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
0.75 pure
CY2010 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
28543408 shares
CY2010 us-gaap Current State And Local Tax Expense Benefit
CurrentStateAndLocalTaxExpenseBenefit
440000
CY2010 us-gaap Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
2003000
CY2010 us-gaap Weighted Average Number Diluted Shares Outstanding Adjustment
WeightedAverageNumberDilutedSharesOutstandingAdjustment
1606916 shares
CY2010 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.35 pure
CY2010 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
-198000
CY2010 us-gaap Revenues
Revenues
85713000
CY2010 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
-0.01 pure
CY2010 us-gaap Payments For Proceeds From Investments
PaymentsForProceedsFromInvestments
-84481000
CY2010 us-gaap Depreciation
Depreciation
1979000
CY2010 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
0.04 pure
CY2010 us-gaap Interest Paid
InterestPaid
156000
CY2010 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
850683 shares
CY2010 us-gaap Net Income Loss
NetIncomeLoss
10899000
CY2010 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
1310000
CY2010 us-gaap Excess Tax Benefit From Share Based Compensation Financing Activities
ExcessTaxBenefitFromShareBasedCompensationFinancingActivities
3503000
CY2010 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
3526000
CY2010 us-gaap Investment Income Amortization Of Premium
InvestmentIncomeAmortizationOfPremium
416000
CY2010 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
225000
CY2010 us-gaap License And Services Revenue
LicenseAndServicesRevenue
83380000
CY2010 us-gaap Interest Expense
InterestExpense
153000
CY2010 us-gaap Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax
225000
CY2010 trgt Increase Decrease In Other Assets
IncreaseDecreaseInOtherAssets
1815000
CY2010 trgt Stock Option Exercise And Related Tax Benefits
StockOptionExerciseAndRelatedTaxBenefits
3503000
CY2010 trgt Increase Decrease In Receivables From Collaborations
IncreaseDecreaseInReceivablesFromCollaborations
-200963000
CY2010 trgt Deferred Tax Assets Valuation Allowances
DeferredTaxAssetsValuationAllowances
-198000
CY2010 trgt Effective Income Tax Rate Reconciliation Revaluation Of Unrecognized Tax Benefits Reserve Requirements
EffectiveIncomeTaxRateReconciliationRevaluationOfUnrecognizedTaxBenefitsReserveRequirements
-0.03 pure
CY2010 trgt Collaboration Revenue As Percentage Of Net Operating Revenue
CollaborationRevenueAsPercentageOfNetOperatingRevenue
0.97 pure
CY2011 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
0.025 pure
CY2011 us-gaap Payments To Acquire Investments
PaymentsToAcquireInvestments
156253000
CY2011 us-gaap Operating Income Loss
OperatingIncomeLoss
-9745000
CY2011 us-gaap Revenue From Grants
RevenueFromGrants
658000
CY2011 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
82646000
CY2011 us-gaap Repayments Of Long Term Debt
RepaymentsOfLongTermDebt
1964000
CY2011 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
8513000
CY2011 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-8718000
CY2011 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
pure
CY2011 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
2480000
CY2011 us-gaap Share Based Compensation
ShareBasedCompensation
8513000
CY2011 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.27
CY2011 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
0.41 pure
CY2011 us-gaap Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
4419000
CY2011 us-gaap Proceeds From Sale Of Property Plant And Equipment
ProceedsFromSaleOfPropertyPlantAndEquipment
5000
CY2011 us-gaap Deferred Federal Income Tax Expense Benefit
DeferredFederalIncomeTaxExpenseBenefit
-6147000
CY2011 us-gaap Defined Contribution Plan Maximum Annual Contribution Per Employee Percent
DefinedContributionPlanMaximumAnnualContributionPerEmployeePercent
0.04 pure
CY2011 us-gaap Effective Income Tax Rate Reconciliation Tax Credits Research
EffectiveIncomeTaxRateReconciliationTaxCreditsResearch
0.19 pure
CY2011 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
P6Y
CY2011 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-83718000
CY2011 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
-57667000
CY2011 us-gaap Investment Income Interest
InvestmentIncomeInterest
1348000
CY2011 us-gaap Deferred State And Local Income Tax Expense Benefit
DeferredStateAndLocalIncomeTaxExpenseBenefit
-1095000
CY2011 us-gaap Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
5750000
CY2011 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.03 pure
CY2011 us-gaap Interest Expense
InterestExpense
132000
CY2011 us-gaap Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax
-189000
CY2011 trgt Increase Decrease In Other Assets
IncreaseDecreaseInOtherAssets
443000
CY2011 trgt Net Proceeds From Issuance Of Common Shares In Public Offering
NetProceedsFromIssuanceOfCommonSharesInPublicOffering
80840000
CY2011 us-gaap Stock Issued During Period Value New Issues
StockIssuedDuringPeriodValueNewIssues
80844000
CY2011 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
1431000
CY2011 us-gaap Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
-58571000
CY2011 us-gaap Recognition Of Deferred Revenue
RecognitionOfDeferredRevenue
97439000
CY2011 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
12167000
CY2011 us-gaap Proceeds From Issuance Of Long Term Debt
ProceedsFromIssuanceOfLongTermDebt
2132000
CY2011 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
31637283 shares
CY2011 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
1802000
CY2011 us-gaap Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments
IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
-8529000
CY2011 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.27
CY2011 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
95215000
CY2011 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
82814000
CY2011 us-gaap Defined Benefit Plan Contributions By Employer
DefinedBenefitPlanContributionsByEmployer
535000
CY2011 us-gaap Operating Expenses
OperatingExpenses
107382000
CY2011 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
0.67 pure
CY2011 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
31637283 shares
CY2011 us-gaap Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
2575000
CY2011 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.35 pure
CY2011 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
7242000
CY2011 us-gaap Revenues
Revenues
97637000
CY2011 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
-0.85 pure
CY2011 us-gaap Payments For Proceeds From Investments
PaymentsForProceedsFromInvestments
-100012000
CY2011 us-gaap Depreciation
Depreciation
2463000
CY2011 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
-0.13 pure
CY2011 us-gaap Interest Paid
InterestPaid
134000
CY2011 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
3597530 shares
CY2011 us-gaap Net Income Loss
NetIncomeLoss
-8529000
CY2011 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
1216000
CY2011 us-gaap Investment Income Amortization Of Premium
InvestmentIncomeAmortizationOfPremium
911000
CY2011 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
-189000
CY2011 us-gaap License And Services Revenue
LicenseAndServicesRevenue
96979000
CY2011 trgt Increase Decrease In Receivables From Collaborations
IncreaseDecreaseInReceivablesFromCollaborations
-620000
CY2011 trgt Deferred Tax Assets Valuation Allowances
DeferredTaxAssetsValuationAllowances
7242000
CY2011 trgt Collaboration Revenue As Percentage Of Net Operating Revenue
CollaborationRevenueAsPercentageOfNetOperatingRevenue
0.99 pure
CY2012 dei Trading Symbol
TradingSymbol
TRGT
CY2012 dei Entity Registrant Name
EntityRegistrantName
TARGACEPT INC
CY2012 dei Entity Current Reporting Status
EntityCurrentReportingStatus
Yes
CY2012 dei Amendment Flag
AmendmentFlag
false
CY2012 dei Entity Filer Category
EntityFilerCategory
Accelerated Filer
CY2012 dei Document Fiscal Period Focus
DocumentFiscalPeriodFocus
FY
CY2012 dei Entity Voluntary Filers
EntityVoluntaryFilers
No
CY2012 dei Document Fiscal Year Focus
DocumentFiscalYearFocus
2012
CY2012 dei Document Type
DocumentType
10-K
CY2012 dei Document Period End Date
DocumentPeriodEndDate
2012-12-31
CY2012 dei Entity Incorporation Date Of Incorporation
EntityIncorporationDateOfIncorporation
1997-03-07
CY2012 dei Entity Central Index Key
EntityCentralIndexKey
0001124105
CY2012 dei Entity Well Known Seasoned Issuer
EntityWellKnownSeasonedIssuer
No
CY2012 dei Current Fiscal Year End Date
CurrentFiscalYearEndDate
--12-31
CY2012 invest Investment Maturity Date Range Start1
InvestmentMaturityDateRangeStart1
2013-01-10
CY2012 invest Investment Maturity Date Range End1
InvestmentMaturityDateRangeEnd1
2015-12-07
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Risk Free Interest Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate
0.010 pure
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross
1713835 shares
CY2012 us-gaap Payments To Acquire Investments
PaymentsToAcquireInvestments
120972000
CY2012 us-gaap Operating Income Loss
OperatingIncomeLoss
-8138000
CY2012 us-gaap Revenue From Grants
RevenueFromGrants
440000
CY2012 us-gaap Proceeds From Issuance Of Common Stock
ProceedsFromIssuanceOfCommonStock
614000
CY2012 us-gaap Other Comprehensive Income Loss Tax
OtherComprehensiveIncomeLossTax
101000
CY2012 us-gaap Repayments Of Long Term Debt
RepaymentsOfLongTermDebt
1240000
CY2012 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense
EffectiveIncomeTaxRateReconciliationNondeductibleExpense
0.01 pure
CY2012 us-gaap Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value
AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue
7846000
CY2012 us-gaap Comprehensive Income Net Of Tax
ComprehensiveIncomeNetOfTax
-6833000
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod
1713835 shares
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Dividend Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate
pure
CY2012 us-gaap Depreciation Depletion And Amortization
DepreciationDepletionAndAmortization
2212000
CY2012 us-gaap Share Based Compensation
ShareBasedCompensation
7846000
CY2012 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Grants In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice
4.54
CY2012 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.21
CY2012 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Other
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseOther
0.04 pure
CY2012 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Forfeitures In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice
16.38
CY2012 us-gaap Increase Decrease In Accounts Payable And Accrued Liabilities
IncreaseDecreaseInAccountsPayableAndAccruedLiabilities
-11515000
CY2012 us-gaap Proceeds From Sale Of Property Plant And Equipment
ProceedsFromSaleOfPropertyPlantAndEquipment
1589000
CY2012 us-gaap Deferred Federal Income Tax Expense Benefit
DeferredFederalIncomeTaxExpenseBenefit
-1128000
CY2012 us-gaap Stock Issued During Period Shares Stock Options Exercised
StockIssuedDuringPeriodSharesStockOptionsExercised
231678 shares
CY2012 us-gaap Defined Contribution Plan Maximum Annual Contribution Per Employee Percent
DefinedContributionPlanMaximumAnnualContributionPerEmployeePercent
0.04 pure
CY2012 us-gaap Concentration Risk Credit Risk
ConcentrationRiskCreditRisk
<div> <p style="MARGIN-TOP: 18px; MARGIN-BOTTOM: 0px"><font style="FONT-FAMILY: Times New Roman" size="2"><i>Credit Risk</i></font></p> <p style="MARGIN-TOP: 6px; TEXT-INDENT: 4%; MARGIN-BOTTOM: 0px"> <font style="FONT-FAMILY: Times New Roman" size="2">Financial instruments that potentially subject the Company to credit risk consist principally of cash, investments in marketable securities and receivables from collaborations. The Company has established guidelines for investment of its cash that are designed to emphasize safety, liquidity and preservation of capital. The Company places its cash and cash equivalents with prominent financial institutions. At December&#xA0;31, 2012 and 2011, the Company had deposits in excess of federally insured limits of $87,081,000 and $102,412,000, respectively.</font></p> </div>
CY2012 us-gaap Cash And Cash Equivalents Period Increase Decrease
CashAndCashEquivalentsPeriodIncreaseDecrease
-25043000
CY2012 us-gaap Recognition Of Deferred Revenue
RecognitionOfDeferredRevenue
57860000
CY2012 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Fair Value Assumptions Expected Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1
P6Y1M28D
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue
8.80
CY2011Q1 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
0.41
CY2012 us-gaap General And Administrative Expense
GeneralAndAdministrativeExpense
13193000
CY2011Q1 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
30399750 shares
CY2011Q1 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
0.43
CY2011Q1 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
28996060 shares
CY2012 us-gaap Net Cash Provided By Used In Operating Activities
NetCashProvidedByUsedInOperatingActivities
-64239000
CY2012 us-gaap Net Cash Provided By Used In Investing Activities
NetCashProvidedByUsedInInvestingActivities
39822000
CY2012 us-gaap Investment Income Interest
InvestmentIncomeInterest
1070000
CY2012 us-gaap Deferred State And Local Income Tax Expense Benefit
DeferredStateAndLocalIncomeTaxExpenseBenefit
-718000
CY2012 us-gaap Increase Decrease In Deferred Revenue
IncreaseDecreaseInDeferredRevenue
440000
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Vested In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod
891443 shares
CY2012 us-gaap Share Based Compensation Arrangements By Share Based Payment Award Options Exercises In Period Weighted Average Exercise Price
ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExercisesInPeriodWeightedAverageExercisePrice
2.65
CY2012 us-gaap Effective Income Tax Rate Reconciliation State And Local Income Taxes
EffectiveIncomeTaxRateReconciliationStateAndLocalIncomeTaxes
0.02 pure
CY2012 us-gaap Payments To Acquire Property Plant And Equipment
PaymentsToAcquirePropertyPlantAndEquipment
333000
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeitures Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue
10.15
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Grants In Period Weighted Average Grant Date Fair Value
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue
2.98
CY2012 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
33476316 shares
CY2012 us-gaap Stock Issued During Period Value Stock Options Exercised
StockIssuedDuringPeriodValueStockOptionsExercised
614000
CY2012 us-gaap Income Loss From Continuing Operations Before Income Taxes Minority Interest And Income Loss From Equity Method Investments
IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments
-7099000
CY2012 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.21
CY2012 us-gaap Research And Development Expense
ResearchAndDevelopmentExpense
49087000
CY2012 us-gaap Net Cash Provided By Used In Financing Activities
NetCashProvidedByUsedInFinancingActivities
-626000
CY2012 us-gaap Defined Benefit Plan Contributions By Employer
DefinedBenefitPlanContributionsByEmployer
454000
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Options Forfeitures In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod
892219 shares
CY2012 us-gaap Other Comprehensive Income Loss Reclassification Adjustment For Sale Of Securities Included In Net Income Before Tax
OtherComprehensiveIncomeLossReclassificationAdjustmentForSaleOfSecuritiesIncludedInNetIncomeBeforeTax
-78000
CY2012 us-gaap Operating Expenses
OperatingExpenses
65998000
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Fair Value Assumptions Expected Volatility Rate
ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate
0.69 pure
CY2012 trgt Increase Decrease In Other Assets
IncreaseDecreaseInOtherAssets
-2017000
CY2012 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
33476316 shares
CY2012 us-gaap Operating Leases Rent Expense Net
OperatingLeasesRentExpenseNet
2819000
CY2012 us-gaap Effective Income Tax Rate Reconciliation At Federal Statutory Income Tax Rate
EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate
0.35 pure
CY2012 us-gaap Valuation Allowance Deferred Tax Asset Change In Amount
ValuationAllowanceDeferredTaxAssetChangeInAmount
1745000
CY2012 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Vested And Expected To Vest Exercisable Weighted Average Remaining Contractual Term1
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedAndExpectedToVestExercisableWeightedAverageRemainingContractualTerm1
P4Y8M12D
CY2012 us-gaap Sharebased Compensation Arrangement By Sharebased Payment Award Options Outstanding Weighted Average Remaining Contractual Term2
SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2
P6Y3M18D
CY2012 us-gaap Revenues
Revenues
57860000
CY2012 us-gaap Effective Income Tax Rate Reconciliation Change In Deferred Tax Assets Valuation Allowance
EffectiveIncomeTaxRateReconciliationChangeInDeferredTaxAssetsValuationAllowance
-0.25 pure
CY2012 us-gaap Payments For Proceeds From Investments
PaymentsForProceedsFromInvestments
-159538000
CY2012 us-gaap Depreciation
Depreciation
2195000
CY2012 us-gaap Effective Income Tax Rate Reconciliation Nondeductible Expense Share Based Compensation Cost
EffectiveIncomeTaxRateReconciliationNondeductibleExpenseShareBasedCompensationCost
-0.15 pure
CY2012 us-gaap Gain Loss On Sale Of Property Plant Equipment
GainLossOnSaleOfPropertyPlantEquipment
55000
CY2012 us-gaap Interest Paid
InterestPaid
91000
CY2012 us-gaap Deferred Income Tax Expense Benefit
DeferredIncomeTaxExpenseBenefit
-101000
CY2012 us-gaap Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount
AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount
4250964 shares
CY2012 us-gaap Other Comprehensive Income Loss Available For Sale Securities Adjustment Before Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentBeforeTax
344000
CY2012 us-gaap Net Income Loss
NetIncomeLoss
-6998000
CY2012 us-gaap Nonoperating Income Expense
NonoperatingIncomeExpense
1039000
CY2012 us-gaap Income Tax Expense Benefit
IncomeTaxExpenseBenefit
-101000
CY2012 us-gaap Investment Income Amortization Of Premium
InvestmentIncomeAmortizationOfPremium
937000
CY2012 us-gaap Other Comprehensive Income Unrealized Holding Gain Loss On Securities Arising During Period Net Of Tax
OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax
165000
CY2012 us-gaap License And Services Revenue
LicenseAndServicesRevenue
57420000
CY2012 us-gaap Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Forfeited In Period
ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod
630963 shares
CY2012 us-gaap Interest Expense
InterestExpense
86000
CY2012 us-gaap Other Comprehensive Income Loss Available For Sale Securities Adjustment Net Of Tax
OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax
165000
CY2012 trgt Future Amortization Expense Under In Process Research And Development
FutureAmortizationExpenseUnderInProcessResearchAndDevelopment
17000
CY2012 trgt Net Gain On Asset Sales
NetGainOnAssetSales
55000
CY2012 trgt Number Of Years Amortized
NumberOfYearsAmortized
17 Y
CY2012 trgt Expenses Related To Reduction In Workforce
ExpensesRelatedToReductionInWorkforce
3718000
CY2012 trgt Other Comprehensive Income Deferred Income Tax Expense Benefit
OtherComprehensiveIncomeDeferredIncomeTaxExpenseBenefit
-101000
CY2012 trgt Stock Option Exercise And Related Tax Benefits
StockOptionExerciseAndRelatedTaxBenefits
7540000
CY2012 trgt Increase Decrease In Receivables From Collaborations
IncreaseDecreaseInReceivablesFromCollaborations
1162000
CY2012 trgt Deferred Tax Assets Valuation Allowances
DeferredTaxAssetsValuationAllowances
1745000
CY2012 trgt Collaboration Revenue As Percentage Of Net Operating Revenue
CollaborationRevenueAsPercentageOfNetOperatingRevenue
0.99 pure
CY2012 trgt Weighted Average Maturity Date
WeightedAverageMaturityDate
2014-04-23
CY2011Q1 us-gaap Operating Income Loss
OperatingIncomeLoss
12302000
CY2011Q1 us-gaap Revenues
Revenues
38994000
CY2011Q1 us-gaap Net Income Loss
NetIncomeLoss
12587000
CY2011Q2 us-gaap Operating Income Loss
OperatingIncomeLoss
-2571000
CY2011Q2 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.07
CY2011Q2 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
30725227 shares
CY2011Q2 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.07
CY2011Q2 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
30725227 shares
CY2011Q2 us-gaap Revenues
Revenues
20743000
CY2011Q2 us-gaap Net Income Loss
NetIncomeLoss
-2257000
CY2012Q1 us-gaap Operating Income Loss
OperatingIncomeLoss
1986000
CY2012Q1 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
0.07
CY2012Q1 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
33822010 shares
CY2012Q1 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
0.07
CY2012Q1 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
33390286 shares
CY2012Q1 us-gaap Revenues
Revenues
22857000
CY2012Q1 us-gaap Net Income Loss
NetIncomeLoss
2259000
CY2012Q2 us-gaap Operating Income Loss
OperatingIncomeLoss
14234000
CY2012Q2 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
0.43
CY2012Q2 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
33638629 shares
CY2012Q2 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
0.43
CY2012Q2 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
33409341 shares
CY2012Q2 us-gaap Revenues
Revenues
33645000
CY2012Q2 us-gaap Net Income Loss
NetIncomeLoss
14492000
CY2011Q3 us-gaap Operating Income Loss
OperatingIncomeLoss
-9331000
CY2011Q3 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.27
CY2011Q3 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
33377874 shares
CY2011Q3 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.27
CY2011Q3 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
33377874 shares
CY2011Q3 us-gaap Revenues
Revenues
18955000
CY2011Q3 us-gaap Net Income Loss
NetIncomeLoss
-9054000
CY2012Q3 us-gaap Operating Income Loss
OperatingIncomeLoss
-8098000
CY2012Q3 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.24
CY2012Q3 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
33494106 shares
CY2012Q3 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.24
CY2012Q3 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
33494106 shares
CY2012Q3 us-gaap Revenues
Revenues
768000
CY2012Q3 us-gaap Net Income Loss
NetIncomeLoss
-7879000
CY2011Q4 us-gaap Operating Income Loss
OperatingIncomeLoss
-10145000
CY2011Q4 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.29
CY2011Q4 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
33382640 shares
CY2011Q4 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.29
CY2011Q4 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
33382640 shares
CY2011Q4 us-gaap Revenues
Revenues
18945000
CY2011Q4 us-gaap Net Income Loss
NetIncomeLoss
-9805000
CY2012Q4 us-gaap Operating Income Loss
OperatingIncomeLoss
-16260000
CY2012Q4 us-gaap Earnings Per Share Diluted
EarningsPerShareDiluted
-0.47
CY2012Q4 us-gaap Weighted Average Number Of Diluted Shares Outstanding
WeightedAverageNumberOfDilutedSharesOutstanding
33609867 shares
CY2012Q4 us-gaap Earnings Per Share Basic
EarningsPerShareBasic
-0.47
CY2012Q4 us-gaap Weighted Average Number Of Shares Outstanding Basic
WeightedAverageNumberOfSharesOutstandingBasic
33609867 shares
CY2012Q4 us-gaap Revenues
Revenues
590000
CY2012Q4 us-gaap Net Income Loss
NetIncomeLoss
-15870000

Files In Submission

Name View Source Status
0001193125-13-109464-index-headers.html Edgar Link pending
0001193125-13-109464-index.html Edgar Link pending
0001193125-13-109464.txt Edgar Link pending
0001193125-13-109464-xbrl.zip Edgar Link pending
d455912d10k.htm Edgar Link pending
d455912dex1011.htm Edgar Link pending
d455912dex1016.htm Edgar Link pending
d455912dex1017.htm Edgar Link pending
d455912dex102.htm Edgar Link pending
d455912dex104a.htm Edgar Link pending
d455912dex231.htm Edgar Link pending
d455912dex311.htm Edgar Link pending
d455912dex312.htm Edgar Link pending
d455912dex321.htm Edgar Link pending
d455912dex322.htm Edgar Link pending
FilingSummary.xml Edgar Link unprocessable
Financial_Report.xls Edgar Link pending
g455912exapg087new.jpg Edgar Link pending
g455912exapg089.jpg Edgar Link pending
g455912exapg090.jpg Edgar Link pending
g455912exapg091.jpg Edgar Link pending
g455912exapg101.jpg Edgar Link pending
g455912g56w25.jpg Edgar Link pending
g455912stamp41.jpg Edgar Link pending
R1.htm Edgar Link pending
R10.htm Edgar Link pending
R11.htm Edgar Link pending
R12.htm Edgar Link pending
R13.htm Edgar Link pending
R14.htm Edgar Link pending
R15.htm Edgar Link pending
R16.htm Edgar Link pending
R17.htm Edgar Link pending
R18.htm Edgar Link pending
R19.htm Edgar Link pending
R2.htm Edgar Link pending
R20.htm Edgar Link pending
R21.htm Edgar Link pending
R22.htm Edgar Link pending
R23.htm Edgar Link pending
R24.htm Edgar Link pending
R25.htm Edgar Link pending
R26.htm Edgar Link pending
R27.htm Edgar Link pending
R28.htm Edgar Link pending
R29.htm Edgar Link pending
R3.htm Edgar Link pending
R30.htm Edgar Link pending
R31.htm Edgar Link pending
R32.htm Edgar Link pending
R33.htm Edgar Link pending
R34.htm Edgar Link pending
R35.htm Edgar Link pending
R36.htm Edgar Link pending
R37.htm Edgar Link pending
R38.htm Edgar Link pending
R39.htm Edgar Link pending
R4.htm Edgar Link pending
R40.htm Edgar Link pending
R41.htm Edgar Link pending
R42.htm Edgar Link pending
R43.htm Edgar Link pending
R44.htm Edgar Link pending
R45.htm Edgar Link pending
R46.htm Edgar Link pending
R47.htm Edgar Link pending
R48.htm Edgar Link pending
R49.htm Edgar Link pending
R5.htm Edgar Link pending
R50.htm Edgar Link pending
R51.htm Edgar Link pending
R52.htm Edgar Link pending
R53.htm Edgar Link pending
R54.htm Edgar Link pending
R55.htm Edgar Link pending
R56.htm Edgar Link pending
R57.htm Edgar Link pending
R58.htm Edgar Link pending
R59.htm Edgar Link pending
R6.htm Edgar Link pending
R60.htm Edgar Link pending
R61.htm Edgar Link pending
R62.htm Edgar Link pending
R7.htm Edgar Link pending
R8.htm Edgar Link pending
R9.htm Edgar Link pending
report.css Edgar Link pending
Show.js Edgar Link pending
trgt-20121231.xml Edgar Link completed
trgt-20121231.xsd Edgar Link pending
trgt-20121231_cal.xml Edgar Link unprocessable
trgt-20121231_def.xml Edgar Link unprocessable
trgt-20121231_lab.xml Edgar Link unprocessable
trgt-20121231_pre.xml Edgar Link unprocessable